We explored how zinc affects heart function in the context of obstructive sleep apnea (OSA), specifically focusing on cases of intermittent hypoxia (IH). In a detailed study using male rats, researchers set up different groups: a control group and one that underwent 10 weeks of exercise training. Half of the rats in both groups were exposed to IH conditions to simulate the effects of sleep apnea.
The results were eye-opening. Rats that experienced IH showed notable impairment in their heart's left ventricular function, characterized by reduced ejection fraction and increased inflammation. However, when treated with zinc, these negative effects were significantly countered. Notably, those who exercised and received zinc treatment displayed improved heart function and antioxidant capabilities compared to their counterparts that did not receive zinc.
On the flip side, exercise alone did not provide the same protective benefits when zinc was absent. The findings suggest that zinc is essential not only for the heart's protection against the damaging effects of IH but also enhances the benefits of physical exercise. This research indicates the importance of zinc in potentially managing heart health in individuals suffering from sleep apnea.
Read More
7
Magnesium's role in sleep apnea
Association between magnesium deficiency score and sleep quality in adults: A population-based cross-sectional study.
We aimed to uncover the relationship between magnesium levels and sleep quality, particularly focusing on sleep apnea. Our study analyzed data from a large group of adults aged 20 and older, using a well-structured method to assess magnesium levels and the prevalence of sleep issues.
We found a notable connection between lower magnesium levels, measured as the magnesium depletion score (MDS), and the likelihood of experiencing sleep apnea. Specifically, individuals with higher MDS levels were significantly more likely to report sleep apnea, showing over three times the odds compared to those with adequate magnesium levels.
Interestingly, our research did not link magnesium deficiency to other sleep problems like insomnia or restless legs syndrome, suggesting a more complex relationship with sleep apnea alone. Additionally, we noticed that older adults with depressive symptoms showed a tendency toward excessive sleep rather than insufficient sleep.
While our findings highlight the association between magnesium deficiency and sleep apnea, they also point towards the potential of adequate magnesium intake in reducing this risk. This emphasizes the importance of maintaining proper magnesium levels for better sleep quality, especially in those at higher risk for sleep apnea.
Read More
Most Useful Reviews
7.5
Improved sleep quality
29 people found this helpful
Gorgeous combination of zinc, magnesium, and vitamin B6! Optimum Nutrition's ZMA is essential for maximum recovery post-training. Zinc regulates cell growth and tissue repair, while magnesium maintains water-salt balance, generates energy, and normalises neuromuscular function. Exercising increases the need for these minerals, making ZMA a perfect supplement. Avoid taking ZMA with dairy or calcium supplements as it may reduce the anabolic effect and increase kidney stone risk. The effects are noticeably superior to other brands; I sleep like a baby on days I take it. My morning fatigue vanished with ZMA. I take 2 capsules before bedtime. Wishing you good health and a successful shopping experience on iHerb!
Read More
9
Enhanced muscle relaxation
22 people found this helpful
It certainly has an effect! I recommend it for serious sports enthusiasts. For casual exercisers, a standard multivitamin with B6, zinc, and magnesium might suffice. While I was quite active, I noticed significant improvements – my muscles were less tense, my sleep improved, and my digestion was smoother. Magnesium aids in bowel regularity, and these components also help in hormone regulation. For those who take a basic multivitamin, if you enjoy physical activity, I highly recommend trying ZMA for noticeable benefits.
Read More
7.5
Effective recovery aid
16 people found this helpful
Great ZMA complex! This combination of zinc, magnesium, and vitamin B6 is crucial for optimal recovery after workouts. Zinc supports cell growth and tissue repair, while magnesium aids in maintaining balance and energy production. The increase in mineral needs for active people makes ZMA ideal. Avoid dairy and calcium supplements with it, as this can diminish its anabolic effects and risk kidney stones. I find ZMA noticeably more effective than others; I sleep soundly when I take it. I now take 3 capsules before bed.
We explored how zinc affects heart function in the context of obstructive sleep apnea (OSA), specifically focusing on cases of intermittent hypoxia (IH). In a detailed study using male rats, researchers set up different groups: a control group and one that underwent 10 weeks of exercise training. Half of the rats in both groups were exposed to IH conditions to simulate the effects of sleep apnea.
