Overview
SCIENTIFIC SCORE
Possibly Effective
Based on 8 Researches
7.9
USERS' SCORE
Good
Based on 2 Reviews
8.5
Supplement Facts
Serving Size: 1 Veg Capsule
Amount Per Serving
%DV
Vitamin D2 (as Ergocalciferol)
25 mcg (1,000 IU)
125%
Top Medical Research Studies
8
We explored the potential connection between vitamin D levels and headaches through a thorough investigation using two-sample Mendelian randomization analysis. Our goal was to determine if there’s a causal relationship between high vitamin D levels and the risk of experiencing headaches.
Our findings revealed that higher levels of vitamin D are linked to a lower risk of headaches. Specifically, we found that vitamin D may have a preventive effect, reducing the likelihood of headaches occurring. However, we also observed that there is no evidence to suggest that headaches cause changes in vitamin D levels.
This means while supplementing vitamin D may help keep headaches at bay, headaches themselves do not appear to affect vitamin D levels. This information contributes valuable insights into how maintaining sufficient vitamin D could play a role in headache management.
Our findings revealed that higher levels of vitamin D are linked to a lower risk of headaches. Specifically, we found that vitamin D may have a preventive effect, reducing the likelihood of headaches occurring. However, we also observed that there is no evidence to suggest that headaches cause changes in vitamin D levels.
This means while supplementing vitamin D may help keep headaches at bay, headaches themselves do not appear to affect vitamin D levels. This information contributes valuable insights into how maintaining sufficient vitamin D could play a role in headache management.
Read More
8
We aimed to investigate how vitamin D levels might impact migraine occurrences in children. Recent research highlighted that many youngsters experience migraines, and intriguingly, vitamin D has been linked to various neurological conditions.
In diving into existing literature, we found a noteworthy connection between low vitamin D levels and the frequency and duration of migraine attacks in pediatric patients. Our review suggested that vitamin D supplementation could potentially enhance the quality of life for those suffering from migrainous headaches.
While vitamin D is often talked about in terms of its benefits for bone health, its implications for migraine management in children seem promising. We recognized the potential for vitamin D to play a meaningful role in alleviating headaches, especially in a time when many children face this debilitating condition.
In diving into existing literature, we found a noteworthy connection between low vitamin D levels and the frequency and duration of migraine attacks in pediatric patients. Our review suggested that vitamin D supplementation could potentially enhance the quality of life for those suffering from migrainous headaches.
While vitamin D is often talked about in terms of its benefits for bone health, its implications for migraine management in children seem promising. We recognized the potential for vitamin D to play a meaningful role in alleviating headaches, especially in a time when many children face this debilitating condition.
Read More
7
We investigated how vitamin D levels relate to migraines and whether vitamin D supplementation can help people who suffer from these headaches. Our analysis included a range of studies, focusing on differences in vitamin D levels between migraine sufferers and those who do not experience migraines.
We found that migraineurs had significantly lower levels of serum 25-hydroxy vitamin D compared to nonmigraineurs, indicating a noteworthy connection. In fact, vitamin D deficiency was shown to be associated with an increased likelihood of experiencing migraines.
When it comes to treatment, we observed that taking vitamin D supplements seemed to help reduce the frequency of migraines. However, it's important to note that while vitamin D supplementation made a difference in how often migraines occurred, it did not significantly impact how long these headaches lasted or their severity.
Overall, it appears that while vitamin D might help lessen the occurrence of migraines for some, it may not be a solution for everyone, particularly in regards to reducing the intensity or duration of such headaches.
We found that migraineurs had significantly lower levels of serum 25-hydroxy vitamin D compared to nonmigraineurs, indicating a noteworthy connection. In fact, vitamin D deficiency was shown to be associated with an increased likelihood of experiencing migraines.
When it comes to treatment, we observed that taking vitamin D supplements seemed to help reduce the frequency of migraines. However, it's important to note that while vitamin D supplementation made a difference in how often migraines occurred, it did not significantly impact how long these headaches lasted or their severity.
Overall, it appears that while vitamin D might help lessen the occurrence of migraines for some, it may not be a solution for everyone, particularly in regards to reducing the intensity or duration of such headaches.
Read More
Most Useful Reviews
9
No headaches experienced
Perfect! I have struggled to take any form of Vitamin D without suffering from massive headaches for nearly 20 years. Finally, I read about someone similar who switched to D2, and it worked. I'm eagerly awaiting my blood work to show an increase in Vitamin D for the first time in years, but for now, I am taking six capsules a day without any headaches!
Read More
8
No headaches noted
Good Vitamin D! It seems to work well and deliver the desired effects. I’ve told my friends about it, and they’re interested too. There have been no cramps or headaches.
