Reviewed By
Reviewed By
Overview
SCIENTIFIC SCORE
Possibly Effective
Based on 11 Researches
7.9
USERS' SCORE
Good
Based on 5 Reviews
8.3
Supplement Facts
Serving Size: 2 VegCaps
Serving Per Container: 125
Amount Per Serving
%DV
Vitamin C (As ascorbic Acid, Rose Hips, Acerola Cherry)
1,000 mg
1,111%
Bioflavonoid Concentrate (From Lemon)
500 mg
*
Rutin Concentrate
100 mg
*
Hesperidin Concentrate
100 mg
*
Citrus Pectin
30 mg
*
Top Medical Research Studies
9
We observed an intriguing case involving a 4.5-year-old boy who developed significant knee pain due to a rare nutritional deficiency, scurvy. This condition stemmed from his exclusive intake of meat over the past two years, resulting in skeletal issues and inflammation in multiple joints, including his knees.
Upon examination, the child exhibited several symptoms, including pain, swelling, and an inability to walk. Standard blood tests primarily indicated anemia, but X-rays revealed alarming conditions related to scurvy, such as delayed bone age and severe osteopenia. This alarming picture led us to the conclusion that vitamin C deficiency was the underlying culprit behind his knee pain and skeletal issues.
After initiating vitamin C therapy, we noted a remarkable reduction in pain and swelling over the next two months. The child’s condition improved significantly, allowing him to walk again, and follow-up X-rays confirmed the positive changes in his bone health. This case clearly illustrates how vitamin C can effectively alleviate knee pain related to scurvy and reinforces the importance of proper nutrition for overall skeletal health.
Upon examination, the child exhibited several symptoms, including pain, swelling, and an inability to walk. Standard blood tests primarily indicated anemia, but X-rays revealed alarming conditions related to scurvy, such as delayed bone age and severe osteopenia. This alarming picture led us to the conclusion that vitamin C deficiency was the underlying culprit behind his knee pain and skeletal issues.
After initiating vitamin C therapy, we noted a remarkable reduction in pain and swelling over the next two months. The child’s condition improved significantly, allowing him to walk again, and follow-up X-rays confirmed the positive changes in his bone health. This case clearly illustrates how vitamin C can effectively alleviate knee pain related to scurvy and reinforces the importance of proper nutrition for overall skeletal health.
Read More
9
Scurvy causes knee pain improvement
We observed a case involving a man in his 60s with a history of head and neck cancer who presented with unexplained pain in his left knee and bruising in both his upper and lower limbs, symptoms that had been ongoing for about three weeks. Further tests revealed that his blood showed signs of normocytic anemia and slightly abnormal clotting, yet no major inflammatory issues were found.
Upon examination of his knee, we found blood in the joint, known as haemarthrosis, and a crucial lab test indicated that he had an undetectable level of vitamin C in his blood. This led to a diagnosis of scurvy, a condition caused by severe vitamin C deficiency, which we identified as the underlying reason for his joint bleeding.
After starting vitamin C supplementation along with dietary changes and managing his pain with acetaminophen, the patient's vitamin C levels returned to normal. Excitingly, his knee pain and swelling improved significantly. This case sheds light on scurvy as a rare but important cause of knee pain and discomfort, especially in patients at risk, showing that effective treatment is available.
Upon examination of his knee, we found blood in the joint, known as haemarthrosis, and a crucial lab test indicated that he had an undetectable level of vitamin C in his blood. This led to a diagnosis of scurvy, a condition caused by severe vitamin C deficiency, which we identified as the underlying reason for his joint bleeding.
After starting vitamin C supplementation along with dietary changes and managing his pain with acetaminophen, the patient's vitamin C levels returned to normal. Excitingly, his knee pain and swelling improved significantly. This case sheds light on scurvy as a rare but important cause of knee pain and discomfort, especially in patients at risk, showing that effective treatment is available.
Read More
9
We designed a prospective randomized study to explore how vitamin C may prevent complex regional pain syndrome (CRPS) in patients recovering from total knee arthroplasty (TKA). This condition often manifests after surgery, causing persistent pain that can severely affect recovery. To evaluate vitamin C's effectiveness, we compared one group of patients receiving vitamin C to another group that did not.
