We explored the effects of vitamin C on natural killer (NK) cell activity in patients with coronary artery disease (CAD). Our research involved isolating NK cells from 29 CAD patients and treating them with various stimulatory factors, including ascorbic acid—better known as vitamin C.
What we found was quite interesting: when NK cells were treated with ascorbic acid, there was a significant increase in their ability to proliferate. This meant that the NK cells were more active and potentially more effective in responding to threats in the body, which is vital for those dealing with heart conditions.
Furthermore, we measured serum lactate dehydrogenase (LDH) levels, discovering a negative correlation between LDH and NK cell activity. Higher LDH levels seemed to indicate lower proliferation capability in NK cells influenced by interleukins.
Overall, our study suggests that vitamin C could play a positive role in enhancing immune function in CAD patients by promoting NK cell proliferation. However, it's important to note that while vitamin C shows promise, further research is needed to fully understand its impact on cardiovascular health and immune regulation.
Read More
8
Vitamin C may help prevent stroke
Causal Effect of Macronutrient and Micronutrient Intake on Stroke: A Two-Sample Mendelian Randomization Study.
We investigated the potential protective effects of vitamin C on stroke risk, drawing on data from a robust two-sample Mendelian randomization study. This research compared genetic predictors of nutrient intake to stroke outcomes, focusing particularly on the intake of various vitamins, including vitamin C.
Our findings revealed that higher levels of vitamin C are linked to a reduced risk of cardioembolic stroke, with a noteworthy odds ratio suggesting that this vitamin could play a significant protective role. Specifically, when we looked at the statistics, the odds ratio was 0.759, indicating a promising association with stroke prevention. This evidence positions vitamin C as a potential target for public health strategies aimed at reducing stroke incidence.
However, while the results regarding vitamin C are encouraging, we must approach them with caution. The overall design of the study limits our conclusions, suggesting that while vitamin C appears beneficial, further research is necessary to fully understand its effects on cardiovascular health.
Read More
9
Vitamin C may lower blood pressure
Effect of vitamin C and hawthorn beverage formula on blood pressure and oxidative stress in heat-exposed workers: a cluster-randomized controlled trial.
We conducted a study to evaluate the effects of a vitamin C supplement combined with a hawthorn beverage on blood pressure and oxidative stress among workers exposed to heat. This involved a 40-day cluster-randomized controlled trial where participants were split into two groups: one received the vitamin C and hawthorn drink, while the other was provided with slightly salted water.
Throughout the study, we measured blood pressure and levels of a specific oxidative stress marker at different intervals. Notably, we observed significant reductions in both systolic and diastolic blood pressure among those who consumed the vitamin C and hawthorn beverage compared to the control group. This suggests that the combination may help manage elevated blood pressure linked to heat exposure.
The findings highlight the potential role of vitamin C, especially when paired with other beneficial compounds in the hawthorn beverage, in combating oxidative stress and promoting cardiovascular health in individuals working in challenging environmental conditions.
Read More
Most Useful Reviews
9
Reduces cold symptoms
2 people found this helpful
I love vitamin C, which is essential for combating cardiovascular disease and boosting immunity. It’s crucial if you experience symptoms like bleeding gums and dry skin. During my recent Covid illness, I doubled the dose and had a mild experience. I recommend keeping it in your medicine cabinet and taking it regularly.
Read More
7.5
Antioxidant benefits
37 people found this helpful
Vitamin C is a powerful antioxidant that aids in relieving cold symptoms, improving skin condition, and promoting wound healing. It also plays a role in reducing the risk of cardiovascular disease.
Read More
9
Prevent viral infections
3 people found this helpful
I take this excellent vitamin for the prevention of viral diseases alongside vitamin D and zinc. Symptoms of deficiency include nosebleeds, bruising, and rough skin. I've noticed joint pain and potential cardiovascular disease complications due to insufficient Vitamin C. This vitamin is suitable for various groups, including smokers and pregnant women. Wishing everyone good health!
