Overview

SCIENTIFIC SCORE
Moderately Effective
Based on 16 Researches
8.1
USERS' SCORE
Good
Based on 3 Reviews
8.4
Supplement Facts
Serving Size:  1 Gummy
Amount Per Serving
%DV
Calories
5
 
Total Carbohydrate
2 g 
1%**
Dietary Fiber
<1 g 
2%**
Total Sugars
1 g 
***
Includes 1 g Added Sugars
 
2%**
Sodium
5 mg 
0%
Probiotic Blend1 Billion CFU
10 mg 
***
Bacillus coagulans SNZ 1969,Bacillus subtilis DE111®

Top Medical Research Studies

We explored the effectiveness of BCP92, a probiotic strain, for treating diarrhea in animal models. By using a castor oil-induced diarrhea model in mice, we observed that BCP92 significantly reduced the frequency and onset of diarrhea, leading to less total fecal weight.

The safety of BCP92 was also assessed through acute and sub-acute toxicity studies with rats, showing no harmful side effects at high doses. Overall, our findings suggest that BCP92 is both effective and safe for potential human use in managing diarrhea.
Read More
9
Bacillus coagulans effectively treats diarrhea
We conducted a double-blind, placebo-controlled study involving 60 individuals to assess the effectiveness of Bacillus coagulans LBSC as a treatment for acute diarrhea and related abdominal discomfort. Participants were divided into two groups, one receiving the probiotic and the other a placebo.

Results showed that Bacillus coagulans significantly improved symptoms such as the frequency of unformed stools and abdominal pain resolution. This suggests that the probiotic is not only safe but effective in managing diarrhea and its associated discomfort.
Read More
8
Bacillus coagulans aids piglet health
We investigated Bacillus coagulans as a potential alternative to antibiotics for treating diarrhea in weaned piglets. In a controlled study with 90 piglets over 28 days, we found that those receiving Bacillus coagulans showed improved growth compared to those not receiving it, along with lower diarrhea indices later in the trial. Our analysis also revealed that Bacillus coagulans increased the diversity of gut bacteria, which plays a crucial role in piglet health. Overall, it appears that Bacillus coagulans can positively influence growth and intestinal health in weaned piglets.
Read More

Most Useful Reviews

9
Rapid recovery
3 people found this helpful
It worked brilliantly! My almost three-year-old had diarrhoea for nearly two weeks. At my paediatrician's advice, we used generic probiotics without any improvement. After discovering this product, I read reviews and decided to try it. Remarkably, after just two days, my daughter felt better and stopped having diarrhoea. My four-year-old began experiencing loose stools, and once given these probiotics, she recovered by the following day.
Read More
7.5
Helps diarrhea
2 people found this helpful
My children constantly ask for these! They taste delightful and have just the right sweetness. My son suffers from bad diarrhoea due to antibiotics, but these have greatly assisted him. Just supervise if your one-year-old can handle gummies, as they're not recommended for those under age two due to choking hazards.
Read More
7.5
Constipation relief
1 people found this helpful
These helped my child with constipation. After a stomach bug followed by diarrhoea, my three-year-old was in agony for a week. After starting him on the probiotics, his belly pain vanished, and his stools became softer and more regular. I highly recommend them.
Read More

Medical Researches

SCIENTIFIC SCORE
Moderately Effective
Based on 16 Researches
8.1
  • All Researches
We explored the effectiveness of BCP92, a probiotic strain, for treating diarrhea in animal models. By using a castor oil-induced diarrhea model in mice, we observed that BCP92 significantly reduced the frequency and onset of diarrhea, leading to less total fecal weight.

The safety of BCP92 was also assessed through acute and sub-acute toxicity studies with rats, showing no harmful side effects at high doses. Overall, our findings suggest that BCP92 is both effective and safe for potential human use in managing diarrhea.
Read More
9
Probiotic effective for antibiotic-associated diarrhea
We evaluated the effectiveness of a high-dose, multistrain probiotic mix known as Sinquanon in preventing antibiotic-associated diarrhea (AAD) in adults.

This robust study was a randomized, double-blind, placebo-controlled trial involving 564 participants, where those taking antibiotics received either the probiotic or a placebo.

The findings showed that AAD occurred in just 9.2% of those on the probiotic compared to 25.3% for the placebo group. This indicates that Sinquanon significantly reduces the risk of diarrhea in adults using antibiotics.
Read More
We conducted a clinical trial to examine the effects of LMG S-31876 on diarrhea-predominant irritable bowel syndrome (IBS). In this double-blind, placebo-controlled study, 50 participants received a probiotic supplement, ProBC Plus, or a placebo for 8 weeks.