During the research, we included a total of 292 patients, with 153 in the vitamin C group and 139 in the control group. We tracked the incidence of CRPS, applying both the Budapest criteria and bone scintigraphy to make accurate diagnoses.
Our findings revealed a significant difference: only 3.9% of patients in the vitamin C group developed CRPS, compared to 12.2% in the control group. This led us to conclude that taking 1 gram of vitamin C daily for 40 days following TKA can effectively reduce the risk of developing CRPS.
In simple terms, it appears that vitamin C can serve as a valuable preventive measure against chronic pain after knee surgery, providing hope for those aiming to recover smoothly.
During the research, we included a total of 292 patients, with 153 in the vitamin C group and 139 in the control group. We tracked the incidence of CRPS, applying both the Budapest criteria and bone scintigraphy to make accurate diagnoses.
Our findings revealed a significant difference: only 3.9% of patients in the vitamin C group developed CRPS, compared to 12.2% in the control group. This led us to conclude that taking 1 gram of vitamin C daily for 40 days following TKA can effectively reduce the risk of developing CRPS.
In simple terms, it appears that vitamin C can serve as a valuable preventive measure against chronic pain after knee surgery, providing hope for those aiming to recover smoothly.
Read More
Most Useful Reviews
9
Supports knee pain
I specifically purchased this Vitamin C alongside diosmin (Detralex) to aid my veins. It's very effective, alleviating pain and swelling in my legs, including my knee pain.
Read More
9
No knee pain
I provided this to my parents suffering from a sensitive stomach, and they can take these vitamin seeds without any stomach pain, which is a relief.
Read More
7.5
Reduced painkillers
After adjusting my intake, I realised I miscalculated the dosage. I've been taking high doses of Vitamin C for knee pain management, and it seems to have helped reduce my reliance on painkillers like loxonin significantly. I hope to reduce my dosage further.
Read More
Medical Researches
SCIENTIFIC SCORE
Possibly Effective
Based on 11 Researches
7.9
- All Researches
9.5
We observed a fascinating case involving a previously healthy three-year-old boy who presented with acute knee pain. Initially, his doctors diagnosed him with transient synovitis, assuming this common condition would resolve on its own. However, the situation took a turn when he returned with worsening pain and new symptoms, including a rash and significant bruising.
Through careful examination and testing, we identified that the root cause of his discomfort was vitamin C deficiency, likely due to inadequate dietary intake. This finding was confirmed through blood tests, leading to a targeted treatment with oral vitamin C.
Within six weeks of starting the vitamin C supplementation, we noted a remarkable turnaround in his health. His knee pain and other symptoms nearly vanished as he engaged in a balanced diet to prevent future deficiencies. This case highlights the important connection between vitamin C levels and joint health, reminding us how critical nutrition is to overall well-being, especially in children.
Through careful examination and testing, we identified that the root cause of his discomfort was vitamin C deficiency, likely due to inadequate dietary intake. This finding was confirmed through blood tests, leading to a targeted treatment with oral vitamin C.
Within six weeks of starting the vitamin C supplementation, we noted a remarkable turnaround in his health. His knee pain and other symptoms nearly vanished as he engaged in a balanced diet to prevent future deficiencies. This case highlights the important connection between vitamin C levels and joint health, reminding us how critical nutrition is to overall well-being, especially in children.
Read More
9.5
We examined the potential benefits of high-dose intravenous vitamin C for relieving knee pain in a patient suffering from Chikungunya fever. The patient, a 54-year-old Hispanic individual, reported symptoms that included left shoulder and knee pain along with fever. Symptoms began abruptly during the night on a Saturday in September 2014.
The treatment involved administering high doses of vitamin C over two days. Remarkably, after the infusion, the patient's symptoms resolved without experiencing any side effects. This case suggests that intravenous vitamin C could be a promising treatment option for those suffering from acute viral infections and associated knee pain.
While this study is intriguing and highlights a potential treatment avenue, further research is needed to conclusively establish the effects of vitamin C on knee pain, specifically in the context of viral infections.