The results were eye-opening. Rats that experienced IH showed notable impairment in their heart's left ventricular function, characterized by reduced ejection fraction and increased inflammation. However, when treated with zinc, these negative effects were significantly countered. Notably, those who exercised and received zinc treatment displayed improved heart function and antioxidant capabilities compared to their counterparts that did not receive zinc.
On the flip side, exercise alone did not provide the same protective benefits when zinc was absent. The findings suggest that zinc is essential not only for the heart's protection against the damaging effects of IH but also enhances the benefits of physical exercise. This research indicates the importance of zinc in potentially managing heart health in individuals suffering from sleep apnea.
Read More
7
Magnesium's role in sleep apnea
Association between magnesium deficiency score and sleep quality in adults: A population-based cross-sectional study.
We aimed to uncover the relationship between magnesium levels and sleep quality, particularly focusing on sleep apnea. Our study analyzed data from a large group of adults aged 20 and older, using a well-structured method to assess magnesium levels and the prevalence of sleep issues.
We found a notable connection between lower magnesium levels, measured as the magnesium depletion score (MDS), and the likelihood of experiencing sleep apnea. Specifically, individuals with higher MDS levels were significantly more likely to report sleep apnea, showing over three times the odds compared to those with adequate magnesium levels.
Interestingly, our research did not link magnesium deficiency to other sleep problems like insomnia or restless legs syndrome, suggesting a more complex relationship with sleep apnea alone. Additionally, we noticed that older adults with depressive symptoms showed a tendency toward excessive sleep rather than insufficient sleep.
While our findings highlight the association between magnesium deficiency and sleep apnea, they also point towards the potential of adequate magnesium intake in reducing this risk. This emphasizes the importance of maintaining proper magnesium levels for better sleep quality, especially in those at higher risk for sleep apnea.
Read More
User Reviews
USERS' SCORE
Moderately Good
Based on 66 Reviews
7.6
All Reviews
Positive Reviews
Negative Reviews
7.5
Improved sleep quality
29 people found this helpful
Gorgeous combination of zinc, magnesium, and vitamin B6! Optimum Nutrition's ZMA is essential for maximum recovery post-training. Zinc regulates cell growth and tissue repair, while magnesium maintains water-salt balance, generates energy, and normalises neuromuscular function. Exercising increases the need for these minerals, making ZMA a perfect supplement. Avoid taking ZMA with dairy or calcium supplements as it may reduce the anabolic effect and increase kidney stone risk. The effects are noticeably superior to other brands; I sleep like a baby on days I take it. My morning fatigue vanished with ZMA. I take 2 capsules before bedtime. Wishing you good health and a successful shopping experience on iHerb!
Read More
9
Enhanced muscle relaxation
22 people found this helpful
It certainly has an effect! I recommend it for serious sports enthusiasts. For casual exercisers, a standard multivitamin with B6, zinc, and magnesium might suffice. While I was quite active, I noticed significant improvements – my muscles were less tense, my sleep improved, and my digestion was smoother. Magnesium aids in bowel regularity, and these components also help in hormone regulation. For those who take a basic multivitamin, if you enjoy physical activity, I highly recommend trying ZMA for noticeable benefits.
Read More
7.5
Effective recovery aid
16 people found this helpful
Great ZMA complex! This combination of zinc, magnesium, and vitamin B6 is crucial for optimal recovery after workouts. Zinc supports cell growth and tissue repair, while magnesium aids in maintaining balance and energy production. The increase in mineral needs for active people makes ZMA ideal. Avoid dairy and calcium supplements with it, as this can diminish its anabolic effects and risk kidney stones. I find ZMA noticeably more effective than others; I sleep soundly when I take it. I now take 3 capsules before bed.
Read More
9
Quick effectiveness
8 people found this helpful
Great product! I hesitated to buy it but am now glad I did. This dietary supplement truly works. Although I didn’t take it on an empty stomach, I felt results in just 10-15 minutes. I sleep very well now, waking up refreshed without the heaviness typical of sleeping pills. I definitely recommend it for anyone struggling with sleep.
Read More
7.5
Promotes deep sleep
8 people found this helpful
Excellent complex! ZMA is vital for optimal recovery after intense training. It combines zinc, magnesium, and vitamin B6, important for cell repair and immune health. Magnesium aids in water-salt balance and energy, which increases with exercise. ZMA should not be taken with dairy or calcium, as this can reduce its effects and risk kidney stones. I find the effects much stronger than other products; I sleep deeply when I use it. It significantly helps my morning fatigue; I take 3 capsules before bed.