Encouragingly, we observed a significant reduction in symptoms such as abdominal pain, bloating, and diarrhea in those taking ProBC Plus. This suggests that LMG S-31876 may be beneficial for individuals struggling with IBS-related diarrhea. Throughout the study, participants' health markers remained stable, indicating the treatment's safety.
Read More
9
Bacillus coagulans effectively treats diarrhea
We conducted a double-blind, placebo-controlled study involving 60 individuals to assess the effectiveness of Bacillus coagulans LBSC as a treatment for acute diarrhea and related abdominal discomfort. Participants were divided into two groups, one receiving the probiotic and the other a placebo.

Results showed that Bacillus coagulans significantly improved symptoms such as the frequency of unformed stools and abdominal pain resolution. This suggests that the probiotic is not only safe but effective in managing diarrhea and its associated discomfort.
Read More
We investigated how Bacillus coagulans, specifically Laktovit Forte, can aid in treating diarrhea, especially in cases caused by antibiotics. Using a mouse model simulating intestinal issues and immunodeficiency, we observed notable improvements.

In mice suffering from colitis triggered by streptomycin, B. coagulans significantly reduced diarrhea, restored gastrointestinal function, and prevented weight loss. Additionally, it showed a superior effectiveness in boosting immunity compared to another probiotic product.

Overall, our results highlight the promising role of B. coagulans in managing diarrhea linked to antibiotics.
Read More

User Reviews

USERS' SCORE
Good
Based on 3 Reviews
8.4
  • All Reviews
  • Positive Reviews
  • Negative Reviews
9
Rapid recovery
3 people found this helpful
It worked brilliantly! My almost three-year-old had diarrhoea for nearly two weeks. At my paediatrician's advice, we used generic probiotics without any improvement. After discovering this product, I read reviews and decided to try it. Remarkably, after just two days, my daughter felt better and stopped having diarrhoea. My four-year-old began experiencing loose stools, and once given these probiotics, she recovered by the following day.
Read More
7.5
Helps diarrhea
2 people found this helpful
My children constantly ask for these! They taste delightful and have just the right sweetness. My son suffers from bad diarrhoea due to antibiotics, but these have greatly assisted him. Just supervise if your one-year-old can handle gummies, as they're not recommended for those under age two due to choking hazards.
Read More
7.5
Constipation relief
1 people found this helpful
These helped my child with constipation. After a stomach bug followed by diarrhoea, my three-year-old was in agony for a week. After starting him on the probiotics, his belly pain vanished, and his stools became softer and more regular. I highly recommend them.
Read More

Frequently Asked Questions

9
Bacillus coagulans effectively treats diarrhea
We conducted a double-blind, placebo-controlled study involving 60 individuals to assess the effectiveness of Bacillus coagulans LBSC as a treatment for acute diarrhea and related abdominal discomfort. Participants were divided into two groups, one receiving the probiotic and the other a placebo.

Results showed that Bacillus coagulans significantly improved symptoms such as the frequency of unformed stools and abdominal pain resolution. This suggests that the probiotic is not only safe but effective in managing diarrhea and its associated discomfort.
We explored the effectiveness of BCP92, a probiotic strain, for treating diarrhea in animal models. By using a castor oil-induced diarrhea model in mice, we observed that BCP92 significantly reduced the frequency and onset of diarrhea, leading to less total fecal weight.

The safety of BCP92 was also assessed through acute and sub-acute toxicity studies with rats, showing no harmful side effects at high doses. Overall, our findings suggest that BCP92 is both effective and safe for potential human use in managing diarrhea.
9
Probiotic effective for antibiotic-associated diarrhea
We evaluated the effectiveness of a high-dose, multistrain probiotic mix known as Sinquanon in preventing antibiotic-associated diarrhea (AAD) in adults.

This robust study was a randomized, double-blind, placebo-controlled trial involving 564 participants, where those taking antibiotics received either the probiotic or a placebo.

The findings showed that AAD occurred in just 9.2% of those on the probiotic compared to 25.3% for the placebo group. This indicates that Sinquanon significantly reduces the risk of diarrhea in adults using antibiotics.
We explored the impact of the probiotic MTCC 5856 as an addition to standard treatments for children's acute diarrhea. In a carefully controlled study with 110 children, we found that those receiving MTCC 5856, along with oral rehydration solutions and zinc, experienced a reduced duration of diarrhea compared to those getting a placebo.

While the frequency of diarrhea improved, it wasn’t statistically significant. Importantly, all children remained safe throughout the study, showcasing the potential of probiotics as a helpful option in managing diarrhea in young patients.

