Reviewed By
Reviewed By
Overview
![Solgar Solgar B-Complex "100"](https://m.media-amazon.com/images/I/41OvoQlDt2L._SL500_.jpg "Solgar Solgar B-Complex "100"")
SCIENTIFIC SCORE
Moderately Effective
Based on 5 Researches
8
USERS' SCORE
Good
Based on 12 Reviews
8.2
Supplement Facts
Serving Size: 1 Vegetable capsule
Amount Per Serving
%DV
Thiamin (vitamin B1) (as thiamin mononitrate)
100 mg
8,333%
Riboflavin (vitamin B2)
100 mg
7,692%
Niacin (vitamin B3) (as niacinamide)
100 mg
625%
Vitamin B6 (as pyridoxine HCl)
100 mg
5,882%
Folate
666 mcg DFE(400 mcg folic acid)
167%
Vitamin B12 (as cyanocobalamin)
100 mcg
4,167%
Biotin (as d-biotin)
100 mcg
333%
Pantothenic Acid (vitamin B5) (as d-calcium pantothenate)
100 mg
2,000%
Choline (as choline bitartrate)
20 mg
4%
Inositol
100 mg
**
Top Medical Research Studies
8
We focused on a case of pernicious anemia in a 51-year-old Ugandan man who presented with recurring lower limb weakness. After initial treatment for vitamin B12 deficiency years ago and further testing, we confirmed his diagnosis of pernicious anemia marked by low cobalamin levels. Thanks to timely parenteral methylcobalamin therapy, he showed improvement. This case underscores the importance of recognizing vitamin B12 deficiency, especially in rural and resource-limited settings, to address neurological symptoms quickly.
Read More
8
Pernicious anemia misdiagnosed as fibromyalgia
We explored a notable case of a woman suffering from pernicious anemia, an autoimmune condition that can be misdiagnosed due to its vague symptoms like fatigue and cognitive issues.
After years of struggling with these nonspecific symptoms, her low vitamin B12 levels were finally identified as the underlying cause.
Upon receiving treatment with vitamin B12, she experienced neurological improvements, highlighting the importance of recognizing this deficiency, even when traditional anemia indicators are absent.
After years of struggling with these nonspecific symptoms, her low vitamin B12 levels were finally identified as the underlying cause.
Upon receiving treatment with vitamin B12, she experienced neurological improvements, highlighting the importance of recognizing this deficiency, even when traditional anemia indicators are absent.
Read More
8
We explored the influence of Nicotinamide (NAM), a form of vitamin B3, on dendritic cells (DCs) in autoimmune diseases. Our research indicates that NAM can effectively reduce the overactivation of DCs, helping to ease symptoms in conditions like psoriasis.
Through detailed analysis of available studies, we found that NAM affects DCs via a specific signaling pathway, ultimately offering a potential new direction for treatment. Importantly, these findings highlight NAM’s significant role in managing autoimmune disorders related to immune response regulation.
Through detailed analysis of available studies, we found that NAM affects DCs via a specific signaling pathway, ultimately offering a potential new direction for treatment. Importantly, these findings highlight NAM’s significant role in managing autoimmune disorders related to immune response regulation.
Read More
Most Useful Reviews
9
Decreased psoriasis rashes
5 people found this helpful
We are delighted with this complex. My husband suffers from psoriasis, which flares up during autumn and spring. After consulting a dermatologist, we introduced B vitamins and decided to try this product. It helped reduce rashes, particularly those on his face. We will continue to order this.
Read More
9
Nervous system improvement
4 people found this helpful
I’ve ordered this vitamin for the third time. I’ve tried various B compounds, but this one stands out for its effectiveness on my nervous system. From the second capsule, I noticed improvement. The rich ingredients last over three months, making it safe for long-term use, although it's best taken in the morning to avoid insomnia.
Read More
9
Pain relief noted
2 people found this helpful
I order this B complex for the third time. It is beneficial for back pain, tension, and increasing my endurance and concentration. Initially, the high dosage worried me, but I recognised the necessity for such treatment. I take it in cycles during spring and autumn for about 1-1.5 months.
Read More
Medical Researches
SCIENTIFIC SCORE
Moderately Effective
Based on 5 Researches
8
- All Researches
9
Biotin deficiency mimics neurological disorders
We explored three cases of biotinidase deficiency (BTD) that were misdiagnosed as neuromyelitis optica spectrum disorder (NMOSD) due to similar symptoms and neuroimaging results. Initially, two patients responded to immune therapy but later relapsed, while one showed no improvement. Interestingly, after timely diagnosis and biotin supplementation, two patients exhibited remarkable recoveries in both motor function and vision. This highlights the critical need for accurate diagnosis, as early treatment of BTD can lead to significant improvements.
Read More
8
Pernicious anemia misdiagnosed as fibromyalgia
We explored a notable case of a woman suffering from pernicious anemia, an autoimmune condition that can be misdiagnosed due to its vague symptoms like fatigue and cognitive issues.
After years of struggling with these nonspecific symptoms, her low vitamin B12 levels were finally identified as the underlying cause.
Upon receiving treatment with vitamin B12, she experienced neurological improvements, highlighting the importance of recognizing this deficiency, even when traditional anemia indicators are absent.
After years of struggling with these nonspecific symptoms, her low vitamin B12 levels were finally identified as the underlying cause.
Upon receiving treatment with vitamin B12, she experienced neurological improvements, highlighting the importance of recognizing this deficiency, even when traditional anemia indicators are absent.