Sleep apnea is a common and potentially serious sleep disorder characterized by irregular breathing patterns during sleep. Individuals with sleep apnea experience episodes of disrupted or paused breathing, which can occur multiple times throughout the night. These interruptions can last a few seconds to several minutes and often lead to fragmented sleep, which may result in excessive daytime sleepiness, irritability, and difficulty concentrating. The condition can be broadly classified into two main types: obstructive sleep apnea (OSA), caused by a blockage of the upper airway, and central sleep apnea (CSA), which occurs when the brain fails to send the proper signals to the muscles that control breathing.
The diagnosis of sleep apnea typically involves a sleep study, either conducted in a sleep clinic or at home using portable monitoring devices. Treatment options vary depending on the severity of the condition but may include lifestyle changes, the use of continuous positive airway pressure (CPAP) machines, oral appliances, or even surgery in some cases. If left untreated, sleep apnea can lead to various health complications, including cardiovascular issues, metabolic disorders, and impaired cognitive function, making it essential to consult a healthcare professional if you suspect you or someone you know may be affected by this disorder.
Zinc Magnesium Aspartate, often referred to as ZMA, is a dietary supplement that combines three key ingredients: zinc, magnesium, and aspartic acid. This supplement is primarily marketed towards athletes and those looking to enhance their physical performance, as the components of ZMA are believed to support muscle recovery, improve sleep quality, and potentially boost testosterone levels. Zinc plays a crucial role in hormone production and immune function, while magnesium is essential for muscle relaxation and energy production. Aspartic acid, an amino acid, is thought to aid in the absorption of these minerals and may also support testosterone synthesis.
Many users report increased energy levels, improved sleep, and enhanced recovery from workouts when taking ZMA, making it a popular choice among fitness enthusiasts. However, scientific research on the effectiveness of ZMA is mixed. While some studies suggest benefits in testosterone levels and overall athletic performance, others show little to no significant impact. It's important to note that, like any supplement, individual responses can vary widely. If you're considering adding Zinc Magnesium Aspartate to your routine, it’s advisable to consult with a healthcare professional to ensure it's appropriate for your specific health needs and fitness goals.
Based on user reviews, the timeframe for experiencing the effects of this supplement, particularly in relation to sleep, can vary significantly among individuals. Some users report feeling improvements almost immediately. For instance, one individual noted results within just 10-15 minutes of taking the product, emphasizing how it helped them sleep better without the heaviness often associated with sleeping pills Read Review. Another reviewer mentioned they noticed significant changes in their sleep quality after only two doses Read Review.
Conversely, other users indicated that it might take a bit longer to experience the full benefits. For example, one review mentioned that after about three months of continuous use, they observed a noticeable difference in sleep quality and overall well-being Read Review. Overall, it appears that while some users may see changes within minutes to days, others might require several weeks for the supplement to yield significant results. It's essential to consider individual responses and consult with a healthcare professional for personalized advice.
The relationship between magnesium and sleep apnea is clearly outlined in recent research, which revealed that lower magnesium levels are significantly associated with an increased likelihood of experiencing sleep apnea. In a study analyzing a large group of adults, participants with higher magnesium depletion scores were found to be over three times more likely to report sleep apnea compared to those with adequate magnesium levels. This suggests that maintaining proper magnesium levels could be crucial for individuals at risk of sleep apnea, highlighting its potential role in improving sleep quality for these patients [1].
On the other hand, zinc's protective effects in the context of sleep apnea have also been investigated. A study conducted on male rats demonstrated that zinc treatment mitigated the detrimental impacts of intermittent hypoxia, a condition simulating sleep apnea, on heart function. Rats receiving zinc exhibited improved heart function and reduced inflammation, suggesting that zinc may play an essential role in managing cardiovascular health in those suffering from sleep apnea [2]. While both supplements show promise in addressing aspects of sleep apnea, further research is warranted to fully understand their effectiveness and potential as treatment options.