Effect of vitamin C and hawthorn beverage formula on blood pressure and oxidative stress in heat-exposed workers: a cluster-randomized controlled trial.
We conducted a study to evaluate the effects of a vitamin C supplement combined with a hawthorn beverage on blood pressure and oxidative stress among workers exposed to heat. This involved a 40-day cluster-randomized controlled trial where participants were split into two groups: one received the vitamin C and hawthorn drink, while the other was provided with slightly salted water.
Throughout the study, we measured blood pressure and levels of a specific oxidative stress marker at different intervals. Notably, we observed significant reductions in both systolic and diastolic blood pressure among those who consumed the vitamin C and hawthorn beverage compared to the control group. This suggests that the combination may help manage elevated blood pressure linked to heat exposure.
The findings highlight the potential role of vitamin C, especially when paired with other beneficial compounds in the hawthorn beverage, in combating oxidative stress and promoting cardiovascular health in individuals working in challenging environmental conditions.
Read More
8
Antioxidants show promise for FGR
The Use of Antioxidants for Cardiovascular Protection in Fetal Growth Restriction: A Systematic Review.
This systematic review focused on the potential effects of antioxidants, particularly vitamin C, on cardiovascular health in cases of fetal growth restriction (FGR). We assessed various studies that examined how these treatments might enhance cardiac and vascular outcomes in affected individuals.
Our exploration revealed that a majority of the studies indicated some level of cardiovascular protection following antioxidant intervention. Specifically, 71% of the studies noted improvements in at least one of the cardiac or vascular parameters in growth-restricted offspring. Vitamin C, along with other antioxidants, was highlighted as part of several approaches to reduce oxidative stress, which is known to contribute to cardiovascular issues.
However, it's essential to note that the specific impact of vitamin C alone was not extensively distinguished from its combined effects with other antioxidants. This ambiguity makes it challenging to pin down its isolated benefits.
Overall, while antioxidant treatments present a promising avenue for addressing cardiovascular deficits associated with FGR, crucial gaps in research remain, preventing us from determining the most effective strategies for clinical use.
Read More
8
Vitamin C may help prevent stroke
Causal Effect of Macronutrient and Micronutrient Intake on Stroke: A Two-Sample Mendelian Randomization Study.
We investigated the potential protective effects of vitamin C on stroke risk, drawing on data from a robust two-sample Mendelian randomization study. This research compared genetic predictors of nutrient intake to stroke outcomes, focusing particularly on the intake of various vitamins, including vitamin C.
Our findings revealed that higher levels of vitamin C are linked to a reduced risk of cardioembolic stroke, with a noteworthy odds ratio suggesting that this vitamin could play a significant protective role. Specifically, when we looked at the statistics, the odds ratio was 0.759, indicating a promising association with stroke prevention. This evidence positions vitamin C as a potential target for public health strategies aimed at reducing stroke incidence.
However, while the results regarding vitamin C are encouraging, we must approach them with caution. The overall design of the study limits our conclusions, suggesting that while vitamin C appears beneficial, further research is necessary to fully understand its effects on cardiovascular health.
Read More
7
Vitamin C enhances NK cell proliferation
Proliferation capability of natural killer cells upon cytokines stimulation correlated negatively with serum lactate dehydrogenase level in coronary artery disease patients.
We explored the effects of vitamin C on natural killer (NK) cell activity in patients with coronary artery disease (CAD). Our research involved isolating NK cells from 29 CAD patients and treating them with various stimulatory factors, including ascorbic acid—better known as vitamin C.
What we found was quite interesting: when NK cells were treated with ascorbic acid, there was a significant increase in their ability to proliferate. This meant that the NK cells were more active and potentially more effective in responding to threats in the body, which is vital for those dealing with heart conditions.
Furthermore, we measured serum lactate dehydrogenase (LDH) levels, discovering a negative correlation between LDH and NK cell activity. Higher LDH levels seemed to indicate lower proliferation capability in NK cells influenced by interleukins.