Read More
Medical Researches
SCIENTIFIC SCORE
Possibly Effective
Based on 8 Researches
7.9
- All Researches
9
We conducted a clinical trial to investigate the effects of vitamin D supplementation alongside topiramate, a medication commonly used for migraine prevention in children aged 5 to 14. In this double-blind study, participants were divided into two groups: one received vitamin D with their topiramate treatment, while the other received a placebo.
After four months, we observed that those who took vitamin D experienced a significant reduction in the monthly frequency of headache attacks compared to the placebo group. We noted that children taking vitamin D also reported less disability from their migraines and a higher percentage showed a good response to the treatment.
Furthermore, the side effects were relatively similar between both groups, suggesting that combining vitamin D with topiramate is a safe and well-tolerated option. Overall, our findings indicate that vitamin D supplementation could enhance migraine management in pediatric patients.
After four months, we observed that those who took vitamin D experienced a significant reduction in the monthly frequency of headache attacks compared to the placebo group. We noted that children taking vitamin D also reported less disability from their migraines and a higher percentage showed a good response to the treatment.
Furthermore, the side effects were relatively similar between both groups, suggesting that combining vitamin D with topiramate is a safe and well-tolerated option. Overall, our findings indicate that vitamin D supplementation could enhance migraine management in pediatric patients.
Read More
9
We explored how vitamin D treatment can influence headache severity in patients. In this case study, a 28-year-old woman experienced excessive daytime sleepiness without clear causes such as sleep disorders. Her symptoms included significant fatigue, chronic pain in her thighs and lower back, and daily headaches.
After identifying that she had low levels of vitamin D, we initiated supplementation, which quickly led to notable improvements. Within just a couple of weeks, her headaches improved significantly alongside her daytime tiredness. By the end of the treatment, both her headaches and other chronic pain issues had resolved or greatly diminished.
However, while the study indicates an association between vitamin D treatment and headache relief, it does not specifically isolate the effect of vitamin D2 solely on headaches. Therefore, while we saw encouraging improvements, we must note that further research is needed to establish a more direct link between vitamin D treatment and headache relief specifically.
After identifying that she had low levels of vitamin D, we initiated supplementation, which quickly led to notable improvements. Within just a couple of weeks, her headaches improved significantly alongside her daytime tiredness. By the end of the treatment, both her headaches and other chronic pain issues had resolved or greatly diminished.
However, while the study indicates an association between vitamin D treatment and headache relief, it does not specifically isolate the effect of vitamin D2 solely on headaches. Therefore, while we saw encouraging improvements, we must note that further research is needed to establish a more direct link between vitamin D treatment and headache relief specifically.
Read More
8
Combined treatment benefits migraines
We conducted a randomized, triple-blinded, placebo-controlled trial focusing on the effects of vitamin D and probiotic co-supplementation on migraine headaches. This study included adult patients aged 18 to 55 diagnosed with migraines, specifically using the International Classification of Headache Disorders-3 criteria.
Over a 12-week period, participants received either 50,000 IU of vitamin D plus a daily probiotic or a placebo. We assessed their migraine symptoms through reliable questionnaires and self-reported diaries, tracking headache frequency, duration, and intensity. We also measured their mental health, daily functioning, and inflammation markers during the trial.
Our findings indicated that the combination of vitamin D and probiotics provided beneficial effects on migraine characteristics, including improved mental health outcomes. Although we did not isolate the impact of vitamin D alone, the results suggest that it may play a role in migraine management when paired with probiotics. Further studies are needed to firmly establish these effects and better understand the potential of vitamin D as a treatment option for headaches.
Over a 12-week period, participants received either 50,000 IU of vitamin D plus a daily probiotic or a placebo. We assessed their migraine symptoms through reliable questionnaires and self-reported diaries, tracking headache frequency, duration, and intensity. We also measured their mental health, daily functioning, and inflammation markers during the trial.
Our findings indicated that the combination of vitamin D and probiotics provided beneficial effects on migraine characteristics, including improved mental health outcomes. Although we did not isolate the impact of vitamin D alone, the results suggest that it may play a role in migraine management when paired with probiotics. Further studies are needed to firmly establish these effects and better understand the potential of vitamin D as a treatment option for headaches.
Read More
8
We explored the potential connection between vitamin D levels and headaches through a thorough investigation using two-sample Mendelian randomization analysis. Our goal was to determine if there’s a causal relationship between high vitamin D levels and the risk of experiencing headaches.
Our findings revealed that higher levels of vitamin D are linked to a lower risk of headaches. Specifically, we found that vitamin D may have a preventive effect, reducing the likelihood of headaches occurring. However, we also observed that there is no evidence to suggest that headaches cause changes in vitamin D levels.
