Last update
5/10/2025

Overview

SCIENTIFIC SCORE
Questionable
Based on 8 Researches
6.4
USERS' SCORE
Good
Based on 1 Review
8.5

Top Medical Research Studies

8
Vitamin A reduces pregnancy nausea
We conducted a double-masked, placebo-controlled trial involving 15,832 Nepali women to explore how vitamin A and beta-carotene supplementation affects pregnancy-related nausea and overall illness symptoms. Our observations showed that while there was no noticeable impact during the early stages of pregnancy, vitamin A supplementation made a significant difference in late pregnancy.

Specifically, we found that women who received vitamin A experienced a reduction in nausea. Additionally, symptoms such as faintness and night blindness were also less prevalent in those women. Beta-carotene supplementation did not yield the same benefits for nausea, highlighting the unique role of vitamin A in managing these symptoms.

Moreover, supplementation with vitamin A contributed to a shorter labor duration, which is promising for expectant mothers. It also helped reduce the postpartum risks of conditions like night blindness and loose stools. Overall, our findings indicate that ensuring adequate vitamin A intake can be important for improving reproductive health in women, particularly in areas with limited healthcare access.
Read More
8
Folic acid reduces nausea effectively
We explored the impact of folic acid combined with ferrous bisglycinate on nausea in pregnant women facing iron deficiency. In a controlled trial involving 120 participants, we discovered that the group taking ferrous bisglycinate with folinic acid reported significantly fewer instances of nausea and other discomforts compared to those receiving a standard iron supplement.

Both groups saw improvements in iron status and related blood markers over six months, but our findings clearly indicated that the test group had a more tolerable experience. Folic acid may play a vital role in making iron supplementation easier for pregnant women.
Read More
7
Zinc treatment reduces nausea risk
We conducted a study to evaluate how effective NPC-25, a new form of zinc, is compared to a well-known treatment, NOBELZIN™, for patients with low zinc levels. Participants in this trial had their zinc levels checked and were grouped to receive either NPC-25 or NOBELZIN™.

For a period of up to 24 weeks, we aimed to maintain their zinc levels within a specific target range while closely monitoring for side effects. One of our main goals was to see if NPC-25 could maintain these target zinc levels similarly to NOBELZIN™.

Our findings revealed that NPC-25 was indeed non-inferior to NOBELZIN™, meaning it worked just as well. Importantly, we also observed that those taking NPC-25 reported fewer digestive issues, like nausea and vomiting. This suggests that while both treatments were effective, NPC-25 might be the gentler option.
Read More

Most Useful Reviews

9
No nausea
121 people found this helpful
I'm thrilled to have discovered these One a Day Women's Petites vitamins! Throughout adulthood, vitamins often made me nauseous, making them seem unworthwhile. My doctor advised me to take children's vitamins, which worked temporarily, but I needed something better. These petite vitamins are much easier to swallow, and I take two daily without any nausea or side effects. In fact, I've noticed a significant improvement in my health when I consistently take these. I recommend them to anyone who struggles with pills or experiences nausea when taking vitamins.
Read More

Medical Researches

SCIENTIFIC SCORE
Questionable
Based on 8 Researches
6.4
  • All Researches
8
Vitamin A reduces pregnancy nausea
We conducted a double-masked, placebo-controlled trial involving 15,832 Nepali women to explore how vitamin A and beta-carotene supplementation affects pregnancy-related nausea and overall illness symptoms. Our observations showed that while there was no noticeable impact during the early stages of pregnancy, vitamin A supplementation made a significant difference in late pregnancy.

Specifically, we found that women who received vitamin A experienced a reduction in nausea. Additionally, symptoms such as faintness and night blindness were also less prevalent in those women. Beta-carotene supplementation did not yield the same benefits for nausea, highlighting the unique role of vitamin A in managing these symptoms.

Moreover, supplementation with vitamin A contributed to a shorter labor duration, which is promising for expectant mothers. It also helped reduce the postpartum risks of conditions like night blindness and loose stools. Overall, our findings indicate that ensuring adequate vitamin A intake can be important for improving reproductive health in women, particularly in areas with limited healthcare access.
Read More
8
Telephonic intervention boosts adherence
We set out to explore how a telephonic intervention could improve adherence to iron and folic acid supplements among pregnant women suffering from anemia. This study involved 286 participants who received phone reminders and messages for one month.

The results showed that the intervention significantly boosted adherence, tripling participation in the experimental group compared to a slight increase in the control group. Moreover, the telephonic support also helped reduce side effects and improved hemoglobin levels. Overall, the findings suggest that incorporating phone calls can support better health outcomes for pregnant women.
Read More
8
Folic acid reduces nausea effectively
We explored the impact of folic acid combined with ferrous bisglycinate on nausea in pregnant women facing iron deficiency. In a controlled trial involving 120 participants, we discovered that the group taking ferrous bisglycinate with folinic acid reported significantly fewer instances of nausea and other discomforts compared to those receiving a standard iron supplement.

