Overview

SCIENTIFIC SCORE
Possibly Effective
Based on 11 Researches
7.9
USERS' SCORE
Good
Based on 5 Reviews
8.6
Supplement Facts
Serving Size: 2 VegCaps
Serving Per Container: 125
Amount Per Serving
%DV
Vitamin C (As ascorbic Acid, Rose Hips, Acerola Cherry)
1,000 mg
1,111%
Bioflavonoid Concentrate (From Lemon)
500 mg
*
Rutin Concentrate
100 mg
*
Hesperidin Concentrate
100 mg
*
Citrus Pectin
30 mg
*

Top Medical Research Studies

We observed an intriguing case involving a 4.5-year-old boy who developed significant knee pain due to a rare nutritional deficiency, scurvy. This condition stemmed from his exclusive intake of meat over the past two years, resulting in skeletal issues and inflammation in multiple joints, including his knees.

Upon examination, the child exhibited several symptoms, including pain, swelling, and an inability to walk. Standard blood tests primarily indicated anemia, but X-rays revealed alarming conditions related to scurvy, such as delayed bone age and severe osteopenia. This alarming picture led us to the conclusion that vitamin C deficiency was the underlying culprit behind his knee pain and skeletal issues.

After initiating vitamin C therapy, we noted a remarkable reduction in pain and swelling over the next two months. The child’s condition improved significantly, allowing him to walk again, and follow-up X-rays confirmed the positive changes in his bone health. This case clearly illustrates how vitamin C can effectively alleviate knee pain related to scurvy and reinforces the importance of proper nutrition for overall skeletal health.
Read More
We observed a case involving a man in his 60s with a history of head and neck cancer who presented with unexplained pain in his left knee and bruising in both his upper and lower limbs, symptoms that had been ongoing for about three weeks. Further tests revealed that his blood showed signs of normocytic anemia and slightly abnormal clotting, yet no major inflammatory issues were found.

Upon examination of his knee, we found blood in the joint, known as haemarthrosis, and a crucial lab test indicated that he had an undetectable level of vitamin C in his blood. This led to a diagnosis of scurvy, a condition caused by severe vitamin C deficiency, which we identified as the underlying reason for his joint bleeding.

After starting vitamin C supplementation along with dietary changes and managing his pain with acetaminophen, the patient's vitamin C levels returned to normal. Excitingly, his knee pain and swelling improved significantly. This case sheds light on scurvy as a rare but important cause of knee pain and discomfort, especially in patients at risk, showing that effective treatment is available.
Read More
We designed a prospective randomized study to explore how vitamin C may prevent complex regional pain syndrome (CRPS) in patients recovering from total knee arthroplasty (TKA). This condition often manifests after surgery, causing persistent pain that can severely affect recovery. To evaluate vitamin C's effectiveness, we compared one group of patients receiving vitamin C to another group that did not.

During the research, we included a total of 292 patients, with 153 in the vitamin C group and 139 in the control group. We tracked the incidence of CRPS, applying both the Budapest criteria and bone scintigraphy to make accurate diagnoses.

Our findings revealed a significant difference: only 3.9% of patients in the vitamin C group developed CRPS, compared to 12.2% in the control group. This led us to conclude that taking 1 gram of vitamin C daily for 40 days following TKA can effectively reduce the risk of developing CRPS.

In simple terms, it appears that vitamin C can serve as a valuable preventive measure against chronic pain after knee surgery, providing hope for those aiming to recover smoothly.
Read More

Most Useful Reviews

9.5
Supports knee pain
I specifically purchased this Vitamin C alongside diosmin (Detralex) to aid my veins. It's very effective, alleviating pain and swelling in my legs, including my knee pain.
Read More
9.5
No knee pain
I provided this to my parents suffering from a sensitive stomach, and they can take these vitamin seeds without any stomach pain, which is a relief.
Read More
7.5
Reduced painkillers
After adjusting my intake, I realised I miscalculated the dosage. I've been taking high doses of Vitamin C for knee pain management, and it seems to have helped reduce my reliance on painkillers like loxonin significantly. I hope to reduce my dosage further.
Read More

Medical Researches

SCIENTIFIC SCORE
Possibly Effective
Based on 11 Researches
7.9
  • All Researches
9.5
Vitamin C improves knee pain
We observed a fascinating case involving a previously healthy three-year-old boy who presented with acute knee pain. Initially, his doctors diagnosed him with transient synovitis, assuming this common condition would resolve on its own. However, the situation took a turn when he returned with worsening pain and new symptoms, including a rash and significant bruising.

