Glucosamine and exercise enhance arthritis treatment
Nutrition supplementation combined with exercise versus exercise alone in treating knee osteoarthritis: a double-blinded, randomised, placebo-controlled trial.
We sought to determine whether a combination of a nutrition supplement, including glucosamine and chondroitin, along with supervised exercise, is more effective for knee osteoarthritis than exercise alone.
In a six-month double-blinded trial involving 65 participants, those who took the supplement experienced significant improvements in pain and stiffness earlier compared to those receiving a placebo.
This suggests that using glucosamine chondroitin supplementation along with exercise could be a more efficient treatment strategy for arthritis in the knee.
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Most Useful Reviews
7.5
Pain relief effective
8 people found this helpful
I regularly purchase this medication for my mother, aged 69, who has suffered from arthritis for over 15 years. She is very pleased with its effects, which surpass those of sulfasalazine, with fewer side effects. She takes it for two months, then has a break for two months while continuing Boswellia. After her first dose, she felt relief by the seventh day. Now, her hand joints are less inflamed and more comfortable.
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7.5
Reduced joint pain
6 people found this helpful
I purchased this for my mother, who began experiencing arthritis. After a week of use, she noticed less twisting of her joints at night and a significant decrease in pain. She also drinks collagen periodically. I recommend this complex for those with joint issues or as prevention.
Read More
9
Improved joint health
5 people found this helpful
I bought this nutritional supplement for my mother to support her arthritic joints. After searching for this specific triple-strength formula, I was pleased with the price. It arrived quickly and in perfect condition. Mom is very happy with the supplement, and we've observed that her joints no longer ache with changes in the weather, and her overall condition has improved. I will order this supplement again.
Glucosamine and exercise enhance arthritis treatment
Nutrition supplementation combined with exercise versus exercise alone in treating knee osteoarthritis: a double-blinded, randomised, placebo-controlled trial.
We sought to determine whether a combination of a nutrition supplement, including glucosamine and chondroitin, along with supervised exercise, is more effective for knee osteoarthritis than exercise alone.
In a six-month double-blinded trial involving 65 participants, those who took the supplement experienced significant improvements in pain and stiffness earlier compared to those receiving a placebo.
This suggests that using glucosamine chondroitin supplementation along with exercise could be a more efficient treatment strategy for arthritis in the knee.
Read More
User Reviews
USERS' SCORE
Good
Based on 34 Reviews
8
All Reviews
Positive Reviews
Negative Reviews
7.5
Pain relief effective
8 people found this helpful
I regularly purchase this medication for my mother, aged 69, who has suffered from arthritis for over 15 years. She is very pleased with its effects, which surpass those of sulfasalazine, with fewer side effects. She takes it for two months, then has a break for two months while continuing Boswellia. After her first dose, she felt relief by the seventh day. Now, her hand joints are less inflamed and more comfortable.
Read More
7.5
Reduced joint pain
6 people found this helpful
I purchased this for my mother, who began experiencing arthritis. After a week of use, she noticed less twisting of her joints at night and a significant decrease in pain. She also drinks collagen periodically. I recommend this complex for those with joint issues or as prevention.
Read More
9
Improved joint health
5 people found this helpful
I bought this nutritional supplement for my mother to support her arthritic joints. After searching for this specific triple-strength formula, I was pleased with the price. It arrived quickly and in perfect condition. Mom is very happy with the supplement, and we've observed that her joints no longer ache with changes in the weather, and her overall condition has improved. I will order this supplement again.
Read More
10
Zero pain relief
3 people found this helpful
Works!!! I am impressed by how well this product works. I suffer from osteoarthritis in both thumbs, which has worsened recently. After starting this product, I am happy to report that I experience zero pain. 99% of the pain is gone now.
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7.5
Constant pain reduction
2 people found this helpful
I have taken Osteo Bi-Flex alongside type 2 collagen for six months. As I suffer from arthritis, these products have greatly reduced my chronic pain in my hands and knees. While the condition remains, I feel I can support my joints effectively now.
Arthritis is a general term that refers to inflammation of the joints, which can lead to pain, stiffness, and swelling. It encompasses over 100 different types, with osteoarthritis and rheumatoid arthritis being the most common. Osteoarthritis, often associated with aging, occurs when the cartilage that cushions the joints wears down over time. In contrast, rheumatoid arthritis is an autoimmune disorder where the body's immune system mistakenly attacks the joints, leading to chronic inflammation and potential disability if left untreated.
Symptoms of arthritis can vary widely depending on the type but typically include joint pain, swelling, reduced range of motion, and sometimes fatigue. Diagnosis usually involves a combination of physical exams, imaging tests, and blood tests. While there is currently no cure for arthritis, various treatments ranging from lifestyle modifications, physical therapy, and medications can help manage symptoms and improve quality of life. For those affected, seeking early diagnosis and intervention is crucial for slowing disease progression and preserving joint function.
