Overview

SCIENTIFIC SCORE
Moderately Effective
Based on 3 Researches
8.7
USERS' SCORE
Moderately Good
Based on 118 Reviews
7.9
Supplement Facts
Serving Size: 1 Softgel
Amount Per Serving
%DV
Vitamin D3 (as Cholecalciferol) (from Lanolin)
50 mcg (2,000 IU)
250%

Top Medical Research Studies

9
Vitamin D3 correction improves pain
We explored the impact of vitamin D3 levels on bone pain that patients experience after undergoing unicompartmental knee arthroplasty (UKA). The study involved 240 participants who were divided into three groups based on their vitamin D status—some received treatment before surgery, some after, and others had normal levels to begin with.

By administering vitamin D3 in three doses, we aimed to see if correcting deficiencies could alleviate post-operative bone pain. Throughout the recovery period, we measured pain levels using the visual analog scale at various intervals after the surgery.

Our findings clearly demonstrated that patients who corrected their vitamin D3 deficiency before surgery reported significantly better pain control after the operation compared to those who were treated afterwards or those who started with adequate levels. This highlights the importance of testing and addressing vitamin D status prior to orthopedic procedures, showing that it is a modifiable risk factor affecting recovery.
Read More
9
Effectiveness of calcitriol combination therapy
We conducted an insightful study to analyze how combining calcitriol, a form of vitamin D, with bisphosphonates affects bone pain in postmenopausal women suffering from osteoporosis. This quasi-experimental approach allowed us to compare two groups: one treated with calcitriol alone and the other with the combination treatment.

Our findings highlighted that adding bisphosphonates to calcitriol significantly alleviated bone pain among the participants. We observed improved evaluations of joint pain through the Visual Analogue Scale/Score, indicating that patients felt much better post-treatment. Furthermore, the combination therapy enhanced the patients' overall daily living capabilities and positively influenced bone metabolism and density.

Overall, our results suggest that calcitriol combined with bisphosphonates is effective in not just relieving pain but also supporting the long-term health of bones in postmenopausal women. This approach may pave the way for improved treatment strategies for osteoporosis in this demographic.
Read More
8
Vitamin D reduces fracture risk
We investigated the connection between vitamin D levels and the risk of new vertebral fractures in postmenopausal women who had undergone percutaneous vertebral augmentation. Through a retrospective case-control study involving patients aged 50 and older, we analyzed records to categorize participants into groups based on whether they experienced refractures and how serum levels of 25-hydroxyvitamin D (25[OH]D) influenced these outcomes.

Our findings revealed that low levels of serum 25(OH)D are linked to an increased risk of new vertebral fractures in these patients. What's noteworthy is that vitamin D plays a crucial role in maintaining bone health, and adequate levels can help reduce the likelihood of subsequent fractures after surgery. This underscores the potential importance of vitamin D supplementation for patients recovering from vertebral augmentation.

In conclusion, ensuring that patients receive appropriate vitamin D intake might be pivotal in preventing further bone pain and fractures following surgery. By addressing vitamin D deficiency, we could significantly improve bone health outcomes and enhance the quality of life for postmenopausal women recovering from vertebral fractures.
Read More

Most Useful Reviews

9
Restored bone health
318 people found this helpful
Vitamin D3 effectively strengthened my bones and boosted immunity. I recommend taking it before the cold season to combat bone pain.
Read More
9
General wellbeing
224 people found this helpful
This is the essential vitamin for my body. The small capsules have helped me recover from bone pain within a month, and my immunity feels stronger.
Read More
10
Pain relief
122 people found this helpful
Prior to taking Vitamin D3, I suffered from crippling bone pain. After just one week, I feel revitalised and energetic, and the pain is gone.
Read More

Medical Researches

SCIENTIFIC SCORE
Moderately Effective
Based on 3 Researches
8.7
  • All Researches
9
Vitamin D3 correction improves pain
We explored the impact of vitamin D3 levels on bone pain that patients experience after undergoing unicompartmental knee arthroplasty (UKA). The study involved 240 participants who were divided into three groups based on their vitamin D status—some received treatment before surgery, some after, and others had normal levels to begin with.

By administering vitamin D3 in three doses, we aimed to see if correcting deficiencies could alleviate post-operative bone pain. Throughout the recovery period, we measured pain levels using the visual analog scale at various intervals after the surgery.

