Last update
5/23/2025

Overview

SCIENTIFIC SCORE
Questionable
Based on 3 Researches
6
USERS' SCORE
Good
Based on 2 Reviews
8.5

Top Medical Research Studies

We reviewed various studies to see how effective glucosamine and similar chondroprotectors are for treating chronic back pain.

Our findings indicated that these drugs may provide pain relief comparable to traditional anti-inflammatory medications, showing potential benefits in reducing inflammation and improving function.

However, the overall evidence suggests that while they can help with osteoarthritis, the support for back pain relief specifically remains limited. This means glucosamine might not be the go-to treatment for everyone suffering from back issues.
Read More
We examined the effectiveness of a chondroprotector called Sustagard Artro against traditional nonsteroidal anti-inflammatory drugs (NSAIDs) for easing lower back pain.

Our study involved sixty patients with spondylarthrosis, divided into two groups receiving either Sustagard Artro or NSAIDs.

After treatment, both groups showed a similar level of pain relief, with no significant differences in effectiveness. This suggests that Sustagard Artro may be a viable alternative to NSAIDs for back pain management.
Read More
5
Glucosamine injections not effective
We examined the effectiveness of glucosamine injections for treating chronic lower back pain in a pilot study. Thirty participants, all struggling with severe back pain for an average of 8.5 years, received injections into their lumbar discs.

After one year, we compared their pain and disability scores to see if there were improvements. Unfortunately, the results indicated no significant change in their condition. While this study highlights the need for more rigorous trials, we're left with no strong evidence to support glucosamine injections for back pain relief.
Read More

Most Useful Reviews

9
Immediate relief
3 people found this helpful
THEY ARE INCREDIBLE. My doctor recommended I start taking glucosamine for my knee. I began with these and the relief was almost immediate. After my insurance approved an over-the-counter alternative, the pain returned to my knee within a week. I reverted back to Puritan's Pride tablets, and once again, relief came swiftly. I can only conclude that it’s the MSM Joint Soother that makes the difference. Whatever the reason, I won’t use anything else but Puritan's Pride; it genuinely works.
Read More
7.5
Needs consistency
2 people found this helpful
Works, but I need to stay on it. In my late 20s, I have always had pain in one knee. When the other began cracking and aching, I decided to try this product. It has helped, but I must remember to keep taking the doses. Being off it for a week, I noticed that the pain and cracking returned; on average, I take 1-2 capsules daily, so I recommend it.
Read More

Medical Researches

SCIENTIFIC SCORE
Questionable
Based on 3 Researches
6
  • All Researches
We reviewed various studies to see how effective glucosamine and similar chondroprotectors are for treating chronic back pain.

Our findings indicated that these drugs may provide pain relief comparable to traditional anti-inflammatory medications, showing potential benefits in reducing inflammation and improving function.

However, the overall evidence suggests that while they can help with osteoarthritis, the support for back pain relief specifically remains limited. This means glucosamine might not be the go-to treatment for everyone suffering from back issues.
Read More
We examined the effectiveness of a chondroprotector called Sustagard Artro against traditional nonsteroidal anti-inflammatory drugs (NSAIDs) for easing lower back pain.

Our study involved sixty patients with spondylarthrosis, divided into two groups receiving either Sustagard Artro or NSAIDs.

After treatment, both groups showed a similar level of pain relief, with no significant differences in effectiveness. This suggests that Sustagard Artro may be a viable alternative to NSAIDs for back pain management.
Read More
5
Glucosamine injections not effective
We examined the effectiveness of glucosamine injections for treating chronic lower back pain in a pilot study. Thirty participants, all struggling with severe back pain for an average of 8.5 years, received injections into their lumbar discs.

After one year, we compared their pain and disability scores to see if there were improvements. Unfortunately, the results indicated no significant change in their condition. While this study highlights the need for more rigorous trials, we're left with no strong evidence to support glucosamine injections for back pain relief.
Read More

User Reviews

USERS' SCORE
Good
Based on 2 Reviews
8.5
  • All Reviews
  • Positive Reviews
  • Negative Reviews
9
Immediate relief
3 people found this helpful
THEY ARE INCREDIBLE. My doctor recommended I start taking glucosamine for my knee. I began with these and the relief was almost immediate. After my insurance approved an over-the-counter alternative, the pain returned to my knee within a week. I reverted back to Puritan's Pride tablets, and once again, relief came swiftly. I can only conclude that it’s the MSM Joint Soother that makes the difference. Whatever the reason, I won’t use anything else but Puritan's Pride; it genuinely works.
Read More
7.5
Needs consistency
2 people found this helpful
Works, but I need to stay on it. In my late 20s, I have always had pain in one knee. When the other began cracking and aching, I decided to try this product. It has helped, but I must remember to keep taking the doses. Being off it for a week, I noticed that the pain and cracking returned; on average, I take 1-2 capsules daily, so I recommend it.
Read More

Frequently Asked Questions

No FAQs are available for this product and symptom.

References

  1. Shavlovskaya OA, Romanov ID, Artemenko AR, Kuznetsov SL. [Experience of using the chondroprotector Sustagard Artro (sashe) in the treatment of lower back pain]. Zh Nevrol Psikhiatr Im S S Korsakova. 2019;119:40. 10.17116/jnevro201911910140
  2. Danilov AB, Grigorenko NV. [An antinociceptive effect of chondroprotectors: a myth or a reality?]. Zh Nevrol Psikhiatr Im S S Korsakova. 2015;115:84. 10.17116/jnevro20151159184-89
  3. Klein RG, Eek BC, O'Neill CW, Elin C, Mooney V, et al. Biochemical injection treatment for discogenic low back pain: a pilot study. Spine J. 2003;3:220.
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