Overall, our study suggests that vitamin C could play a positive role in enhancing immune function in CAD patients by promoting NK cell proliferation. However, it's important to note that while vitamin C shows promise, further research is needed to fully understand its impact on cardiovascular health and immune regulation.
Read More
User Reviews
USERS' SCORE
Good
Based on 4 Reviews
8.3
All Reviews
Positive Reviews
Negative Reviews
9
Reduces cold symptoms
2 people found this helpful
I love vitamin C, which is essential for combating cardiovascular disease and boosting immunity. It’s crucial if you experience symptoms like bleeding gums and dry skin. During my recent Covid illness, I doubled the dose and had a mild experience. I recommend keeping it in your medicine cabinet and taking it regularly.
Read More
7.5
Antioxidant benefits
37 people found this helpful
Vitamin C is a powerful antioxidant that aids in relieving cold symptoms, improving skin condition, and promoting wound healing. It also plays a role in reducing the risk of cardiovascular disease.
Read More
9
Prevent viral infections
3 people found this helpful
I take this excellent vitamin for the prevention of viral diseases alongside vitamin D and zinc. Symptoms of deficiency include nosebleeds, bruising, and rough skin. I've noticed joint pain and potential cardiovascular disease complications due to insufficient Vitamin C. This vitamin is suitable for various groups, including smokers and pregnant women. Wishing everyone good health!
Read More
7.5
Supports cardiovascular health
After Covid, my doctor prescribed this to support my cardiovascular system. It’s a quality product, and the size is comfortable to take.
Read More
Frequently Asked Questions
Cardiovascular disease (CVD) is a broad term that encompasses a range of heart and blood vessel disorders. This can include conditions such as coronary artery disease, which leads to heart attacks; cerebrovascular disease that results in strokes; and peripheral artery disease affecting blood flow to the limbs. The key risk factors for CVD often include high blood pressure, high cholesterol, obesity, smoking, a sedentary lifestyle, and diabetes. By identifying and managing these risk factors, individuals can significantly reduce their likelihood of developing cardiovascular problems.
Prevention and treatment strategies often involve lifestyle modifications such as adopting a heart-healthy diet rich in fruits, vegetables, whole grains, and lean proteins, alongside engaging in regular physical activity. In some cases, medications might be necessary to control blood pressure or cholesterol levels. Regular check-ups with a healthcare provider are essential for monitoring heart health, especially for individuals with a family history of CVD. Understanding the signs and symptoms of cardiovascular issues—like chest pain, shortness of breath, or fatigue—can help in seeking timely medical attention, ultimately leading to better outcomes.
Vitamin C, also known as ascorbic acid, is a water-soluble vitamin that plays a critical role in numerous bodily functions. As an essential nutrient, it contributes to the growth and repair of tissues in the body, and it is vital for the production of collagen, an important protein that helps maintain skin, cartilage, tendons, ligaments, and blood vessels. Additionally, Vitamin C acts as a powerful antioxidant, which means it helps combat free radicals—unstable molecules that can cause oxidative stress and contribute to various chronic diseases.
Moreover, Vitamin C enhances iron absorption from plant-based foods, making it a vital component for those following vegetarian or vegan diets. While many people get sufficient Vitamin C from a well-balanced diet that includes fruits and vegetables like oranges, strawberries, kiwi, broccoli, and bell peppers, some individuals might require supplementation. It's generally recommended to stay within the daily intake guidelines, as excessive consumption can lead to gastrointestinal disturbances. Overall, Vitamin C is not just a skincare celebrity—it's a fundamental part of maintaining overall health and well-being.
