Overview
SCIENTIFIC SCORE
Moderately Effective
Based on 9 Researches
8.1
USERS' SCORE
Good
Based on 3 Reviews
8.4
Top Medical Research Studies
8
Zinc may alleviate anxiety symptoms
We explored the connection between zinc intake and anxiety in adults through a systematic review of nine original studies. Two of these studies looked at how zinc consumption impacts anxiety, while the other seven focused on the relationship between serum zinc levels and anxiety symptoms. Our analysis included studies published in English within peer-reviewed journals, ensuring a solid foundation for understanding this potential link.
What we discovered was quite illuminating. The data indicated that individuals experiencing anxiety often had lower levels of zinc in their serum compared to those who did not suffer from anxiety. Additionally, we observed an inverse association between zinc intake and anxiety levels. This suggests that higher consumption of zinc may contribute to reduced anxiety symptoms.
In conclusion, the evidence points towards zinc playing a positive role in treating anxiety, although we acknowledge some limitations in the available studies. This means zinc supplementation could be a beneficial strategy for those looking to manage their anxiety, but more research is needed to confirm these findings and understand the underlying mechanisms better.
What we discovered was quite illuminating. The data indicated that individuals experiencing anxiety often had lower levels of zinc in their serum compared to those who did not suffer from anxiety. Additionally, we observed an inverse association between zinc intake and anxiety levels. This suggests that higher consumption of zinc may contribute to reduced anxiety symptoms.
In conclusion, the evidence points towards zinc playing a positive role in treating anxiety, although we acknowledge some limitations in the available studies. This means zinc supplementation could be a beneficial strategy for those looking to manage their anxiety, but more research is needed to confirm these findings and understand the underlying mechanisms better.
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8
Vitamin C alleviates anxiety in autism
We set out to explore how vitamin C influences anxiety-like behaviors in a model of autism caused by valproic acid (VPA). In our study, we used fourteen female rats that underwent specific treatments to induce autism in their offspring. After a period of observation, we treated male pups with daily injections of vitamin C for four weeks. Then, we assessed their behavior to see if there were any changes in anxiety levels.
Our findings suggested that vitamin C significantly reduced anxiety-like behaviors in these rats. This outcome is particularly promising considering that autism often brings associated anxiety. By measuring various brain oxidative stress markers, we also noted improvements in mental functioning and motor skills after vitamin C treatment. Overall, our work underscores the potential benefits of vitamin C as a supportive treatment for anxiety-related issues in autism, indicating a pathway for future research and therapeutic strategies.
Our findings suggested that vitamin C significantly reduced anxiety-like behaviors in these rats. This outcome is particularly promising considering that autism often brings associated anxiety. By measuring various brain oxidative stress markers, we also noted improvements in mental functioning and motor skills after vitamin C treatment. Overall, our work underscores the potential benefits of vitamin C as a supportive treatment for anxiety-related issues in autism, indicating a pathway for future research and therapeutic strategies.
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7
Zinc alleviates acrylamide-induced anxiety
We explored the effects of zinc treatment on anxiety caused by exposure to acrylamide, a harmful chemical found in some foods that can lead to cognitive decline and emotional distress. In our study, twenty male Wistar rats were divided into four groups; one group received water, while the other groups were given a daily oral dose of acrylamide.
Among those exposed to acrylamide, some were treated with low and high doses of zinc for eight weeks. We observed that zinc significantly improved anxiety-like behavior in the treated groups. This suggests that zinc acts not only as a protector against cognitive impairment but also helps in alleviating anxiety symptoms associated with acrylamide exposure.
Furthermore, zinc demonstrated antioxidant and anti-inflammatory effects, which could contribute to its ability to improve mood and mental function. Overall, zinc emerged as a promising contender in mitigating anxiety and cognitive challenges posed by acrylamide, leading to better mental clarity and emotional well-being.
Among those exposed to acrylamide, some were treated with low and high doses of zinc for eight weeks. We observed that zinc significantly improved anxiety-like behavior in the treated groups. This suggests that zinc acts not only as a protector against cognitive impairment but also helps in alleviating anxiety symptoms associated with acrylamide exposure.
