' 
SCIENTIFIC SCORE
Moderately Effective
Based on 1 Research
8
USERS' SCORE
Good
Based on 11 Reviews
8.7
Supplement Facts
Serving Size: 1 Softgel
Amount Per Serving
%DV
Vitamin D3 (as Cholecalciferol) (from Lanolin)
50 mcg (2,000 IU)
250%
Top Medical Research Studies
8
Genetic factors in cold sores
Associations between host genetic variants and Herpes Simplex Labialis in the TwinsUK cohort.
Genetic variant relevance acknowledged
We explored how a specific genetic variant associated with vitamin D might influence the occurrence of cold sores, also known as Herpes Simplex Labialis (HSL). Our research involved nearly 1,800 participants from the TwinsUK registry, with a focus on a group of 595 that completed both blood tests and questionnaires regarding their cold sore experiences.
From the participants surveyed, 235 reported having experienced cold sores at least once, and out of these, 160 indicated that they had recurrent episodes. While we investigated several genetic variants, including three commonly discussed in relation to cold sores, we found no significant links between these particular SNPs and the occurrence or recurrence of cold sores.
However, our analysis did reveal a noteworthy association with a genetic variation in the Vitamin D Receptor (VDR) gene. This variant was significantly correlated with both the history of cold sore outbreaks and their frequency. While this suggests a potential relationship between vitamin D-related genetics and cold sore experiences, it does not mean that vitamin D treatment has a proven direct effect on reducing these occurrences.
Overall, our findings provide an intriguing glimpse into the genetic factors that may play a role in cold sore reactivation, especially as it pertains to the VDR gene. Yet, since we didn't explore the direct effects of vitamin D supplementation, more research would be needed to conclusively determine how vitamin D treatment might influence cold sore frequency.
From the participants surveyed, 235 reported having experienced cold sores at least once, and out of these, 160 indicated that they had recurrent episodes. While we investigated several genetic variants, including three commonly discussed in relation to cold sores, we found no significant links between these particular SNPs and the occurrence or recurrence of cold sores.
However, our analysis did reveal a noteworthy association with a genetic variation in the Vitamin D Receptor (VDR) gene. This variant was significantly correlated with both the history of cold sore outbreaks and their frequency. While this suggests a potential relationship between vitamin D-related genetics and cold sore experiences, it does not mean that vitamin D treatment has a proven direct effect on reducing these occurrences.
Overall, our findings provide an intriguing glimpse into the genetic factors that may play a role in cold sore reactivation, especially as it pertains to the VDR gene. Yet, since we didn't explore the direct effects of vitamin D supplementation, more research would be needed to conclusively determine how vitamin D treatment might influence cold sore frequency.
Read More
Most Useful Reviews
9.5
Effective detox
I take 2000 IU of vitamin D for health and detox. I prefer supplements since I avoid sunbathing. Since I began taking this, I haven't been catching colds, and I'm feeling much better overall.
Read More
10
Cold prevention
I've been using this product for years, and it has kept me from catching colds for over 5 years, even during the COVID-19 pandemic! It’s essential for me, and the small capsules are easy to take.
Read More
8.3
Positive health impact
Good composition of lanolin. No vitamin enhances health as much as vitamin D (D3). Research indicates vitamin D may help prevent colds or upper respiratory infections. Higher blood levels correlate with lower risks of conditions like heart attacks, breast cancer, and diabetes. I bought vitamin D3 for use during the pandemic, and the tablets are small and easy to swallow. It’s advisable to take them with fatty foods. My dosage is 2000 units.
Read More
Medical Researches
SCIENTIFIC SCORE
Moderately Effective
Based on 1 Research
8
- All Researches
8
Genetic factors in cold sores
Associations between host genetic variants and Herpes Simplex Labialis in the TwinsUK cohort.
Genetic variant relevance acknowledged
We explored how a specific genetic variant associated with vitamin D might influence the occurrence of cold sores, also known as Herpes Simplex Labialis (HSL). Our research involved nearly 1,800 participants from the TwinsUK registry, with a focus on a group of 595 that completed both blood tests and questionnaires regarding their cold sore experiences.
From the participants surveyed, 235 reported having experienced cold sores at least once, and out of these, 160 indicated that they had recurrent episodes. While we investigated several genetic variants, including three commonly discussed in relation to cold sores, we found no significant links between these particular SNPs and the occurrence or recurrence of cold sores.
However, our analysis did reveal a noteworthy association with a genetic variation in the Vitamin D Receptor (VDR) gene. This variant was significantly correlated with both the history of cold sore outbreaks and their frequency. While this suggests a potential relationship between vitamin D-related genetics and cold sore experiences, it does not mean that vitamin D treatment has a proven direct effect on reducing these occurrences.
Overall, our findings provide an intriguing glimpse into the genetic factors that may play a role in cold sore reactivation, especially as it pertains to the VDR gene. Yet, since we didn't explore the direct effects of vitamin D supplementation, more research would be needed to conclusively determine how vitamin D treatment might influence cold sore frequency.
From the participants surveyed, 235 reported having experienced cold sores at least once, and out of these, 160 indicated that they had recurrent episodes. While we investigated several genetic variants, including three commonly discussed in relation to cold sores, we found no significant links between these particular SNPs and the occurrence or recurrence of cold sores.
However, our analysis did reveal a noteworthy association with a genetic variation in the Vitamin D Receptor (VDR) gene. This variant was significantly correlated with both the history of cold sore outbreaks and their frequency. While this suggests a potential relationship between vitamin D-related genetics and cold sore experiences, it does not mean that vitamin D treatment has a proven direct effect on reducing these occurrences.
Overall, our findings provide an intriguing glimpse into the genetic factors that may play a role in cold sore reactivation, especially as it pertains to the VDR gene. Yet, since we didn't explore the direct effects of vitamin D supplementation, more research would be needed to conclusively determine how vitamin D treatment might influence cold sore frequency.
Read More
User Reviews
USERS' SCORE
Good
Based on 11 Reviews
8.7
- All Reviews
- Positive Reviews
- Negative Reviews
9.5
Effective detox
I take 2000 IU of vitamin D for health and detox. I prefer supplements since I avoid sunbathing. Since I began taking this, I haven't been catching colds, and I'm feeling much better overall.
10
Cold prevention
I've been using this product for years, and it has kept me from catching colds for over 5 years, even during the COVID-19 pandemic! It’s essential for me, and the small capsules are easy to take.
8.3
Positive health impact
Good composition of lanolin. No vitamin enhances health as much as vitamin D (D3). Research indicates vitamin D may help prevent colds or upper respiratory infections. Higher blood levels correlate with lower risks of conditions like heart attacks, breast cancer, and diabetes. I bought vitamin D3 for use during the pandemic, and the tablets are small and easy to swallow. It’s advisable to take them with fatty foods. My dosage is 2000 units.
Read More
9.5
Eliminated cold sores
My family takes zinc picolinate, and since taking the complex I haven't had cold sores, nor have I experienced any night cramps, even after mild coronavirus.
8.8
Helps prevent infections
Excellent! D3 from the top brand, Now Foods, is incredibly useful, particularly during cold seasons. It not only replenishes essential vitamins and minerals but also aids in combating viruses and bacteria.