Through careful examination and testing, we identified that the root cause of his discomfort was vitamin C deficiency, likely due to inadequate dietary intake. This finding was confirmed through blood tests, leading to a targeted treatment with oral vitamin C.

Within six weeks of starting the vitamin C supplementation, we noted a remarkable turnaround in his health. His knee pain and other symptoms nearly vanished as he engaged in a balanced diet to prevent future deficiencies. This case highlights the important connection between vitamin C levels and joint health, reminding us how critical nutrition is to overall well-being, especially in children.
Read More
We examined the potential benefits of high-dose intravenous vitamin C for relieving knee pain in a patient suffering from Chikungunya fever. The patient, a 54-year-old Hispanic individual, reported symptoms that included left shoulder and knee pain along with fever. Symptoms began abruptly during the night on a Saturday in September 2014.

The treatment involved administering high doses of vitamin C over two days. Remarkably, after the infusion, the patient's symptoms resolved without experiencing any side effects. This case suggests that intravenous vitamin C could be a promising treatment option for those suffering from acute viral infections and associated knee pain.

While this study is intriguing and highlights a potential treatment avenue, further research is needed to conclusively establish the effects of vitamin C on knee pain, specifically in the context of viral infections.
Read More
We observed a case involving a man in his 60s with a history of head and neck cancer who presented with unexplained pain in his left knee and bruising in both his upper and lower limbs, symptoms that had been ongoing for about three weeks. Further tests revealed that his blood showed signs of normocytic anemia and slightly abnormal clotting, yet no major inflammatory issues were found.

Upon examination of his knee, we found blood in the joint, known as haemarthrosis, and a crucial lab test indicated that he had an undetectable level of vitamin C in his blood. This led to a diagnosis of scurvy, a condition caused by severe vitamin C deficiency, which we identified as the underlying reason for his joint bleeding.

After starting vitamin C supplementation along with dietary changes and managing his pain with acetaminophen, the patient's vitamin C levels returned to normal. Excitingly, his knee pain and swelling improved significantly. This case sheds light on scurvy as a rare but important cause of knee pain and discomfort, especially in patients at risk, showing that effective treatment is available.
Read More
We designed a prospective randomized study to explore how vitamin C may prevent complex regional pain syndrome (CRPS) in patients recovering from total knee arthroplasty (TKA). This condition often manifests after surgery, causing persistent pain that can severely affect recovery. To evaluate vitamin C's effectiveness, we compared one group of patients receiving vitamin C to another group that did not.

During the research, we included a total of 292 patients, with 153 in the vitamin C group and 139 in the control group. We tracked the incidence of CRPS, applying both the Budapest criteria and bone scintigraphy to make accurate diagnoses.

Our findings revealed a significant difference: only 3.9% of patients in the vitamin C group developed CRPS, compared to 12.2% in the control group. This led us to conclude that taking 1 gram of vitamin C daily for 40 days following TKA can effectively reduce the risk of developing CRPS.

In simple terms, it appears that vitamin C can serve as a valuable preventive measure against chronic pain after knee surgery, providing hope for those aiming to recover smoothly.
Read More
We observed an intriguing case involving a 4.5-year-old boy who developed significant knee pain due to a rare nutritional deficiency, scurvy. This condition stemmed from his exclusive intake of meat over the past two years, resulting in skeletal issues and inflammation in multiple joints, including his knees.

Upon examination, the child exhibited several symptoms, including pain, swelling, and an inability to walk. Standard blood tests primarily indicated anemia, but X-rays revealed alarming conditions related to scurvy, such as delayed bone age and severe osteopenia. This alarming picture led us to the conclusion that vitamin C deficiency was the underlying culprit behind his knee pain and skeletal issues.

