Reviewed By
Overview
SCIENTIFIC SCORE
Possibly Effective
Based on 21 Researches
7.4
USERS' SCORE
Moderately Good
Based on 5 Reviews
7.9
Supplement Facts
Serving Size: 1 Softgel
Amount Per Serving
%DV
Vitamin D3 (as Cholecalciferol) (from Lanolin)
125 mcg (5,000 IU)
625%
Top Medical Research Studies
8
We set out to explore the connection between serum vitamin D levels and urinary tract infections (UTIs) in children. Our thorough investigation involved a systematic review and meta-analysis of various studies, including 12 case-control studies and a cross-sectional study. This comprehensive analysis incorporated data from a total of 839 children suffering from UTIs and 929 healthy controls.
Through our analysis, we observed that children diagnosed with UTIs had notably lower levels of serum vitamin D when compared to healthier counterparts. The findings indicated that low vitamin D levels were indeed associated with a higher likelihood of experiencing a UTI, with a significant increase in this risk for children whose vitamin D levels fell below 20 ng/mL. Specifically, children with vitamin D levels under this threshold had a much higher risk of developing UTIs.
Overall, our review strengthens the case for considering vitamin D levels as a potential risk factor in urinary tract infections among children, especially when those levels drop below the critical point.
Through our analysis, we observed that children diagnosed with UTIs had notably lower levels of serum vitamin D when compared to healthier counterparts. The findings indicated that low vitamin D levels were indeed associated with a higher likelihood of experiencing a UTI, with a significant increase in this risk for children whose vitamin D levels fell below 20 ng/mL. Specifically, children with vitamin D levels under this threshold had a much higher risk of developing UTIs.
Overall, our review strengthens the case for considering vitamin D levels as a potential risk factor in urinary tract infections among children, especially when those levels drop below the critical point.
Read More
8
We set out to explore the link between vitamin D deficiency and urinary tract infections (UTIs) in children. Our research included a well-defined case-control study with children aged one to five years. We compared 82 children experiencing their first febrile UTI to 82 healthy peers.
By measuring vitamin D levels in their blood, we found that children suffering from UTIs had significantly lower levels of 25-hydroxy vitamin D. The average level in the UTI group was 24.27 ng/mL, while the control group had a healthier average of 31.97 ng/mL. Alarmingly, we discovered that 41.5% of the children with UTIs were vitamin D deficient compared to just 2.2% in the healthy group.
Our study indicates that low vitamin D levels may indeed be a risk factor for UTIs in young children. This finding sheds light on an important aspect of pediatric health that could lead to better prevention strategies for these infections.
By measuring vitamin D levels in their blood, we found that children suffering from UTIs had significantly lower levels of 25-hydroxy vitamin D. The average level in the UTI group was 24.27 ng/mL, while the control group had a healthier average of 31.97 ng/mL. Alarmingly, we discovered that 41.5% of the children with UTIs were vitamin D deficient compared to just 2.2% in the healthy group.
Our study indicates that low vitamin D levels may indeed be a risk factor for UTIs in young children. This finding sheds light on an important aspect of pediatric health that could lead to better prevention strategies for these infections.
Read More
8
Vitamin D deficiency increases UTI risk
We explored the link between vitamin D levels and late-onset urinary tract infections (UTIs) among kidney transplant recipients. Our study analyzed data from 2,207 individuals who had measurements of their vitamin D levels after transplantation.
We found that lower levels of circulating vitamin D were associated with a higher risk of developing late-onset infections. Specifically, every time the vitamin D level dropped by 5 ng/mL, the risk of infection increased by 5%. This connection was notably stronger for urinary tract infections, particularly in male recipients, showing a more than twofold increase in risk for those with vitamin D deficiency.
These findings suggest that maintaining adequate vitamin D levels could be a valuable strategy in preventing infections after kidney transplants. However, further research, including clinical trials, will be crucial to determine a clear causal relationship between vitamin D and urinary tract infections.
We found that lower levels of circulating vitamin D were associated with a higher risk of developing late-onset infections. Specifically, every time the vitamin D level dropped by 5 ng/mL, the risk of infection increased by 5%. This connection was notably stronger for urinary tract infections, particularly in male recipients, showing a more than twofold increase in risk for those with vitamin D deficiency.