The treatment involved administering high doses of vitamin C over two days. Remarkably, after the infusion, the patient's symptoms resolved without experiencing any side effects. This case suggests that intravenous vitamin C could be a promising treatment option for those suffering from acute viral infections and associated knee pain.
While this study is intriguing and highlights a potential treatment avenue, further research is needed to conclusively establish the effects of vitamin C on knee pain, specifically in the context of viral infections.
Read More
9
Scurvy causes knee pain improvement
We observed a case involving a man in his 60s with a history of head and neck cancer who presented with unexplained pain in his left knee and bruising in both his upper and lower limbs, symptoms that had been ongoing for about three weeks. Further tests revealed that his blood showed signs of normocytic anemia and slightly abnormal clotting, yet no major inflammatory issues were found.
Upon examination of his knee, we found blood in the joint, known as haemarthrosis, and a crucial lab test indicated that he had an undetectable level of vitamin C in his blood. This led to a diagnosis of scurvy, a condition caused by severe vitamin C deficiency, which we identified as the underlying reason for his joint bleeding.
After starting vitamin C supplementation along with dietary changes and managing his pain with acetaminophen, the patient's vitamin C levels returned to normal. Excitingly, his knee pain and swelling improved significantly. This case sheds light on scurvy as a rare but important cause of knee pain and discomfort, especially in patients at risk, showing that effective treatment is available.
Upon examination of his knee, we found blood in the joint, known as haemarthrosis, and a crucial lab test indicated that he had an undetectable level of vitamin C in his blood. This led to a diagnosis of scurvy, a condition caused by severe vitamin C deficiency, which we identified as the underlying reason for his joint bleeding.
After starting vitamin C supplementation along with dietary changes and managing his pain with acetaminophen, the patient's vitamin C levels returned to normal. Excitingly, his knee pain and swelling improved significantly. This case sheds light on scurvy as a rare but important cause of knee pain and discomfort, especially in patients at risk, showing that effective treatment is available.
Read More
9
We designed a prospective randomized study to explore how vitamin C may prevent complex regional pain syndrome (CRPS) in patients recovering from total knee arthroplasty (TKA). This condition often manifests after surgery, causing persistent pain that can severely affect recovery. To evaluate vitamin C's effectiveness, we compared one group of patients receiving vitamin C to another group that did not.
During the research, we included a total of 292 patients, with 153 in the vitamin C group and 139 in the control group. We tracked the incidence of CRPS, applying both the Budapest criteria and bone scintigraphy to make accurate diagnoses.
Our findings revealed a significant difference: only 3.9% of patients in the vitamin C group developed CRPS, compared to 12.2% in the control group. This led us to conclude that taking 1 gram of vitamin C daily for 40 days following TKA can effectively reduce the risk of developing CRPS.
In simple terms, it appears that vitamin C can serve as a valuable preventive measure against chronic pain after knee surgery, providing hope for those aiming to recover smoothly.
During the research, we included a total of 292 patients, with 153 in the vitamin C group and 139 in the control group. We tracked the incidence of CRPS, applying both the Budapest criteria and bone scintigraphy to make accurate diagnoses.
Our findings revealed a significant difference: only 3.9% of patients in the vitamin C group developed CRPS, compared to 12.2% in the control group. This led us to conclude that taking 1 gram of vitamin C daily for 40 days following TKA can effectively reduce the risk of developing CRPS.
In simple terms, it appears that vitamin C can serve as a valuable preventive measure against chronic pain after knee surgery, providing hope for those aiming to recover smoothly.
Read More
9
We observed an intriguing case involving a 4.5-year-old boy who developed significant knee pain due to a rare nutritional deficiency, scurvy. This condition stemmed from his exclusive intake of meat over the past two years, resulting in skeletal issues and inflammation in multiple joints, including his knees.
Upon examination, the child exhibited several symptoms, including pain, swelling, and an inability to walk. Standard blood tests primarily indicated anemia, but X-rays revealed alarming conditions related to scurvy, such as delayed bone age and severe osteopenia. This alarming picture led us to the conclusion that vitamin C deficiency was the underlying culprit behind his knee pain and skeletal issues.