After initiating vitamin C therapy, we noted a remarkable reduction in pain and swelling over the next two months. The child’s condition improved significantly, allowing him to walk again, and follow-up X-rays confirmed the positive changes in his bone health. This case clearly illustrates how vitamin C can effectively alleviate knee pain related to scurvy and reinforces the importance of proper nutrition for overall skeletal health.
Read More

User Reviews

USERS' SCORE
Good
Based on 5 Reviews
8.6
  • All Reviews
  • Positive Reviews
  • Negative Reviews
9.5
Supports knee pain
I specifically purchased this Vitamin C alongside diosmin (Detralex) to aid my veins. It's very effective, alleviating pain and swelling in my legs, including my knee pain.
Read More
9.5
No knee pain
I provided this to my parents suffering from a sensitive stomach, and they can take these vitamin seeds without any stomach pain, which is a relief.
Read More
7.5
Reduced painkillers
After adjusting my intake, I realised I miscalculated the dosage. I've been taking high doses of Vitamin C for knee pain management, and it seems to have helped reduce my reliance on painkillers like loxonin significantly. I hope to reduce my dosage further.
Read More
8.8
Reduced knee pain
I find it quite effective. I take the liquid liposome Vitamin C multiple times daily when I'm unwell, particularly for my rheumatoid arthritis, as insufficient Vitamin C leads to knee pain.
Read More
8.8
Improves knee pain
This Vitamin C is beneficial for my veins. My mother has noticed less discomfort around her knee, and we take it each evening.
Read More

Frequently Asked Questions

Knee pain is a common condition that can result from various causes, including injuries, overuse, and underlying medical conditions such as arthritis. The knee joint is a complex structure composed of bones, ligaments, tendons, and cartilage, all of which work together to enable movement and support body weight. When any of these components are damaged or inflamed, it can lead to discomfort, stiffness, swelling, and reduced mobility in the affected area.

In many cases, knee pain can manifest as acute pain following an injury, such as a tear in a ligament or cartilage damage. Alternatively, it may develop gradually due to factors like repetitive strain, age-related degeneration, or conditions like osteoarthritis and rheumatoid arthritis. Treatment options vary widely and may include rest, physical therapy, medication, or, in severe cases, surgical interventions. If you're experiencing persistent knee pain, it's advisable to consult with a healthcare professional for an accurate diagnosis and tailored treatment plan.

Vitamin C, also known as ascorbic acid, is a water-soluble vitamin that plays a critical role in numerous bodily functions. As an essential nutrient, it contributes to the growth and repair of tissues in the body, and it is vital for the production of collagen, an important protein that helps maintain skin, cartilage, tendons, ligaments, and blood vessels. Additionally, Vitamin C acts as a powerful antioxidant, which means it helps combat free radicals—unstable molecules that can cause oxidative stress and contribute to various chronic diseases.

Moreover, Vitamin C enhances iron absorption from plant-based foods, making it a vital component for those following vegetarian or vegan diets. While many people get sufficient Vitamin C from a well-balanced diet that includes fruits and vegetables like oranges, strawberries, kiwi, broccoli, and bell peppers, some individuals might require supplementation. It's generally recommended to stay within the daily intake guidelines, as excessive consumption can lead to gastrointestinal disturbances. Overall, Vitamin C is not just a skincare celebrity—it's a fundamental part of maintaining overall health and well-being.

Vitamin C is best known for its role in boosting the immune system, but it also plays a significant part in the health of our joints, including the knees. This essential nutrient aids in the synthesis of collagen, which is crucial for maintaining the integrity of cartilage. Some studies suggest that adequate levels of vitamin C might help reduce inflammation and improve overall joint health, potentially offering relief to those experiencing knee pain associated with osteoarthritis or other conditions.

However, while vitamin C could possibly contribute to joint health, it's important to note that evidence directly linking vitamin C supplementation to reduced knee pain is still limited. Most benefits are seen as indirect through the nutrient's role in collagen formation and its antioxidant properties, which may help combat oxidative stress in joint tissues. If you're considering vitamin C supplements to help with knee pain, it's best to consult a healthcare professional for personalized advice tailored to your specific situation.