These findings suggest that maintaining adequate vitamin D levels could be a valuable strategy in preventing infections after kidney transplants. However, further research, including clinical trials, will be crucial to determine a clear causal relationship between vitamin D and urinary tract infections.
Read More
Most Useful Reviews
9
Improved immunity
2 people found this helpful
I purchased this vitamin as I lack sunlight. I've felt fatigued and suffered from pain in my back and legs, likely due to vitamin D3 deficiency. After six days of taking it, I noticed increased energy, improved mood, and less pain. It’s beneficial for immunity and may assist in preventing respiratory infections.
Read More
9
Enhanced resilience
2 people found this helpful
I have taken D3 for a year, with no winter illnesses for me and my husband. My complexion has improved, and I have experienced fewer bruises under my eyes. After struggling for 8 years, I successfully became pregnant. For thrush or cystitis symptoms, increasing my dose resolves issues quickly.
Read More
9
Family immunity boost
2 people found this helpful
My family takes vitamin D daily, which supports bone, muscle, and nervous system health. Studies show that many COVID-19 patients had low vitamin D levels. I take 5000 units daily, and it helps reduce the risk of respiratory infections. Each family member has their own dosage to ensure optimal vitamin intake.
Read More
Medical Researches
SCIENTIFIC SCORE
Possibly Effective
Based on 21 Researches
7.4
- All Researches
8
Vitamin D deficiency increases UTI risk
We explored the link between vitamin D levels and late-onset urinary tract infections (UTIs) among kidney transplant recipients. Our study analyzed data from 2,207 individuals who had measurements of their vitamin D levels after transplantation.
We found that lower levels of circulating vitamin D were associated with a higher risk of developing late-onset infections. Specifically, every time the vitamin D level dropped by 5 ng/mL, the risk of infection increased by 5%. This connection was notably stronger for urinary tract infections, particularly in male recipients, showing a more than twofold increase in risk for those with vitamin D deficiency.
These findings suggest that maintaining adequate vitamin D levels could be a valuable strategy in preventing infections after kidney transplants. However, further research, including clinical trials, will be crucial to determine a clear causal relationship between vitamin D and urinary tract infections.
We found that lower levels of circulating vitamin D were associated with a higher risk of developing late-onset infections. Specifically, every time the vitamin D level dropped by 5 ng/mL, the risk of infection increased by 5%. This connection was notably stronger for urinary tract infections, particularly in male recipients, showing a more than twofold increase in risk for those with vitamin D deficiency.
These findings suggest that maintaining adequate vitamin D levels could be a valuable strategy in preventing infections after kidney transplants. However, further research, including clinical trials, will be crucial to determine a clear causal relationship between vitamin D and urinary tract infections.
Read More
We explored the relationship between vitamin D levels and urinary tract infections (UTIs) in children. In our study, we assessed the serum vitamin D and zinc levels among two groups: 40 healthy children and 40 children suffering from UTIs, ensuring that no other health factors influenced the results.
Our findings revealed a stark difference between the groups. A staggering 80% of the children with UTIs had vitamin D deficiency, compared to only 17.5% in the healthy group. This significant gap raised an interesting question: could low vitamin D levels contribute to the likelihood of developing UTIs in children?
We also noted that low zinc levels paralleled vitamin D deficiency, with 60% of UTI patients showing zinc insufficiency compared to just 17.5% in the healthy cohort. This observation suggests that both nutrients might be crucial for maintaining a healthy immune response, particularly in young children.
Overall, our study highlights the potential importance of addressing vitamin D levels in children prone to UTIs. Supplementing with vitamin D and zinc could become a vital strategy in not only treating infections but also preventing future occurrences.
Our findings revealed a stark difference between the groups. A staggering 80% of the children with UTIs had vitamin D deficiency, compared to only 17.5% in the healthy group. This significant gap raised an interesting question: could low vitamin D levels contribute to the likelihood of developing UTIs in children?
We also noted that low zinc levels paralleled vitamin D deficiency, with 60% of UTI patients showing zinc insufficiency compared to just 17.5% in the healthy cohort. This observation suggests that both nutrients might be crucial for maintaining a healthy immune response, particularly in young children.
