Overview

SCIENTIFIC SCORE
Possibly Effective
Based on 3 Researches
7.3
USERS' SCORE
Good
Based on 6 Reviews
8.9

Top Medical Research Studies

We investigated how adding vitamin C to milk influences the growth and health of young calves, particularly those experiencing diarrhea. The study involved 48 Holstein calves, which were sorted into two groups based on their health status: healthy calves and those with diarrhea. Each calf was fed the same amount of pasteurized milk and monitored until they reached 74 days of age.

Calves that received vitamin C showed an impressive increase in weight by weaning—74.3 kg compared to 72.2 kg for those without vitamin C. Additionally, calves treated with vitamin C demonstrated improved blood antioxidant levels, suggesting better overall health. Notably, calves suffering from diarrhea benefitted significantly from the vitamin C, needing fewer days of medication for treatment compared to those who did not receive the supplement.

The research highlights that vitamin C can play a critical role in supporting the health of calves during episodes of diarrhea. This is especially relevant for those that faced even mild cases early in life, as they seemed to gain the most benefits from the supplementation. Overall, it appears that vitamin C can positively impact both growth and health in calves suffering from diarrhea.
Read More
9
Zinc oxide mitigates diarrhea impacts
We explored how zinc oxide (ZnO), often used as a feed additive, affects diarrhea and gut health in piglets infected with the ETEC K88 strain. Through careful observation, we found that piglets suffering from this infection exhibited significantly increased fecal scores compared to those not affected. The ETEC K88 strain harms the small intestine, leading to a loss of villus height and a decrease in important antioxidant activities.

Our findings revealed that ZnO administration counteracts these negative effects effectively. It not only improved the overall health of the intestine but also enhanced its ability to combat oxidative stress. We also observed a balanced restoration of gut microbiota, as ZnO helped normalize the populations of certain beneficial bacteria altered by the infection.

In summary, our study indicates that ZnO can play a vital role in easing diarrhea in piglets infected with ETEC K88 by reducing intestinal damage, supporting antioxidative defenses, and restoring healthy gut flora.
Read More
4
Ranitidine outperforms probiotics
We explored the effectiveness of a short course of oral ranitidine compared to probiotics in treating toddler's diarrhea. In a carefully designed trial, 40 participants were randomly assigned to three groups: those receiving ranitidine, those taking probiotics with vitamin C, and a placebo group.

Our main focus was to see if any of these options could reduce the frequency of stools and improve their consistency after ten days of treatment. While the results showed that oral ranitidine outperformed probiotics in managing toddler's diarrhea, the role of vitamin C was less clear.

It's important to highlight that in this study, the probiotics were combined with vitamin C, making it difficult to isolate its individual effects on diarrhea. Overall, we found that ranitidine was more effective than the probiotics, but we can't confidently say how vitamin C contributed to the outcomes. We recommend further studies to investigate these treatments in more detail.
Read More

Most Useful Reviews

9.5
Best probiotic for IBS-D
FABULOUS PRODUCT. I suffer from IBS and have tried every expensive probiotic available. For IBS-D (diarrhoea), this product excels beyond the rest! After a few weeks, I could reduce my intake to every other day while maintaining its effectiveness. You must find what suits you, but this one has outperformed others and has truly helped manage my IBS symptoms.
Read More
9.5
Saved my cat
Works in an emergency for diarrhea (for my cat) -- WITHOUT FILLERS!!! Renew Life has made a wonderful product devoid of magnesium stearate or ascorbyl palmitate, which are problematic for cats. When my cat's diarrhoea became severe, I was desperate. Having this on hand potentially saved her life, stabilising what could have been a life-threatening situation. I am grateful that this product lives up to the hype and is a crucial item in any pet lover's emergency kit. It’s also great that Renew Life offers products free from problematic fillers.
Read More
10
Life changing experience
No more digestive issues! I've suffered from IBS for years, with a sensitive digestive system. After researching various brands, I chose this probiotic. Within one week, my diarrhoea improved significantly. After a month, my digestive health returned to normal, with 100% improvement. I now take it every other day without worrying about unexpected trips to the bathroom. It's been a life-changing experience, allowing me to eat freely again. I have no plans to stop using it.
Read More

Medical Researches

SCIENTIFIC SCORE
Possibly Effective
Based on 3 Researches
7.3
  • All Researches
We investigated how adding vitamin C to milk influences the growth and health of young calves, particularly those experiencing diarrhea. The study involved 48 Holstein calves, which were sorted into two groups based on their health status: healthy calves and those with diarrhea. Each calf was fed the same amount of pasteurized milk and monitored until they reached 74 days of age.

Calves that received vitamin C showed an impressive increase in weight by weaning—74.3 kg compared to 72.2 kg for those without vitamin C. Additionally, calves treated with vitamin C demonstrated improved blood antioxidant levels, suggesting better overall health. Notably, calves suffering from diarrhea benefitted significantly from the vitamin C, needing fewer days of medication for treatment compared to those who did not receive the supplement.