Our findings clearly demonstrated that patients who corrected their vitamin D3 deficiency before surgery reported significantly better pain control after the operation compared to those who were treated afterwards or those who started with adequate levels. This highlights the importance of testing and addressing vitamin D status prior to orthopedic procedures, showing that it is a modifiable risk factor affecting recovery.
Read More
9
Effectiveness of calcitriol combination therapy
We conducted an insightful study to analyze how combining calcitriol, a form of vitamin D, with bisphosphonates affects bone pain in postmenopausal women suffering from osteoporosis. This quasi-experimental approach allowed us to compare two groups: one treated with calcitriol alone and the other with the combination treatment.

Our findings highlighted that adding bisphosphonates to calcitriol significantly alleviated bone pain among the participants. We observed improved evaluations of joint pain through the Visual Analogue Scale/Score, indicating that patients felt much better post-treatment. Furthermore, the combination therapy enhanced the patients' overall daily living capabilities and positively influenced bone metabolism and density.

Overall, our results suggest that calcitriol combined with bisphosphonates is effective in not just relieving pain but also supporting the long-term health of bones in postmenopausal women. This approach may pave the way for improved treatment strategies for osteoporosis in this demographic.
Read More
8
Vitamin D reduces fracture risk
We investigated the connection between vitamin D levels and the risk of new vertebral fractures in postmenopausal women who had undergone percutaneous vertebral augmentation. Through a retrospective case-control study involving patients aged 50 and older, we analyzed records to categorize participants into groups based on whether they experienced refractures and how serum levels of 25-hydroxyvitamin D (25[OH]D) influenced these outcomes.

Our findings revealed that low levels of serum 25(OH)D are linked to an increased risk of new vertebral fractures in these patients. What's noteworthy is that vitamin D plays a crucial role in maintaining bone health, and adequate levels can help reduce the likelihood of subsequent fractures after surgery. This underscores the potential importance of vitamin D supplementation for patients recovering from vertebral augmentation.

In conclusion, ensuring that patients receive appropriate vitamin D intake might be pivotal in preventing further bone pain and fractures following surgery. By addressing vitamin D deficiency, we could significantly improve bone health outcomes and enhance the quality of life for postmenopausal women recovering from vertebral fractures.
Read More

User Reviews

USERS' SCORE
Moderately Good
Based on 118 Reviews
7.9
  • All Reviews
  • Positive Reviews
  • Negative Reviews
9
Restored bone health
318 people found this helpful
Vitamin D3 effectively strengthened my bones and boosted immunity. I recommend taking it before the cold season to combat bone pain.
Read More
9
General wellbeing
224 people found this helpful
This is the essential vitamin for my body. The small capsules have helped me recover from bone pain within a month, and my immunity feels stronger.
Read More
10
Pain relief
122 people found this helpful
Prior to taking Vitamin D3, I suffered from crippling bone pain. After just one week, I feel revitalised and energetic, and the pain is gone.
Read More
10
Improved immunity
119 people found this helpful
This vitamin D3 has been a lifesaver for my deficiency. The small, tasteless capsules are easy to take, and I follow my doctor's prescription diligently. My immunity has noticeably improved, and my bone pain has also stopped. The product is free from harmful additives, and after a month, I’ve resolved my deficiency. I also provide it to my children in the colder months.
Read More
9
Boosted energy
87 people found this helpful
My experience with these vitamins began with taking vitamin D3, which alleviated my constant weakness and bone pain. After taking it, I felt revitalised, especially vital for those in northern latitudes during long winters.
Read More