Overall, our study highlights the potential importance of addressing vitamin D levels in children prone to UTIs. Supplementing with vitamin D and zinc could become a vital strategy in not only treating infections but also preventing future occurrences.
Read More
8
We set out to explore the connection between serum vitamin D levels and urinary tract infections (UTIs) in children. Our thorough investigation involved a systematic review and meta-analysis of various studies, including 12 case-control studies and a cross-sectional study. This comprehensive analysis incorporated data from a total of 839 children suffering from UTIs and 929 healthy controls.
Through our analysis, we observed that children diagnosed with UTIs had notably lower levels of serum vitamin D when compared to healthier counterparts. The findings indicated that low vitamin D levels were indeed associated with a higher likelihood of experiencing a UTI, with a significant increase in this risk for children whose vitamin D levels fell below 20 ng/mL. Specifically, children with vitamin D levels under this threshold had a much higher risk of developing UTIs.
Overall, our review strengthens the case for considering vitamin D levels as a potential risk factor in urinary tract infections among children, especially when those levels drop below the critical point.
Through our analysis, we observed that children diagnosed with UTIs had notably lower levels of serum vitamin D when compared to healthier counterparts. The findings indicated that low vitamin D levels were indeed associated with a higher likelihood of experiencing a UTI, with a significant increase in this risk for children whose vitamin D levels fell below 20 ng/mL. Specifically, children with vitamin D levels under this threshold had a much higher risk of developing UTIs.
Overall, our review strengthens the case for considering vitamin D levels as a potential risk factor in urinary tract infections among children, especially when those levels drop below the critical point.
Read More
8
We set out to explore the link between vitamin D deficiency and urinary tract infections (UTIs) in children. Our research included a well-defined case-control study with children aged one to five years. We compared 82 children experiencing their first febrile UTI to 82 healthy peers.
By measuring vitamin D levels in their blood, we found that children suffering from UTIs had significantly lower levels of 25-hydroxy vitamin D. The average level in the UTI group was 24.27 ng/mL, while the control group had a healthier average of 31.97 ng/mL. Alarmingly, we discovered that 41.5% of the children with UTIs were vitamin D deficient compared to just 2.2% in the healthy group.
Our study indicates that low vitamin D levels may indeed be a risk factor for UTIs in young children. This finding sheds light on an important aspect of pediatric health that could lead to better prevention strategies for these infections.
By measuring vitamin D levels in their blood, we found that children suffering from UTIs had significantly lower levels of 25-hydroxy vitamin D. The average level in the UTI group was 24.27 ng/mL, while the control group had a healthier average of 31.97 ng/mL. Alarmingly, we discovered that 41.5% of the children with UTIs were vitamin D deficient compared to just 2.2% in the healthy group.
Our study indicates that low vitamin D levels may indeed be a risk factor for UTIs in young children. This finding sheds light on an important aspect of pediatric health that could lead to better prevention strategies for these infections.
Read More
8
We conducted a study to investigate the relationship between vitamin D levels and urinary tract infections (UTIs) in children. This case-control research involved 80 children, aged between 1 and 12 years, who had been diagnosed with UTIs. For every child in the UTI group, we matched a control child of the same age and sex who did not have a UTI.
We measured the serum vitamin D levels using a method called ELISA. The results were telling. Our findings revealed that children with UTIs had significantly lower levels of vitamin D compared to their healthy peers. In fact, the odds of having a UTI were more than three times greater for those with low vitamin D levels.
Interestingly, we observed that this connection was particularly pronounced in female children. They showed an even higher risk of UTI when their vitamin D levels were low. As for male children, we didn't find a significant difference in vitamin D levels between those with UTIs and those without.
Our conclusions highlight a vital relationship between vitamin D deficiency and the prevalence of UTIs in children. Not only does vitamin D deficiency appear to increase the risk of UTIs, but female gender also seems to be a prominent risk factor.
We measured the serum vitamin D levels using a method called ELISA. The results were telling. Our findings revealed that children with UTIs had significantly lower levels of vitamin D compared to their healthy peers. In fact, the odds of having a UTI were more than three times greater for those with low vitamin D levels.
