We explored the effectiveness of BCP92, a probiotic strain, for treating diarrhea in animal models. By using a castor oil-induced diarrhea model in mice, we observed that BCP92 significantly reduced the frequency and onset of diarrhea, leading to less total fecal weight.
The safety of BCP92 was also assessed through acute and sub-acute toxicity studies with rats, showing no harmful side effects at high doses. Overall, our findings suggest that BCP92 is both effective and safe for potential human use in managing diarrhea.
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We evaluated the effectiveness of a high-dose, multistrain probiotic mix known as Sinquanon in preventing antibiotic-associated diarrhea (AAD) in adults.
This robust study was a randomized, double-blind, placebo-controlled trial involving 564 participants, where those taking antibiotics received either the probiotic or a placebo.
The findings showed that AAD occurred in just 9.2% of those on the probiotic compared to 25.3% for the placebo group. This indicates that Sinquanon significantly reduces the risk of diarrhea in adults using antibiotics.
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We conducted a clinical trial to examine the effects of LMG S-31876 on diarrhea-predominant irritable bowel syndrome (IBS). In this double-blind, placebo-controlled study, 50 participants received a probiotic supplement, ProBC Plus, or a placebo for 8 weeks.
Encouragingly, we observed a significant reduction in symptoms such as abdominal pain, bloating, and diarrhea in those taking ProBC Plus. This suggests that LMG S-31876 may be beneficial for individuals struggling with IBS-related diarrhea. Throughout the study, participants' health markers remained stable, indicating the treatment's safety.
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Bacillus coagulans effectively treats diarrheaA prospective, interventional, randomized, double-blind, placebo-controlled clinical study to evaluate the efficacy and safety of Bacillus coagulans LBSC in the treatment of acute diarrhea with abdominal discomfort.
Probiotic treatment relevance established.
We conducted a double-blind, placebo-controlled study involving 60 individuals to assess the effectiveness of Bacillus coagulans LBSC as a treatment for acute diarrhea and related abdominal discomfort. Participants were divided into two groups, one receiving the probiotic and the other a placebo.
Results showed that Bacillus coagulans significantly improved symptoms such as the frequency of unformed stools and abdominal pain resolution. This suggests that the probiotic is not only safe but effective in managing diarrhea and its associated discomfort.
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We investigated how Bacillus coagulans, specifically Laktovit Forte, can aid in treating diarrhea, especially in cases caused by antibiotics. Using a mouse model simulating intestinal issues and immunodeficiency, we observed notable improvements.
In mice suffering from colitis triggered by streptomycin, B. coagulans significantly reduced diarrhea, restored gastrointestinal function, and prevented weight loss. Additionally, it showed a superior effectiveness in boosting immunity compared to another probiotic product.
Overall, our results highlight the promising role of B. coagulans in managing diarrhea linked to antibiotics.
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