This means while supplementing vitamin D may help keep headaches at bay, headaches themselves do not appear to affect vitamin D levels. This information contributes valuable insights into how maintaining sufficient vitamin D could play a role in headache management.
Our findings revealed that higher levels of vitamin D are linked to a lower risk of headaches. Specifically, we found that vitamin D may have a preventive effect, reducing the likelihood of headaches occurring. However, we also observed that there is no evidence to suggest that headaches cause changes in vitamin D levels.
This means while supplementing vitamin D may help keep headaches at bay, headaches themselves do not appear to affect vitamin D levels. This information contributes valuable insights into how maintaining sufficient vitamin D could play a role in headache management.
Read More
8
We aimed to investigate how vitamin D levels might impact migraine occurrences in children. Recent research highlighted that many youngsters experience migraines, and intriguingly, vitamin D has been linked to various neurological conditions.
In diving into existing literature, we found a noteworthy connection between low vitamin D levels and the frequency and duration of migraine attacks in pediatric patients. Our review suggested that vitamin D supplementation could potentially enhance the quality of life for those suffering from migrainous headaches.
While vitamin D is often talked about in terms of its benefits for bone health, its implications for migraine management in children seem promising. We recognized the potential for vitamin D to play a meaningful role in alleviating headaches, especially in a time when many children face this debilitating condition.
In diving into existing literature, we found a noteworthy connection between low vitamin D levels and the frequency and duration of migraine attacks in pediatric patients. Our review suggested that vitamin D supplementation could potentially enhance the quality of life for those suffering from migrainous headaches.
While vitamin D is often talked about in terms of its benefits for bone health, its implications for migraine management in children seem promising. We recognized the potential for vitamin D to play a meaningful role in alleviating headaches, especially in a time when many children face this debilitating condition.
Read More
User Reviews
USERS' SCORE
Good
Based on 2 Reviews
8.5
- All Reviews
- Positive Reviews
- Negative Reviews
9
No headaches experienced
Perfect! I have struggled to take any form of Vitamin D without suffering from massive headaches for nearly 20 years. Finally, I read about someone similar who switched to D2, and it worked. I'm eagerly awaiting my blood work to show an increase in Vitamin D for the first time in years, but for now, I am taking six capsules a day without any headaches!
Read More
8
No headaches noted
Good Vitamin D! It seems to work well and deliver the desired effects. I’ve told my friends about it, and they’re interested too. There have been no cramps or headaches.
Read More
Frequently Asked Questions
No FAQs are available for this product and symptom.
References
- Hao S, Qian R, Chen Y, Liu J, Xu X, et al. Association between serum vitamin D and severe headache or migraine: A population-based analysis. PLoS One. 2025;20:e0313082. doi:10.1371/journal.pone.0313082
- Tirani SA, Khorvash F, Saneei P, Moradmand Z, Askari G. Effects of probiotic and vitamin D co-supplementation on clinical symptoms, mental health, and inflammation in adult patients with migraine headache: a randomized, triple-blinded, placebo-controlled trial. BMC Med. 2024;22:457. doi:10.1186/s12916-024-03684-6
- Xiong H, Jiang R, Xing L, Zheng J, Tian X, et al. New evidence that vitamin D prevents headache: a bidirectional two-sample Mendelian randomization analysis. Front Neurol. 2024;15:1423569. doi:10.3389/fneur.2024.1423569
- Ioannidou E, Tsakiris C, Goulis DG, Christoforidis A, Zafeiriou D. The association of serum vitamin D concentrations in paediatric migraine. Eur J Paediatr Neurol. 2023;47:60. doi:10.1016/j.ejpn.2023.09.007
- Das S, Roy A, Behera SK, Selvarajan S, Kamalanathan S, et al. Effects of Vitamin D on Migraine: A Meta-Analysis. Neurol India. 2023;71:655. doi:10.4103/0028-3886.383862
- Gaul C, Zaranek L, Goßrau G. [Complementary and supplementary procedures in the treatment of headache]. Schmerz. 2023;37:448. doi:10.1007/s00482-023-00738-1
- Kotb Elmala M, Suliman HA, Al-Shokary AH, Ibrahim AO, Kamal NM, et al. The Impact of Vitamin D Supplementation to Topiramate Therapy on Pediatric Migraine Prophylaxis. J Child Neurol. 2022;37:833. doi:10.1177/08830738221092882
- McCarty DE. Resolution of hypersomnia following identification and treatment of vitamin d deficiency. J Clin Sleep Med. 2010;6:605.