Glucosamine Chondroitin formulas are dietary supplements commonly used to support joint health and alleviate symptoms associated with osteoarthritis. These formulas typically contain glucosamine, a naturally occurring compound in the body that contributes to the formation and repair of cartilage, and chondroitin sulfate, which helps cartilage retain water and maintain its elasticity. Together, these ingredients are believed to promote joint function, reduce pain, and improve overall mobility, particularly in individuals who experience wear and tear on their joints due to age, physical activity, or injury.
The efficacy of glucosamine and chondroitin supplements can vary from person to person, and while some users report significant relief from joint discomfort, scientific studies on their effectiveness have produced mixed results. It's essential to consult with a healthcare provider before adding these supplements to your routine, especially if you have existing health conditions or are taking other medications. Many brands also blend these ingredients with additional vitamins, minerals, or herbal extracts to enhance their joint-supporting benefits, making it crucial to read labels and choose formulas that fit your specific needs.
Glucosamine and chondroitin formulas have long been popular supplements for managing arthritis symptoms, particularly osteoarthritis. Research has shown mixed results regarding their effectiveness. Some studies suggest that these compounds may help reduce pain and improve joint function in individuals with osteoarthritis, while others indicate that any benefits may be minimal or not significantly different from a placebo. Both glucosamine and chondroitin are natural substances found in joint cartilage, and they are thought to contribute to joint lubrication as well as its structural integrity.
If you’re considering glucosamine chondroitin supplements, it’s essential to consult with your healthcare provider first, especially if you are on other medications or have underlying health conditions. While these supplements are generally considered safe for many individuals, they may not be suitable for everyone. Additionally, the quality and concentration of glucosamine chondroitin products can vary greatly across brands, so it's advisable to choose reputable brands that undergo third-party testing for quality and potency. Keep in mind that managing arthritis often requires a multifaceted approach, including physical therapy, exercise, and possibly other medications or treatments recommended by a healthcare professional.
Based on user reviews, many individuals report experiencing noticeable improvements in their arthritis symptoms within a week of starting this supplement. For example, one user mentioned that their mother felt relief by the seventh day after beginning the regimen, with reduced inflammation and better comfort in her hand joints Read Review. Another reviewer indicated their father's symptoms vanished after just seven days, leading to a cessation of anti-inflammatories Read Review.
Conversely, some users noted longer time frames for improvements, with one user stating they felt significant benefits from the supplement after three months of continuous use Read Review. Overall, while a substantial number of users observed early results within a week, ongoing benefits and management of symptoms typically seem to solidify over a longer duration, such as three to six months Read Review, Read Review.
When it comes to managing arthritis, glucosamine and chondroitin supplements have garnered attention in scientific circles. A study conducted on 65 participants with knee osteoarthritis found that those who took a combination of these supplements alongside a supervised exercise regime reported significant improvements in pain and stiffness compared to those given a placebo. This highlights the potential benefits of glucosamine-chondroitin supplementation as a synergistic approach to enhance the effects of physical activity in alleviating knee arthritis symptoms [1].
These findings support the notion that integrating glucosamine and chondroitin with regular exercise may offer a more effective strategy for those suffering from knee arthritis. While more extensive research may be needed to fully understand the long-term effects and mechanisms at play, this study provides a compelling case for considering glucosamine-chondroitin supplements as part of an arthritis management plan.
Based on user reviews, a number of individuals have reported positive improvements in their arthritis symptoms after using this supplement. Many users noticed significant relief within the first week; one user shared that their mother experienced reduced pain and joint discomfort after just seven days Read Review. Additionally, another reviewer mentioned their father's symptoms completely vanished in the same time frame, making it easier for him to manage his condition without anti-inflammatories Read Review.
Some users highlighted the lasting benefits they observed after continued use, stating that their arthritis pain and inflammation improved significantly over months. For instance, one user reported that after three months of consistent use, they experienced substantial reductions in chronic pain in their hands and knees Read Review. Others echoed this sentiment, with testimonials describing enhanced mobility, decreased joint aching with weather changes, and overall better quality of life Read Review. It's worth noting that while many users have reported these benefits, individual results may vary.
Users have generally reported positive experiences when combining this supplement with other products to manage arthritis symptoms. For example, one user noted that their mother took this supplement alongside collagen, which resulted in a significant decrease in joint pain and twisting at night after just a week of use Read Review. Additionally, another reviewer mentioned using this supplement along with type 2 collagen over a six-month period, which greatly reduced their chronic pain in hands and knees, reinforcing the effectiveness of the combination Read Review.
