Last update
3/17/2026

Overview

SCIENTIFIC SCORE
Questionable
Based on 1 Research
5
USERS' SCORE
Good
Based on 6 Reviews
8.3
Supplement Facts
Serving Size:  2 Capsules
Serving Per Container: 120
Amount Per Serving
%DV
L-Glutamine
1 g
*
📅 Last updated:

Top Medical Research Studies

5
Investigating L-glutamine in CFS
We explored how natural anti-inflammatory and antioxidant substances like L-glutamine could affect chronic fatigue syndrome (CFS) in patients. Over a 10-14 month period, we measured immune responses and overall health in 41 CFS patients before and after treatment.

Our findings indicated that improving gut health through these substances might lead to better clinical outcomes. While the study emphasizes targeted treatments for leaky gut in CFS, we found that it’s a promising area for future research rather than a definitive cure.
Read More

Most Useful Reviews

9
Enhanced recovery
2 people found this helpful
Glutamine has greatly improved my recovery after workouts and helped with chronic fatigue syndrome. I give my 5-year-old child 100 to 150 mg daily, and we both feel a positive effect. Combining it with Lysine intensifies its benefits.
Read More
9
Muscle repair support
Optimum Nutrition Glutamine supports muscle recovery, immune health, and gut health. It’s ideal for anyone, including those like me managing chronic fatigue syndrome, seeking to reduce muscle soreness after intensive workouts.
Read More
7.5
Fatigue relief
This supplement helps relieve my tiredness thanks to chronic fatigue syndrome. It has been beneficial after my workouts.
Read More

Medical Researches

SCIENTIFIC SCORE
Questionable
Based on 1 Research
5
  • All Researches
5
Investigating L-glutamine in CFS
We explored how natural anti-inflammatory and antioxidant substances like L-glutamine could affect chronic fatigue syndrome (CFS) in patients. Over a 10-14 month period, we measured immune responses and overall health in 41 CFS patients before and after treatment.

Our findings indicated that improving gut health through these substances might lead to better clinical outcomes. While the study emphasizes targeted treatments for leaky gut in CFS, we found that it’s a promising area for future research rather than a definitive cure.
Read More

User Reviews

USERS' SCORE
Good
Based on 6 Reviews
8.3
  • All Reviews
  • Positive Reviews
  • Negative Reviews
9
Enhanced recovery
2 people found this helpful
Glutamine has greatly improved my recovery after workouts and helped with chronic fatigue syndrome. I give my 5-year-old child 100 to 150 mg daily, and we both feel a positive effect. Combining it with Lysine intensifies its benefits.
Read More
9
Muscle repair support
Optimum Nutrition Glutamine supports muscle recovery, immune health, and gut health. It’s ideal for anyone, including those like me managing chronic fatigue syndrome, seeking to reduce muscle soreness after intensive workouts.
Read More
7.5
Fatigue relief
This supplement helps relieve my tiredness thanks to chronic fatigue syndrome. It has been beneficial after my workouts.
Read More
7.5
Helps recovery
I take it after training. Continuing with it helps me recover from fatigue, making it a very good product for managing my chronic fatigue syndrome.
Read More
7.5
Improved gut health
5 people found this helpful
I took this vitamin for my sister, who suffers from intestinal issues, allergic rashes, and chronic fatigue syndrome. She noticed an improvement. Glutamine is crucial for various bodily functions, particularly in normalising the intestines.
Read More

Frequently Asked Questions

7.5
Helps recovery
I take it after training. Continuing with it helps me recover from fatigue, making it a very good product for managing my chronic fatigue syndrome.
9
Enhanced recovery
2 people found this helpful
Glutamine has greatly improved my recovery after workouts and helped with chronic fatigue syndrome. I give my 5-year-old child 100 to 150 mg daily, and we both feel a positive effect. Combining it with Lysine intensifies its benefits.
9
Muscle repair support
Optimum Nutrition Glutamine supports muscle recovery, immune health, and gut health. It’s ideal for anyone, including those like me managing chronic fatigue syndrome, seeking to reduce muscle soreness after intensive workouts.
5
Investigating L-glutamine in CFS
We explored how natural anti-inflammatory and antioxidant substances like L-glutamine could affect chronic fatigue syndrome (CFS) in patients. Over a 10-14 month period, we measured immune responses and overall health in 41 CFS patients before and after treatment.

Our findings indicated that improving gut health through these substances might lead to better clinical outcomes. While the study emphasizes targeted treatments for leaky gut in CFS, we found that it’s a promising area for future research rather than a definitive cure.

References

  1. Maes M, Leunis JC. Normalization of leaky gut in chronic fatigue syndrome (CFS) is accompanied by a clinical improvement: effects of age, duration of illness and the translocation of LPS from gram-negative bacteria. Neuro Endocrinol Lett. 2008;29:902. PubMed
Data last updated:
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