Interestingly, we observed that this connection was particularly pronounced in female children. They showed an even higher risk of UTI when their vitamin D levels were low. As for male children, we didn't find a significant difference in vitamin D levels between those with UTIs and those without.
Our conclusions highlight a vital relationship between vitamin D deficiency and the prevalence of UTIs in children. Not only does vitamin D deficiency appear to increase the risk of UTIs, but female gender also seems to be a prominent risk factor.
Read More
User Reviews
USERS' SCORE
Moderately Good
Based on 5 Reviews
7.9
- All Reviews
- Positive Reviews
- Negative Reviews
9
Improved immunity
2 people found this helpful
I purchased this vitamin as I lack sunlight. I've felt fatigued and suffered from pain in my back and legs, likely due to vitamin D3 deficiency. After six days of taking it, I noticed increased energy, improved mood, and less pain. It’s beneficial for immunity and may assist in preventing respiratory infections.
Read More
9
Enhanced resilience
2 people found this helpful
I have taken D3 for a year, with no winter illnesses for me and my husband. My complexion has improved, and I have experienced fewer bruises under my eyes. After struggling for 8 years, I successfully became pregnant. For thrush or cystitis symptoms, increasing my dose resolves issues quickly.
Read More
9
Family immunity boost
2 people found this helpful
My family takes vitamin D daily, which supports bone, muscle, and nervous system health. Studies show that many COVID-19 patients had low vitamin D levels. I take 5000 units daily, and it helps reduce the risk of respiratory infections. Each family member has their own dosage to ensure optimal vitamin intake.
Read More
2
Potential complications
I took 5000 IU of Vitamin D and choline daily and developed urinary stones. I'm unsure if the choline helped the vitamin or if both contributed to this issue. While the product isn’t strictly good or bad, I learned that too much of anything can be detrimental, particularly regarding urinary tract infections.
Read More
6
Enhanced immune response
21 people found this helpful
I have been taking vitamin D-3 daily with meals for three months. I feel my body copes better with colds and viral infections. Previously, illnesses progressed quickly, requiring stronger interventions. Now, my immune system manages initial symptoms with less effort. Overall, D-3 is a reliable support for our immune health, especially during a pandemic.
Read More
Frequently Asked Questions
9
Improved immunity
2 people found this helpful
I purchased this vitamin as I lack sunlight. I've felt fatigued and suffered from pain in my back and legs, likely due to vitamin D3 deficiency. After six days of taking it, I noticed increased energy, improved mood, and less pain. It’s beneficial for immunity and may assist in preventing respiratory infections.
9
Enhanced resilience
2 people found this helpful
I have taken D3 for a year, with no winter illnesses for me and my husband. My complexion has improved, and I have experienced fewer bruises under my eyes. After struggling for 8 years, I successfully became pregnant. For thrush or cystitis symptoms, increasing my dose resolves issues quickly.
6
Enhanced immune response
21 people found this helpful
I have been taking vitamin D-3 daily with meals for three months. I feel my body copes better with colds and viral infections. Previously, illnesses progressed quickly, requiring stronger interventions. Now, my immune system manages initial symptoms with less effort. Overall, D-3 is a reliable support for our immune health, especially during a pandemic.
2
Potential complications
I took 5000 IU of Vitamin D and choline daily and developed urinary stones. I'm unsure if the choline helped the vitamin or if both contributed to this issue. While the product isn’t strictly good or bad, I learned that too much of anything can be detrimental, particularly regarding urinary tract infections.
We explored the relationship between vitamin D levels and urinary tract infections (UTIs) in children. In our study, we assessed the serum vitamin D and zinc levels among two groups: 40 healthy children and 40 children suffering from UTIs, ensuring that no other health factors influenced the results.
Our findings revealed a stark difference between the groups. A staggering 80% of the children with UTIs had vitamin D deficiency, compared to only 17.5% in the healthy group. This significant gap raised an interesting question: could low vitamin D levels contribute to the likelihood of developing UTIs in children?
We also noted that low zinc levels paralleled vitamin D deficiency, with 60% of UTI patients showing zinc insufficiency compared to just 17.5% in the healthy cohort. This observation suggests that both nutrients might be crucial for maintaining a healthy immune response, particularly in young children.
