Overview

SCIENTIFIC SCORE
Moderately Effective
Based on 43 Researches
8
USERS' SCORE
Good
Based on 2 Reviews
8.3
Supplement Facts
Serving Size:  1 Capsule
Amount Per Serving
%DV
Women's Care Probiotic Blend
50 Billion CFU 222 mg
***
Bifido Probiotic BlendBifidobacterium lactis BI-04®, Bifidobacterium lactis DSM 15954, Bifidobacterium infantis Bi-26™
26 Billion CFU
 
Lacto Probiotic BlendLactobacillus reuteri RC-14®, Lactobacillus plantarum Lp-115®, Lactobacillus rhamnosus GG, Lactobacillus rhamnosus GR-1®, Lactococcus lactis LI-23™, Lactobacillus casei Lc-11®, Lactobacillus paracasei Lpc-37®, Lactobacillus acidophilus La-14®, Lactobacillus brevis Lbr-35™
24 Billion CFU
 

Top Medical Research Studies

9
Probiotic improves allergic asthma
We explored how the probiotic strain CCFM1274 affects allergic asthma symptoms by modifying tryptophan metabolism. Using a mouse model, we administered ovalbumin to induce asthma and treated the mice with CCFM1274. The results were promising; this probiotic reduced both weight loss and mortality in the mice.

We also noticed a drop in specific immunoglobulin E levels and inflammatory cytokines, indicating improved lung health. CCFM1274 appears to help remodel gut metabolism, leading to better management of allergic asthma symptoms as demonstrated in our study.
Read More
9
Probiotics beneficial for allergies
Our study asked whether a specific mixture of probiotics could help alleviate allergic rhinitis symptoms in children. We enrolled 250 kids, half receiving the probiotic mixture alongside their regular allergy treatment, and the other half getting a placebo.

The results were promising! Those in the probiotic group experienced a significant reduction in allergy symptoms and less reliance on allergy medications. This evidence suggests that probiotics might be a helpful addition to managing allergic rhinitis in children.
Read More
9
Food allergy symptom reduction observed
We investigated how bifidobacterium lactis could help with food allergies in children by observing changes in specific immune cells. In our study, 256 children with food allergies were split into two groups: one received the treatment and the other a placebo, both for three months.

We noted a significant reduction in allergic symptoms and related markers in the treatment group compared to the placebo group. Additionally, results in a mouse model mirrored these findings, showing improved immune responses linked to beneficial cells. Overall, bifidobacterium lactis appears promising for managing food allergies.
Read More

Most Useful Reviews

7.5
Relief from infections
7 people found this helpful
Good probiotic blend. I am only 30 days into my first bottle, but so far, so good. I had issues with yeast due to medications I take for asthma and allergies. After three months of chronic infections and trying two other probiotics that didn't work, I am feeling much better. I'll be ordering another bottle shortly and expect to continue experiencing relief.
Read More
7.5
Balanced my yeast
6 people found this helpful
Good for people with dairy allergies. I have dairy allergies, so this has been great for my issue. I didn't realise I could be allergic to probiotics, but I've experienced rashes after taking other brands. I definitely see it has helped balance my yeast. I recommend this and am now on my second bottle as not all probiotics are the same.
Read More

Medical Researches

SCIENTIFIC SCORE
Moderately Effective
Based on 43 Researches
8
  • All Researches
We sought to understand if Bifiform Kids, a probiotic, could help prevent respiratory infections in children with recurrent infections and gastrointestinal allergy symptoms. In our controlled trial with 92 children aged 4 to 5, those taking the probiotic showed a significant 3-fold reduction in respiratory infections compared to the control group.

After 21 days, there were notable immune system improvements, including an increase in protective IgA levels and a decrease in allergic IgE. These findings suggest that Bifiform Kids is effective for preventing respiratory infections in children facing allergic issues.
Read More
9
Probiotic improves allergic asthma
We explored how the probiotic strain CCFM1274 affects allergic asthma symptoms by modifying tryptophan metabolism. Using a mouse model, we administered ovalbumin to induce asthma and treated the mice with CCFM1274. The results were promising; this probiotic reduced both weight loss and mortality in the mice.

