Last update
3/8/2026
Reviewed By
Overview
SCIENTIFIC SCORE
Likely Very Effective
Based on 1 Research
9
USERS' SCORE
Good
Based on 5 Reviews
8.2
Supplement Facts
Serving Size: 1 Veg Capsule
Amount Per Serving
%DV
Vitamin K2 (as Menaquinone-4) (MK-4)
100 mcg
**
Alfalfa Powder (Aerial Parts)
250 mg
**
Top Medical Research Studies
9
We designed a multicenter, double-blind, placebo-controlled trial to explore if vitamin K2 can effectively manage nocturnal leg cramps (NLCs).
Conducted in China with older adults experiencing regular cramps, participants were randomly assigned to receive either vitamin K2 or a placebo for 8 weeks. Remarkably, our findings demonstrated that vitamin K2 significantly reduced the frequency, duration, and intensity of NLCs, making it a promising option for those suffering from this discomfort.
Notably, the treatment showed good safety profiles, reinforcing its potential utility in managing leg cramps.
Conducted in China with older adults experiencing regular cramps, participants were randomly assigned to receive either vitamin K2 or a placebo for 8 weeks. Remarkably, our findings demonstrated that vitamin K2 significantly reduced the frequency, duration, and intensity of NLCs, making it a promising option for those suffering from this discomfort.
Notably, the treatment showed good safety profiles, reinforcing its potential utility in managing leg cramps.
Read More
Most Useful Reviews
9
Heaviness reduced
I purchased this for bone and cardiovascular health and was very pleased! The fact that it is vegetarian suits my dietary preferences. After a month of taking it, I've felt significant positive changes; notably, the heaviness in my legs has greatly diminished, contributing to my overall well-being. The 100 mcg dosage is ideal for daily intake. I intend to continue using it as vitamin K2 is crucial for calcium absorption. I recommend it to anyone concerned about health!
Read More
7
Cramps improved
Cramps improved.
Read More
9
Remarkable effect
I gave this to my mother, and she took it along with vitamin D and calcium. The effect has been remarkable—my mother's leg cramps have stopped. We will continue to take more.
Read More
Medical Researches
SCIENTIFIC SCORE
Likely Very Effective
Based on 1 Research
9
- All Researches
9
We designed a multicenter, double-blind, placebo-controlled trial to explore if vitamin K2 can effectively manage nocturnal leg cramps (NLCs).
Conducted in China with older adults experiencing regular cramps, participants were randomly assigned to receive either vitamin K2 or a placebo for 8 weeks. Remarkably, our findings demonstrated that vitamin K2 significantly reduced the frequency, duration, and intensity of NLCs, making it a promising option for those suffering from this discomfort.
Notably, the treatment showed good safety profiles, reinforcing its potential utility in managing leg cramps.
Conducted in China with older adults experiencing regular cramps, participants were randomly assigned to receive either vitamin K2 or a placebo for 8 weeks. Remarkably, our findings demonstrated that vitamin K2 significantly reduced the frequency, duration, and intensity of NLCs, making it a promising option for those suffering from this discomfort.
Notably, the treatment showed good safety profiles, reinforcing its potential utility in managing leg cramps.
Read More
User Reviews
USERS' SCORE
Good
Based on 5 Reviews
8.2
- All Reviews
- Positive Reviews
- Negative Reviews
9
Heaviness reduced
I purchased this for bone and cardiovascular health and was very pleased! The fact that it is vegetarian suits my dietary preferences. After a month of taking it, I've felt significant positive changes; notably, the heaviness in my legs has greatly diminished, contributing to my overall well-being. The 100 mcg dosage is ideal for daily intake. I intend to continue using it as vitamin K2 is crucial for calcium absorption. I recommend it to anyone concerned about health!
Read More
7
Cramps improved
Cramps improved.
Read More
9
Remarkable effect
I gave this to my mother, and she took it along with vitamin D and calcium. The effect has been remarkable—my mother's leg cramps have stopped. We will continue to take more.