Furthermore, zinc demonstrated antioxidant and anti-inflammatory effects, which could contribute to its ability to improve mood and mental function. Overall, zinc emerged as a promising contender in mitigating anxiety and cognitive challenges posed by acrylamide, leading to better mental clarity and emotional well-being.
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Most Useful Reviews
7.5
Reduced anxiety effectively
2 people found this helpful
The best multi-vitamin I have taken. Rainbow Light has been a great gap filler for my busy schedule when I can't have smoothies. I have noticed a difference in my anxieties, as my energy levels have increased, allowing me to get through the entire day without crashing after dinner. I've also become a bit more frisky with my wife lately, which is a nice perk. I dropped about 10 lbs without trying, which might be due to the ingredients that help my mood and stress. We eat healthily and take other supplements, but Rainbow Light is a great nutritional base that I recommend.
Read More
9
Enhanced focus daily
1 people found this helpful
The natural ingredients in this 1-a-day pill are phenomenal compared to many other brands I've tried. Since I started taking Rainbow Light multis in 2016, I have found the diverse and effective ingredients have made me more focused and motivated, while also reducing soreness and anxiety. This product truly delivers, and I would recommend it.
Read More
7.5
Aids blood sugar regulation
1 people found this helpful
This multi-vitamin really helps with my low blood sugar issues. I exercise regularly and was experiencing severe hunger-related anxiety if meals were missed. Since taking these vitamins daily, I no longer experience that anxiety or hunger swing. They work exceptionally well for me.
Read More
Medical Researches
SCIENTIFIC SCORE
Moderately Effective
Based on 9 Researches
8.1
- All Researches
9
We aimed to understand how zinc chloride may help reduce anxiety, particularly when combined with diazepam. In our study, we organized Wistar albino rats into five groups, with each group receiving different combinations of zinc chloride and diazepam. The dosages included two different levels of diazepam (1 and 2 mg/kg) paired with a consistent dose of zinc chloride (10 mg/kg).
To assess the anxiety levels of the rats, we employed four established models: the Elevated Plus Maze, the hole board, the light and dark box, and the mirror chamber. Our observations indicated that when combined, zinc chloride and diazepam produced more potent anxiolytic effects compared to when either treatment was used alone. This suggests a possible synergistic effect that could enhance anxiety relief.
Overall, we found that zinc chloride, especially when combined with diazepam, can significantly improve anxiety outcomes in these animal models. This research opens the door to further studies on zinc's role in anxiety management and its potential as a supplementary treatment option alongside traditional medications.
To assess the anxiety levels of the rats, we employed four established models: the Elevated Plus Maze, the hole board, the light and dark box, and the mirror chamber. Our observations indicated that when combined, zinc chloride and diazepam produced more potent anxiolytic effects compared to when either treatment was used alone. This suggests a possible synergistic effect that could enhance anxiety relief.
Overall, we found that zinc chloride, especially when combined with diazepam, can significantly improve anxiety outcomes in these animal models. This research opens the door to further studies on zinc's role in anxiety management and its potential as a supplementary treatment option alongside traditional medications.
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9
Zinc reduces anxiety in treatment
In a recent study, we investigated how zinc supplementation could impact anxiety levels among patients undergoing methadone maintenance treatment for opioid use disorder. The research involved a randomized controlled trial with 68 participants. We divided them into two groups: one received zinc supplements along with their usual methadone treatment, while the other group only received methadone.
Our findings revealed some encouraging results regarding anxiety reduction. Specifically, we noted a significant decrease in anxiety levels among those who took zinc, with a marked difference when compared to the control group. This was assessed using the Depression, Anxiety, and Stress Scale 21 (DASS-21), where we observed a notable reduction in anxiety scores following the treatment period.
Overall, it appears that zinc supplementation may contribute positively to reducing anxiety in this particular patient demographic. However, since zinc was combined with methadone treatment, it's essential we approach these findings with caution and encourage further research to clarify the role of zinc supplementation alone.
Our findings revealed some encouraging results regarding anxiety reduction. Specifically, we noted a significant decrease in anxiety levels among those who took zinc, with a marked difference when compared to the control group. This was assessed using the Depression, Anxiety, and Stress Scale 21 (DASS-21), where we observed a notable reduction in anxiety scores following the treatment period.