We also noticed a drop in specific immunoglobulin E levels and inflammatory cytokines, indicating improved lung health. CCFM1274 appears to help remodel gut metabolism, leading to better management of allergic asthma symptoms as demonstrated in our study.
Read More
9
Probiotic reduces food allergy symptoms
This prospective randomized controlled study involved 92 children aged 4 to 5 with food allergies affecting their skin and gastrointestinal system.

Half of the children received a combined probiotic over 21 days, resulting in reduced allergy symptoms and lower IgE levels compared to the control group.

After treatment, significant improvements in skin conditions and gastrointestinal issues were noted, showcasing the probiotic's potential to alleviate allergy symptoms and rebalance specific immune responses.
Read More
9
Probiotics beneficial for allergies
Our study asked whether a specific mixture of probiotics could help alleviate allergic rhinitis symptoms in children. We enrolled 250 kids, half receiving the probiotic mixture alongside their regular allergy treatment, and the other half getting a placebo.

The results were promising! Those in the probiotic group experienced a significant reduction in allergy symptoms and less reliance on allergy medications. This evidence suggests that probiotics might be a helpful addition to managing allergic rhinitis in children.
Read More
9
We investigated how a daily symbiotic food supplement could affect birch pollen allergies in patients with rhinoconjunctivitis. This study used an allergen exposure chamber, allowing us to standardize pollen exposure and track symptoms effectively.

Over four months, the supplement seemed to enhance patients' overall well-being and significantly improve allergy symptoms during controlled exposures. The findings suggest a promising role for such supplements in managing allergic rhinitis, with a strong safety record.
Read More

User Reviews

USERS' SCORE
Good
Based on 2 Reviews
8.3
  • All Reviews
  • Positive Reviews
  • Negative Reviews
7.5
Relief from infections
7 people found this helpful
Good probiotic blend. I am only 30 days into my first bottle, but so far, so good. I had issues with yeast due to medications I take for asthma and allergies. After three months of chronic infections and trying two other probiotics that didn't work, I am feeling much better. I'll be ordering another bottle shortly and expect to continue experiencing relief.
Read More
7.5
Balanced my yeast
6 people found this helpful
Good for people with dairy allergies. I have dairy allergies, so this has been great for my issue. I didn't realise I could be allergic to probiotics, but I've experienced rashes after taking other brands. I definitely see it has helped balance my yeast. I recommend this and am now on my second bottle as not all probiotics are the same.
Read More

Frequently Asked Questions

No FAQs are available for this product and symptom.