Read More
7.5
Bones hurt less
I took vitamin K2 MK-7 alongside vitamin D to support bone and vascular health, as it directs calcium to bones and teeth while preventing its deposition in arteries. Choosing MK-7 was deliberate, as it is known for its activity and longevity in the body. After a few weeks, I noticed improvements: less bone pain, especially in areas that previously felt uncomfortable, and an overall enhancement in vascular feel, with reduced tiredness and heaviness in my legs. The combination of vitamin K2 MK-7 with vitamin D3 and magnesium is beneficial as it aids calcium absorption. I faced no side effects and was generally pleased with the results.
Read More
6
Lightness in legs
I truly appreciated this product for its quality, ease of use, and positive effects on health. NOW Foods consistently delivers high quality. The composition is transparent, free from unnecessary additives, and the capsules are suitable for vegetarians. Containing menaquinone-7 (MK-7), it offers optimal absorption. After several weeks of use, I noted visible benefits: improved nail and skin condition and a lightness in my legs, indicating enhanced vascular support. A perfect choice for those incorporating vitamin K2 without excess expense.
Read More
Frequently Asked Questions
9
Heaviness reduced
I purchased this for bone and cardiovascular health and was very pleased! The fact that it is vegetarian suits my dietary preferences. After a month of taking it, I've felt significant positive changes; notably, the heaviness in my legs has greatly diminished, contributing to my overall well-being. The 100 mcg dosage is ideal for daily intake. I intend to continue using it as vitamin K2 is crucial for calcium absorption. I recommend it to anyone concerned about health!
9
Remarkable effect
I gave this to my mother, and she took it along with vitamin D and calcium. The effect has been remarkable—my mother's leg cramps have stopped. We will continue to take more.
7.5
Bones hurt less
I took vitamin K2 MK-7 alongside vitamin D to support bone and vascular health, as it directs calcium to bones and teeth while preventing its deposition in arteries. Choosing MK-7 was deliberate, as it is known for its activity and longevity in the body. After a few weeks, I noticed improvements: less bone pain, especially in areas that previously felt uncomfortable, and an overall enhancement in vascular feel, with reduced tiredness and heaviness in my legs. The combination of vitamin K2 MK-7 with vitamin D3 and magnesium is beneficial as it aids calcium absorption. I faced no side effects and was generally pleased with the results.
6
Lightness in legs
I truly appreciated this product for its quality, ease of use, and positive effects on health. NOW Foods consistently delivers high quality. The composition is transparent, free from unnecessary additives, and the capsules are suitable for vegetarians. Containing menaquinone-7 (MK-7), it offers optimal absorption. After several weeks of use, I noted visible benefits: improved nail and skin condition and a lightness in my legs, indicating enhanced vascular support. A perfect choice for those incorporating vitamin K2 without excess expense.
9
We designed a multicenter, double-blind, placebo-controlled trial to explore if vitamin K2 can effectively manage nocturnal leg cramps (NLCs).
Conducted in China with older adults experiencing regular cramps, participants were randomly assigned to receive either vitamin K2 or a placebo for 8 weeks. Remarkably, our findings demonstrated that vitamin K2 significantly reduced the frequency, duration, and intensity of NLCs, making it a promising option for those suffering from this discomfort.
Notably, the treatment showed good safety profiles, reinforcing its potential utility in managing leg cramps.
Conducted in China with older adults experiencing regular cramps, participants were randomly assigned to receive either vitamin K2 or a placebo for 8 weeks. Remarkably, our findings demonstrated that vitamin K2 significantly reduced the frequency, duration, and intensity of NLCs, making it a promising option for those suffering from this discomfort.
Notably, the treatment showed good safety profiles, reinforcing its potential utility in managing leg cramps.
References
- Tan J, Zhu R, Li Y, Wang L, Liao S, et al. Vitamin K2 in Managing Nocturnal Leg Cramps: A Randomized Clinical Trial. JAMA Intern Med. 2024;184:1443. 10.1001/jamainternmed.2024.5726
Data last updated:
