This study explored how quercetin may help reduce inflammation associated with sinusitis using a rat model. We observed that introducing lipopolysaccharides (LPS) caused significant inflammation in nasal and sinus areas, as well as in the lungs and brain.
When we administered quercetin after the LPS treatment, it notably decreased inflammatory markers like TNF-α and IL-6. The results indicated reduced inflammation in nasal and lung tissues, showcasing quercetin's potential benefits. However, while there were encouraging findings, its effects on brain inflammation were more limited.
Read More
8
Quercetin enhances mucus transport
Quercetin increases cystic fibrosis transmembrane conductance regulator-mediated chloride transport and ciliary beat frequency: therapeutic implications for chronic rhinosinusitis.
We explored how quercetin might help sinusitis by boosting chloride secretion and improving ciliary beat frequency in cultured sinonasal cells. In our analysis, this compound showed notable ability to enhance these functions, suggesting it could promote better mucus clearance from the sinuses.
The study involved primary cultures of human and murine sinonasal epithelial cells and demonstrated quercetin's effectiveness in increasing chloride transport. This implies potential therapeutic benefits for individuals suffering from chronic rhinosinusitis.
Read More
7
Quercetin reduces inflammation in sinusitis
Quercetin inhibits expression of inflammatory cytokines through attenuation of NF-kappaB and p38 MAPK in HMC-1 human mast cell line.
We explored how quercetin affects sinusitis by examining its impact on human mast cells. Specifically, we focused on the expression of inflammatory cytokines after stimulating the cells.
Quercetin showed promise by reducing the gene expression and production of key inflammatory signals like TNF-alpha and IL-6. It did this by dampening the activation of NF-kappaB and p38 MAPK pathways, both crucial for inflammation.
This suggests that quercetin may be beneficial for managing conditions like sinusitis linked to mast cell activity.
Read More
Most Useful Reviews
9
Skin and allergy relief
119 people found this helpful
Quercetin and bromelain are potent natural ingredients that help alleviate allergic and inflammatory disorders, including sinusitis. They relieve asthma symptoms, promote phlegm elimination, and reduce inflammation in cartilage and joints. As someone with arthritis and allergies, Quercetin has been a lifesaver for me, and I take it regularly. I highly recommend it!
Read More
7.5
Improved nasal congestion
33 people found this helpful
I started taking one tablet twice daily for my chronic sinusitis. After a month, my headaches from rhinitis faded, and I no longer wake up with a clogged nose. When my rhinitis was severe, I took two tablets twice a day, and I felt progressively better. I intend to continue this.
Read More
9
Good for seasonal allergies
30 people found this helpful
I struggled with a stuffy nose due to seasonal allergies, but after trying this product, I was amazed at how effective the first tablet was. That night I could breathe easily and sleep well. Quercetin is a valuable alternative for those looking to avoid medications. Highly recommend it for sinusitis!
This study explored how quercetin may help reduce inflammation associated with sinusitis using a rat model. We observed that introducing lipopolysaccharides (LPS) caused significant inflammation in nasal and sinus areas, as well as in the lungs and brain.
When we administered quercetin after the LPS treatment, it notably decreased inflammatory markers like TNF-α and IL-6. The results indicated reduced inflammation in nasal and lung tissues, showcasing quercetin's potential benefits. However, while there were encouraging findings, its effects on brain inflammation were more limited.
Read More
8
Quercetin enhances mucus transport
Quercetin increases cystic fibrosis transmembrane conductance regulator-mediated chloride transport and ciliary beat frequency: therapeutic implications for chronic rhinosinusitis.
We explored how quercetin might help sinusitis by boosting chloride secretion and improving ciliary beat frequency in cultured sinonasal cells. In our analysis, this compound showed notable ability to enhance these functions, suggesting it could promote better mucus clearance from the sinuses.
The study involved primary cultures of human and murine sinonasal epithelial cells and demonstrated quercetin's effectiveness in increasing chloride transport. This implies potential therapeutic benefits for individuals suffering from chronic rhinosinusitis.
Read More
7
Quercetin reduces inflammation in sinusitis
Quercetin inhibits expression of inflammatory cytokines through attenuation of NF-kappaB and p38 MAPK in HMC-1 human mast cell line.
We explored how quercetin affects sinusitis by examining its impact on human mast cells. Specifically, we focused on the expression of inflammatory cytokines after stimulating the cells.
Quercetin showed promise by reducing the gene expression and production of key inflammatory signals like TNF-alpha and IL-6. It did this by dampening the activation of NF-kappaB and p38 MAPK pathways, both crucial for inflammation.
This suggests that quercetin may be beneficial for managing conditions like sinusitis linked to mast cell activity.
Read More
User Reviews
USERS' SCORE
Moderately Good
Based on 41 Reviews
7.4
All Reviews
Positive Reviews
Negative Reviews
9
Skin and allergy relief
119 people found this helpful
Quercetin and bromelain are potent natural ingredients that help alleviate allergic and inflammatory disorders, including sinusitis. They relieve asthma symptoms, promote phlegm elimination, and reduce inflammation in cartilage and joints. As someone with arthritis and allergies, Quercetin has been a lifesaver for me, and I take it regularly. I highly recommend it!
Read More
7.5
Improved nasal congestion
33 people found this helpful
I started taking one tablet twice daily for my chronic sinusitis. After a month, my headaches from rhinitis faded, and I no longer wake up with a clogged nose. When my rhinitis was severe, I took two tablets twice a day, and I felt progressively better. I intend to continue this.
Read More
9
Good for seasonal allergies
30 people found this helpful
I struggled with a stuffy nose due to seasonal allergies, but after trying this product, I was amazed at how effective the first tablet was. That night I could breathe easily and sleep well. Quercetin is a valuable alternative for those looking to avoid medications. Highly recommend it for sinusitis!
Read More
9
Breathing improvement
7 people found this helpful
This product is essential for treating my sinusitis. I experienced difficulty breathing, snoring, and sleep apnea, but thankfully, my symptoms have nearly resolved. I continue to use it regularly.
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8
Nasal congestion relief
6 people found this helpful
I bought this due to my chronic sinusitis and was intrigued by the reviews. Since starting, my nasal congestion has improved, and my stress levels have decreased. I hope it also assists with my allergic rhinitis during pollen season.
Sinusitis, commonly referred to as a sinus infection, is the inflammation of the sinus cavities, which can cause various uncomfortable symptoms. This condition occurs when the nasal passages and sinuses become swollen or inflamed, often due to infections, allergies, or irritants. The sinuses, which are air-filled spaces located within the bones surrounding the nose, can become congested and trapped with mucus, leading to pain, pressure, and difficulty breathing. Symptoms may include a runny or stuffy nose, headache, facial tenderness, fever, and a reduced sense of smell and taste.
There are two main types of sinusitis: acute and chronic. Acute sinusitis typically lasts for a short period, often following a cold or respiratory infection, while chronic sinusitis can persist for several months or longer, often requiring medical intervention. Treatment options may include over-the-counter medications for symptom relief, nasal sprays, or, in some cases, antibiotics if a bacterial infection is suspected. If sinusitis becomes a recurring issue, it is advisable to consult a healthcare professional for a thorough evaluation and tailored treatment plan.
Quercetin is a naturally occurring flavonoid that is found in a variety of fruits, vegetables, and grains. Known for its antioxidant properties, quercetin is believed to help combat oxidative stress in the body, which can contribute to various health issues. You can commonly find it in foods such as apples, onions, berries, and citrus fruits, as well as in leafy greens. This makes it a popular dietary supplement among health enthusiasts looking to enhance their overall wellness.
Beyond its antioxidant capacity, quercetin is also being researched for its potential anti-inflammatory effects and benefits for immune support. Some studies suggest that it may help reduce allergy symptoms and improve exercise performance by decreasing muscle fatigue. With its wide range of potential health benefits, quercetin is often marketed as a natural remedy for various ailments, although it’s essential to consult a healthcare professional before starting any new supplement regimen to ensure its safety and effectiveness for your specific needs.
Quercetin is a flavonoid found in many fruits, vegetables, and grains, and it's renowned for its antioxidant and anti-inflammatory properties. Some studies suggest that quercetin may help alleviate symptoms associated with sinusitis. Its ability to stabilize mast cells can potentially reduce the release of histamines, which are responsible for allergy symptoms, including nasal congestion and inflammation. For individuals suffering from sinusitis with an allergic component, incorporating quercetin through supplements or dietary sources might provide some relief.
However, while quercetin shows promise as a natural remedy to support respiratory health, it is important to approach it with cautious optimism. Most evidence surrounding quercetin's effectiveness in treating sinusitis is anecdotal or derived from preliminary research. As always, it's best to consult a healthcare provider before starting any new supplement regimen, especially for chronic conditions like sinusitis. They can help determine the best treatment plan tailored to your individual needs, potentially in combination with other therapies.
Based on user reviews, the timeframe to see results from using this supplement for sinusitis varies among individuals, but many users report noticing significant improvements within one to four weeks. For instance, one user indicated that after taking a tablet twice daily for a month, their headaches from rhinitis faded, and they no longer woke up with a clogged nose Read Review. Another user remarked that within weeks of starting the supplement, they experienced considerable relief from sinus congestion and inflammation Read Review.
Some users have highlighted that consistent daily use can enhance effectiveness, with one suggesting taking the supplement for a week in the correct dosages to see improvements without needing antibiotics Read Review. While positive results are noted by many, there are also reports of varying experiences, with some individuals not feeling any improvement at all Read Review. Ultimately, it seems that while many users have found success within weeks, results can vary greatly.
Quercetin, a natural flavonoid, shows promising potential as a supplement for sinusitis based on several research studies. One study demonstrated that quercetin administration after inducing inflammation in a rat model significantly reduced inflammatory markers such as TNF-α and IL-6 in nasal and lung tissues [1]. This indicates its capability to alleviate the inflammation commonly associated with sinusitis. Furthermore, quercetin has been shown to enhance mucus clearance by improving chloride secretion and ciliary beat frequency in sinonasal cells, which could be beneficial for those suffering from chronic rhinosinusitis [2].
In addition to its anti-inflammatory properties, quercetin appears to modulate inflammatory cytokine production in human mast cells, reducing key signals that contribute to inflammation [3]. This suggests that quercetin could be a valuable natural option for managing sinusitis, particularly in its inflammatory component. While these findings are encouraging, it’s essential to consider that most studies are preliminary and often conducted in vitro or in animal models. Therefore, further research, particularly human clinical trials, would help in establishing definitive efficacy and safety for quercetin as a sinusitis supplement.
Many users have reported notable improvements in their symptoms after using this supplement for sinusitis. For instance, one user shared that their chronic nasal congestion markedly improved, allowing for better breathing and sleeping after just the first tablet Read Review. Another individual indicated that they no longer experienced morning congestion and headaches associated with rhinitis after consistent use over a month Read Review. This supplement has also helped individuals combat not only sinusitis but also related conditions like asthma and allergies, showcasing its versatility as a remedy Read Review.
While many users have praised the product for reducing their symptoms—some have reported a decrease in stress levels along with physical improvements in nasal congestion Read Review—it is worth noting that individual responses can vary significantly. Some users did not experience any positive effects and even reported adverse reactions Read Review. Thus, while the anecdotal evidence suggests a tendency toward symptom relief for many users, outcomes can differ, highlighting the importance of personal experience in evaluating the effectiveness of this supplement.
Based on user reviews, many individuals have reported positive experiences when combining this supplement with other products to manage sinusitis. For example, one user noted that they achieved remarkable results by taking this supplement alongside NAC, claiming to have never experienced such positive outcomes after years of dealing with sinusitis Read Review. Another reviewer mentioned using freeze-dried stinging nettle and inhaling eucalyptus mixed with hot water for additional relief, reinforcing the idea that combining therapies can enhance overall results for sinus issues Read Review.
Additionally, the reviews indicate that some users found this supplement effective as a natural alternative to conventional medications, suggesting that integrating it into a broader regimen can be beneficial. For instance, one user emphasized the importance of taking the supplement with food to maximize its benefits, highlighting a strategic approach in combining it with dietary considerations Read Review. However, it is worth noting that individual responses can vary significantly, with some users experiencing little to no benefit even when used in conjunction with other treatments Read Review. Ultimately, while many users advocate for combining this supplement with others for enhanced effectiveness, personal experimentation is vital for determining what works best.
Based on user reviews, there seems to be a consensus that the right dosage of Quercetin for treating sinusitis can vary among individuals, but many users suggest starting with one tablet and adjusting as needed. For instance, one user reported starting with one tablet twice daily for chronic sinusitis and experienced significant relief, eventually increasing to two tablets twice daily during more severe episodes Read Review. Others indicated that taking the supplement consistently over time, often alongside food, can lead to improved outcomes for managing symptoms Read Review.
Some users noted that beginning with a single tablet daily and gradually increasing the dose might be beneficial, helping the body adjust without adverse effects Read Review. Additionally, reviews suggest a combination of Quercetin with bromelain is particularly effective in alleviating sinusitis symptoms Read Review. Overall, while there’s no one-size-fits-all dose, a starting point of one tablet a day appears common, with flexibility to increase based on individual responses and symptom severity.
7.5
Improved nasal congestion
33 people found this helpful
I started taking one tablet twice daily for my chronic sinusitis. After a month, my headaches from rhinitis faded, and I no longer wake up with a clogged nose. When my rhinitis was severe, I took two tablets twice a day, and I felt progressively better. I intend to continue this.
9
Game-changer
2 people found this helpful
As someone with recurring sinusitis, quercetin with bromelain has transformed my experience. Within weeks, I noticed significant relief from sinus congestion and inflammation. This product is easy to take, plant-based, and has become an essential part of my routine. I highly recommend it for anyone facing sinus or respiratory issues.
9
Sinusitis remedy
3 people found this helpful
I use this supplement for sinusitis. If taken properly in the morning and evening for a week, it can effectively heal the condition without resorting to antibiotics. This has spared me from hospital visits and the unpleasant side effects of antibiotics.
2
No effect noted
4 people found this helpful
I noticed zero effect on my sinusitis. This product did not alleviate my nasal congestion caused by allergies.
9
Good for seasonal allergies
30 people found this helpful
I struggled with a stuffy nose due to seasonal allergies, but after trying this product, I was amazed at how effective the first tablet was. That night I could breathe easily and sleep well. Quercetin is a valuable alternative for those looking to avoid medications. Highly recommend it for sinusitis!
9
Skin and allergy relief
119 people found this helpful
Quercetin and bromelain are potent natural ingredients that help alleviate allergic and inflammatory disorders, including sinusitis. They relieve asthma symptoms, promote phlegm elimination, and reduce inflammation in cartilage and joints. As someone with arthritis and allergies, Quercetin has been a lifesaver for me, and I take it regularly. I highly recommend it!
8
Nasal congestion relief
6 people found this helpful
I bought this due to my chronic sinusitis and was intrigued by the reviews. Since starting, my nasal congestion has improved, and my stress levels have decreased. I hope it also assists with my allergic rhinitis during pollen season.
9
Significant effect noted
5 people found this helpful
I started taking this supplement during the pandemic and have been consistently using it ever since. When my chronic sinusitis flares up, I take it alongside NAC, and I’ve never experienced such positive results in my ten years of battling sinusitis. I'm very pleased with the effects.
7.5
Works with combination
5 people found this helpful
This works well when taken with freeze-dried stinging nettle for allergies. I also use eucalyptus in hot water to inhale for my sinusitis.