References

  1. Wang H, He Y, Dang D, Feng L, Huang L, et al. subsp. CCFM1274 relieved allergic asthma symptoms by modifying intestinal tryptophan metabolism in mice. Food Funct. 2024;15:8810. 10.1039/d4fo01079e
  2. Adjibade M, Vigneron L, Delvert R, Adel-Patient K, Divaret-Chauveau A, et al. Characteristics of infant formula consumed in the first months of life and allergy in the EDEN mother-child cohort. Matern Child Nutr. 2024;20:e13673. 10.1111/mcn.13673
  3. Li L, Wen X, Gong Y, Chen Y, Xu J, et al. HMGN2 and Histone H1.2: potential targets of a novel probiotic mixture for seasonal allergic rhinitis. Front Microbiol. 2023;14:1202858. 10.3389/fmicb.2023.1202858
  4. Komulainen M, Saros L, Vahlberg T, Nermes M, Jartti T, et al. Maternal fish oil and/or probiotics intervention: Allergic diseases in children up to two years old. Pediatr Allergy Immunol. 2023;34:e14004. 10.1111/pai.14004
  5. Vorobieva OA, Shih EV, Drozdov VN, Shikh NV. [The results of the use of a combined probiotic ( and spp. Ð’B-12) in children with gastrointestinal and skin manifestations of food allergy]. Vopr Pitan. 2023;92:79. 10.33029/0042-8833-2023-92-3-79-86
  6. Tian X, Liang X, He H, Cui Q, Liu Q, et al. Probiotics Alleviate Food Protein Allergy in Mice by Activating TLR4 Signaling Pathway. Mol Nutr Food Res. 2023;67:e2200579. 10.1002/mnfr.202200579
  7. Bezruk VV, Godovanets OS, Buriak OH, Voytkevich NI, Makarova OV, et al. The use of hydrolyzed formulas as a method of correction of feeding and clinical rehabilitation of infants with atopy signs. J Med Life. 2022;15:1536. 10.25122/jml-2022-0254
  8. Feíto-Rodríguez M, Ramírez-Boscà A, Vidal-Asensi S, Fernández-Nieto D, Ros-Cervera G, et al. Randomized double-blind placebo-controlled clinical trial to evaluate the effect of a mixture of probiotic strains on symptom severity and use of corticosteroids in children and adolescents with atopic dermatitis. Clin Exp Dermatol. 2023;48:495. 10.1093/ced/llad007
  9. Shikh EV, Drozdov VN, Vorobieva OA, Zhukova OV, Ermolaeva AS, et al. [The effectiveness of BIFIFORM KIDS in the prevention of the incidence of acute respiratory infections in children]. Vopr Pitan. 2022;91:97. 10.33029/0042-8833-2022-91-4-97-106
  10. Uwaezuoke SN, Ayuk AC, Eze JN, Odimegwu CL, Ndiokwelu CO, et al. Postnatal probiotic supplementation can prevent and optimize treatment of childhood asthma and atopic disorders: A systematic review of randomized controlled trials. Front Pediatr. 2022;10:956141. 10.3389/fped.2022.956141
  11. Anania C, Di Marino VP, Olivero F, De Canditiis D, Brindisi G, et al. Treatment with a Probiotic Mixture Containing Subsp. BB12 and L3 for the Prevention of Allergic Rhinitis Symptoms in Children: A Randomized Controlled Trial. Nutrients. 2021;13. 10.3390/nu13041315
  12. Tan-Lim CSC, Esteban-Ipac NAR, Recto MST, Castor MAR, Casis-Hao RJ, et al. Comparative effectiveness of probiotic strains on the prevention of pediatric atopic dermatitis: A systematic review and network meta-analysis. Pediatr Allergy Immunol. 2021;32:1255. 10.1111/pai.13514
  13. Bergmann KC, Krause L, Hiller J, Becker S, Kugler S, et al. First evaluation of a symbiotic food supplement in an allergen exposure chamber in birch pollen allergic patients. World Allergy Organ J. 2021;14:100494. 10.1016/j.waojou.2020.100494