While there is ongoing research into the effects of Vitamin C on cardiovascular health, the evidence remains mixed. Some studies suggest that Vitamin C may help improve endothelial function, lower blood pressure, and reduce oxidized LDL cholesterol, which are all risk factors associated with cardiovascular disease. Antioxidants like Vitamin C can combat oxidative stress, a contributor to various health issues, including heart disease. However, it's essential to note that these potential benefits are often seen when Vitamin C is consumed as part of a balanced diet rich in fruits and vegetables, rather than in supplement form alone.
On the flip side, there are also studies that show no significant long-term benefits of Vitamin C supplementation in preventing heart disease or improving heart health outcomes. The American Heart Association emphasizes that focusing on overall dietary patterns and lifestyle changes—like increased physical activity, maintaining a healthy weight, and a diet high in whole foods—should be prioritized over relying solely on individual supplements. Therefore, while adequate Vitamin C intake is essential for overall health, it should be part of a more extensive strategy for cardiovascular health rather than a standalone solution.
Based on user reviews, the timeline for experiencing results from taking vitamin C as a supplement for cardiovascular disease varies. Several users noted the importance of regular intake and suggested seeing improvements over time. For example, one user mentioned that vitamin C aids in preventing complications associated with cardiovascular disease, although they didn't specify a timeframe for results Read Review. Another user, who took vitamin C after recovering from Covid, emphasized its role in supporting cardiovascular health, indicating that consistent use is key, but again, did not provide a specific duration to see noticeable results Read Review.
While specific timelines were scarce, many users recommend maintaining regular dosages to achieve optimum benefits. In essence, those looking to enhance their cardiovascular health with vitamin C should expect to adhere to a routine before seeing marked improvements, with anecdotal evidence pointing towards extended use as beneficial. Consistency seems to be a common theme for users aiming for cardiovascular support Read Review.
Vitamin C has shown promising potential in supporting cardiovascular health based on several studies. One systematic review highlighted the effects of antioxidants, including vitamin C, in enhancing cardiac and vascular outcomes in individuals affected by fetal growth restriction. Notably, 71% of studies within this review reported improvements in cardiac or vascular parameters following antioxidant treatments, suggesting vitamin C could play a role in reducing oxidative stress related to cardiovascular issues [1].
Furthermore, a study focused on patients with coronary artery disease found that vitamin C significantly boosted the activity of natural killer (NK) cells, which are crucial for immune response in heart disease patients. This suggests that vitamin C may enhance immune function and potentially mitigate some cardiovascular risks [2]. Additional findings indicate that higher vitamin C levels are linked to a reduced risk of cardioembolic strokes, highlighting its significance in stroke prevention [3]. Finally, a trial involving heat-exposed workers revealed that a combination of vitamin C and hawthorn reduced blood pressure, further supporting its cardiovascular benefits [4]. Overall, the existing evidence points towards vitamin C being a promising supplement for cardiovascular health, although more research is needed to fully understand its mechanisms and effects.
Based on user reviews, many individuals have reported positive improvements in symptoms relating to cardiovascular health and overall wellness after incorporating vitamin C into their routines. For instance, one user highlighted the vitamin's essential role in preventing symptoms such as bleeding gums and dry skin, emphasizing its importance during their recent recovery from Covid, which involved doubling the dose for increased support Read Review. Another user noted that vitamin C not only aids in battling cold symptoms but also plays a significant role in enhancing skin health and promoting wound healing, which correlates with improved overall health Read Review.
Several users also pointed out the supplement's preventive qualities against viral diseases and potential complications, particularly for those at risk. One reviewer shared their experience of noticing joint pain and cardiovascular complications that they attributed to vitamin C deficiency, highlighting its critical role in maintaining health Read Review. Another user emphasized the importance of supplementation post-Covid, noting the support it provides for the cardiovascular system, yet specific timelines for significant improvements were not clearly defined in the reviews Read Review. Overall, users recommend regular intake to maximize the benefits, although individual results may vary.