Overall, our study highlights the potential importance of addressing vitamin D levels in children prone to UTIs. Supplementing with vitamin D and zinc could become a vital strategy in not only treating infections but also preventing future occurrences.
Our findings revealed a stark difference between the groups. A staggering 80% of the children with UTIs had vitamin D deficiency, compared to only 17.5% in the healthy group. This significant gap raised an interesting question: could low vitamin D levels contribute to the likelihood of developing UTIs in children?
We also noted that low zinc levels paralleled vitamin D deficiency, with 60% of UTI patients showing zinc insufficiency compared to just 17.5% in the healthy cohort. This observation suggests that both nutrients might be crucial for maintaining a healthy immune response, particularly in young children.
Overall, our study highlights the potential importance of addressing vitamin D levels in children prone to UTIs. Supplementing with vitamin D and zinc could become a vital strategy in not only treating infections but also preventing future occurrences.
8
We set out to explore the connection between serum vitamin D levels and urinary tract infections (UTIs) in children. Our thorough investigation involved a systematic review and meta-analysis of various studies, including 12 case-control studies and a cross-sectional study. This comprehensive analysis incorporated data from a total of 839 children suffering from UTIs and 929 healthy controls.
Through our analysis, we observed that children diagnosed with UTIs had notably lower levels of serum vitamin D when compared to healthier counterparts. The findings indicated that low vitamin D levels were indeed associated with a higher likelihood of experiencing a UTI, with a significant increase in this risk for children whose vitamin D levels fell below 20 ng/mL. Specifically, children with vitamin D levels under this threshold had a much higher risk of developing UTIs.
Overall, our review strengthens the case for considering vitamin D levels as a potential risk factor in urinary tract infections among children, especially when those levels drop below the critical point.
Through our analysis, we observed that children diagnosed with UTIs had notably lower levels of serum vitamin D when compared to healthier counterparts. The findings indicated that low vitamin D levels were indeed associated with a higher likelihood of experiencing a UTI, with a significant increase in this risk for children whose vitamin D levels fell below 20 ng/mL. Specifically, children with vitamin D levels under this threshold had a much higher risk of developing UTIs.
Overall, our review strengthens the case for considering vitamin D levels as a potential risk factor in urinary tract infections among children, especially when those levels drop below the critical point.
4
We explored the connection between vitamin D deficiency and urinary tract infections (UTIs) among women of reproductive age. In this study, we analyzed a group of 75 women suffering from UTIs and compared them to a control group of 35 healthy women who did not have UTIs.
Our objective was clear: to understand whether low levels of vitamin D could increase the risk of developing frequent UTIs. This is particularly relevant because women in this age group have unique anatomical features that make them more vulnerable to infections.
Using an ELISA test, we measured the serum levels of 25-hydroxyvitamin D in both groups. The findings were significant; the average vitamin D levels in women with UTIs were noticeably lower—11.09 ng/mL compared to 24.08 ng/mL in the healthy group—which strongly suggests a link between vitamin D deficiency and the incidence of UTIs.
By uncovering this relationship, our findings highlight the importance of monitoring vitamin D levels, as it may play a role in reducing the prevalence of urinary tract infections among women.
Our objective was clear: to understand whether low levels of vitamin D could increase the risk of developing frequent UTIs. This is particularly relevant because women in this age group have unique anatomical features that make them more vulnerable to infections.
Using an ELISA test, we measured the serum levels of 25-hydroxyvitamin D in both groups. The findings were significant; the average vitamin D levels in women with UTIs were noticeably lower—11.09 ng/mL compared to 24.08 ng/mL in the healthy group—which strongly suggests a link between vitamin D deficiency and the incidence of UTIs.
By uncovering this relationship, our findings highlight the importance of monitoring vitamin D levels, as it may play a role in reducing the prevalence of urinary tract infections among women.
5
We focused on the relationship between vitamin D and urinary tract infections (UTIs) caused by uropathogenic E. coli (UPEC). Our study involved examining serum levels of 25-hydroxyvitamin D alongside various immune mediators in a group of 65 patients experiencing UTI, compared to 45 healthy individuals.
