Infographics 
Overview
SCIENTIFIC SCORE
Likely Very Effective
Based on 1 Research
9
USERS' SCORE
Good
Based on 2 Reviews
8.3
Top Medical Research Studies
9
We investigated the potential of 2D layered calcium disilicide nanoparticles (CSNs) to treat rheumatoid arthritis (RA) through their unique properties. CSNs are crafted using a straightforward method of aqueous exfoliation, and their hydrolysis generates several beneficial components including hydrogen gas, alkaline calcium hydroxide (Ca(OH)), and silica.
These components support healing by improving anti-oxidation and reducing inflammation while promoting bone regeneration. The hydrogen gas helps eliminate harmful radicals and can alter macrophage behavior, which is crucial for regulating inflammation. Meanwhile, calcium hydroxide works to balance the acidic environment in the joints, limiting the harmful activity of osteoclasts, the cells that break down bone.
Furthermore, the calcium released can bind with phosphates, aiding in the formation of calcium phosphate, which is essential for bone mineralization. We confirmed these multifaceted benefits through tests on arthritic mice and rabbits, demonstrating that CSNs can provide a promising, biocompatible treatment strategy that enhances therapy beyond just addressing inflammation.
This study emphasizes the importance of calcium and its interactive role in more comprehensive arthritis treatments, fostering both anti-inflammatory and pro-osteogenic effects vital for joint health.
These components support healing by improving anti-oxidation and reducing inflammation while promoting bone regeneration. The hydrogen gas helps eliminate harmful radicals and can alter macrophage behavior, which is crucial for regulating inflammation. Meanwhile, calcium hydroxide works to balance the acidic environment in the joints, limiting the harmful activity of osteoclasts, the cells that break down bone.
Furthermore, the calcium released can bind with phosphates, aiding in the formation of calcium phosphate, which is essential for bone mineralization. We confirmed these multifaceted benefits through tests on arthritic mice and rabbits, demonstrating that CSNs can provide a promising, biocompatible treatment strategy that enhances therapy beyond just addressing inflammation.
This study emphasizes the importance of calcium and its interactive role in more comprehensive arthritis treatments, fostering both anti-inflammatory and pro-osteogenic effects vital for joint health.
Read More
Most Useful Reviews
7.5
Joint improvement
43 people found this helpful
This is an excellent product! I've tried other clays, but Tierra Buena dissolves more easily and is lighter. I use it daily and have noticed my aching knees—previously attributed to arthritis—have lessened significantly. I’ve adjusted my diet and exercise, and believe this clay is flushing out impurities, promoting my overall health.
Read More
7.5
Joint comfort
26 people found this helpful
The best clay! I cherish this clay! At 29 with severe rheumatoid arthritis, it aids in reducing fluid on my joints and alleviates pain. Unbelievably, it also helped my mother with her severe stomach issues and my brother's flu symptoms.
Read More
Medical Researches
SCIENTIFIC SCORE
Likely Very Effective
Based on 1 Research
9
- All Researches
9
We investigated the potential of 2D layered calcium disilicide nanoparticles (CSNs) to treat rheumatoid arthritis (RA) through their unique properties. CSNs are crafted using a straightforward method of aqueous exfoliation, and their hydrolysis generates several beneficial components including hydrogen gas, alkaline calcium hydroxide (Ca(OH)), and silica.
These components support healing by improving anti-oxidation and reducing inflammation while promoting bone regeneration. The hydrogen gas helps eliminate harmful radicals and can alter macrophage behavior, which is crucial for regulating inflammation. Meanwhile, calcium hydroxide works to balance the acidic environment in the joints, limiting the harmful activity of osteoclasts, the cells that break down bone.
Furthermore, the calcium released can bind with phosphates, aiding in the formation of calcium phosphate, which is essential for bone mineralization. We confirmed these multifaceted benefits through tests on arthritic mice and rabbits, demonstrating that CSNs can provide a promising, biocompatible treatment strategy that enhances therapy beyond just addressing inflammation.
This study emphasizes the importance of calcium and its interactive role in more comprehensive arthritis treatments, fostering both anti-inflammatory and pro-osteogenic effects vital for joint health.
These components support healing by improving anti-oxidation and reducing inflammation while promoting bone regeneration. The hydrogen gas helps eliminate harmful radicals and can alter macrophage behavior, which is crucial for regulating inflammation. Meanwhile, calcium hydroxide works to balance the acidic environment in the joints, limiting the harmful activity of osteoclasts, the cells that break down bone.
Furthermore, the calcium released can bind with phosphates, aiding in the formation of calcium phosphate, which is essential for bone mineralization. We confirmed these multifaceted benefits through tests on arthritic mice and rabbits, demonstrating that CSNs can provide a promising, biocompatible treatment strategy that enhances therapy beyond just addressing inflammation.
This study emphasizes the importance of calcium and its interactive role in more comprehensive arthritis treatments, fostering both anti-inflammatory and pro-osteogenic effects vital for joint health.
Read More
User Reviews
USERS' SCORE
Good
Based on 2 Reviews
8.3
- All Reviews
- Positive Reviews
- Negative Reviews
7.5
Joint improvement
43 people found this helpful
This is an excellent product! I've tried other clays, but Tierra Buena dissolves more easily and is lighter. I use it daily and have noticed my aching knees—previously attributed to arthritis—have lessened significantly. I’ve adjusted my diet and exercise, and believe this clay is flushing out impurities, promoting my overall health.
Read More
7.5
Joint comfort
26 people found this helpful
The best clay! I cherish this clay! At 29 with severe rheumatoid arthritis, it aids in reducing fluid on my joints and alleviates pain. Unbelievably, it also helped my mother with her severe stomach issues and my brother's flu symptoms.
Read More
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References
- Ji P, Qiu S, Huang J, Wang L, Wang Y, et al. Hydrolysis of 2D Nanosheets Reverses Rheumatoid Arthritis Through Anti-Inflammation and Osteogenesis. Adv Mater. 2025;37:e2415543. 10.1002/adma.202415543