Overall, it appears that zinc supplementation may contribute positively to reducing anxiety in this particular patient demographic. However, since zinc was combined with methadone treatment, it's essential we approach these findings with caution and encourage further research to clarify the role of zinc supplementation alone.
Read More
8
Vitamin C alleviates anxiety in autism
We set out to explore how vitamin C influences anxiety-like behaviors in a model of autism caused by valproic acid (VPA). In our study, we used fourteen female rats that underwent specific treatments to induce autism in their offspring. After a period of observation, we treated male pups with daily injections of vitamin C for four weeks. Then, we assessed their behavior to see if there were any changes in anxiety levels.
Our findings suggested that vitamin C significantly reduced anxiety-like behaviors in these rats. This outcome is particularly promising considering that autism often brings associated anxiety. By measuring various brain oxidative stress markers, we also noted improvements in mental functioning and motor skills after vitamin C treatment. Overall, our work underscores the potential benefits of vitamin C as a supportive treatment for anxiety-related issues in autism, indicating a pathway for future research and therapeutic strategies.
Our findings suggested that vitamin C significantly reduced anxiety-like behaviors in these rats. This outcome is particularly promising considering that autism often brings associated anxiety. By measuring various brain oxidative stress markers, we also noted improvements in mental functioning and motor skills after vitamin C treatment. Overall, our work underscores the potential benefits of vitamin C as a supportive treatment for anxiety-related issues in autism, indicating a pathway for future research and therapeutic strategies.
Read More
8
Zinc's potential impact on anxiety
Our study delved into how the intranasal administration of a chelate complex involving zinc arginyl-glycinate and alpha-glutamyl-tryptophan dipeptide influences anxiety and related behaviors. We utilized various rodent models, including Wistar rats and different types of mice to assess behavioral changes and levels of key brain chemicals.
We observed that intranasal delivery had noticeable effects, particularly in mice. Those given alpha-glutamyl-tryptophan showed reduced anxiety and less depressive-like behavior during acute trials. The promising results hint that this method of administration could serve as an effective new approach for treating anxiety.
Despite these findings, it's important to note that because zinc was administered in combination with other compounds, we cannot isolate the effects of zinc alone on anxiety. Nonetheless, this research sets the stage for further pre-clinical studies on how these treatments may possibly serve as anxiolytics or antidepressants.
We observed that intranasal delivery had noticeable effects, particularly in mice. Those given alpha-glutamyl-tryptophan showed reduced anxiety and less depressive-like behavior during acute trials. The promising results hint that this method of administration could serve as an effective new approach for treating anxiety.
Despite these findings, it's important to note that because zinc was administered in combination with other compounds, we cannot isolate the effects of zinc alone on anxiety. Nonetheless, this research sets the stage for further pre-clinical studies on how these treatments may possibly serve as anxiolytics or antidepressants.
Read More
8
We investigated if a combination of zinc and selenium could help reduce anxiety and improve memory in rats affected by a transient ischemic attack (TIA), also known as a minor stroke. This study involved giving male Wistar rats a preventative dose of zinc prior to the stroke and a therapeutic dose of selenium afterward. Our findings indicated that, while zinc alone was part of a broader treatment, the combined approach did yield positive effects in managing anxiety-like behaviors, alongside reducing memory loss and signs of depression over the long term.
It is important to highlight that while we observed improvements in behavior and cognitive functions, the specific effects of zinc on anxiety were not isolated or thoroughly examined. This raises an interesting point about the need for further research that targets zinc’s individual impact on anxiety management. Nevertheless, in combination, zinc and selenium appeared to offer long-term neuroprotective effects that could be promising for future treatments in similar contexts.
It is important to highlight that while we observed improvements in behavior and cognitive functions, the specific effects of zinc on anxiety were not isolated or thoroughly examined. This raises an interesting point about the need for further research that targets zinc’s individual impact on anxiety management. Nevertheless, in combination, zinc and selenium appeared to offer long-term neuroprotective effects that could be promising for future treatments in similar contexts.