  14. Tan-Lim CSC, Esteban-Ipac NAR, Mantaring JBV, Chan Shih Yen E, Recto MST, et al. Comparative effectiveness of probiotic strains for the treatment of pediatric atopic dermatitis: A systematic review and network meta-analysis. Pediatr Allergy Immunol. 2021;32:124. 10.1111/pai.13305
  15. Schmidt RM, Pilmann Laursen R, Bruun S, Larnkjaer A, Mølgaard C, et al. Probiotics in late infancy reduce the incidence of eczema: A randomized controlled trial. Pediatr Allergy Immunol. 2019;30:335. 10.1111/pai.13018
  16. Liu Q, Jing W, Wang W. Ameliorates the Risk of Food Allergy in Chinese Children by Affecting Relative Percentage of Treg and Th17 Cells. Can J Infect Dis Med Microbiol. 2018;2018:4561038. 10.1155/2018/4561038
  17. Kim WK, Jang YJ, Park S, Min SG, Kwon H, et al. Lactobacillus acidophilus KBL409 Ameliorates Atopic Dermatitis in a Mouse Model. J Microbiol. 2024;62:91. 10.1007/s12275-024-00104-5
  18. Husein-ElAhmed H, Steinhoff M. Effects of probiotic supplementation in adult with atopic dermatitis: a systematic review with meta-analysis. Clin Exp Dermatol. 2023;49:46. 10.1093/ced/llad318
  19. Li A, Yang J, Zhang C, Chi H, Zhang C, et al. Lactobacillus acidophilus KLDS 1.0738 inhibits TLR4/NF-κB inflammatory pathway in β-lactoglobulin-induced macrophages via modulating miR-146a. J Food Biochem. 2021;45:e13662. 10.1111/jfbc.13662
  20. Ni WW, Zhang QM, Zhang X, Li Y, Yu SS, et al. Modulation effect of Lactobacillus acidophilus KLDS 1.0738 on gut microbiota and TLR4 expression in β-lactoglobulin-induced allergic mice model. Allergol Immunopathol (Madr). 2020;48:149. 10.1016/j.aller.2019.06.002
  21. Wang JJ, Zhang QM, Ni WW, Zhang X, Li Y, et al. Modulatory effect of Lactobacillus acidophilus KLDS 1.0738 on intestinal short-chain fatty acids metabolism and GPR41/43 expression in β-lactoglobulin-sensitized mice. Microbiol Immunol. 2019;63:303. 10.1111/1348-0421.12723
  22. Nakata J, Hirota T, Umemura H, Nakagawa T, Kando N, et al. Additive effect of L-92 on children with atopic dermatitis concomitant with food allergy. Asia Pac Allergy. 2019;9:e18. 10.5415/apallergy.2019.9.e18
  23. Wang JJ, Li SH, Li AL, Zhang QM, Ni WW, et al. Effect of Lactobacillus acidophilus KLDS 1.0738 on miRNA expression in in vitro and in vivo models of β-lactoglobulin allergy. Biosci Biotechnol Biochem. 2018;82:1955. 10.1080/09168451.2018.1495551
  24. Li AL, Sun YQ, Du P, Meng XC, Guo L, et al. The Effect of Lactobacillus actobacillus Peptidoglycan on Bovine β-Lactoglobulin-Sensitized Mice via TLR2/NF-κB Pathway. Iran J Allergy Asthma Immunol. 2017;16:147.
  25. Rø ADB, Simpson MR, Rø TB, Storrø O, Johnsen R, et al. Reduced Th22 cell proportion and prevention of atopic dermatitis in infants following maternal probiotic supplementation. Clin Exp Allergy. 2017;47:1014. 10.1111/cea.12930
  26. Gelardi M, De Luca C, Taliente S, Fiorella ML, Quaranta N, et al. Adjuvant treatment with a symbiotic in patients with inflammatory non-allergic rhinitis. J Biol Regul Homeost Agents. 2017;31:201.
  27. Shen X, Li M, Shi L, Ling N, He M, et al. [The Immunomodulatory and Anti-allergy Effects of Lactobacilli]. Sichuan Da Xue Xue Bao Yi Xue Ban. 2016;47:192.
  28. Yamamoto K, Yokoyama K, Matsukawa T, Kato S, Kato S, et al. Efficacy of prolonged ingestion of Lactobacillus acidophilus L-92 in adult patients with atopic dermatitis. J Dairy Sci. 2016;99:5039. 10.3168/jds.2015-10605
  29. Shandilya UK, Sharma A, Kapila R, Kansal VK. Probiotic Dahi containing Lactobacillus acidophilus and Bifidobacterium bifidum modulates immunoglobulin levels and cytokines expression in whey proteins sensitised mice. J Sci Food Agric. 2016;96:3180. 10.1002/jsfa.7497