According to user reviews, many individuals have successfully combined vitamin C with other supplements, particularly vitamin D and zinc, to enhance their cardiovascular health. One user shared their experience of taking vitamin C along with these supplements for the prevention of viral diseases, stating that they noticed symptoms of deficiency such as bruising and joint pain related to cardiovascular complications Read Review. This user emphasized the supplement’s preventive qualities, indicating that a balanced combination can be beneficial for overall wellness.
Another reviewer highlighted that their doctor specifically recommended vitamin C post-Covid to support cardiovascular health Read Review. Users seem to agree that maintaining a routine that includes vitamin C—preferably in conjunction with other supportive supplements—can optimize cardiovascular health outcomes, particularly when addressing symptoms or complications arising from deficiency. Regular intake is a recurring theme, underlining the importance of adherence to supplementation for achieving the best results Read Review.
Based on user reviews, many individuals report that Vitamin C plays a significant role in combating cardiovascular disease and other health issues. One user specifically mentioned increasing their Vitamin C intake during illness, finding it beneficial, particularly for symptoms like bleeding gums and dry skin Read Review. Another user highlighted that Vitamin C is essential for reducing the risk of cardiovascular disease and for overall immune support Read Review.
In terms of dosage, while specific quantities weren't explicitly detailed, users seem to advocate for regular intake, varying the amount based on individual circumstances, such as increased need during illness. One reviewer indicated that they doubled their dose during a health crisis, suggesting that personal needs can dictate dosage adjustments Read Review. Another pointed out that their doctor prescribed Vitamin C post-Covid to support cardiovascular health, implying that professional guidance can be crucial in determining the right dosage Read Review.
9
Prevent viral infections
3 people found this helpful
I take this excellent vitamin for the prevention of viral diseases alongside vitamin D and zinc. Symptoms of deficiency include nosebleeds, bruising, and rough skin. I've noticed joint pain and potential cardiovascular disease complications due to insufficient Vitamin C. This vitamin is suitable for various groups, including smokers and pregnant women. Wishing everyone good health!
7.5
Supports cardiovascular health
After Covid, my doctor prescribed this to support my cardiovascular system. It’s a quality product, and the size is comfortable to take.
7.5
Antioxidant benefits
37 people found this helpful
Vitamin C is a powerful antioxidant that aids in relieving cold symptoms, improving skin condition, and promoting wound healing. It also plays a role in reducing the risk of cardiovascular disease.
9
Reduces cold symptoms
2 people found this helpful
I love vitamin C, which is essential for combating cardiovascular disease and boosting immunity. It’s crucial if you experience symptoms like bleeding gums and dry skin. During my recent Covid illness, I doubled the dose and had a mild experience. I recommend keeping it in your medicine cabinet and taking it regularly.
8
Antioxidants show promise for FGR
The Use of Antioxidants for Cardiovascular Protection in Fetal Growth Restriction: A Systematic Review.
This systematic review focused on the potential effects of antioxidants, particularly vitamin C, on cardiovascular health in cases of fetal growth restriction (FGR). We assessed various studies that examined how these treatments might enhance cardiac and vascular outcomes in affected individuals.
Our exploration revealed that a majority of the studies indicated some level of cardiovascular protection following antioxidant intervention. Specifically, 71% of the studies noted improvements in at least one of the cardiac or vascular parameters in growth-restricted offspring. Vitamin C, along with other antioxidants, was highlighted as part of several approaches to reduce oxidative stress, which is known to contribute to cardiovascular issues.
However, it's essential to note that the specific impact of vitamin C alone was not extensively distinguished from its combined effects with other antioxidants. This ambiguity makes it challenging to pin down its isolated benefits.
Overall, while antioxidant treatments present a promising avenue for addressing cardiovascular deficits associated with FGR, crucial gaps in research remain, preventing us from determining the most effective strategies for clinical use.
7
Vitamin C enhances NK cell proliferation
Proliferation capability of natural killer cells upon cytokines stimulation correlated negatively with serum lactate dehydrogenase level in coronary artery disease patients.
