5/5/2025
Last update
5/5/2025
Reviewed By
Overview
SCIENTIFIC SCORE
Questionable
Based on 4 Researches
6.5
USERS' SCORE
Good
Based on 85 Reviews
8.7
Supplement Facts
Serving Size: 2 Teaspoons (10 ml)
Serving Per Container: 12
Amount Per Serving
%DV
Calories
25
Total Carbohydrate
7 g
3%†
Total Sugars
7 g
**
Includes 3.1 g Added Sugars
6.2%
Vitamin C (ascorbic acid)
110 mg
122%
Zinc (as zinc gluconate)
2.6 mg
24%
Black Elderberry Extract
3.8 g
**
Top Medical Research Studies
2
We conducted a pilot trial to explore the effectiveness of zinc acetate in treating chronic refractory cough, a condition that causes significant discomfort for many people. In this study, we compared zinc acetate against a placebo over a period of six weeks, with the aim of measuring improvements in quality of life and cough symptoms using several established questionnaires.
Our group included 34 participants who were primarily white females suffering from moderate to severe cough. Throughout the trial, we noted that those taking zinc acetate did experience a rise in serum zinc levels, which indicates that the treatment was effective in that regard. However, when assessing the overall impact on cough symptoms and quality of life, both the zinc and placebo groups showed improvements, but those improvements were minimal.
Importantly, the treatment effects observed did not reach the clinically meaningful thresholds that would suggest zinc acetate significantly benefits cough management. Therefore, we concluded that there is no substantial advantage to using zinc therapy over placebo for people dealing with chronic cough, and suggest that larger trials are unnecessary at this time.
Our group included 34 participants who were primarily white females suffering from moderate to severe cough. Throughout the trial, we noted that those taking zinc acetate did experience a rise in serum zinc levels, which indicates that the treatment was effective in that regard. However, when assessing the overall impact on cough symptoms and quality of life, both the zinc and placebo groups showed improvements, but those improvements were minimal.
Importantly, the treatment effects observed did not reach the clinically meaningful thresholds that would suggest zinc acetate significantly benefits cough management. Therefore, we concluded that there is no substantial advantage to using zinc therapy over placebo for people dealing with chronic cough, and suggest that larger trials are unnecessary at this time.
Read More
9
Zinc therapy shows promise for cough
We explored the effectiveness of Epipharyngeal Abrasive Therapy (EAT) in addressing chronic cough, particularly in the context of Long COVID. This treatment, prevalent in Japan, uses zinc chloride to reduce inflammation in the epipharyngeal mucosa. We followed a 21-year-old man whose chronic cough persisted for four months after a mild COVID-19 infection. Upon diagnosis, we identified chronic epipharyngitis as the culprit behind his ongoing cough.
The EAT involved weekly treatments for three months. We observed that this therapy not only cleared residual SARS-CoV-2 spike RNA from the epipharyngeal mucosa but also led to a decrease in inflammation and proinflammatory cytokines. While the application of zinc chloride was a significant part of the treatment, it was combined with other elements of EAT, making it challenging to isolate zinc's specific impact on cough relief.
Overall, we found that EAT could be a promising avenue for individuals suffering from chronic cough related to Long COVID, highlighting an innovative way to utilize zinc in managing this persistent symptom.
The EAT involved weekly treatments for three months. We observed that this therapy not only cleared residual SARS-CoV-2 spike RNA from the epipharyngeal mucosa but also led to a decrease in inflammation and proinflammatory cytokines. While the application of zinc chloride was a significant part of the treatment, it was combined with other elements of EAT, making it challenging to isolate zinc's specific impact on cough relief.
Overall, we found that EAT could be a promising avenue for individuals suffering from chronic cough related to Long COVID, highlighting an innovative way to utilize zinc in managing this persistent symptom.
Read More
8
We conducted a rigorous randomized controlled trial to evaluate the effectiveness of an innovative treatment involving a combination of two tablets: one with Aspirin and Promethazine, and another packed with essential micronutrients like vitamin D3, C, B3, zinc, and selenium. Our aim was to determine how this combination affects the symptoms of mild to moderate COVID-19, particularly cough.
Our study included 260 patients and followed a strict methodology, comparing this new treatment to the standard clinical management recommended by the Indian Council of Medical Research. Over a treatment period of 10 days, we observed notable improvements in symptoms, including cough, myalgia, headache, and anosmia, among those who received the APMV2020 treatment alongside standard care.
While zinc was included in the treatment, this study does not isolate its effect on cough specifically since it was part of a comprehensive combination. However, our findings indicated that APMV2020 treatment led to a significant reduction in cough symptoms and inflammatory markers. This positions APMV2020 as a promising candidate for inclusion in COVID-19 management protocols, not only for rapid recovery but also for its potential long-term benefits in reducing complications associated with the virus.
Our study included 260 patients and followed a strict methodology, comparing this new treatment to the standard clinical management recommended by the Indian Council of Medical Research. Over a treatment period of 10 days, we observed notable improvements in symptoms, including cough, myalgia, headache, and anosmia, among those who received the APMV2020 treatment alongside standard care.
While zinc was included in the treatment, this study does not isolate its effect on cough specifically since it was part of a comprehensive combination. However, our findings indicated that APMV2020 treatment led to a significant reduction in cough symptoms and inflammatory markers. This positions APMV2020 as a promising candidate for inclusion in COVID-19 management protocols, not only for rapid recovery but also for its potential long-term benefits in reducing complications associated with the virus.
Read More
Most Useful Reviews
9
No cough symptoms
203 people found this helpful
A fantastic product! As soon as I notice the first signs of a cold, I administer it to my child, and by the following day, there is no coughing or sneezing.
Read More
9
Cough relief observed
142 people found this helpful
This is a superb remedy for colds. Previously, I used elderberry syrup alone and was very happy with it, but this one has added vitamin C and zinc, which significantly boosts immunity. I give it to my seven-year-old daughter at the onset of a cold, and the results are clearly observable. The initial signs of a cold and a developing cough vanished within three days. Although there was a slight cough and minor throat redness, there was no fever. The syrup is also quite palatable for children, making it easy to administer.
Read More
9
Cough disappears quickly
121 people found this helpful
A brilliant solution! If I see early signs of a cold, I give my child 5 ml daily, and by the following day, there are no coughing or sneezing. I will certainly reorder.
Read More
Medical Researches
SCIENTIFIC SCORE
Questionable
Based on 4 Researches
6.5
- All Researches
9
Zinc therapy shows promise for cough
We explored the effectiveness of Epipharyngeal Abrasive Therapy (EAT) in addressing chronic cough, particularly in the context of Long COVID. This treatment, prevalent in Japan, uses zinc chloride to reduce inflammation in the epipharyngeal mucosa. We followed a 21-year-old man whose chronic cough persisted for four months after a mild COVID-19 infection. Upon diagnosis, we identified chronic epipharyngitis as the culprit behind his ongoing cough.
The EAT involved weekly treatments for three months. We observed that this therapy not only cleared residual SARS-CoV-2 spike RNA from the epipharyngeal mucosa but also led to a decrease in inflammation and proinflammatory cytokines. While the application of zinc chloride was a significant part of the treatment, it was combined with other elements of EAT, making it challenging to isolate zinc's specific impact on cough relief.
Overall, we found that EAT could be a promising avenue for individuals suffering from chronic cough related to Long COVID, highlighting an innovative way to utilize zinc in managing this persistent symptom.
The EAT involved weekly treatments for three months. We observed that this therapy not only cleared residual SARS-CoV-2 spike RNA from the epipharyngeal mucosa but also led to a decrease in inflammation and proinflammatory cytokines. While the application of zinc chloride was a significant part of the treatment, it was combined with other elements of EAT, making it challenging to isolate zinc's specific impact on cough relief.
Overall, we found that EAT could be a promising avenue for individuals suffering from chronic cough related to Long COVID, highlighting an innovative way to utilize zinc in managing this persistent symptom.
Read More
8
We conducted a rigorous randomized controlled trial to evaluate the effectiveness of an innovative treatment involving a combination of two tablets: one with Aspirin and Promethazine, and another packed with essential micronutrients like vitamin D3, C, B3, zinc, and selenium. Our aim was to determine how this combination affects the symptoms of mild to moderate COVID-19, particularly cough.
Our study included 260 patients and followed a strict methodology, comparing this new treatment to the standard clinical management recommended by the Indian Council of Medical Research. Over a treatment period of 10 days, we observed notable improvements in symptoms, including cough, myalgia, headache, and anosmia, among those who received the APMV2020 treatment alongside standard care.
While zinc was included in the treatment, this study does not isolate its effect on cough specifically since it was part of a comprehensive combination. However, our findings indicated that APMV2020 treatment led to a significant reduction in cough symptoms and inflammatory markers. This positions APMV2020 as a promising candidate for inclusion in COVID-19 management protocols, not only for rapid recovery but also for its potential long-term benefits in reducing complications associated with the virus.
Our study included 260 patients and followed a strict methodology, comparing this new treatment to the standard clinical management recommended by the Indian Council of Medical Research. Over a treatment period of 10 days, we observed notable improvements in symptoms, including cough, myalgia, headache, and anosmia, among those who received the APMV2020 treatment alongside standard care.
While zinc was included in the treatment, this study does not isolate its effect on cough specifically since it was part of a comprehensive combination. However, our findings indicated that APMV2020 treatment led to a significant reduction in cough symptoms and inflammatory markers. This positions APMV2020 as a promising candidate for inclusion in COVID-19 management protocols, not only for rapid recovery but also for its potential long-term benefits in reducing complications associated with the virus.
Read More
In our recent study, we investigated the potential benefits of a natural preparation called Inflaminat, which includes black elderberry, violet herb, and calendula flowers, on cough and other symptoms of chronic obstructive pulmonary disease (COPD). Conducted over six months, this randomized double-blind placebo-controlled trial involved 60 patients with moderate COPD.
We observed that those taking Inflaminat experienced a significant improvement in their symptoms as measured by the Breathlessness, Cough, and Sputum Scale. Specifically, their scores decreased from an average of 3.0 to 1.9, indicating less breathlessness and fewer cough symptoms. Additionally, their lung function improved, with a marked increase in the FEV1 measurement from 66% to 73%.
Importantly, participants in the placebo group showed no similar improvements, reinforcing the effectiveness of the natural remedy. Furthermore, we found no side effects associated with the preparation. Our findings suggest that herbal remedies, particularly those containing elderberry, could be valuable in alleviating cough and improving respiratory function in patients suffering from COPD.
We observed that those taking Inflaminat experienced a significant improvement in their symptoms as measured by the Breathlessness, Cough, and Sputum Scale. Specifically, their scores decreased from an average of 3.0 to 1.9, indicating less breathlessness and fewer cough symptoms. Additionally, their lung function improved, with a marked increase in the FEV1 measurement from 66% to 73%.
Importantly, participants in the placebo group showed no similar improvements, reinforcing the effectiveness of the natural remedy. Furthermore, we found no side effects associated with the preparation. Our findings suggest that herbal remedies, particularly those containing elderberry, could be valuable in alleviating cough and improving respiratory function in patients suffering from COPD.
Read More
2
We conducted a pilot trial to explore the effectiveness of zinc acetate in treating chronic refractory cough, a condition that causes significant discomfort for many people. In this study, we compared zinc acetate against a placebo over a period of six weeks, with the aim of measuring improvements in quality of life and cough symptoms using several established questionnaires.
Our group included 34 participants who were primarily white females suffering from moderate to severe cough. Throughout the trial, we noted that those taking zinc acetate did experience a rise in serum zinc levels, which indicates that the treatment was effective in that regard. However, when assessing the overall impact on cough symptoms and quality of life, both the zinc and placebo groups showed improvements, but those improvements were minimal.
Importantly, the treatment effects observed did not reach the clinically meaningful thresholds that would suggest zinc acetate significantly benefits cough management. Therefore, we concluded that there is no substantial advantage to using zinc therapy over placebo for people dealing with chronic cough, and suggest that larger trials are unnecessary at this time.
Our group included 34 participants who were primarily white females suffering from moderate to severe cough. Throughout the trial, we noted that those taking zinc acetate did experience a rise in serum zinc levels, which indicates that the treatment was effective in that regard. However, when assessing the overall impact on cough symptoms and quality of life, both the zinc and placebo groups showed improvements, but those improvements were minimal.
Importantly, the treatment effects observed did not reach the clinically meaningful thresholds that would suggest zinc acetate significantly benefits cough management. Therefore, we concluded that there is no substantial advantage to using zinc therapy over placebo for people dealing with chronic cough, and suggest that larger trials are unnecessary at this time.
Read More
User Reviews
USERS' SCORE
Good
Based on 85 Reviews
8.7
- All Reviews
- Positive Reviews
- Negative Reviews
9
No cough symptoms
203 people found this helpful
A fantastic product! As soon as I notice the first signs of a cold, I administer it to my child, and by the following day, there is no coughing or sneezing.
Read More
9
Cough relief observed
142 people found this helpful
This is a superb remedy for colds. Previously, I used elderberry syrup alone and was very happy with it, but this one has added vitamin C and zinc, which significantly boosts immunity. I give it to my seven-year-old daughter at the onset of a cold, and the results are clearly observable. The initial signs of a cold and a developing cough vanished within three days. Although there was a slight cough and minor throat redness, there was no fever. The syrup is also quite palatable for children, making it easy to administer.
Read More
9
Cough disappears quickly
121 people found this helpful
A brilliant solution! If I see early signs of a cold, I give my child 5 ml daily, and by the following day, there are no coughing or sneezing. I will certainly reorder.