Moreover, some users emphasized the benefits of taking this supplement in conjunction with other nutrients. One individual reported that their father experienced notable improvements in his arthritis and inflammation when combining the supplement with omega and vitamin D3 Read Review. This suggests that a multi-supplement approach can enhance the outcomes of managing arthritis, as many users noted enhanced mobility and reduced pain when they expanded their regimen to include complementary supplements.
Users report varying experiences regarding the appropriate dosage of Glucosamine Chondroitin formulas for treating arthritis. Many discovered that consistent use over a few weeks yields noticeable improvements in joint pain and mobility. For instance, one user noted a significant reduction in pain and improved joint function after her mother used the supplement for just one week Read Review. Another user found remarkable relief in their knee and back pain after a few weeks of taking Osteo Bi-Flex Read Review.
Some reviews indicate that adjusting the dosage based on activity levels or ongoing symptoms can lead to better outcomes. A user mentioned their rheumatologist recommended an increased dosage due to their active lifestyle, which further reinforced the supplement's benefits Read Review. Overall, while users emphasize the importance of consistency in taking Glucosamine Chondroitin, individual responses may vary, and it may be essential to consult with a healthcare professional to determine the right dose for one’s specific needs.
7.5
Pain relief effective
8 people found this helpful
I regularly purchase this medication for my mother, aged 69, who has suffered from arthritis for over 15 years. She is very pleased with its effects, which surpass those of sulfasalazine, with fewer side effects. She takes it for two months, then has a break for two months while continuing Boswellia. After her first dose, she felt relief by the seventh day. Now, her hand joints are less inflamed and more comfortable.
9
Effective pain relief
1 people found this helpful
I introduced this product to my 66-year-old father, who suffered greatly from knee pain due to arthritis. After just seven days, his symptoms vanished, and he no longer needed anti-inflammatories. He now takes this medication continuously and finds it very effective, especially compared to other options available in our local pharmacies.
9
Effective for arthritis
I have arthritis in my knee, and it works extremely well. I've been using it for three months and have no intention of stopping.
7.5
Constant pain reduction
2 people found this helpful
I have taken Osteo Bi-Flex alongside type 2 collagen for six months. As I suffer from arthritis, these products have greatly reduced my chronic pain in my hands and knees. While the condition remains, I feel I can support my joints effectively now.
6
Relief from pain
3 people found this helpful
I've used this product for three years, having first obtained a sample. As a fitness enthusiast, I experienced joint issues and was diagnosed with arthrosis. My rheumatologist advised an increased dosage due to my physical activities. This supplement has provided significant support for my arthritis and arthrosis in my knees and hips.
7.5
Reduced joint pain
6 people found this helpful
I purchased this for my mother, who began experiencing arthritis. After a week of use, she noticed less twisting of her joints at night and a significant decrease in pain. She also drinks collagen periodically. I recommend this complex for those with joint issues or as prevention.
9
Improved joint health
5 people found this helpful
I bought this nutritional supplement for my mother to support her arthritic joints. After searching for this specific triple-strength formula, I was pleased with the price. It arrived quickly and in perfect condition. Mom is very happy with the supplement, and we've observed that her joints no longer ache with changes in the weather, and her overall condition has improved. I will order this supplement again.
7
Noticeable improvement
I ordered this for my father with arthritis and joint inflammation. He noticed an improvement mid-course, especially taking it alongside omega and D3. I think it's wise for him to take it biannually.
9
Significant improvement
1 people found this helpful
Suffering from arthritis made it difficult to walk and caused severe back pain. After using Osteo Bi-Flex for a few weeks, I found I was walking much better, and my back pain subsided significantly. The improvement amazed me, enabling me to go on long walks again, with less reliance on my cane. It's also affordable for my fixed income.
8
Glucosamine and exercise enhance arthritis treatment
Nutrition supplementation combined with exercise versus exercise alone in treating knee osteoarthritis: a double-blinded, randomised, placebo-controlled trial.
We sought to determine whether a combination of a nutrition supplement, including glucosamine and chondroitin, along with supervised exercise, is more effective for knee osteoarthritis than exercise alone.
In a six-month double-blinded trial involving 65 participants, those who took the supplement experienced significant improvements in pain and stiffness earlier compared to those receiving a placebo.
This suggests that using glucosamine chondroitin supplementation along with exercise could be a more efficient treatment strategy for arthritis in the knee.
References
Liu W, Yu Y, Zhang Z, Li Z, Wu Y, et al. Nutrition supplementation combined with exercise versus exercise alone in treating knee osteoarthritis: a double-blinded, randomised, placebo-controlled trial. Age Ageing. 2025;54. doi:10.1093/ageing/afaf010