Overview
SCIENTIFIC SCORE
Moderately Effective
Based on 7 Researches
8.6
USERS' SCORE
Good
Based on 3 Reviews
8.8
Top Medical Research Studies
9.5
We explored the potential of a new composite hydrogel that combines probiotics and fucoidan to aid oral ulcer healing. This study focused on how this hydrogel adheres to tissue and releases probiotics effectively. Remarkably, the hydrogels showed better therapeutic results compared to standard oral ulcer patches by promoting faster cell migration and healing.
Overall, this innovative approach suggests a promising future for treating oral ulcers more effectively than traditional methods.
Overall, this innovative approach suggests a promising future for treating oral ulcers more effectively than traditional methods.
Read More
9
We explored the effects of delivering human epidermal growth factor (EGF) through a probiotic strain of E. coli to help treat intestinal ulcers. The study showed that treatment with EGF-EcN not only alleviated ulcers but also helped in restoring damaged barrier layers in the gut. We observed that this method promotes the recovery of important cell types and strengthens mucosal integrity. Importantly, the probiotic did not worsen any cancerous conditions related to ulcerative colitis. Overall, our findings suggest that using probiotics to deliver helpful proteins like EGF can be a safe and effective strategy for managing gastrointestinal ulcers.
Read More
9
We recently explored the protective effects of a specific probiotic called Bifidobacterium breve (Bif195) on small-intestinal damage caused by acetylsalicylic acid (ASA), a common pain reliever. In a randomized, double-blind trial involving 75 healthy volunteers, participants took daily doses of either Bif195 or a placebo for eight weeks.
The results were promising! Those who took Bif195 experienced significantly lower levels of intestinal damage and fewer ulcers compared to the placebo group. Importantly, the use of Bif195 was well tolerated with minimal adverse events reported.
The results were promising! Those who took Bif195 experienced significantly lower levels of intestinal damage and fewer ulcers compared to the placebo group. Importantly, the use of Bif195 was well tolerated with minimal adverse events reported.
Read More
Most Useful Reviews
10
Life-saving probiotics
I was struggling to eat normal portions due to ulcer symptoms for months. By chance, my brother had probiotics sent to me from abroad. I was losing weight rapidly and thought I might need surgery. Thankfully, after trying a bottle of 30, I was able to eat almost anything within two weeks. I started gaining weight again, and whatever was causing my ulcer symptoms disappeared! I was also experiencing constipation, which was resolved. I'm grateful for my brother's timely delivery. Now, I take them every other day and plan to continue using them as long as possible!
Read More
9
Stomach issues resolved
Renew Life Ultimate Flora Extra Care Probiotic 50 Billion is a fantastic product, and I highly recommend it. As I've aged, I've aimed for a healthier lifestyle and realised I could benefit from probiotics due to past stomach issues, including an ulcer. After a few days of use, I was convinced. I've continued using it daily, and my stomach issues are resolved. Who knew adding positive bacteria to my system could have such a significant impact? I highly recommend this product.
Read More
9.5
Relief from ulcers
In my experience, it's more than a small miracle. I've tried various probiotics over the years, and while this one is costly, it's worth it. For over a decade, I've battled digestive issues, and though other brands helped somewhat, their effectiveness fluctuated. I hesitated to invest in something seemingly similar to what I previously used, but I'm so pleased I did! My immune system often requires antibiotics, which disrupt my digestion and lead to painful mouth ulcers. Since using Renew Life Ultimate Flora Extra Care, I haven't experienced mouth ulcers during antibiotic use, and my digestive issues now emerge later. It's a relief knowing I can recover and enjoy my favourite foods without worry.
Read More
Medical Researches
SCIENTIFIC SCORE
Moderately Effective
Based on 7 Researches
8.6
- All Researches
9.5
We constructed acute gastric ulcer models in mice by administering hydrochloric acid and ethanol, then introduced white jade snail secretion (WJSS) through gastric infusion. Our findings revealed that WJSS significantly reduced ulcer areas and levels of harmful substances like malondialdehyde.
The highest concentration of WJSS led to the most remarkable reduction in ulcers and improved intestinal bacteria diversity. This suggests that WJSS not only offers promising anti-ulcer effects but also promotes beneficial gut probiotics, pointing towards its potential use in ulcer treatment.
The highest concentration of WJSS led to the most remarkable reduction in ulcers and improved intestinal bacteria diversity. This suggests that WJSS not only offers promising anti-ulcer effects but also promotes beneficial gut probiotics, pointing towards its potential use in ulcer treatment.
Read More
9.5
We explored the potential of a new composite hydrogel that combines probiotics and fucoidan to aid oral ulcer healing. This study focused on how this hydrogel adheres to tissue and releases probiotics effectively. Remarkably, the hydrogels showed better therapeutic results compared to standard oral ulcer patches by promoting faster cell migration and healing.
Overall, this innovative approach suggests a promising future for treating oral ulcers more effectively than traditional methods.
Overall, this innovative approach suggests a promising future for treating oral ulcers more effectively than traditional methods.
Read More
9
We explored the effects of delivering human epidermal growth factor (EGF) through a probiotic strain of E. coli to help treat intestinal ulcers. The study showed that treatment with EGF-EcN not only alleviated ulcers but also helped in restoring damaged barrier layers in the gut. We observed that this method promotes the recovery of important cell types and strengthens mucosal integrity. Importantly, the probiotic did not worsen any cancerous conditions related to ulcerative colitis. Overall, our findings suggest that using probiotics to deliver helpful proteins like EGF can be a safe and effective strategy for managing gastrointestinal ulcers.
Read More
9
We recently explored the protective effects of a specific probiotic called Bifidobacterium breve (Bif195) on small-intestinal damage caused by acetylsalicylic acid (ASA), a common pain reliever. In a randomized, double-blind trial involving 75 healthy volunteers, participants took daily doses of either Bif195 or a placebo for eight weeks.
The results were promising! Those who took Bif195 experienced significantly lower levels of intestinal damage and fewer ulcers compared to the placebo group. Importantly, the use of Bif195 was well tolerated with minimal adverse events reported.
The results were promising! Those who took Bif195 experienced significantly lower levels of intestinal damage and fewer ulcers compared to the placebo group. Importantly, the use of Bif195 was well tolerated with minimal adverse events reported.
Read More
8
Topical probiotics boost ulcer healing
We investigated how probiotics influence healing in traumatic ulcers using an animal model. In our study, we organized rats into control, topical, and systemic probiotic groups to observe differences in healing.
After treatment, we noted that the topical administration of probiotics significantly improved the expression of important healing factors, like TNF-α, and increased the presence of immune cells that aid in recovery.
Our findings suggest that topical probiotics may be more effective than systemic methods for treating traumatic ulcers.
After treatment, we noted that the topical administration of probiotics significantly improved the expression of important healing factors, like TNF-α, and increased the presence of immune cells that aid in recovery.
Our findings suggest that topical probiotics may be more effective than systemic methods for treating traumatic ulcers.
Read More
User Reviews
USERS' SCORE
Good
Based on 3 Reviews
8.8
- All Reviews
- Positive Reviews
- Negative Reviews
10
Life-saving probiotics
I was struggling to eat normal portions due to ulcer symptoms for months. By chance, my brother had probiotics sent to me from abroad. I was losing weight rapidly and thought I might need surgery. Thankfully, after trying a bottle of 30, I was able to eat almost anything within two weeks. I started gaining weight again, and whatever was causing my ulcer symptoms disappeared! I was also experiencing constipation, which was resolved. I'm grateful for my brother's timely delivery. Now, I take them every other day and plan to continue using them as long as possible!
Read More
9
Stomach issues resolved
Renew Life Ultimate Flora Extra Care Probiotic 50 Billion is a fantastic product, and I highly recommend it. As I've aged, I've aimed for a healthier lifestyle and realised I could benefit from probiotics due to past stomach issues, including an ulcer. After a few days of use, I was convinced. I've continued using it daily, and my stomach issues are resolved. Who knew adding positive bacteria to my system could have such a significant impact? I highly recommend this product.
Read More
9.5
Relief from ulcers
In my experience, it's more than a small miracle. I've tried various probiotics over the years, and while this one is costly, it's worth it. For over a decade, I've battled digestive issues, and though other brands helped somewhat, their effectiveness fluctuated. I hesitated to invest in something seemingly similar to what I previously used, but I'm so pleased I did! My immune system often requires antibiotics, which disrupt my digestion and lead to painful mouth ulcers. Since using Renew Life Ultimate Flora Extra Care, I haven't experienced mouth ulcers during antibiotic use, and my digestive issues now emerge later. It's a relief knowing I can recover and enjoy my favourite foods without worry.
Read More
Frequently Asked Questions
No FAQs are available for this product and symptom.
References
- Savitri IJ, Suprarahardiani SA, Ulinnuha LK, Prahasanti C, Wijaksana IKE, et al. TNF-α Expression and Plasma Cell and Macrophage Numbers in Traumatic Ulcers in a Rat Model Treated by Topical or Systemic Probiotic . Int J Med Sci. 2025;22:318. doi:10.7150/ijms.99156
- Cheng Q, Wang K, Lu R, Xiong Y, Luo X, et al. Effect of white jade snail secretion on antioxidant capacity and intestinal microbial diversity in mouse model of acute gastric ulcer. J Sci Food Agric. 2024;104:1723. doi:10.1002/jsfa.13059
- Dou X, Li G, Wang S, Shao D, Wang D, et al. Probiotic-loaded calcium alginate/fucoidan hydrogels for promoting oral ulcer healing. Int J Biol Macromol. 2023;244:125273. doi:10.1016/j.ijbiomac.2023.125273
- Isik M, Ozbayer C, Donmez DB, Colak E, Ustuner MC, et al. Effects of the probiotic, , on ulcer pathogenesis, HSP70 stress protein and nitric oxide levels in stress induced ulcer. Biotech Histochem. 2022;97:449. doi:10.1080/10520295.2022.2028308
- Vijayasarathy S, Gayathri P, Suneetha V. Fermented Foods and Their Abating Role in Gastric Ulcers. J Am Nutr Assoc. 2022;41:826. doi:10.1080/07315724.2021.1962768
- Yu M, Kim J, Ahn JH, Moon Y. Nononcogenic restoration of the intestinal barrier by E. coli-delivered human EGF. JCI Insight. 2019;4. doi:10.1172/jci.insight.125166
- Mortensen B, Murphy C, O'Grady J, Lucey M, Elsafi G, et al. Bifidobacteriumbreve Bif195 Protects Against Small-Intestinal Damage Caused by Acetylsalicylic Acid in Healthy Volunteers. Gastroenterology. 2019;157:637. doi:10.1053/j.gastro.2019.05.008