Read More
7.5
Cough reduced significantly
10 people found this helpful
My five-year-old daughter has had continuous illnesses from kindergarten. For about 1-1.5 years, her cough would persist long after recovery. After consulting a paediatrician, I was advised to use Sambucol, and we only needed three days to see a marked reduction in cough frequency. She finds the taste sour, so I dilute it, but she drinks it well. This will now be a staple in my first-aid kit, especially during the cold season. It is a bit pricey, but it works.
Read More
9
Great for immunity
8 people found this helpful
I find this elderberry syrup to be very effective; I give it to my whole family at the first signs of ARVI. It helps prevent illness. The inclusion of zinc and vitamin C is excellent for boosting immunity, and it effectively tackles coughs. The child tolerates it well, and it tastes great.
Read More
Frequently Asked Questions
9
No cough symptoms
203 people found this helpful
A fantastic product! As soon as I notice the first signs of a cold, I administer it to my child, and by the following day, there is no coughing or sneezing.
7.5
Cough reduced significantly
10 people found this helpful
My five-year-old daughter has had continuous illnesses from kindergarten. For about 1-1.5 years, her cough would persist long after recovery. After consulting a paediatrician, I was advised to use Sambucol, and we only needed three days to see a marked reduction in cough frequency. She finds the taste sour, so I dilute it, but she drinks it well. This will now be a staple in my first-aid kit, especially during the cold season. It is a bit pricey, but it works.
10
Highly effective remedy
SAMBUCOL is the best! This antiviral solution is a staple in our medicine cabinet. At the first signs of a cold, I give it to my kids. By the second or third day, cough and snot completely cease! The combination of Sambucol, zinc, and vitamin C is remarkably effective! A resounding 10 out of 10! If you haven't bought it yet, do so—you won't regret it!
9
Cough relief observed
142 people found this helpful
This is a superb remedy for colds. Previously, I used elderberry syrup alone and was very happy with it, but this one has added vitamin C and zinc, which significantly boosts immunity. I give it to my seven-year-old daughter at the onset of a cold, and the results are clearly observable. The initial signs of a cold and a developing cough vanished within three days. Although there was a slight cough and minor throat redness, there was no fever. The syrup is also quite palatable for children, making it easy to administer.
9
Effective for mucus
1 people found this helpful
A friend recommended elderberry to me. I previously had mucus build-up and nighttime coughing, but this product has significantly reduced both. Each day, my coughing and mucus improve, and I feel my immune system getting stronger. I’m a customer for life!
9.5
Stops cough quickly
An excellent tool! This remedy for colds is fantastic. Previously, I bought elderberry syrup and was very pleased, but this version includes vitamin C and zinc, which further boosts the immune system. I give it to my seven-year-old at the first signs of a cold, and the cough simply vanished within three days. There was mild cough and slight throat irritation, but no fever. The syrup's pleasant taste makes it easy for children to take.
9
Cough disappears quickly
121 people found this helpful
A brilliant solution! If I see early signs of a cold, I give my child 5 ml daily, and by the following day, there are no coughing or sneezing. I will certainly reorder.
2
We conducted a pilot trial to explore the effectiveness of zinc acetate in treating chronic refractory cough, a condition that causes significant discomfort for many people. In this study, we compared zinc acetate against a placebo over a period of six weeks, with the aim of measuring improvements in quality of life and cough symptoms using several established questionnaires.
Our group included 34 participants who were primarily white females suffering from moderate to severe cough. Throughout the trial, we noted that those taking zinc acetate did experience a rise in serum zinc levels, which indicates that the treatment was effective in that regard. However, when assessing the overall impact on cough symptoms and quality of life, both the zinc and placebo groups showed improvements, but those improvements were minimal.
Importantly, the treatment effects observed did not reach the clinically meaningful thresholds that would suggest zinc acetate significantly benefits cough management. Therefore, we concluded that there is no substantial advantage to using zinc therapy over placebo for people dealing with chronic cough, and suggest that larger trials are unnecessary at this time.
Our group included 34 participants who were primarily white females suffering from moderate to severe cough. Throughout the trial, we noted that those taking zinc acetate did experience a rise in serum zinc levels, which indicates that the treatment was effective in that regard. However, when assessing the overall impact on cough symptoms and quality of life, both the zinc and placebo groups showed improvements, but those improvements were minimal.
Importantly, the treatment effects observed did not reach the clinically meaningful thresholds that would suggest zinc acetate significantly benefits cough management. Therefore, we concluded that there is no substantial advantage to using zinc therapy over placebo for people dealing with chronic cough, and suggest that larger trials are unnecessary at this time.