9
Natural antihistamine
5 people found this helpful
I cannot emphasise enough how excellent this product is. For those needing antihistamines for persistent allergies, this is a great natural alternative, effectively addressing my sinusitis and eye allergies from pollution. Just ensure to take it with food.
6
Moderate sinusitis relief
17 people found this helpful
I took this review from the 120-capsule bottle. I initially experienced headaches but have since adjusted. With sinusitis, my symptoms improved by about 30–40% after taking the supplement. I recommend starting with one tablet a day for a week to adapt, then increasing the dosage as needed.
7.5
Anti-allergy effect
4 people found this helpful
I have been taking quercetin for 2.5 years after being diagnosed with AIDS, as prescribed by my doctor. It also has the added benefit of reducing allergies. I took it from July to September to combat ambrosia reactions, and it helped tremendously. Additionally, it contains bromelain, which aids in the fight against chronic sinusitis. I really appreciate the quality of this brand. The capsules are small, with a neutral taste, making it an essential dietary supplement for me.
9
Quercetin reduces sinus inflammation
Quercetin attenuates naso-sinusal inflammation and inflammatory response in lungs and brain on an experimental model of acute rhinosinusitis in rats.
This study explored how quercetin may help reduce inflammation associated with sinusitis using a rat model. We observed that introducing lipopolysaccharides (LPS) caused significant inflammation in nasal and sinus areas, as well as in the lungs and brain.
When we administered quercetin after the LPS treatment, it notably decreased inflammatory markers like TNF-α and IL-6. The results indicated reduced inflammation in nasal and lung tissues, showcasing quercetin's potential benefits. However, while there were encouraging findings, its effects on brain inflammation were more limited.
8
Quercetin enhances mucus transport
Quercetin increases cystic fibrosis transmembrane conductance regulator-mediated chloride transport and ciliary beat frequency: therapeutic implications for chronic rhinosinusitis.
We explored how quercetin might help sinusitis by boosting chloride secretion and improving ciliary beat frequency in cultured sinonasal cells. In our analysis, this compound showed notable ability to enhance these functions, suggesting it could promote better mucus clearance from the sinuses.
The study involved primary cultures of human and murine sinonasal epithelial cells and demonstrated quercetin's effectiveness in increasing chloride transport. This implies potential therapeutic benefits for individuals suffering from chronic rhinosinusitis.
7
Quercetin reduces inflammation in sinusitis
Quercetin inhibits expression of inflammatory cytokines through attenuation of NF-kappaB and p38 MAPK in HMC-1 human mast cell line.
We explored how quercetin affects sinusitis by examining its impact on human mast cells. Specifically, we focused on the expression of inflammatory cytokines after stimulating the cells.
Quercetin showed promise by reducing the gene expression and production of key inflammatory signals like TNF-alpha and IL-6. It did this by dampening the activation of NF-kappaB and p38 MAPK pathways, both crucial for inflammation.
This suggests that quercetin may be beneficial for managing conditions like sinusitis linked to mast cell activity.
References
Tiboc-Schnell CN, Filip GA, Man SC, Decea N, Moldovan R, et al. Quercetin attenuates naso-sinusal inflammation and inflammatory response in lungs and brain on an experimental model of acute rhinosinusitis in rats. J Physiol Pharmacol. 2020;71. doi:10.26402/jpp.2020.4.03
Zhang S, Smith N, Schuster D, Azbell C, Sorscher EJ, et al. Quercetin increases cystic fibrosis transmembrane conductance regulator-mediated chloride transport and ciliary beat frequency: therapeutic implications for chronic rhinosinusitis. Am J Rhinol Allergy. 2011;25:307. doi:10.2500/ajra.2011.25.3643
Min YD, Choi CH, Bark H, Son HY, Park HH, et al. Quercetin inhibits expression of inflammatory cytokines through attenuation of NF-kappaB and p38 MAPK in HMC-1 human mast cell line. Inflamm Res. 2007;56:210.