Overview
SCIENTIFIC SCORE
Moderately Effective
Based on 1 Research
8
USERS' SCORE
Good
Based on 11 Reviews
8
Supplement Facts
Serving Size: 1 Softgel
Amount Per Serving
%DV
Vitamin D3 (as Cholecalciferol) (from Lanolin)
50 mcg (2,000 IU)
250%
Top Medical Research Studies
8
We explored how a specific genetic variant associated with vitamin D might influence the occurrence of cold sores, also known as Herpes Simplex Labialis (HSL). Our research involved nearly 1,800 participants from the TwinsUK registry, with a focus on a group of 595 that completed both blood tests and questionnaires regarding their cold sore experiences.
From the participants surveyed, 235 reported having experienced cold sores at least once, and out of these, 160 indicated that they had recurrent episodes. While we investigated several genetic variants, including three commonly discussed in relation to cold sores, we found no significant links between these particular SNPs and the occurrence or recurrence of cold sores.
However, our analysis did reveal a noteworthy association with a genetic variation in the Vitamin D Receptor (VDR) gene. This variant was significantly correlated with both the history of cold sore outbreaks and their frequency. While this suggests a potential relationship between vitamin D-related genetics and cold sore experiences, it does not mean that vitamin D treatment has a proven direct effect on reducing these occurrences.
Overall, our findings provide an intriguing glimpse into the genetic factors that may play a role in cold sore reactivation, especially as it pertains to the VDR gene. Yet, since we didn't explore the direct effects of vitamin D supplementation, more research would be needed to conclusively determine how vitamin D treatment might influence cold sore frequency.
From the participants surveyed, 235 reported having experienced cold sores at least once, and out of these, 160 indicated that they had recurrent episodes. While we investigated several genetic variants, including three commonly discussed in relation to cold sores, we found no significant links between these particular SNPs and the occurrence or recurrence of cold sores.
However, our analysis did reveal a noteworthy association with a genetic variation in the Vitamin D Receptor (VDR) gene. This variant was significantly correlated with both the history of cold sore outbreaks and their frequency. While this suggests a potential relationship between vitamin D-related genetics and cold sore experiences, it does not mean that vitamin D treatment has a proven direct effect on reducing these occurrences.
Overall, our findings provide an intriguing glimpse into the genetic factors that may play a role in cold sore reactivation, especially as it pertains to the VDR gene. Yet, since we didn't explore the direct effects of vitamin D supplementation, more research would be needed to conclusively determine how vitamin D treatment might influence cold sore frequency.
Most Useful Reviews
9
Effective detox
15 people found this helpful
I take 2000 IU of vitamin D for health and detox. I prefer supplements since I avoid sunbathing. Since I began taking this, I haven't been catching colds, and I'm feeling much better overall.
10
Cold prevention
3 people found this helpful
I've been using this product for years, and it has kept me from catching colds for over 5 years, even during the COVID-19 pandemic! It’s essential for me, and the small capsules are easy to take.
9
Positive health impact
3 people found this helpful
Good composition of lanolin. No vitamin enhances health as much as vitamin D (D3). Research indicates vitamin D may help prevent colds or upper respiratory infections. Higher blood levels correlate with lower risks of conditions like heart attacks, breast cancer, and diabetes. I bought vitamin D3 for use during the pandemic, and the tablets are small and easy to swallow. It’s advisable to take them with fatty foods. My dosage is 2000 units.
Medical Researches
SCIENTIFIC SCORE
Moderately Effective
Based on 1 Research
8
- All Researches
8
We explored how a specific genetic variant associated with vitamin D might influence the occurrence of cold sores, also known as Herpes Simplex Labialis (HSL). Our research involved nearly 1,800 participants from the TwinsUK registry, with a focus on a group of 595 that completed both blood tests and questionnaires regarding their cold sore experiences.
From the participants surveyed, 235 reported having experienced cold sores at least once, and out of these, 160 indicated that they had recurrent episodes. While we investigated several genetic variants, including three commonly discussed in relation to cold sores, we found no significant links between these particular SNPs and the occurrence or recurrence of cold sores.
However, our analysis did reveal a noteworthy association with a genetic variation in the Vitamin D Receptor (VDR) gene. This variant was significantly correlated with both the history of cold sore outbreaks and their frequency. While this suggests a potential relationship between vitamin D-related genetics and cold sore experiences, it does not mean that vitamin D treatment has a proven direct effect on reducing these occurrences.