Based on user reviews, the timeframe for experiencing relief from knee pain while taking this supplement can vary. Some users have reported noticeable improvements relatively quickly, with one reviewer indicating that their knee pain has significantly decreased after starting the supplement (Read Review). However, the overall consensus suggests that it may take some time to adjust dosages and notice the full effects, with consistent use being important for optimal results.

Additionally, another user mentioned how they've incorporated the supplement into their routine for managing rheumatoid arthritis and noted a profound benefit when Vitamin C levels are maintained (Read Review). While individual responses can vary, many users seem to find improvements within weeks of consistent intake, particularly when used alongside other treatments.

The scientific research surrounding the potential benefits of vitamin C for knee pain presents a mixed picture. While some studies indicate that vitamin C may improve conditions related to knee joint issues, its direct efficacy in alleviating knee pain specifically remains inconclusive. One study involving patients with osteoarthritis noted some improvements when vitamin C was included in a multi-component treatment, but it could not be determined if these benefits were due solely to vitamin C ([2]). Additionally, a randomized controlled trial focusing on athletes with knee pain due to patellar tendinopathy is ongoing, which may shed light on the specific impact of vitamin C in such contexts ([3]).

Some research highlights the role of vitamin C in enhancing recovery after surgeries, potentially reducing postoperative pain and preventing chronic pain conditions such as complex regional pain syndrome ([6]). In certain cases related to vitamin C deficiency, such as scurvy, supplementation has proven effective in resolving knee pain, particularly in individuals whose pain is explicitly linked to nutritional deficiencies ([11]). Overall, while vitamin C may have supportive roles in joint health and recovery, further studies are needed to clarify its specific impact on knee pain.

Based on user reviews, many individuals have reported noteworthy improvements in their symptoms after integrating Vitamin C into their health regimen. Users have mentioned a significant alleviation of pain and swelling in their legs, including knee discomfort, particularly when paired with other treatments such as diosmin (Read Review). One reviewer specifically noted a reduction in dependence on painkillers for knee pain management, attributing it to high doses of Vitamin C (Read Review).

Moreover, consistent intake was emphasized, especially for conditions like rheumatoid arthritis, where maintaining adequate Vitamin C levels has been linked to symptom relief, including reduced knee pain (Read Review). Users reported that their family members also experienced less discomfort, showcasing the potential benefits of this vitamin for various pain-related issues (Read Review). While individual results can vary, the collective feedback indicates that many find Vitamin C helpful in managing discomfort effectively.

Based on user reviews, there is a consensus that combining this vitamin C supplement with other treatments can lead to significant improvements in managing knee pain. For instance, one user specifically noted enhanced relief from knee discomfort when taking vitamin C alongside diosmin, stating it alleviated pain and swelling not only in the legs but also in the knees (Read Review). Another review highlighted the effectiveness of high doses of vitamin C in reducing reliance on painkillers for knee pain management, showcasing its potential synergy with other therapies (Read Review).

Additionally, users reported that maintaining consistent vitamin C intake was crucial for managing conditions such as rheumatoid arthritis, where inadequacy in vitamin C levels has been linked to increased knee pain (Read Review). One reviewer even mentioned an improvement in their mother’s knee discomfort when incorporating this supplement into their routine, indicating that family members might also benefit from this combination approach (Read Review). Overall, the reviews suggest that users have experienced better outcomes in managing knee pain when vitamin C is used in conjunction with other relevant treatments.

Users have reported varying experiences and preferences regarding the right dosage of Vitamin C for treating knee pain. One user noted that after adjusting their intake, they realized they had been taking high doses and found it effective in reducing their reliance on painkillers for knee pain management (Read Review). Another user mentioned taking liquid liposome Vitamin C multiple times daily, particularly emphasizing the supplement's importance in alleviating their rheumatoid arthritis symptoms, which included knee pain (Read Review).