9
Zinc therapy shows promise for cough
We explored the effectiveness of Epipharyngeal Abrasive Therapy (EAT) in addressing chronic cough, particularly in the context of Long COVID. This treatment, prevalent in Japan, uses zinc chloride to reduce inflammation in the epipharyngeal mucosa. We followed a 21-year-old man whose chronic cough persisted for four months after a mild COVID-19 infection. Upon diagnosis, we identified chronic epipharyngitis as the culprit behind his ongoing cough.
The EAT involved weekly treatments for three months. We observed that this therapy not only cleared residual SARS-CoV-2 spike RNA from the epipharyngeal mucosa but also led to a decrease in inflammation and proinflammatory cytokines. While the application of zinc chloride was a significant part of the treatment, it was combined with other elements of EAT, making it challenging to isolate zinc's specific impact on cough relief.
Overall, we found that EAT could be a promising avenue for individuals suffering from chronic cough related to Long COVID, highlighting an innovative way to utilize zinc in managing this persistent symptom.
The EAT involved weekly treatments for three months. We observed that this therapy not only cleared residual SARS-CoV-2 spike RNA from the epipharyngeal mucosa but also led to a decrease in inflammation and proinflammatory cytokines. While the application of zinc chloride was a significant part of the treatment, it was combined with other elements of EAT, making it challenging to isolate zinc's specific impact on cough relief.
Overall, we found that EAT could be a promising avenue for individuals suffering from chronic cough related to Long COVID, highlighting an innovative way to utilize zinc in managing this persistent symptom.
In our recent study, we investigated the potential benefits of a natural preparation called Inflaminat, which includes black elderberry, violet herb, and calendula flowers, on cough and other symptoms of chronic obstructive pulmonary disease (COPD). Conducted over six months, this randomized double-blind placebo-controlled trial involved 60 patients with moderate COPD.
We observed that those taking Inflaminat experienced a significant improvement in their symptoms as measured by the Breathlessness, Cough, and Sputum Scale. Specifically, their scores decreased from an average of 3.0 to 1.9, indicating less breathlessness and fewer cough symptoms. Additionally, their lung function improved, with a marked increase in the FEV1 measurement from 66% to 73%.
Importantly, participants in the placebo group showed no similar improvements, reinforcing the effectiveness of the natural remedy. Furthermore, we found no side effects associated with the preparation. Our findings suggest that herbal remedies, particularly those containing elderberry, could be valuable in alleviating cough and improving respiratory function in patients suffering from COPD.
We observed that those taking Inflaminat experienced a significant improvement in their symptoms as measured by the Breathlessness, Cough, and Sputum Scale. Specifically, their scores decreased from an average of 3.0 to 1.9, indicating less breathlessness and fewer cough symptoms. Additionally, their lung function improved, with a marked increase in the FEV1 measurement from 66% to 73%.
Importantly, participants in the placebo group showed no similar improvements, reinforcing the effectiveness of the natural remedy. Furthermore, we found no side effects associated with the preparation. Our findings suggest that herbal remedies, particularly those containing elderberry, could be valuable in alleviating cough and improving respiratory function in patients suffering from COPD.
References
- Balasubramanian A, Holbrook JT, Canning BJ, Que LG, Castro M, et al. Efficacy and tolerability of zinc acetate for treatment of chronic refractory cough: pilot randomised futility trial. ERJ Open Res. 2023;9. 10.1183/23120541.00678-2022
- Nishi K, Yoshimoto S, Tanaka T, Kimura S, Shinchi Y, et al. A Potential Novel Treatment for Chronic Cough in Long COVID Patients: Clearance of Epipharyngeal Residual SARS-CoV-2 Spike RNA by Epipharyngeal Abrasive Therapy. Cureus. 2023;15:e33421. 10.7759/cureus.33421
- Kumar GS, Vadgaonkar A, Purunaik S, Shelatkar R, Vaidya VG, et al. Efficacy and Safety of Aspirin, Promethazine, and Micronutrients for Rapid Clinical Recovery in Mild to Moderate COVID-19 Patients: A Randomized Controlled Clinical Trial. Cureus. 2022;14:e25467. 10.7759/cureus.25467
- Kirichenko TV, Sobenin IA, Markina YV, Gerasimova EV, Grechko AV, et al. Clinical Effectiveness of a Combination of Black Elder Berries, Violet Herb, and Calendula Flowers in Chronic Obstructive Pulmonary Disease: The Results of a Double-Blinded Placebo-Controlled Study. Biology (Basel). 2020;9. 10.3390/biology9040083