Based on user reviews, many individuals have reported significant improvements in their sleep quality after using the ZMA supplement. Users like those who noted effects within 10-15 minutes Read Review mentioned waking up refreshed and avoiding the grogginess often associated with other sleep aids. A common sentiment among reviewers is the ability to achieve deep, uninterrupted sleep, making it particularly appealing for those recovering from intense workouts Read Review. One user even highlighted how their sleep disturbances that had persisted for years resolved after just two doses Read Review.
Aside from enhancing sleep quality, many reviewers noted that their overall energy levels have improved as well. For example, users have reported feeling more energetic and less fatigued throughout the day after starting this supplement Read Review. Additionally, some users mentioned they achieved better muscle recovery and felt calmer, linking these benefits to the supplement's ability to promote restful sleep Read Review. Although individual results can vary, many users have expressed satisfaction with their experiences, indicating a strong tendency for ZMA to contribute positively to sleep and recovery.
Based on user reviews, many individuals have reported positive experiences when combining ZMA with other supplements for managing their sleep quality and overall recovery. Notably, one user mentioned that combining ZMA with Gold Standard 100% Casein significantly maximizes the benefits, enhancing their recovery after workouts while also improving sleep through the night without interruptions Read Review. This suggests that pairing ZMA with certain protein supplements may lead to enhanced results, especially for those who are physically active.
However, some reviews caution against specific combinations. Users have advised against taking ZMA with dairy or calcium supplements, as these could potentially diminish the anabolic effects of ZMA and increase the risk of kidney stones Read Review. Overall, while many find the integration of ZMA with certain supplements beneficial, it’s crucial for users to consider their unique health needs and consult a healthcare professional for personalized advice regarding supplementation.
Users widely report effective dosages for Zinc Magnesium Aspartate (ZMA) when it comes to improving sleep quality. Many reviewers suggest that taking 2 to 3 capsules before bedtime enhances their ability to fall asleep and stay asleep through the night. A user noted that they took 3 capsules an hour before bed, leading to a calm sleep and waking up refreshed, while another user confirmed that they felt significant sleep improvements with 3 tablets before sleep Read Review. Additionally, one review indicates that the product is more effective for men's dosages, recommending three pills specifically for men, while two capsules are recommended for women Read Review.
Overall, users seem to find that consistent nightly doses of ZMA lead to improved sleep quality, recovery after workouts, and reduced morning fatigue. This blend of zinc, magnesium, and vitamin B6 is widely viewed as a crucial supplement, especially for those engaged in physical activity or suffering from sleep disturbances. Many expressed their satisfaction with the results, feeling more energized during the day after using ZMA Read Review.
9
Quick effectiveness
8 people found this helpful
Great product! I hesitated to buy it but am now glad I did. This dietary supplement truly works. Although I didn’t take it on an empty stomach, I felt results in just 10-15 minutes. I sleep very well now, waking up refreshed without the heaviness typical of sleeping pills. I definitely recommend it for anyone struggling with sleep.
9
Solved sleep issues
1 people found this helpful
Prior to taking this supplement after intense training, I struggled with sleep issues. It became evident that I lacked zinc or magnesium. After starting this combined complex, I resolved my sleep problems in just two doses, and they haven’t returned in a year.
9
Increased energy
1 people found this helpful
It helps me achieve a calm sleep, leading to more energy at the gym and fewer muscle spasms. Taking these caps an hour before sleep, with plenty of liquid, makes me very sleepy within 30 minutes. I wake up relaxed and not groggy. After about 3 months of use, I've noticed a leaner appearance and weight loss.
9
Recovery aid
1 people found this helpful
ZMA has been superb for me over the years. I use it to recover after hard workouts and to help me sleep through the night without interruptions. Combining it with Gold Standard 100% Casein maximises its benefits.
9
Sustained energy boost
5 people found this helpful
This product is simply amazing! I often work late, and it really helps me get quality sleep even after long nights. I wake up alert without feeling tired. It has definitely improved my energy levels throughout the day! I highly recommend this product for anyone needing sustained energy.
9
Quality sleep
1 people found this helpful
I sleep like a baby. This product helps me achieve quality sleep, calms me, and allows me to stay asleep without waking groggy in the mornings. Absolutely love it!