After initiating vitamin C therapy, we noted a remarkable reduction in pain and swelling over the next two months. The child’s condition improved significantly, allowing him to walk again, and follow-up X-rays confirmed the positive changes in his bone health. This case clearly illustrates how vitamin C can effectively alleviate knee pain related to scurvy and reinforces the importance of proper nutrition for overall skeletal health.
Upon examination, the child exhibited several symptoms, including pain, swelling, and an inability to walk. Standard blood tests primarily indicated anemia, but X-rays revealed alarming conditions related to scurvy, such as delayed bone age and severe osteopenia. This alarming picture led us to the conclusion that vitamin C deficiency was the underlying culprit behind his knee pain and skeletal issues.
After initiating vitamin C therapy, we noted a remarkable reduction in pain and swelling over the next two months. The child’s condition improved significantly, allowing him to walk again, and follow-up X-rays confirmed the positive changes in his bone health. This case clearly illustrates how vitamin C can effectively alleviate knee pain related to scurvy and reinforces the importance of proper nutrition for overall skeletal health.
Read More
User Reviews
USERS' SCORE
Good
Based on 5 Reviews
8.3
- All Reviews
- Positive Reviews
- Negative Reviews
9
Supports knee pain
I specifically purchased this Vitamin C alongside diosmin (Detralex) to aid my veins. It's very effective, alleviating pain and swelling in my legs, including my knee pain.
Read More
9
No knee pain
I provided this to my parents suffering from a sensitive stomach, and they can take these vitamin seeds without any stomach pain, which is a relief.
Read More
7.5
Reduced painkillers
After adjusting my intake, I realised I miscalculated the dosage. I've been taking high doses of Vitamin C for knee pain management, and it seems to have helped reduce my reliance on painkillers like loxonin significantly. I hope to reduce my dosage further.
Read More
7.5
Reduced knee pain
3 people found this helpful
I find it quite effective. I take the liquid liposome Vitamin C multiple times daily when I'm unwell, particularly for my rheumatoid arthritis, as insufficient Vitamin C leads to knee pain.
Read More
7.5
Improves knee pain
This Vitamin C is beneficial for my veins. My mother has noticed less discomfort around her knee, and we take it each evening.
Read More
Frequently Asked Questions
7.5
Reduced painkillers
After adjusting my intake, I realised I miscalculated the dosage. I've been taking high doses of Vitamin C for knee pain management, and it seems to have helped reduce my reliance on painkillers like loxonin significantly. I hope to reduce my dosage further.
7.5
Reduced knee pain
3 people found this helpful
I find it quite effective. I take the liquid liposome Vitamin C multiple times daily when I'm unwell, particularly for my rheumatoid arthritis, as insufficient Vitamin C leads to knee pain.
9
Supports knee pain
I specifically purchased this Vitamin C alongside diosmin (Detralex) to aid my veins. It's very effective, alleviating pain and swelling in my legs, including my knee pain.
7.5
Improves knee pain
This Vitamin C is beneficial for my veins. My mother has noticed less discomfort around her knee, and we take it each evening.
8
We explored how Vitamin C might affect knee pain in patients suffering from osteoarthritis. The study involved 60 participants who were experiencing clinical and radiological signs of knee osteoarthritis. Over three months, they took Cartinorm, a supplement that included glucosamine sulfate, chondroitin sulfate, forti gel, and Vitamin C, all aimed at improving their symptoms.
While we noticed improvements in movement, reduced pain, and enhanced daily living activities among the patients, it is important to note that we cannot specifically attribute these benefits to Vitamin C alone. It was included in a treatment that involved multiple components, which means isolating its effect on knee pain isn’t feasible with the current data.
Overall, while the treatment showed positive results, the specific impact of Vitamin C on knee pain remains inconclusive. Thus, further studies are necessary to understand its effectiveness in this context.
While we noticed improvements in movement, reduced pain, and enhanced daily living activities among the patients, it is important to note that we cannot specifically attribute these benefits to Vitamin C alone. It was included in a treatment that involved multiple components, which means isolating its effect on knee pain isn’t feasible with the current data.