  30. Simpson MR, Dotterud CK, Storrø O, Johnsen R, Øien T. Perinatal probiotic supplementation in the prevention of allergy related disease: 6 year follow up of a randomised controlled trial. BMC Dermatol. 2015;15:13. 10.1186/s12895-015-0030-1
  31. Xu H, Duan X, Wang Y, Geng W. Amelioration Effect of ZW3 on Ovalbumin-Induced Allergic Symptoms in BALB/c Mice. Foods. 2024;14. 10.3390/foods14010016
  32. Lungaro L, Malfa P, Manza F, Costanzini A, Valentini G, et al. Clinical Efficacy of Probiotics for Allergic Rhinitis: Results of an Exploratory Randomized Controlled Trial. Nutrients. 2024;16. 10.3390/nu16234173
  33. Song S, Zhang H, Liu L, Li M, Wang X, et al. Probiotic DNA regulates intestinal Th2 polarization by inducing epithelial cells to produce PD-L1. Apoptosis. 2025;30:239. 10.1007/s10495-024-02043-3
  34. Mennini M, Piccirillo M, Furio S, Valitutti F, Ferretti A, et al. Probiotics and other adjuvants in allergen-specific immunotherapy for food allergy: a comprehensive review. Front Allergy. 2024;5:1473352. 10.3389/falgy.2024.1473352
  35. Malekiantaghi A, Ghanaati F, Shabani-Mirzaee H, Shariat M, Mojtahedi SY, et al. Helps to Reduce the Duration of Bleeding in Breastfed Infants with Allergic Proctocolitis. Breastfeed Med. 2025;20:59. 10.1089/bfm.2024.0185
  36. Xue J, Liu Z, Xie B, Dong R, Wu J, et al. Probiotic nucleotides increase IL-10 expression in airway macrophages to mitigate airway allergy. Inflamm Res. 2024;73:1919. 10.1007/s00011-024-01940-2
  37. Puisto R, Gómez-Gallego C, Collado MC, Turta O, Isolauri E, et al. The Role of Infant Gut Microbiota Modulation by Perinatal Maternal Probiotic Intervention in Atopic Eczema Risk Reduction. Neonatology. 2025;122:84. 10.1159/000540075
  38. Uberos J, Garcia-Cuesta A, Carrasco-Solis M, Ruiz-López A, Fernandez-Marı N E, et al. Lacticaseibacillus rhamnosus and breastmilk are associated with a decreased risk of atopic dermatitis in very low birth weight premature infants. Benef Microbes. 2023;14:433. 10.1163/18762891-20220144
  39. Shi J, Dong P, Liu C, Xu Y, Zheng M, et al. Probio-M9 alleviates OVA-sensitized food allergy through modulating gut microbiota and its metabolism. Food Funct. 2023;14:10784. 10.1039/d3fo03321j
  40. Vasconcelos JA, Mota AS, Olímpio F, Rosa PC, Damaceno-Rodrigues N, et al. Lactobacillus rhamnosus Modulates Lung Inflammation and Mitigates Gut Dysbiosis in a Murine Model of Asthma-COPD Overlap Syndrome. Probiotics Antimicrob Proteins. 2025;17:588. 10.1007/s12602-023-10167-2
  41. Tan Lim CSC, Sajo MEJV, Orteza KEMP, Fernandez PBA, Vila MJC. Next-Gen biotherapeutics: A systematic review and network meta-analysis on postbiotics as treatment for pediatric atopic dermatitis. Pediatr Allergy Immunol. 2023;34:e14022. 10.1111/pai.14022
  42. Hou Y, Zheng S, Zou F, Wang D, Da H, et al. Lactobacillus rhamnosus 76 alleviates airway inflammation in ovalbumin-allergic mice and improves mucus secretion by down-regulating STAT6/SPDEF pathway. Immunobiology. 2023;228:152712. 10.1016/j.imbio.2023.152712
  43. Lee JY, Park JY, Jeong Y, Kang CH. Anti-Inflammatory Response in TNFα/IFNγ-Induced HaCaT Keratinocytes and Probiotic Properties of MG4644, MG4693, and MG5474. J Microbiol Biotechnol. 2023;33:1039. 10.4014/jmb.2301.01028
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