Overall, our findings provide an intriguing glimpse into the genetic factors that may play a role in cold sore reactivation, especially as it pertains to the VDR gene. Yet, since we didn't explore the direct effects of vitamin D supplementation, more research would be needed to conclusively determine how vitamin D treatment might influence cold sore frequency.
From the participants surveyed, 235 reported having experienced cold sores at least once, and out of these, 160 indicated that they had recurrent episodes. While we investigated several genetic variants, including three commonly discussed in relation to cold sores, we found no significant links between these particular SNPs and the occurrence or recurrence of cold sores.
However, our analysis did reveal a noteworthy association with a genetic variation in the Vitamin D Receptor (VDR) gene. This variant was significantly correlated with both the history of cold sore outbreaks and their frequency. While this suggests a potential relationship between vitamin D-related genetics and cold sore experiences, it does not mean that vitamin D treatment has a proven direct effect on reducing these occurrences.
Overall, our findings provide an intriguing glimpse into the genetic factors that may play a role in cold sore reactivation, especially as it pertains to the VDR gene. Yet, since we didn't explore the direct effects of vitamin D supplementation, more research would be needed to conclusively determine how vitamin D treatment might influence cold sore frequency.
User Reviews
USERS' SCORE
Good
Based on 11 Reviews
8
- All Reviews
- Positive Reviews
- Negative Reviews
9
Effective detox
15 people found this helpful
I take 2000 IU of vitamin D for health and detox. I prefer supplements since I avoid sunbathing. Since I began taking this, I haven't been catching colds, and I'm feeling much better overall.
10
Cold prevention
3 people found this helpful
I've been using this product for years, and it has kept me from catching colds for over 5 years, even during the COVID-19 pandemic! It’s essential for me, and the small capsules are easy to take.
9
Positive health impact
3 people found this helpful
Good composition of lanolin. No vitamin enhances health as much as vitamin D (D3). Research indicates vitamin D may help prevent colds or upper respiratory infections. Higher blood levels correlate with lower risks of conditions like heart attacks, breast cancer, and diabetes. I bought vitamin D3 for use during the pandemic, and the tablets are small and easy to swallow. It’s advisable to take them with fatty foods. My dosage is 2000 units.
9
Eliminated cold sores
2 people found this helpful
My family takes zinc picolinate, and since taking the complex I haven't had cold sores, nor have I experienced any night cramps, even after mild coronavirus.
7.5
Helps prevent infections
204 people found this helpful
Excellent! D3 from the top brand, Now Foods, is incredibly useful, particularly during cold seasons. It not only replenishes essential vitamins and minerals but also aids in combating viruses and bacteria.
Frequently Asked Questions
7.5
Improves health
90 people found this helpful
After taking this vitamin for a couple of weeks, I feel so much better. When I recently caught a cold, it was much milder than it would have been without this supplement.
7.5
Boosts immunity
141 people found this helpful
I really love this vitamin! The small capsules fit easily into a pill box. The dosage is perfect for me, and my immunity has increased; we’ve resisted colds well! I take it with Omega-3 and am very pleased with this company.
10
Cold prevention
3 people found this helpful
I've been using this product for years, and it has kept me from catching colds for over 5 years, even during the COVID-19 pandemic! It’s essential for me, and the small capsules are easy to take.
9
Effective detox
15 people found this helpful
I take 2000 IU of vitamin D for health and detox. I prefer supplements since I avoid sunbathing. Since I began taking this, I haven't been catching colds, and I'm feeling much better overall.
9
Eliminated cold sores
2 people found this helpful
My family takes zinc picolinate, and since taking the complex I haven't had cold sores, nor have I experienced any night cramps, even after mild coronavirus.
7.5
Reduced colds frequency
1 people found this helpful
I used to catch a cold almost every week, but since taking this supplement, I've experienced fewer colds. The pills are small and easy to swallow, which is a bonus. I switched to this 2000 IU dosage for safety.
7.5
Increases immunity
173 people found this helpful
I was looking for vitamin D in this dosage; it’s ideal for me. The price is very good, and the small capsules make them easy to swallow. Since starting treatment, my resistance to colds has improved significantly.
References
- Santamaria P, Bowyer RCE, Nibali L. Associations between host genetic variants and Herpes Simplex Labialis in the TwinsUK cohort. Arch Oral Biol. 2023;145:105587. doi:10.1016/j.archoralbio.2022.105587