Both groups saw improvements in iron status and related blood markers over six months, but our findings clearly indicated that the test group had a more tolerable experience. Folic acid may play a vital role in making iron supplementation easier for pregnant women.
Read More
7
Zinc treatment reduces nausea risk
We conducted a study to evaluate how effective NPC-25, a new form of zinc, is compared to a well-known treatment, NOBELZIN™, for patients with low zinc levels. Participants in this trial had their zinc levels checked and were grouped to receive either NPC-25 or NOBELZIN™.

For a period of up to 24 weeks, we aimed to maintain their zinc levels within a specific target range while closely monitoring for side effects. One of our main goals was to see if NPC-25 could maintain these target zinc levels similarly to NOBELZIN™.

Our findings revealed that NPC-25 was indeed non-inferior to NOBELZIN™, meaning it worked just as well. Importantly, we also observed that those taking NPC-25 reported fewer digestive issues, like nausea and vomiting. This suggests that while both treatments were effective, NPC-25 might be the gentler option.
Read More
7
Zinc treatment in hypozincemia study
We explored the impact of zinc acetate dihydrate on several symptoms, including nausea, through a comprehensive study that assessed its safety and effectiveness for treating hypozincemia over a 52-week period. From the data collected, we observed an overall adverse reaction rate of 9.4%, with nausea reported in 1.4% of patients.

Despite nausea being a concern, the benefit of zinc acetate dihydrate for other indications was notable, with an efficacy rate of 83%. For patients experiencing symptoms such as pressure ulcers or stomatitis, the effectiveness was strikingly high. However, the specific effect of zinc on nausea is not definitively isolated within the study results, making it hard to gauge its direct and unique benefits.

In essence, while zinc acetate dihydrate shows promise for a variety of symptoms, including nausea, the evidence does not conclusively highlight its effectiveness for this particular issue on its own. Overall, it appears that zinc treatment can contribute positively to addressing several related health problems.
Read More

User Reviews

USERS' SCORE
Good
Based on 1 Review
8.5
  • All Reviews
  • Positive Reviews
  • Negative Reviews
9
No nausea
121 people found this helpful
I'm thrilled to have discovered these One a Day Women's Petites vitamins! Throughout adulthood, vitamins often made me nauseous, making them seem unworthwhile. My doctor advised me to take children's vitamins, which worked temporarily, but I needed something better. These petite vitamins are much easier to swallow, and I take two daily without any nausea or side effects. In fact, I've noticed a significant improvement in my health when I consistently take these. I recommend them to anyone who struggles with pills or experiences nausea when taking vitamins.
Read More

Frequently Asked Questions

No FAQs are available for this product and symptom.

References

  1. Christian P, West KP, Khatry SK, Katz J, LeClerq SC, et al. Vitamin A or beta-carotene supplementation reduces symptoms of illness in pregnant and lactating Nepali women. J Nutr. 2000;130:2675.
  2. Asaoka D, Ishihara T, Ezoe S, Hamada I, Kitamura M, et al. Randomized, multicenter, active-controlled open-label study of NPC-25, zinc histidine hydrate, (non-inferiority to NOBELZIN™, zinc acetate dihydrate) for patients with hypozincemia. J Trace Elem Med Biol. 2025;87:127558. 10.1016/j.jtemb.2024.127558
  3. Ezoe S, Ishihara T, Hosogai T, Kokubo T. Post-marketing surveillance of zinc acetate dihydrate for hypozincemia in Japan. Pharmazie. 2024;79:29. 10.1691/ph.2024.3630
  4. Parvizi A, Haddadi S, Akbari M, Akbarpour M, Taghipour Rudsari F, et al. Comparing the Effect of Zinc-impregnated Pharyngeal Packs with Conventional Methods on the Level of Sore Throat Among Patients Undergoing Septorhinoplasty. Anesth Pain Med. 2022;12:e127262. 10.5812/aapm-127262
  5. Nuzhat S, Ahmed T, Alam J, Billal SM, Khan AI, et al. New formulation zinc sulphate acceptability and adherence in children with acute diarrhoea: A prospective, open-label, interventional study in Bangladesh. J Paediatr Child Health. 2022;58:1215. 10.1111/jpc.15953
  6. Sharma S, Smitha MV, Balakrishnan D. Telephonic intervention to combat non-adherence to oral iron-folic acid supplementation in pregnancy: A randomized controlled trial. Eur J Obstet Gynecol Reprod Biol X. 2023;20:100235. 10.1016/j.eurox.2023.100235
  7. Adu-Afarwuah S, Arnold CD, Lartey A, Okronipa H, Maleta K, et al. Prevalence of morbidity symptoms among pregnant and postpartum women receiving different nutrient supplements in Ghana and Malawi: A secondary outcome analysis of two randomised controlled trials. Matern Child Nutr. 2023;19:e13501. 10.1111/mcn.13501
  8. Bumrungpert A, Pavadhgul P, Piromsawasdi T, Mozafari MR. Efficacy and Safety of Ferrous Bisglycinate and Folinic Acid in the Control of Iron Deficiency in Pregnant Women: A Randomized, Controlled Trial. Nutrients. 2022;14. 10.3390/nu14030452
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