Overall, while the treatment showed positive results, the specific impact of Vitamin C on knee pain remains inconclusive. Thus, further studies are necessary to understand its effectiveness in this context.
5
Vitamin C's potential in knee recovery
We conducted a study to see how vitamin C, combined with hydrolyzed collagen, could help athletes dealing with knee pain, specifically those suffering from patellar tendinopathy, often known as jumper's knee. Our research involved a double-blind, randomized controlled trial, meaning neither the participants nor the researchers knew who was receiving the real treatment or a placebo. This setup helps ensure that our findings are as accurate as possible.
Over the course of 24 weeks,76 athletes participated in a program that included tendon loading exercises. Those in the intervention group received daily doses of 10 grams of hydrolyzed collagen and 40 milligrams of vitamin C, while the control group took a placebo. We measured their knee pain and overall function using the VISA-P score, a tool designed to assess pain and sports participation effectiveness.
With our detailed approach, we aimed to evaluate whether the combination of vitamin C and collagen showed any significant improvement in knee pain compared to just the exercise program alone. While we continue to analyze our data and await conclusive results, the overall study is pioneering in assessing this unique combination for recovery in athletes experiencing knee pain.
Over the course of 24 weeks,76 athletes participated in a program that included tendon loading exercises. Those in the intervention group received daily doses of 10 grams of hydrolyzed collagen and 40 milligrams of vitamin C, while the control group took a placebo. We measured their knee pain and overall function using the VISA-P score, a tool designed to assess pain and sports participation effectiveness.
With our detailed approach, we aimed to evaluate whether the combination of vitamin C and collagen showed any significant improvement in knee pain compared to just the exercise program alone. While we continue to analyze our data and await conclusive results, the overall study is pioneering in assessing this unique combination for recovery in athletes experiencing knee pain.
9
We designed a prospective randomized study to explore how vitamin C may prevent complex regional pain syndrome (CRPS) in patients recovering from total knee arthroplasty (TKA). This condition often manifests after surgery, causing persistent pain that can severely affect recovery. To evaluate vitamin C's effectiveness, we compared one group of patients receiving vitamin C to another group that did not.
During the research, we included a total of 292 patients, with 153 in the vitamin C group and 139 in the control group. We tracked the incidence of CRPS, applying both the Budapest criteria and bone scintigraphy to make accurate diagnoses.
Our findings revealed a significant difference: only 3.9% of patients in the vitamin C group developed CRPS, compared to 12.2% in the control group. This led us to conclude that taking 1 gram of vitamin C daily for 40 days following TKA can effectively reduce the risk of developing CRPS.
In simple terms, it appears that vitamin C can serve as a valuable preventive measure against chronic pain after knee surgery, providing hope for those aiming to recover smoothly.
During the research, we included a total of 292 patients, with 153 in the vitamin C group and 139 in the control group. We tracked the incidence of CRPS, applying both the Budapest criteria and bone scintigraphy to make accurate diagnoses.
Our findings revealed a significant difference: only 3.9% of patients in the vitamin C group developed CRPS, compared to 12.2% in the control group. This led us to conclude that taking 1 gram of vitamin C daily for 40 days following TKA can effectively reduce the risk of developing CRPS.
In simple terms, it appears that vitamin C can serve as a valuable preventive measure against chronic pain after knee surgery, providing hope for those aiming to recover smoothly.
9
We observed an intriguing case involving a 4.5-year-old boy who developed significant knee pain due to a rare nutritional deficiency, scurvy. This condition stemmed from his exclusive intake of meat over the past two years, resulting in skeletal issues and inflammation in multiple joints, including his knees.
Upon examination, the child exhibited several symptoms, including pain, swelling, and an inability to walk. Standard blood tests primarily indicated anemia, but X-rays revealed alarming conditions related to scurvy, such as delayed bone age and severe osteopenia. This alarming picture led us to the conclusion that vitamin C deficiency was the underlying culprit behind his knee pain and skeletal issues.