Frequently Asked Questions

10
Pain relief
122 people found this helpful
Prior to taking Vitamin D3, I suffered from crippling bone pain. After just one week, I feel revitalised and energetic, and the pain is gone.
9
Miraculous relief
19 people found this helpful
My miracle has arrived! Before taking Vitamin D3, I suffered crippling pain in my joints and muscles. After just one week of use, I feel vibrant and more energetic, wholly transforming my previous experience of bone pain.
9
General wellbeing
224 people found this helpful
This is the essential vitamin for my body. The small capsules have helped me recover from bone pain within a month, and my immunity feels stronger.
10
Improved immunity
119 people found this helpful
This vitamin D3 has been a lifesaver for my deficiency. The small, tasteless capsules are easy to take, and I follow my doctor's prescription diligently. My immunity has noticeably improved, and my bone pain has also stopped. The product is free from harmful additives, and after a month, I’ve resolved my deficiency. I also provide it to my children in the colder months.
9
Improved bone levels
2 people found this helpful
I was often tired and suffered from bone pain. After beginning treatment, my vitamin D levels improved significantly, and I feel much better now. Continuing this has turned my health around, proving beneficial for my overall well-being.
9
Boosted immunity effectively
2 people found this helpful
Vitamin D3 is vital for immunity and combating fatigue. It has significantly helped me tackle bone pain and improved my overall condition, especially during the pandemic. Consistent intake has enhanced my energy levels and resilience.
7
Active improvement
260 people found this helpful
I had a vitamin D deficiency, but after regular use, I feel more energised and my bone pain has improved significantly.
10
Pain alleviation
4 people found this helpful
After taking vitamin D for my previously severe deficiency, the joint pain and lethargy significantly reduced. I take it with Omega 3 for better absorption and have noticed profound improvements.
7.5
Excellent for bones
2 people found this helpful
This product is excellent for bone health. Many people suffer from vitamin D deficiency. The quantity is substantial, and the price is fantastic, plus it doesn't contain pork fat.
8
Vitamin D reduces fracture risk
We investigated the connection between vitamin D levels and the risk of new vertebral fractures in postmenopausal women who had undergone percutaneous vertebral augmentation. Through a retrospective case-control study involving patients aged 50 and older, we analyzed records to categorize participants into groups based on whether they experienced refractures and how serum levels of 25-hydroxyvitamin D (25[OH]D) influenced these outcomes.

Our findings revealed that low levels of serum 25(OH)D are linked to an increased risk of new vertebral fractures in these patients. What's noteworthy is that vitamin D plays a crucial role in maintaining bone health, and adequate levels can help reduce the likelihood of subsequent fractures after surgery. This underscores the potential importance of vitamin D supplementation for patients recovering from vertebral augmentation.

In conclusion, ensuring that patients receive appropriate vitamin D intake might be pivotal in preventing further bone pain and fractures following surgery. By addressing vitamin D deficiency, we could significantly improve bone health outcomes and enhance the quality of life for postmenopausal women recovering from vertebral fractures.
9
Vitamin D3 correction improves pain
We explored the impact of vitamin D3 levels on bone pain that patients experience after undergoing unicompartmental knee arthroplasty (UKA). The study involved 240 participants who were divided into three groups based on their vitamin D status—some received treatment before surgery, some after, and others had normal levels to begin with.

By administering vitamin D3 in three doses, we aimed to see if correcting deficiencies could alleviate post-operative bone pain. Throughout the recovery period, we measured pain levels using the visual analog scale at various intervals after the surgery.

Our findings clearly demonstrated that patients who corrected their vitamin D3 deficiency before surgery reported significantly better pain control after the operation compared to those who were treated afterwards or those who started with adequate levels. This highlights the importance of testing and addressing vitamin D status prior to orthopedic procedures, showing that it is a modifiable risk factor affecting recovery.
9
Effectiveness of calcitriol combination therapy
We conducted an insightful study to analyze how combining calcitriol, a form of vitamin D, with bisphosphonates affects bone pain in postmenopausal women suffering from osteoporosis. This quasi-experimental approach allowed us to compare two groups: one treated with calcitriol alone and the other with the combination treatment.

Our findings highlighted that adding bisphosphonates to calcitriol significantly alleviated bone pain among the participants. We observed improved evaluations of joint pain through the Visual Analogue Scale/Score, indicating that patients felt much better post-treatment. Furthermore, the combination therapy enhanced the patients' overall daily living capabilities and positively influenced bone metabolism and density.

Overall, our results suggest that calcitriol combined with bisphosphonates is effective in not just relieving pain but also supporting the long-term health of bones in postmenopausal women. This approach may pave the way for improved treatment strategies for osteoporosis in this demographic.

References

  1. Zhang SB, Yang J, Xu HW, Yi YY, Ren CX, et al. Association Between 25-hydroxyvitamin D Status and New Vertebral Fractures Post Percutaneous Vertebral Augmentation in Patients During Postmenopause: A Retrospective Case-control Study. Pain Physician. 2025;28:E31.
  2. Rajani AM, Mittal A, Kulkarni VU, Rajani KA, Rajani KA. Role of Pre-operative Correction of Vitamin D3 Deficiency in Controlling Post-operative Bone Pain after Unicompartmental Knee Arthroplasty. Malays Orthop J. 2024;18:7. 10.5704/MOJ.2411.002
  3. Han K, Wang X. Clinical efficacy and outcomes of calcitriol combined with bisphosphonates in the treatment of postmenopausal osteoporosis: A quasi-experimental study. Medicine (Baltimore). 2024;103:e40171. 10.1097/MD.0000000000040171
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