Overview

SCIENTIFIC SCORE
Moderately Effective
Based on 1 Research
8
USERS' SCORE
Good
Based on 34 Reviews
8
Supplement Facts
Serving Size:  2 Tablets
Amount Per Serving
%DV
Calories
10
 
Total Carbohydrate
2 g
1%**
Vitamin C (as Ascorbic Acid)
60 mg
67%
Manganese (as Manganese Sulfate)
2 mg
87%
Sodium
35 mg
2%
Glucosamine HCl
1,500 mg (1.5 g)
***
Joint Shield™ 5-Loxin Advanced® Boswellia serrata Extract (resin)
100 mg
***
Chondroitin/MSM ComplexChondroitin Sulfate, Methylsulfonylmethane (MSM), Collagen (Hydrolyzed Gelatin), Boswellia serrata (resin), Boron (as Bororganic Glycine), Hyaluronic Acid
1,103 mg (1.1 g)
***

Top Medical Research Studies

8
Glucosamine and exercise enhance arthritis treatment
We sought to determine whether a combination of a nutrition supplement, including glucosamine and chondroitin, along with supervised exercise, is more effective for knee osteoarthritis than exercise alone.

In a six-month double-blinded trial involving 65 participants, those who took the supplement experienced significant improvements in pain and stiffness earlier compared to those receiving a placebo.

This suggests that using glucosamine chondroitin supplementation along with exercise could be a more efficient treatment strategy for arthritis in the knee.
Read More

Most Useful Reviews

7.5
Pain relief effective
8 people found this helpful
I regularly purchase this medication for my mother, aged 69, who has suffered from arthritis for over 15 years. She is very pleased with its effects, which surpass those of sulfasalazine, with fewer side effects. She takes it for two months, then has a break for two months while continuing Boswellia. After her first dose, she felt relief by the seventh day. Now, her hand joints are less inflamed and more comfortable.
Read More
7.5
Reduced joint pain
6 people found this helpful
I purchased this for my mother, who began experiencing arthritis. After a week of use, she noticed less twisting of her joints at night and a significant decrease in pain. She also drinks collagen periodically. I recommend this complex for those with joint issues or as prevention.
Read More
9
Improved joint health
5 people found this helpful
I bought this nutritional supplement for my mother to support her arthritic joints. After searching for this specific triple-strength formula, I was pleased with the price. It arrived quickly and in perfect condition. Mom is very happy with the supplement, and we've observed that her joints no longer ache with changes in the weather, and her overall condition has improved. I will order this supplement again.
Read More

Medical Researches

SCIENTIFIC SCORE
Moderately Effective
Based on 1 Research
8
  • All Researches
8
Glucosamine and exercise enhance arthritis treatment
We sought to determine whether a combination of a nutrition supplement, including glucosamine and chondroitin, along with supervised exercise, is more effective for knee osteoarthritis than exercise alone.

In a six-month double-blinded trial involving 65 participants, those who took the supplement experienced significant improvements in pain and stiffness earlier compared to those receiving a placebo.

This suggests that using glucosamine chondroitin supplementation along with exercise could be a more efficient treatment strategy for arthritis in the knee.
Read More

User Reviews

USERS' SCORE
Good
Based on 34 Reviews
8
  • All Reviews
  • Positive Reviews
  • Negative Reviews
7.5
Pain relief effective
8 people found this helpful
I regularly purchase this medication for my mother, aged 69, who has suffered from arthritis for over 15 years. She is very pleased with its effects, which surpass those of sulfasalazine, with fewer side effects. She takes it for two months, then has a break for two months while continuing Boswellia. After her first dose, she felt relief by the seventh day. Now, her hand joints are less inflamed and more comfortable.
Read More
7.5
Reduced joint pain
6 people found this helpful
I purchased this for my mother, who began experiencing arthritis. After a week of use, she noticed less twisting of her joints at night and a significant decrease in pain. She also drinks collagen periodically. I recommend this complex for those with joint issues or as prevention.
Read More
9
Improved joint health
5 people found this helpful
I bought this nutritional supplement for my mother to support her arthritic joints. After searching for this specific triple-strength formula, I was pleased with the price. It arrived quickly and in perfect condition. Mom is very happy with the supplement, and we've observed that her joints no longer ache with changes in the weather, and her overall condition has improved. I will order this supplement again.
Read More
10
Zero pain relief
3 people found this helpful
Works!!! I am impressed by how well this product works. I suffer from osteoarthritis in both thumbs, which has worsened recently. After starting this product, I am happy to report that I experience zero pain. 99% of the pain is gone now.
Read More
7.5
Constant pain reduction
2 people found this helpful
I have taken Osteo Bi-Flex alongside type 2 collagen for six months. As I suffer from arthritis, these products have greatly reduced my chronic pain in my hands and knees. While the condition remains, I feel I can support my joints effectively now.
Read More