Moreover, some individuals have utilized Vitamin C alongside other treatments, such as diosmin, for better overall efficacy in alleviating pain and swelling in the legs and knees (Read Review). Some users did not report specific dosages but indicated frequent doses at different times of the day for effective results. Overall, while there isn't a definitive recommended dose from the reviews, it seems that higher doses tend to yield better results in managing knee pain, though individual adjustments may be necessary.

7.5
Reduced painkillers
After adjusting my intake, I realised I miscalculated the dosage. I've been taking high doses of Vitamin C for knee pain management, and it seems to have helped reduce my reliance on painkillers like loxonin significantly. I hope to reduce my dosage further.
8.8
Reduced knee pain
I find it quite effective. I take the liquid liposome Vitamin C multiple times daily when I'm unwell, particularly for my rheumatoid arthritis, as insufficient Vitamin C leads to knee pain.
9.5
Supports knee pain
I specifically purchased this Vitamin C alongside diosmin (Detralex) to aid my veins. It's very effective, alleviating pain and swelling in my legs, including my knee pain.
8.8
Improves knee pain
This Vitamin C is beneficial for my veins. My mother has noticed less discomfort around her knee, and we take it each evening.
8
Evaluated Vitamin C's knee pain effects
We explored how Vitamin C might affect knee pain in patients suffering from osteoarthritis. The study involved 60 participants who were experiencing clinical and radiological signs of knee osteoarthritis. Over three months, they took Cartinorm, a supplement that included glucosamine sulfate, chondroitin sulfate, forti gel, and Vitamin C, all aimed at improving their symptoms.

While we noticed improvements in movement, reduced pain, and enhanced daily living activities among the patients, it is important to note that we cannot specifically attribute these benefits to Vitamin C alone. It was included in a treatment that involved multiple components, which means isolating its effect on knee pain isn’t feasible with the current data.

Overall, while the treatment showed positive results, the specific impact of Vitamin C on knee pain remains inconclusive. Thus, further studies are necessary to understand its effectiveness in this context.
5
Vitamin C's potential in knee recovery
We conducted a study to see how vitamin C, combined with hydrolyzed collagen, could help athletes dealing with knee pain, specifically those suffering from patellar tendinopathy, often known as jumper's knee. Our research involved a double-blind, randomized controlled trial, meaning neither the participants nor the researchers knew who was receiving the real treatment or a placebo. This setup helps ensure that our findings are as accurate as possible.

Over the course of 24 weeks,76 athletes participated in a program that included tendon loading exercises. Those in the intervention group received daily doses of 10 grams of hydrolyzed collagen and 40 milligrams of vitamin C, while the control group took a placebo. We measured their knee pain and overall function using the VISA-P score, a tool designed to assess pain and sports participation effectiveness.

With our detailed approach, we aimed to evaluate whether the combination of vitamin C and collagen showed any significant improvement in knee pain compared to just the exercise program alone. While we continue to analyze our data and await conclusive results, the overall study is pioneering in assessing this unique combination for recovery in athletes experiencing knee pain.
We designed a prospective randomized study to explore how vitamin C may prevent complex regional pain syndrome (CRPS) in patients recovering from total knee arthroplasty (TKA). This condition often manifests after surgery, causing persistent pain that can severely affect recovery. To evaluate vitamin C's effectiveness, we compared one group of patients receiving vitamin C to another group that did not.

During the research, we included a total of 292 patients, with 153 in the vitamin C group and 139 in the control group. We tracked the incidence of CRPS, applying both the Budapest criteria and bone scintigraphy to make accurate diagnoses.

Our findings revealed a significant difference: only 3.9% of patients in the vitamin C group developed CRPS, compared to 12.2% in the control group. This led us to conclude that taking 1 gram of vitamin C daily for 40 days following TKA can effectively reduce the risk of developing CRPS.

In simple terms, it appears that vitamin C can serve as a valuable preventive measure against chronic pain after knee surgery, providing hope for those aiming to recover smoothly.
We observed an intriguing case involving a 4.5-year-old boy who developed significant knee pain due to a rare nutritional deficiency, scurvy. This condition stemmed from his exclusive intake of meat over the past two years, resulting in skeletal issues and inflammation in multiple joints, including his knees.

