5/17/2025
Overview
SCIENTIFIC SCORE
Likely Very Effective
Based on 1 Research
9
USERS' SCORE
Good
Based on 1 Review
8.5
Top Medical Research Studies
9
We explored the impact of iron on chemotherapy effectiveness, particularly in the treatment of osteosarcoma (OS). The study revealed promising insights into how combining iron with eriodictyol and cisplatin could promote ferroptosis—a form of regulated cell death that can improve the overall effectiveness of cancer therapies.
The researchers discovered that eriodictyol can curb a protein known as BACH1, which leads to reduced production of GPX4, a key player in protecting cells from ferroptosis. By diminishing GPX4 levels, this combination appears to push cancer cells towards ferroptosis more effectively.
Moreover, employing hollow mesoporous nanocubes to deliver eriodictyol and cisplatin seamlessly combines these agents to enhance cell death in OS. Through multiple mechanisms, including the depletion of protective molecules and the direct initiation of fatal processes in cancer cells, the nanocomplex showed impressive results in both lab tests and animal studies.
Importantly, the treatment demonstrated effectiveness without causing significant harm to other organs, hinting at its potential as a therapeutic strategy for OS patients in need of better treatment options.
The researchers discovered that eriodictyol can curb a protein known as BACH1, which leads to reduced production of GPX4, a key player in protecting cells from ferroptosis. By diminishing GPX4 levels, this combination appears to push cancer cells towards ferroptosis more effectively.
Moreover, employing hollow mesoporous nanocubes to deliver eriodictyol and cisplatin seamlessly combines these agents to enhance cell death in OS. Through multiple mechanisms, including the depletion of protective molecules and the direct initiation of fatal processes in cancer cells, the nanocomplex showed impressive results in both lab tests and animal studies.
Importantly, the treatment demonstrated effectiveness without causing significant harm to other organs, hinting at its potential as a therapeutic strategy for OS patients in need of better treatment options.
Read More
Most Useful Reviews
9
Effective iron levels
5 people found this helpful
Following my chemotherapy, my blood counts dropped dangerously low, resulting in frequent collapses. I remembered taking these iron pills before when diagnosed with celiac disease, and they WORK! After using them, my haemoglobin levels increased significantly.
Read More
Medical Researches
SCIENTIFIC SCORE
Likely Very Effective
Based on 1 Research
9
- All Researches
9
We explored the impact of iron on chemotherapy effectiveness, particularly in the treatment of osteosarcoma (OS). The study revealed promising insights into how combining iron with eriodictyol and cisplatin could promote ferroptosis—a form of regulated cell death that can improve the overall effectiveness of cancer therapies.
The researchers discovered that eriodictyol can curb a protein known as BACH1, which leads to reduced production of GPX4, a key player in protecting cells from ferroptosis. By diminishing GPX4 levels, this combination appears to push cancer cells towards ferroptosis more effectively.
Moreover, employing hollow mesoporous nanocubes to deliver eriodictyol and cisplatin seamlessly combines these agents to enhance cell death in OS. Through multiple mechanisms, including the depletion of protective molecules and the direct initiation of fatal processes in cancer cells, the nanocomplex showed impressive results in both lab tests and animal studies.
Importantly, the treatment demonstrated effectiveness without causing significant harm to other organs, hinting at its potential as a therapeutic strategy for OS patients in need of better treatment options.
The researchers discovered that eriodictyol can curb a protein known as BACH1, which leads to reduced production of GPX4, a key player in protecting cells from ferroptosis. By diminishing GPX4 levels, this combination appears to push cancer cells towards ferroptosis more effectively.
Moreover, employing hollow mesoporous nanocubes to deliver eriodictyol and cisplatin seamlessly combines these agents to enhance cell death in OS. Through multiple mechanisms, including the depletion of protective molecules and the direct initiation of fatal processes in cancer cells, the nanocomplex showed impressive results in both lab tests and animal studies.
Importantly, the treatment demonstrated effectiveness without causing significant harm to other organs, hinting at its potential as a therapeutic strategy for OS patients in need of better treatment options.
Read More
User Reviews
USERS' SCORE
Good
Based on 1 Review
8.5
- All Reviews
- Positive Reviews
- Negative Reviews
9
Effective iron levels
5 people found this helpful
Following my chemotherapy, my blood counts dropped dangerously low, resulting in frequent collapses. I remembered taking these iron pills before when diagnosed with celiac disease, and they WORK! After using them, my haemoglobin levels increased significantly.
Read More
Frequently Asked Questions
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References
- Lin Z, Li Y, Wu Z, Liu Q, Li X, et al. Eriodictyol-cisplatin coated nanomedicine synergistically promote osteosarcoma cells ferroptosis and chemosensitivity. J Nanobiotechnology. 2025;23:109. 10.1186/s12951-025-03206-3