Interestingly, we found that the vitamin D levels were slightly lower in patients with UTI, but this decrease wasn't statistically significant. However, we did observe that higher levels of certain immune markers, such as interferon-gamma and interleukin-17A, were positively linked to the amount of vitamin D present. This suggests that vitamin D may play a role in modulating the immune response during a UPEC infection.
Despite these findings, it’s important to note that vitamin D treatment did not show a significant clinical benefit regarding the resolution of urinary tract infections. It appears that while vitamin D may support immune function, further research is needed to fully understand its potential role in UTI management.
Interestingly, we found that the vitamin D levels were slightly lower in patients with UTI, but this decrease wasn't statistically significant. However, we did observe that higher levels of certain immune markers, such as interferon-gamma and interleukin-17A, were positively linked to the amount of vitamin D present. This suggests that vitamin D may play a role in modulating the immune response during a UPEC infection.
Despite these findings, it’s important to note that vitamin D treatment did not show a significant clinical benefit regarding the resolution of urinary tract infections. It appears that while vitamin D may support immune function, further research is needed to fully understand its potential role in UTI management.
8
Cholecalciferol helps prevent UTIs
We explored the potential benefits of cholecalciferol, commonly known as vitamin D3, in preventing recurrent urinary tract infections (UTIs) among patients with benign prostatic hyperplasia (BPH).
In this study, we followed 389 men suffering from moderate to severe BPH symptoms for two years. The patients were divided into two groups: one received tamsulosin, a standard medication to treat BPH, while the other group received both tamsulosin and cholecalciferol.
Our findings revealed that the group treated with cholecalciferol had a significantly lower incidence of UTIs—4.6% compared to 13.5% in the group receiving only tamsulosin. Additionally, the patients who took vitamin D3 experienced a lower level of prostate-specific antigen (PSA) at the end of the treatment, suggesting a potential added benefit.
Overall, cholecalciferol supplementation appears to offer protective effects against recurrent UTIs for BPH patients on tamsulosin, and it does this without introducing any extra adverse effects.
In this study, we followed 389 men suffering from moderate to severe BPH symptoms for two years. The patients were divided into two groups: one received tamsulosin, a standard medication to treat BPH, while the other group received both tamsulosin and cholecalciferol.
Our findings revealed that the group treated with cholecalciferol had a significantly lower incidence of UTIs—4.6% compared to 13.5% in the group receiving only tamsulosin. Additionally, the patients who took vitamin D3 experienced a lower level of prostate-specific antigen (PSA) at the end of the treatment, suggesting a potential added benefit.
Overall, cholecalciferol supplementation appears to offer protective effects against recurrent UTIs for BPH patients on tamsulosin, and it does this without introducing any extra adverse effects.
References
- Yuan Z, Melamed ML, Parajuli S, Mandelbrot D, Astor BC. Association of Posttransplant Circulating 25-Hydroxyvitamin D and Late-Onset Infections Among Kidney Transplant Recipients: The Wisconsin Allograft Recipient Database (WisARD). Transpl Infect Dis. 2025. 10.1111/tid.70016
- Han Z, Yi X, Li J, Liao D, Ai J. Nonantibiotic prophylaxis for urinary tract infections: a network meta-analysis of randomized controlled trials. Infection. 2024. 10.1007/s15010-024-02357-z
- Seifollahi M, Heidarzadeh Arani M, Hoseini Shamsabadi R, Nakhaie S, Karimi Aghche M, et al. Serum Vitamin D and Zinc Levels in Children with Urinary Tract Infection without Confounding Factors: A Case-Control Study. Med J Islam Repub Iran. 2024;38:36. 10.47176/mjiri.38.36
