Overview
SCIENTIFIC SCORE
Moderately Effective
Based on 4 Researches
8
USERS' SCORE
Good
Based on 2 Reviews
8.6
Supplement Facts
Serving Size: 3 Tablets
Amount Per Serving
%DV
Vitamin C (as Ascorbic Acid)
100 mg
111%
Calcium (from Calcium Phosphate, Calcium Stearate)
30 mg
2%
L-Lysine (from L-Lysine Hydrochloride)
1.5 g
†
Garlic Bulb (deodorized)
200 mg
†
Echinacea purpurea Aerial Parts Extract 4:1
100 mg
†
Propolis
25 mg
†
Licorice Root Extract 4:1
15 mg
†
Top Medical Research Studies
9
L-lysine may slow atherosclerosis
We explored how L-lysine, specifically the iNOS inhibitor N-iminoethyl-L-lysine (L-NIL), affects the progression of atherosclerosis in rabbits with high cholesterol. In our controlled study, we compared rabbits treated with L-NIL, a vehicle, or L-arginine after being fed a cholesterol-rich diet.
The results were promising; L-NIL limited the progression of atherosclerosis in the rabbits. We observed notable differences in arterial health, with less disease advancement in the L-NIL group compared to the control groups. L-arginine showed some benefits, but not to the same extent as L-NIL.
The results were promising; L-NIL limited the progression of atherosclerosis in the rabbits. We observed notable differences in arterial health, with less disease advancement in the L-NIL group compared to the control groups. L-arginine showed some benefits, but not to the same extent as L-NIL.
8
We investigated a newly developed human antibody called FAP2M21 that targets PCSK9, a protein that affects cholesterol levels. This antibody has shown excellent binding properties and can effectively inhibit the reduction of LDL cholesterol uptake in liver cells.
In experiments with mice, administering FAP2M21 significantly reduced serum LDL cholesterol levels, depending on the dosage.
While the results indicate the antibody could be a strong candidate for treating high cholesterol, further studies will be necessary to fully understand its potential in humans.
In experiments with mice, administering FAP2M21 significantly reduced serum LDL cholesterol levels, depending on the dosage.
While the results indicate the antibody could be a strong candidate for treating high cholesterol, further studies will be necessary to fully understand its potential in humans.
8
We examined the impact of L-lysine, delivered via a special method, on reducing high cholesterol. The study involved using a specific type of siRNA to target apolipoprotein B in mice.
Our findings showed a successful reduction in harmful LDL cholesterol levels in genetically modified mice, without any signs of liver damage. However, significant effects in wider populations remain unclear.
Our findings showed a successful reduction in harmful LDL cholesterol levels in genetically modified mice, without any signs of liver damage. However, significant effects in wider populations remain unclear.
Most Useful Reviews
9.5
Boosts immune function
This is a high-quality supplement with effective ingredients. Lysine helps with herpes and boosts my immunity. The garlic odour is negligible, and the capsules are easy to swallow. Overall, it's a reliable remedy for colds and provides support for high cholesterol as well.
8.8
Supports cholesterol reduction
Lysine is an essential amino acid crucial for health. It aids in collagen synthesis, strengthening bones and muscles, and promoting calcium absorption, which helps prevent osteoporosis. It plays a vital role in the immune system and may reduce herpes virus incidence. Although the mechanism is not fully understood, it’s believed to inhibit arginine, which can accelerate herpes cell division. Sufficient lysine levels are also important for managing high cholesterol.
Medical Researches
SCIENTIFIC SCORE
Moderately Effective
Based on 4 Researches
8
- All Researches
9
L-lysine may slow atherosclerosis
We explored how L-lysine, specifically the iNOS inhibitor N-iminoethyl-L-lysine (L-NIL), affects the progression of atherosclerosis in rabbits with high cholesterol. In our controlled study, we compared rabbits treated with L-NIL, a vehicle, or L-arginine after being fed a cholesterol-rich diet.
The results were promising; L-NIL limited the progression of atherosclerosis in the rabbits. We observed notable differences in arterial health, with less disease advancement in the L-NIL group compared to the control groups. L-arginine showed some benefits, but not to the same extent as L-NIL.
The results were promising; L-NIL limited the progression of atherosclerosis in the rabbits. We observed notable differences in arterial health, with less disease advancement in the L-NIL group compared to the control groups. L-arginine showed some benefits, but not to the same extent as L-NIL.