The research highlights that vitamin C can play a critical role in supporting the health of calves during episodes of diarrhea. This is especially relevant for those that faced even mild cases early in life, as they seemed to gain the most benefits from the supplementation. Overall, it appears that vitamin C can positively impact both growth and health in calves suffering from diarrhea.
Read More
9
Zinc oxide mitigates diarrhea impacts
We explored how zinc oxide (ZnO), often used as a feed additive, affects diarrhea and gut health in piglets infected with the ETEC K88 strain. Through careful observation, we found that piglets suffering from this infection exhibited significantly increased fecal scores compared to those not affected. The ETEC K88 strain harms the small intestine, leading to a loss of villus height and a decrease in important antioxidant activities.

Our findings revealed that ZnO administration counteracts these negative effects effectively. It not only improved the overall health of the intestine but also enhanced its ability to combat oxidative stress. We also observed a balanced restoration of gut microbiota, as ZnO helped normalize the populations of certain beneficial bacteria altered by the infection.

In summary, our study indicates that ZnO can play a vital role in easing diarrhea in piglets infected with ETEC K88 by reducing intestinal damage, supporting antioxidative defenses, and restoring healthy gut flora.
Read More
4
Ranitidine outperforms probiotics
We explored the effectiveness of a short course of oral ranitidine compared to probiotics in treating toddler's diarrhea. In a carefully designed trial, 40 participants were randomly assigned to three groups: those receiving ranitidine, those taking probiotics with vitamin C, and a placebo group.

Our main focus was to see if any of these options could reduce the frequency of stools and improve their consistency after ten days of treatment. While the results showed that oral ranitidine outperformed probiotics in managing toddler's diarrhea, the role of vitamin C was less clear.

It's important to highlight that in this study, the probiotics were combined with vitamin C, making it difficult to isolate its individual effects on diarrhea. Overall, we found that ranitidine was more effective than the probiotics, but we can't confidently say how vitamin C contributed to the outcomes. We recommend further studies to investigate these treatments in more detail.
Read More

User Reviews

USERS' SCORE
Good
Based on 6 Reviews
8.9
  • All Reviews
  • Positive Reviews
  • Negative Reviews
9.5
Best probiotic for IBS-D
FABULOUS PRODUCT. I suffer from IBS and have tried every expensive probiotic available. For IBS-D (diarrhoea), this product excels beyond the rest! After a few weeks, I could reduce my intake to every other day while maintaining its effectiveness. You must find what suits you, but this one has outperformed others and has truly helped manage my IBS symptoms.
Read More
9.5
Saved my cat
Works in an emergency for diarrhea (for my cat) -- WITHOUT FILLERS!!! Renew Life has made a wonderful product devoid of magnesium stearate or ascorbyl palmitate, which are problematic for cats. When my cat's diarrhoea became severe, I was desperate. Having this on hand potentially saved her life, stabilising what could have been a life-threatening situation. I am grateful that this product lives up to the hype and is a crucial item in any pet lover's emergency kit. It’s also great that Renew Life offers products free from problematic fillers.
Read More
10
Life changing experience
No more digestive issues! I've suffered from IBS for years, with a sensitive digestive system. After researching various brands, I chose this probiotic. Within one week, my diarrhoea improved significantly. After a month, my digestive health returned to normal, with 100% improvement. I now take it every other day without worrying about unexpected trips to the bathroom. It's been a life-changing experience, allowing me to eat freely again. I have no plans to stop using it.
Read More
9.5
Miracle solution
Knocked out antibiotic upset. After over two months on antibiotics, I experienced severe diarrhoea, which made me think of c-diff. I tried spring valley probiotics with no success and eventually turned to ReNew Life ultimate Flora probiotic. After just five days, I experienced a miraculous change. I can't guarantee everyone will have the same experience, but this product effectively resolved my diarrhoea, and I feel much better now.
Read More
10
Diarrhea gone
Got rid of diarrhoea. Within a week, this product eliminated the diarrhoea I had been struggling with for months.
Read More

Frequently Asked Questions

No FAQs are available for this product and symptom.

References

  1. Zakariya MR, Ghasemi E, Hashemzadeh F, Ghorbani GR, Ahmadi F. Does vitamin C supplementation in milk improve growth and health of diarrheic calves?. Prev Vet Med. 2024;224:106122. doi:10.1016/j.prevetmed.2024.106122
  2. Uwaezuoke SN, Ndu IK, Eneh CI, Anusiem CA, Ayuk AC. A short course of oral ranitidine as a novel treatment for toddler's diarrhea: a parallel-group randomized controlled trial. BMC Pediatr. 2020;20:380. doi:10.1186/s12887-020-02267-7
  3. Zhang Y, Liu J, Li M, Dong Y, Li Z, et al. Zinc Oxide Administration Relieves the Diarrhea of ETEC K88-Infected Piglets by Reducing Ileal Apoptosis and Maintaining Gut Microbial Balance. Vet Sci. 2025;12. doi:10.3390/vetsci12020115
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