References

  1. Wang J, Zhang Z, Wang J, Shi L, Wang S, et al. Bacillus coagulans alleviates intestinal barrier injury induced by Klebsiella pneumoniae in rabbits by regulating the TLR4/MyD88/NF-κB signalling pathway. Vet Microbiol. 2025;301:110364. 10.1016/j.vetmic.2024.110364
  2. Shaikh SS, Patel S, Malik A, Kumar S A. Efficacy and safety assessment of probiotic BCP92 for treatment of diarrhea. Toxicol Res (Camb). 2024;13:tfae182. 10.1093/toxres/tfae182
  3. Hodzhev V, Dzhambazov K, Sapundziev N, Encheva M, Todorov S, et al. High-dose Probiotic Mix of spp., spp., , and to Prevent Antibiotic-associated Diarrhea in Adults: A Multicenter, Randomized, Double-blind, Placebo-controlled Trial (SPAADA). Open Forum Infect Dis. 2024;11:ofae615. 10.1093/ofid/ofae615
  4. Kallur RK, Madapati S, Mathur A, Bhattacharya S. The role of LMG S-31876 in treating IBS-diarrhea. Front Nutr. 2023;10:1310462. 10.3389/fnut.2023.1310462
  5. Majeed M, Nagabhushanam K, Arumugam S, Chadalavada N, Seepana J, et al. Probiotic MTCC 5856 as adjunct therapy in children's acute diarrhea-a randomized, double-blind, placebo-controlled study. Front Pediatr. 2023;11:1338126. 10.3389/fped.2023.1338126
  6. Teichenné J, Catalán Ú, Mariné-Casadó R, Domenech-Coca C, Mas-Capdevila A, et al. Bacillus coagulans GBI-30, 6086 (BC30) improves lactose digestion in rats exposed to a high-lactose meal. Eur J Nutr. 2023;62:2649. 10.1007/s00394-023-03183-z
  7. A AJ, Suresh A. Oral microbial shift induced by probiotic Bacillus coagualans along with its clinical perspectives. J Oral Biol Craniofac Res. 2023;13:398. 10.1016/j.jobcr.2023.03.013
  8. Chaudhari K, Mohan M, Saudagar P, Sable C, Shinde S, et al. In vitro and in vivo evaluation of probiotic potential and safety assessment of Bacillus coagulans SKB LAB-19 (MCC 0554) in humans and animal healthcare. Regul Toxicol Pharmacol. 2022;133:105218. 10.1016/j.yrtph.2022.105218
  9. Sun T, Miao H, Zhang C, Wang Y, Liu S, et al. Effect of dietary Bacillus coagulans on the performance and intestinal microbiota of weaned piglets. Animal. 2022;16:100561. 10.1016/j.animal.2022.100561
  10. Gupta AK, Maity C. Efficacy and safety of Bacillus coagulans LBSC in irritable bowel syndrome: A prospective, interventional, randomized, double-blind, placebo-controlled clinical study [CONSORT Compliant]. Medicine (Baltimore). 2021;100:e23641. 10.1097/MD.0000000000023641
  11. Maity C, Gupta AK. A prospective, interventional, randomized, double-blind, placebo-controlled clinical study to evaluate the efficacy and safety of Bacillus coagulans LBSC in the treatment of acute diarrhea with abdominal discomfort. Eur J Clin Pharmacol. 2019;75:21. 10.1007/s00228-018-2562-x
  12. Pu J, Chen D, Tian G, He J, Zheng P, et al. Protective Effects of Benzoic Acid, Coagulans, and Oregano Oil on Intestinal Injury Caused by Enterotoxigenic in Weaned Piglets. Biomed Res Int. 2018;2018:1829632. 10.1155/2018/1829632
  13. Wu T, Zhang Y, Lv Y, Li P, Yi D, et al. Beneficial Impact and Molecular Mechanism of on Piglets' Intestine. Int J Mol Sci. 2018;19. 10.3390/ijms19072084
  14. Bomko TV, Nosalskaya TN, Kabluchko TV, Lisnyak YV, Martynov AV. Immunotropic aspect of the Bacillus coagulans probiotic action. J Pharm Pharmacol. 2017;69:1033. 10.1111/jphp.12726
  15. Majeed M, Nagabhushanam K, Natarajan S, Sivakumar A, Ali F, et al. Bacillus coagulans MTCC 5856 supplementation in the management of diarrhea predominant Irritable Bowel Syndrome: a double blind randomized placebo controlled pilot clinical study. Nutr J. 2016;15:21. 10.1186/s12937-016-0140-6
  16. Rogha M, Esfahani MZ, Zargarzadeh AH. The efficacy of a synbiotic containing Bacillus Coagulans in treatment of irritable bowel syndrome: a randomized placebo-controlled trial. Gastroenterol Hepatol Bed Bench. 2014;7:156.
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