8
We investigated a newly developed human antibody called FAP2M21 that targets PCSK9, a protein that affects cholesterol levels. This antibody has shown excellent binding properties and can effectively inhibit the reduction of LDL cholesterol uptake in liver cells.
In experiments with mice, administering FAP2M21 significantly reduced serum LDL cholesterol levels, depending on the dosage.
While the results indicate the antibody could be a strong candidate for treating high cholesterol, further studies will be necessary to fully understand its potential in humans.
In experiments with mice, administering FAP2M21 significantly reduced serum LDL cholesterol levels, depending on the dosage.
While the results indicate the antibody could be a strong candidate for treating high cholesterol, further studies will be necessary to fully understand its potential in humans.
8
We examined the impact of L-lysine, delivered via a special method, on reducing high cholesterol. The study involved using a specific type of siRNA to target apolipoprotein B in mice.
Our findings showed a successful reduction in harmful LDL cholesterol levels in genetically modified mice, without any signs of liver damage. However, significant effects in wider populations remain unclear.
Our findings showed a successful reduction in harmful LDL cholesterol levels in genetically modified mice, without any signs of liver damage. However, significant effects in wider populations remain unclear.
7
We investigated how high-protein diets and leucine supplementation impact mice, focusing on energy balance and body composition over 14 weeks.
Interestingly, we found that neither high-protein diets nor leucine supplementation influenced body weight, energy expenditure, or protein expression in the muscle.
However, plasma cholesterol levels significantly dropped in the high-protein and leucine-supplemented groups compared to those on a standard diet. Yet, there were concerns, such as increased triglycerides in the high-protein group.
Overall, while cholesterol levels showed some promise, the effects were not as widespread as we had hoped.
Interestingly, we found that neither high-protein diets nor leucine supplementation influenced body weight, energy expenditure, or protein expression in the muscle.
However, plasma cholesterol levels significantly dropped in the high-protein and leucine-supplemented groups compared to those on a standard diet. Yet, there were concerns, such as increased triglycerides in the high-protein group.
Overall, while cholesterol levels showed some promise, the effects were not as widespread as we had hoped.
User Reviews
USERS' SCORE
Good
Based on 2 Reviews
8.6
- All Reviews
- Positive Reviews
- Negative Reviews
9.5
Boosts immune function
This is a high-quality supplement with effective ingredients. Lysine helps with herpes and boosts my immunity. The garlic odour is negligible, and the capsules are easy to swallow. Overall, it's a reliable remedy for colds and provides support for high cholesterol as well.
8.8
Supports cholesterol reduction
Lysine is an essential amino acid crucial for health. It aids in collagen synthesis, strengthening bones and muscles, and promoting calcium absorption, which helps prevent osteoporosis. It plays a vital role in the immune system and may reduce herpes virus incidence. Although the mechanism is not fully understood, it’s believed to inhibit arginine, which can accelerate herpes cell division. Sufficient lysine levels are also important for managing high cholesterol.
Frequently Asked Questions
No FAQs are available for this product and symptom.
References
- Xu M, Lei G, Chen M, Wang K, Lv W, et al. Development of a novel, fully human, anti-PCSK9 antibody with potent hypolipidemic activity by utilizing phage display-based strategy. EBioMedicine. 2021;65:103250. doi:10.1016/j.ebiom.2021.103250
- Noatsch A, Petzke KJ, Millrose MK, Klaus S. Body weight and energy homeostasis was not affected in C57BL/6 mice fed high whey protein or leucine-supplemented low-fat diets. Eur J Nutr. 2011;50:479. doi:10.1007/s00394-010-0155-2
- Watanabe K, Harada-Shiba M, Suzuki A, Gokuden R, Kurihara R, et al. In vivo siRNA delivery with dendritic poly(L-lysine) for the treatment of hypercholesterolemia. Mol Biosyst. 2009;5:1306. doi:10.1039/b900880b
- Behr-Roussel D, Rupin A, Simonet S, Bonhomme E, Coumailleau S, et al. Effect of chronic treatment with the inducible nitric oxide synthase inhibitor N-iminoethyl-L-lysine or with L-arginine on progression of coronary and aortic atherosclerosis in hypercholesterolemic rabbits. Circulation. 2000;102:1033.