- Gan Y, You S, Ying J, Mu D. The Association between Serum Vitamin D Levels and Urinary Tract Infection Risk in Children: A Systematic Review and Meta-Analysis. Nutrients. 2023;15. 10.3390/nu15122690
- Chidambaram S, Pasupathy U, Geminiganesan S, R D. The Association Between Vitamin D and Urinary Tract Infection in Children: A Case-Control Study. Cureus. 2022;14:e25291. 10.7759/cureus.25291
- Sadeghzadeh M, Khoshnevisasl P, Motamed N, Faghfouri L. The serum vitamin D levels in children with urinary tract infection: a case-control study. New Microbes New Infect. 2021;43:100911. 10.1016/j.nmni.2021.100911
- Qadir S, Memon S, Chohan MN, Memon Y. Frequency of Vitamin-D deficiency in children with Urinary tract infection: A descriptive cross-sectional study. Pak J Med Sci. 2021;37:1058. 10.12669/pjms.37.4.3896
- Muntean C, Săsăran M. Vitamin D Status and Its Role in First-Time and Recurrent Urinary Tract Infections in Children: A Case-Control Study. Children (Basel). 2021;8. 10.3390/children8050419
- Habibi M, Azimi S, Khoobbakht D, Roghanian P, Asadi Karam MR. Immunization with recombinant protein Ag43::UpaH with alum and 1,25(OH)2D3 adjuvants significantly protects Balb/C mice against urinary tract infection caused by uropathogenic Escherichia coli. Int Immunopharmacol. 2021;96:107638. 10.1016/j.intimp.2021.107638
- Li X, Yu Q, Qin F, Zhang B, Lu Y. Serum Vitamin D Level and the Risk of Urinary Tract Infection in Children: A Systematic Review and Meta-Analysis. Front Public Health. 2021;9:637529. 10.3389/fpubh.2021.637529
- Pirdel L, Pirdel M. A Differential Immune Modulating Role of Vitamin D in Urinary Tract Infection. Immunol Invest. 2022;51:531. 10.1080/08820139.2020.1845723
- Sürmeli Döven S, Erdoğan S. Vitamin D deficiency as a risk factor for renal scarring in recurrent urinary tract infections. Pediatr Int. 2021;63:295. 10.1111/ped.14397
- Ali SB, Perdawood D, Abdulrahman R, Al Farraj DA, Alkubaisi NA. Vitamin D deficiency as a risk factor for urinary tract infection in women at reproductive age. Saudi J Biol Sci. 2020;27:2942. 10.1016/j.sjbs.2020.08.008
- Al-Shukri AS, Maksimova AV, Dub NI, Kostyukov SV, Manchenko AA, et al. [Prevention of the development of catheter-associated urinary system infections in the early postoperative period]. Urologiia. 2023.
- Pham H, Waterhouse M, Baxter C, Duarte Romero B, McLeod DSA, et al. Vitamin D Supplementation and Antibiotic Use in Older Australian Adults: An Analysis of Data From the D-Health Trial. J Infect Dis. 2022;226:949. 10.1093/infdis/jiac279
- Mohanty S, Kamolvit W, Hertting O, Brauner A. Vitamin D strengthens the bladder epithelial barrier by inducing tight junction proteins during E. coli urinary tract infection. Cell Tissue Res. 2020;380:669. 10.1007/s00441-019-03162-z
- Safwat AS, Hasanain A, Shahat A, AbdelRazek M, Orabi H, et al. Cholecalciferol for the prophylaxis against recurrent urinary tract infection among patients with benign prostatic hyperplasia: a randomized, comparative study. World J Urol. 2019;37:1347. 10.1007/s00345-018-2536-8
- Kwon YE, Kim H, Oh HJ, Park JT, Han SH, et al. Vitamin D deficiency is an independent risk factor for urinary tract infections after renal transplants. Medicine (Baltimore). 2015;94:e594. 10.1097/MD.0000000000000594
- Ramos NL, Sekikubo M, Kironde F, Mirembe F, Sääf M, et al. The impact of vitamin D on the innate immune response to uropathogenic Escherichia coli during pregnancy. Clin Microbiol Infect. 2015;21:482.e1. 10.1016/j.cmi.2014.12.010
- Tekin M, Konca C, Celik V, Almis H, Kahramaner Z, et al. The Association between Vitamin D Levels and Urinary Tract Infection in Children. Horm Res Paediatr. 2015;83:198. 10.1159/000370046
- Hertting O, Holm Å, Lüthje P, Brauner H, Dyrdak R, et al. Vitamin D induction of the human antimicrobial Peptide cathelicidin in the urinary bladder. PLoS One. 2010;5:e15580. 10.1371/journal.pone.0015580