Frequently Asked Questions

7.5
Pain relief effective
8 people found this helpful
I regularly purchase this medication for my mother, aged 69, who has suffered from arthritis for over 15 years. She is very pleased with its effects, which surpass those of sulfasalazine, with fewer side effects. She takes it for two months, then has a break for two months while continuing Boswellia. After her first dose, she felt relief by the seventh day. Now, her hand joints are less inflamed and more comfortable.
9
Effective pain relief
1 people found this helpful
I introduced this product to my 66-year-old father, who suffered greatly from knee pain due to arthritis. After just seven days, his symptoms vanished, and he no longer needed anti-inflammatories. He now takes this medication continuously and finds it very effective, especially compared to other options available in our local pharmacies.
9
Effective for arthritis
I have arthritis in my knee, and it works extremely well. I've been using it for three months and have no intention of stopping.
7.5
Constant pain reduction
2 people found this helpful
I have taken Osteo Bi-Flex alongside type 2 collagen for six months. As I suffer from arthritis, these products have greatly reduced my chronic pain in my hands and knees. While the condition remains, I feel I can support my joints effectively now.
6
Relief from pain
3 people found this helpful
I've used this product for three years, having first obtained a sample. As a fitness enthusiast, I experienced joint issues and was diagnosed with arthrosis. My rheumatologist advised an increased dosage due to my physical activities. This supplement has provided significant support for my arthritis and arthrosis in my knees and hips.
7.5
Reduced joint pain
6 people found this helpful
I purchased this for my mother, who began experiencing arthritis. After a week of use, she noticed less twisting of her joints at night and a significant decrease in pain. She also drinks collagen periodically. I recommend this complex for those with joint issues or as prevention.
9
Improved joint health
5 people found this helpful
I bought this nutritional supplement for my mother to support her arthritic joints. After searching for this specific triple-strength formula, I was pleased with the price. It arrived quickly and in perfect condition. Mom is very happy with the supplement, and we've observed that her joints no longer ache with changes in the weather, and her overall condition has improved. I will order this supplement again.
7
Noticeable improvement
I ordered this for my father with arthritis and joint inflammation. He noticed an improvement mid-course, especially taking it alongside omega and D3. I think it's wise for him to take it biannually.
9
Significant improvement
1 people found this helpful
Suffering from arthritis made it difficult to walk and caused severe back pain. After using Osteo Bi-Flex for a few weeks, I found I was walking much better, and my back pain subsided significantly. The improvement amazed me, enabling me to go on long walks again, with less reliance on my cane. It's also affordable for my fixed income.
8
Glucosamine and exercise enhance arthritis treatment
We sought to determine whether a combination of a nutrition supplement, including glucosamine and chondroitin, along with supervised exercise, is more effective for knee osteoarthritis than exercise alone.

In a six-month double-blinded trial involving 65 participants, those who took the supplement experienced significant improvements in pain and stiffness earlier compared to those receiving a placebo.

This suggests that using glucosamine chondroitin supplementation along with exercise could be a more efficient treatment strategy for arthritis in the knee.

References

  1. Liu W, Yu Y, Zhang Z, Li Z, Wu Y, et al. Nutrition supplementation combined with exercise versus exercise alone in treating knee osteoarthritis: a double-blinded, randomised, placebo-controlled trial. Age Ageing. 2025;54. doi:10.1093/ageing/afaf010
image