7.5
Improved sleep quality
29 people found this helpful
Gorgeous combination of zinc, magnesium, and vitamin B6! Optimum Nutrition's ZMA is essential for maximum recovery post-training. Zinc regulates cell growth and tissue repair, while magnesium maintains water-salt balance, generates energy, and normalises neuromuscular function. Exercising increases the need for these minerals, making ZMA a perfect supplement. Avoid taking ZMA with dairy or calcium supplements as it may reduce the anabolic effect and increase kidney stone risk. The effects are noticeably superior to other brands; I sleep like a baby on days I take it. My morning fatigue vanished with ZMA. I take 2 capsules before bedtime. Wishing you good health and a successful shopping experience on iHerb!
9
Quality of sleep
1 people found this helpful
Excellent! I’ve tried it multiple times, and taking 3 tablets before bed significantly enhances my sleep quality.
9
Excellent for insomnia
2 people found this helpful
The packaging and quality of this product are impressive. I'm sure it works well for those who go to the gym or suffer from insomnia, as it helps one achieve a deep sleep. The dosage is clear: three pills for men and two for women, taken two hours before bed.
7.5
Effective recovery aid
16 people found this helpful
Great ZMA complex! This combination of zinc, magnesium, and vitamin B6 is crucial for optimal recovery after workouts. Zinc supports cell growth and tissue repair, while magnesium aids in maintaining balance and energy production. The increase in mineral needs for active people makes ZMA ideal. Avoid dairy and calcium supplements with it, as this can diminish its anabolic effects and risk kidney stones. I find ZMA noticeably more effective than others; I sleep soundly when I take it. I now take 3 capsules before bed.
7
Magnesium's role in sleep apnea
Association between magnesium deficiency score and sleep quality in adults: A population-based cross-sectional study.
We aimed to uncover the relationship between magnesium levels and sleep quality, particularly focusing on sleep apnea. Our study analyzed data from a large group of adults aged 20 and older, using a well-structured method to assess magnesium levels and the prevalence of sleep issues.
We found a notable connection between lower magnesium levels, measured as the magnesium depletion score (MDS), and the likelihood of experiencing sleep apnea. Specifically, individuals with higher MDS levels were significantly more likely to report sleep apnea, showing over three times the odds compared to those with adequate magnesium levels.
Interestingly, our research did not link magnesium deficiency to other sleep problems like insomnia or restless legs syndrome, suggesting a more complex relationship with sleep apnea alone. Additionally, we noticed that older adults with depressive symptoms showed a tendency toward excessive sleep rather than insufficient sleep.
While our findings highlight the association between magnesium deficiency and sleep apnea, they also point towards the potential of adequate magnesium intake in reducing this risk. This emphasizes the importance of maintaining proper magnesium levels for better sleep quality, especially in those at higher risk for sleep apnea.
9
Zinc protects heart function in OSA
Zinc Is Indispensable in Exercise-Induced Cardioprotection against Intermittent Hypoxia-Induced Left Ventricular Function Impairment in Rats.
We explored how zinc affects heart function in the context of obstructive sleep apnea (OSA), specifically focusing on cases of intermittent hypoxia (IH). In a detailed study using male rats, researchers set up different groups: a control group and one that underwent 10 weeks of exercise training. Half of the rats in both groups were exposed to IH conditions to simulate the effects of sleep apnea.
The results were eye-opening. Rats that experienced IH showed notable impairment in their heart's left ventricular function, characterized by reduced ejection fraction and increased inflammation. However, when treated with zinc, these negative effects were significantly countered. Notably, those who exercised and received zinc treatment displayed improved heart function and antioxidant capabilities compared to their counterparts that did not receive zinc.
On the flip side, exercise alone did not provide the same protective benefits when zinc was absent. The findings suggest that zinc is essential not only for the heart's protection against the damaging effects of IH but also enhances the benefits of physical exercise. This research indicates the importance of zinc in potentially managing heart health in individuals suffering from sleep apnea.
References
Luo X, Tang M, Wei X, Peng Y. Association between magnesium deficiency score and sleep quality in adults: A population-based cross-sectional study. J Affect Disord. 2024;358:105. doi:10.1016/j.jad.2024.05.002
Chen TI, Chen MY. Zinc Is Indispensable in Exercise-Induced Cardioprotection against Intermittent Hypoxia-Induced Left Ventricular Function Impairment in Rats. PLoS One. 2016;11:e0168600. doi:10.1371/journal.pone.0168600