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User Reviews
USERS' SCORE
Good
Based on 3 Reviews
8.4
- All Reviews
- Positive Reviews
- Negative Reviews
7.5
Reduced anxiety effectively
2 people found this helpful
The best multi-vitamin I have taken. Rainbow Light has been a great gap filler for my busy schedule when I can't have smoothies. I have noticed a difference in my anxieties, as my energy levels have increased, allowing me to get through the entire day without crashing after dinner. I've also become a bit more frisky with my wife lately, which is a nice perk. I dropped about 10 lbs without trying, which might be due to the ingredients that help my mood and stress. We eat healthily and take other supplements, but Rainbow Light is a great nutritional base that I recommend.
Read More
9
Enhanced focus daily
1 people found this helpful
The natural ingredients in this 1-a-day pill are phenomenal compared to many other brands I've tried. Since I started taking Rainbow Light multis in 2016, I have found the diverse and effective ingredients have made me more focused and motivated, while also reducing soreness and anxiety. This product truly delivers, and I would recommend it.
Read More
7.5
Aids blood sugar regulation
1 people found this helpful
This multi-vitamin really helps with my low blood sugar issues. I exercise regularly and was experiencing severe hunger-related anxiety if meals were missed. Since taking these vitamins daily, I no longer experience that anxiety or hunger swing. They work exceptionally well for me.
Read More
Frequently Asked Questions
No FAQs are available for this product and symptom.
References
- Tarahomi P, Arab M, Seyedinia SA, Rahmani M, Rashidy-Pour A, et al. Vitamin C and Gallic Acid Ameliorate Motor Dysfunction, Cognitive Deficits, and Brain Oxidative Stress in a Valproic Acid-Induced Model of Autism. Brain Behav. 2025;15:e70262. doi:10.1002/brb3.70262
- Ajibare AJ, Akintoye OO, Oriowo OA, Asuku AO, Oriyomi IA, et al. Zinc Ameliorates Acrylamide-Induced Cognitive Impairment in Male Wistar Rats: Modulation of Oxidative Stress, Neuro-inflammation, and Neurotrophic Pathways. Biol Trace Elem Res. 2024. doi:10.1007/s12011-024-04490-0
- Apryatin S, Lopachev A, Zhukov I, Efimova E, Apryatina V. BEHAVIORAL AND NEUROCHEMICAL CHANGES DURING INTRANASAL ADMINISTRATION OF ALPHA-GLUTAMYL-TRYPTOPHAN AND CHELATE COMPLEX OF ZINC ARGINYL-GLYCINATE ON MONOAMINE SYSTEMS DYSFUNCTIONS KNOCK-OUT MODELS. Georgian Med News. 2024.
- Naik VV, Desai VH, Noronha S. Synergistic anxiolytic efficacy exploring the combined effects of diazepam and zinc chloride in wistar albino rats. Drug Res (Stuttg). 2024;74:220. doi:10.1055/a-2308-9192
- Tomas-Sanchez C, Blanco-Alvarez VM, Gonzalez-Barrios JA, Martinez-Fong D, Soto-Rodriguez G, et al. Prophylactic zinc and therapeutic selenium administration in adult rats prevents long-term cognitive and behavioral sequelae by a transient ischemic attack. Heliyon. 2024;10:e30017. doi:10.1016/j.heliyon.2024.e30017
- Sameei P, Fatehfar S, Abdollahzadeh N, Chodari L, Saboory E, et al. The effects of forced exercise and zinc supplementation during pregnancy on prenatally stress-induced behavioral and neurobiological consequences in adolescent female rat offspring. Dev Psychobiol. 2023;65:e22411. doi:10.1002/dev.22411
- Azargoonjahromi A. A systematic review of the association between zinc and anxiety. Nutr Rev. 2024;82:612. doi:10.1093/nutrit/nuad076
- Hamdi E, Muñiz-Gonzalez AB, Hidouri S, Bermejo AM, Sakly M, et al. Prevention of neurotoxicity and cognitive impairment induced by zinc nanoparticles by oral administration of saffron extract. J Anim Physiol Anim Nutr (Berl). 2023;107:1473. doi:10.1111/jpn.13848
- Amini Z, HeidariFarsani E. Investigating the effect of zinc supplementation on probability of relapse and mental health in patients with opioid use disorder undergoing methadone maintenance treatment. Subst Abuse Treat Prev Policy. 2023;18:1. doi:10.1186/s13011-023-00514-5