We explored the effects of vitamin C on natural killer (NK) cell activity in patients with coronary artery disease (CAD). Our research involved isolating NK cells from 29 CAD patients and treating them with various stimulatory factors, including ascorbic acid—better known as vitamin C.
What we found was quite interesting: when NK cells were treated with ascorbic acid, there was a significant increase in their ability to proliferate. This meant that the NK cells were more active and potentially more effective in responding to threats in the body, which is vital for those dealing with heart conditions.
Furthermore, we measured serum lactate dehydrogenase (LDH) levels, discovering a negative correlation between LDH and NK cell activity. Higher LDH levels seemed to indicate lower proliferation capability in NK cells influenced by interleukins.
Overall, our study suggests that vitamin C could play a positive role in enhancing immune function in CAD patients by promoting NK cell proliferation. However, it's important to note that while vitamin C shows promise, further research is needed to fully understand its impact on cardiovascular health and immune regulation.
8
Vitamin C may help prevent stroke
Causal Effect of Macronutrient and Micronutrient Intake on Stroke: A Two-Sample Mendelian Randomization Study.
We investigated the potential protective effects of vitamin C on stroke risk, drawing on data from a robust two-sample Mendelian randomization study. This research compared genetic predictors of nutrient intake to stroke outcomes, focusing particularly on the intake of various vitamins, including vitamin C.
Our findings revealed that higher levels of vitamin C are linked to a reduced risk of cardioembolic stroke, with a noteworthy odds ratio suggesting that this vitamin could play a significant protective role. Specifically, when we looked at the statistics, the odds ratio was 0.759, indicating a promising association with stroke prevention. This evidence positions vitamin C as a potential target for public health strategies aimed at reducing stroke incidence.
However, while the results regarding vitamin C are encouraging, we must approach them with caution. The overall design of the study limits our conclusions, suggesting that while vitamin C appears beneficial, further research is necessary to fully understand its effects on cardiovascular health.
9
Vitamin C may lower blood pressure
Effect of vitamin C and hawthorn beverage formula on blood pressure and oxidative stress in heat-exposed workers: a cluster-randomized controlled trial.
We conducted a study to evaluate the effects of a vitamin C supplement combined with a hawthorn beverage on blood pressure and oxidative stress among workers exposed to heat. This involved a 40-day cluster-randomized controlled trial where participants were split into two groups: one received the vitamin C and hawthorn drink, while the other was provided with slightly salted water.
Throughout the study, we measured blood pressure and levels of a specific oxidative stress marker at different intervals. Notably, we observed significant reductions in both systolic and diastolic blood pressure among those who consumed the vitamin C and hawthorn beverage compared to the control group. This suggests that the combination may help manage elevated blood pressure linked to heat exposure.
The findings highlight the potential role of vitamin C, especially when paired with other beneficial compounds in the hawthorn beverage, in combating oxidative stress and promoting cardiovascular health in individuals working in challenging environmental conditions.
References
Rock CR, Miller SL, Allison BJ. The Use of Antioxidants for Cardiovascular Protection in Fetal Growth Restriction: A Systematic Review. Antioxidants (Basel). 2024;13. 10.3390/antiox13111400
Guo X, Xiao T, Lin L, Gao Q, Lai B, et al. Proliferation capability of natural killer cells upon cytokines stimulation correlated negatively with serum lactate dehydrogenase level in coronary artery disease patients. Front Immunol. 2024;15:1436747. 10.3389/fimmu.2024.1436747
Dong G, Xu W, Xu L. Causal Effect of Macronutrient and Micronutrient Intake on Stroke: A Two-Sample Mendelian Randomization Study. Nutrients. 2024;16. 10.3390/nu16172818
Du W, Zhang S, Yang J, Fan H. Effect of vitamin C and hawthorn beverage formula on blood pressure and oxidative stress in heat-exposed workers: a cluster-randomized controlled trial. Asia Pac J Clin Nutr. 2024;33:503. 10.6133/apjcn.202412_33(4).0005