After initiating vitamin C therapy, we noted a remarkable reduction in pain and swelling over the next two months. The child’s condition improved significantly, allowing him to walk again, and follow-up X-rays confirmed the positive changes in his bone health. This case clearly illustrates how vitamin C can effectively alleviate knee pain related to scurvy and reinforces the importance of proper nutrition for overall skeletal health.
Upon examination, the child exhibited several symptoms, including pain, swelling, and an inability to walk. Standard blood tests primarily indicated anemia, but X-rays revealed alarming conditions related to scurvy, such as delayed bone age and severe osteopenia. This alarming picture led us to the conclusion that vitamin C deficiency was the underlying culprit behind his knee pain and skeletal issues.
After initiating vitamin C therapy, we noted a remarkable reduction in pain and swelling over the next two months. The child’s condition improved significantly, allowing him to walk again, and follow-up X-rays confirmed the positive changes in his bone health. This case clearly illustrates how vitamin C can effectively alleviate knee pain related to scurvy and reinforces the importance of proper nutrition for overall skeletal health.
References
- Hosseini-Monfared P, Mirahmadi A, Sarzaeem MM, Pourshahryari S, Aminnia P, et al. Ascorbic Acid Reduces the Blood Boss After Total Knee Arthroplasty: Insights From a Randomized Controlled Trial. Arthroplast Today. 2025;32:101618. 10.1016/j.artd.2025.101618
- Muftic M, Trifunovic S, Galijasevic K. Evaluation of the Cartinorm Use in the Therapy of Patients with Knee Osteoarthritis. Mater Sociomed. 2024;36:54. 10.5455/msm.2024.36.54-58
- van Dam L, Terink R, Mensink M, de Vos RJ, Zwerver J. The JUMPFOOD study: additional effect of hydrolyzed collagen and vitamin C to exercise treatment for patellar tendinopathy (jumper's knee) in athletes-study protocol for a double-blind randomized controlled trial. Trials. 2023;24:768. 10.1186/s13063-023-07783-2
- Ramón R, Holguín E, Chiriboga JD, Rubio N, Ballesteros C, et al. Anti-Inflammatory Effect of Vitamin C during the Postoperative Period in Patients Subjected to Total Knee Arthroplasty: A Randomized Controlled Trial. J Pers Med. 2023;13. 10.3390/jpm13091299
- Marquardt P, Raman G, Shen YM, Wang DH. Scurvy: a rare cause of haemarthrosis. BMJ Case Rep. 2022;15. 10.1136/bcr-2021-244594
- Jacques H, Jérôme V, Antoine C, Lucile S, Valérie D, et al. Prospective randomized study of the vitamin C effect on pain and complex pain regional syndrome after total knee arthroplasty. Int Orthop. 2021;45:1155. 10.1007/s00264-020-04936-9
- Kyprios A. Vitamin C Deficiency Presenting as an Acute Limp in Childhood. Cureus. 2020;12:e9182. 10.7759/cureus.9182
- Ripani U, Manzarbeitia-Arroba P, Guijarro-Leo S, Urrutia-Graña J, De Masi-De Luca A. Vitamin C May Help to Reduce the Knee's Arthritic Symptoms. Outcomes Assessment of Nutriceutical Therapy. Med Arch. 2019;73:173. 10.5455/medarh.2019.73.173-177
- López-Vidriero E, Olivé-Vilas R, López-Capapé D, Varela-Sende L, López-Vidriero R, et al. Efficacy and Tolerability of Progen, a Nutritional Supplement Based on Innovative Plasma Proteins, in ACL Reconstruction: A Multicenter Randomized Controlled Trial. Orthop J Sports Med. 2019;7:2325967119827237. 10.1177/2325967119827237
- Gonzalez MJ, Miranda-Massari JR, Berdiel MJ, Duconge J, Rodríguez-López JL, et al. High Dose Intraveneous Vitamin C and Chikungunya Fever: A Case Report. J Orthomol Med. 2014;29:154.
- Noordin S, Baloch N, Salat MS, Rashid Memon A, Ahmad T. Skeletal manifestations of scurvy: a case report from dubai. Case Rep Orthop. 2012;2012:624628. 10.1155/2012/624628