Upon examination, the child exhibited several symptoms, including pain, swelling, and an inability to walk. Standard blood tests primarily indicated anemia, but X-rays revealed alarming conditions related to scurvy, such as delayed bone age and severe osteopenia. This alarming picture led us to the conclusion that vitamin C deficiency was the underlying culprit behind his knee pain and skeletal issues.

After initiating vitamin C therapy, we noted a remarkable reduction in pain and swelling over the next two months. The child’s condition improved significantly, allowing him to walk again, and follow-up X-rays confirmed the positive changes in his bone health. This case clearly illustrates how vitamin C can effectively alleviate knee pain related to scurvy and reinforces the importance of proper nutrition for overall skeletal health.

References

  1. Hosseini-Monfared P, Mirahmadi A, Sarzaeem MM, Pourshahryari S, Aminnia P, et al. Ascorbic Acid Reduces the Blood Boss After Total Knee Arthroplasty: Insights From a Randomized Controlled Trial. Arthroplast Today. 2025;32:101618. doi:10.1016/j.artd.2025.101618
  2. Muftic M, Trifunovic S, Galijasevic K. Evaluation of the Cartinorm Use in the Therapy of Patients with Knee Osteoarthritis. Mater Sociomed. 2024;36:54. doi:10.5455/msm.2024.36.54-58
  3. van Dam L, Terink R, Mensink M, de Vos RJ, Zwerver J. The JUMPFOOD study: additional effect of hydrolyzed collagen and vitamin C to exercise treatment for patellar tendinopathy (jumper's knee) in athletes-study protocol for a double-blind randomized controlled trial. Trials. 2023;24:768. doi:10.1186/s13063-023-07783-2
  4. Ramón R, Holguín E, Chiriboga JD, Rubio N, Ballesteros C, et al. Anti-Inflammatory Effect of Vitamin C during the Postoperative Period in Patients Subjected to Total Knee Arthroplasty: A Randomized Controlled Trial. J Pers Med. 2023;13. doi:10.3390/jpm13091299
  5. Marquardt P, Raman G, Shen YM, Wang DH. Scurvy: a rare cause of haemarthrosis. BMJ Case Rep. 2022;15. doi:10.1136/bcr-2021-244594
  6. Jacques H, Jérôme V, Antoine C, Lucile S, Valérie D, et al. Prospective randomized study of the vitamin C effect on pain and complex pain regional syndrome after total knee arthroplasty. Int Orthop. 2021;45:1155. doi:10.1007/s00264-020-04936-9
  7. Kyprios A. Vitamin C Deficiency Presenting as an Acute Limp in Childhood. Cureus. 2020;12:e9182. doi:10.7759/cureus.9182
  8. Ripani U, Manzarbeitia-Arroba P, Guijarro-Leo S, Urrutia-Graña J, De Masi-De Luca A. Vitamin C May Help to Reduce the Knee's Arthritic Symptoms. Outcomes Assessment of Nutriceutical Therapy. Med Arch. 2019;73:173. doi:10.5455/medarh.2019.73.173-177
  9. López-Vidriero E, Olivé-Vilas R, López-Capapé D, Varela-Sende L, López-Vidriero R, et al. Efficacy and Tolerability of Progen, a Nutritional Supplement Based on Innovative Plasma Proteins, in ACL Reconstruction: A Multicenter Randomized Controlled Trial. Orthop J Sports Med. 2019;7:2325967119827237. doi:10.1177/2325967119827237
  10. Gonzalez MJ, Miranda-Massari JR, Berdiel MJ, Duconge J, Rodríguez-López JL, et al. High Dose Intraveneous Vitamin C and Chikungunya Fever: A Case Report. J Orthomol Med. 2014;29:154.
  11. Noordin S, Baloch N, Salat MS, Rashid Memon A, Ahmad T. Skeletal manifestations of scurvy: a case report from dubai. Case Rep Orthop. 2012;2012:624628. doi:10.1155/2012/624628
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