Medical Researches
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Based on 4 Researches
Zinc therapy shows promise for coughA Potential Novel Treatment for Chronic Cough in Long COVID Patients: Clearance of Epipharyngeal Residual SARS-CoV-2 Spike RNA by Epipharyngeal Abrasive Therapy.
Zinc effects noted among treatments
We explored the effectiveness of Epipharyngeal Abrasive Therapy (EAT) in addressing chronic cough, particularly in the context of Long COVID. This treatment, prevalent in Japan, uses zinc chloride to reduce inflammation in the epipharyngeal mucosa. We followed a 21-year-old man whose chronic cough persisted for four months after a mild COVID-19 infection. Upon diagnosis, we identified chronic epipharyngitis as the culprit behind his ongoing cough.
The EAT involved weekly treatments for three months. We observed that this therapy not only cleared residual SARS-CoV-2 spike RNA from the epipharyngeal mucosa but also led to a decrease in inflammation and proinflammatory cytokines. While the application of zinc chloride was a significant part of the treatment, it was combined with other elements of EAT, making it challenging to isolate zinc's specific impact on cough relief.
Overall, we found that EAT could be a promising avenue for individuals suffering from chronic cough related to Long COVID, highlighting an innovative way to utilize zinc in managing this persistent symptom.
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Zinc in mixed COVID treatmentEfficacy and Safety of Aspirin, Promethazine, and Micronutrients for Rapid Clinical Recovery in Mild to Moderate COVID-19 Patients: A Randomized Controlled Clinical Trial.
Partial impact of zinc noted
We conducted a rigorous randomized controlled trial to evaluate the effectiveness of an innovative treatment involving a combination of two tablets: one with Aspirin and Promethazine, and another packed with essential micronutrients like vitamin D3, C, B3, zinc, and selenium. Our aim was to determine how this combination affects the symptoms of mild to moderate COVID-19, particularly cough.
Our study included 260 patients and followed a strict methodology, comparing this new treatment to the standard clinical management recommended by the Indian Council of Medical Research. Over a treatment period of 10 days, we observed notable improvements in symptoms, including cough, myalgia, headache, and anosmia, among those who received the APMV2020 treatment alongside standard care.
While zinc was included in the treatment, this study does not isolate its effect on cough specifically since it was part of a comprehensive combination. However, our findings indicated that APMV2020 treatment led to a significant reduction in cough symptoms and inflammatory markers. This positions APMV2020 as a promising candidate for inclusion in COVID-19 management protocols, not only for rapid recovery but also for its potential long-term benefits in reducing complications associated with the virus.
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Elderberry aids COPD symptomsClinical Effectiveness of a Combination of Black Elder Berries, Violet Herb, and Calendula Flowers in Chronic Obstructive Pulmonary Disease: The Results of a Double-Blinded Placebo-Controlled Study.
Effectiveness of elderberry unclear
In our recent study, we investigated the potential benefits of a natural preparation called Inflaminat, which includes black elderberry, violet herb, and calendula flowers, on cough and other symptoms of chronic obstructive pulmonary disease (COPD). Conducted over six months, this randomized double-blind placebo-controlled trial involved 60 patients with moderate COPD.
We observed that those taking Inflaminat experienced a significant improvement in their symptoms as measured by the Breathlessness, Cough, and Sputum Scale. Specifically, their scores decreased from an average of 3.0 to 1.9, indicating less breathlessness and fewer cough symptoms. Additionally, their lung function improved, with a marked increase in the FEV1 measurement from 66% to 73%.
Importantly, participants in the placebo group showed no similar improvements, reinforcing the effectiveness of the natural remedy. Furthermore, we found no side effects associated with the preparation. Our findings suggest that herbal remedies, particularly those containing elderberry, could be valuable in alleviating cough and improving respiratory function in patients suffering from COPD.
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Zinc acetate ineffective for coughEfficacy and tolerability of zinc acetate for treatment of chronic refractory cough: pilot randomised futility trial.
Directly investigates zinc's effect
We conducted a pilot trial to explore the effectiveness of zinc acetate in treating chronic refractory cough, a condition that causes significant discomfort for many people. In this study, we compared zinc acetate against a placebo over a period of six weeks, with the aim of measuring improvements in quality of life and cough symptoms using several established questionnaires.
Our group included 34 participants who were primarily white females suffering from moderate to severe cough. Throughout the trial, we noted that those taking zinc acetate did experience a rise in serum zinc levels, which indicates that the treatment was effective in that regard. However, when assessing the overall impact on cough symptoms and quality of life, both the zinc and placebo groups showed improvements, but those improvements were minimal.
Importantly, the treatment effects observed did not reach the clinically meaningful thresholds that would suggest zinc acetate significantly benefits cough management. Therefore, we concluded that there is no substantial advantage to using zinc therapy over placebo for people dealing with chronic cough, and suggest that larger trials are unnecessary at this time.
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User Reviews
NUMBER ONE FOR SORE THROAT AND COUGH. This Sambucol Black Elderberry syrup tastes amazing and is healthy. It works better than what I used to get from my doctor for sore throats and coughs. I also appreciate that it boosts the immune system with high antioxidant levels. I recommend this product, and many would agree that doctors have never prescribed anything that tastes good. I bought the 7.8 oz bottle to ensure I have enough for a long time.
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I'm a believer in elderberry as a cough syrup! I experienced a severe cough in November 2019, and elderberry syrup was the one thing that subdued the cough and cleared my congestion. I even recommend it to my children and grandchildren. It's been a reliable remedy for us all!
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Elderberry Rocks! As a grandmother who cares for my grandbabies, I often avoid illness with elderberry. I started with a daily 10ml dose two days before visiting. If I feel a sore throat, I increase my dosage to four times a day. Thanks to my elderberry routine, I’ve avoided full-blown colds during my visits, while others caught illnesses after the same exposure. I think taking multiple elderberry supplements consistently is key, and I rely on Sambucol to keep me healthy.
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Remarkable immunity boost
An Ancient Remedy. I decided to improve my immunity after experiencing frequent illnesses with my brother's kids. From tribal teachings, I understand the benefits of elderberries. Having purchased Sambucol, I was thrilled with the outcome—after taking it four times daily during a bad cold spell in my family, I remained healthy. I now take it daily, ensuring I avoid any signs of illness, and it helps the children with their coughs and runny noses.
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Works for us! I was told about a study showing that Sambucol helps fight colds and viruses. After previously enduring numerous doctors' visits due to my children's persistent colds, I started giving them Sambucol at the first sign of illness. Now, after an entire winter without sick visits, it’s clear that this remedy, paired with honey and healthy foods, has made a significant difference.
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