Read More
8
We focused on a case of pernicious anemia in a 51-year-old Ugandan man who presented with recurring lower limb weakness. After initial treatment for vitamin B12 deficiency years ago and further testing, we confirmed his diagnosis of pernicious anemia marked by low cobalamin levels. Thanks to timely parenteral methylcobalamin therapy, he showed improvement. This case underscores the importance of recognizing vitamin B12 deficiency, especially in rural and resource-limited settings, to address neurological symptoms quickly.
Read More
8
We explored the influence of Nicotinamide (NAM), a form of vitamin B3, on dendritic cells (DCs) in autoimmune diseases. Our research indicates that NAM can effectively reduce the overactivation of DCs, helping to ease symptoms in conditions like psoriasis.
Through detailed analysis of available studies, we found that NAM affects DCs via a specific signaling pathway, ultimately offering a potential new direction for treatment. Importantly, these findings highlight NAM’s significant role in managing autoimmune disorders related to immune response regulation.
Through detailed analysis of available studies, we found that NAM affects DCs via a specific signaling pathway, ultimately offering a potential new direction for treatment. Importantly, these findings highlight NAM’s significant role in managing autoimmune disorders related to immune response regulation.
Read More
7
Vitamin B may indicate GBS severity
We aimed to see if vitamin B levels could signal the severity of Guillain-Barré syndrome (GBS) and its potential for complications like respiratory failure. Our study involved 50 GBS patients, where we examined their vitamin B and creatine kinase levels alongside their motor abilities.
Interestingly, we found that 44% of patients had low vitamin B levels, which linked strongly to GBS severity. However, while vitamin B showed predictive value, the creatine kinase levels did not relate to GBS severity.
Interestingly, we found that 44% of patients had low vitamin B levels, which linked strongly to GBS severity. However, while vitamin B showed predictive value, the creatine kinase levels did not relate to GBS severity.
Read More
User Reviews
USERS' SCORE
Good
Based on 12 Reviews
8.2
- All Reviews
- Positive Reviews
- Negative Reviews
9
Decreased psoriasis rashes
5 people found this helpful
We are delighted with this complex. My husband suffers from psoriasis, which flares up during autumn and spring. After consulting a dermatologist, we introduced B vitamins and decided to try this product. It helped reduce rashes, particularly those on his face. We will continue to order this.
Read More
9
Nervous system improvement
4 people found this helpful
I’ve ordered this vitamin for the third time. I’ve tried various B compounds, but this one stands out for its effectiveness on my nervous system. From the second capsule, I noticed improvement. The rich ingredients last over three months, making it safe for long-term use, although it's best taken in the morning to avoid insomnia.
Read More
9
Pain relief noted
2 people found this helpful
I order this B complex for the third time. It is beneficial for back pain, tension, and increasing my endurance and concentration. Initially, the high dosage worried me, but I recognised the necessity for such treatment. I take it in cycles during spring and autumn for about 1-1.5 months.
Read More
9
Effective treatment
These vitamins are recommended by my endocrinologist, who advised me to get this particular brand from iHerb. I initially had issues with depression and chronic fatigue syndrome, but after taking these vitamins alongside vitamin D, I feel fantastic! I have the energy to handle my household tasks and care for my children throughout the day.
Read More
7.5
Reduced panic attacks
136 people found this helpful
Excellent vitamins. No injections needed. After using Berocca, which was expensive and ineffective, I experienced anxiety and eye twitching. After a week on these vitamins, my symptoms disappeared. They also helped alleviate panic attacks and discomfort from my autoimmune disorder related to osteochondrosis. Taken with chelated magnesium, my breathing issues resolved. If you found this helpful, please like it :)
Read More
Frequently Asked Questions
7.5
Reduced panic attacks
136 people found this helpful
Excellent vitamins. No injections needed. After using Berocca, which was expensive and ineffective, I experienced anxiety and eye twitching. After a week on these vitamins, my symptoms disappeared. They also helped alleviate panic attacks and discomfort from my autoimmune disorder related to osteochondrosis. Taken with chelated magnesium, my breathing issues resolved. If you found this helpful, please like it :)
7.5
Increased energy levels
4 people found this helpful
For a long time, I suffered from lethargy and muscle pain, not understanding the cause. After researching, I discovered I had a lack of B vitamins. I ordered Solgar B vitamins, which are high quality and contain all B vitamins. A week later, I felt energised and less irritable, and my autoimmune disorder symptoms improved.
9
Pain relief noted
2 people found this helpful
I order this B complex for the third time. It is beneficial for back pain, tension, and increasing my endurance and concentration. Initially, the high dosage worried me, but I recognised the necessity for such treatment. I take it in cycles during spring and autumn for about 1-1.5 months.
9
Decreased psoriasis rashes
5 people found this helpful
We are delighted with this complex. My husband suffers from psoriasis, which flares up during autumn and spring. After consulting a dermatologist, we introduced B vitamins and decided to try this product. It helped reduce rashes, particularly those on his face. We will continue to order this.
9
Nervous system improvement
4 people found this helpful
I’ve ordered this vitamin for the third time. I’ve tried various B compounds, but this one stands out for its effectiveness on my nervous system. From the second capsule, I noticed improvement. The rich ingredients last over three months, making it safe for long-term use, although it's best taken in the morning to avoid insomnia.
9
Effective treatment
These vitamins are recommended by my endocrinologist, who advised me to get this particular brand from iHerb. I initially had issues with depression and chronic fatigue syndrome, but after taking these vitamins alongside vitamin D, I feel fantastic! I have the energy to handle my household tasks and care for my children throughout the day.
6
Vitamins improved health
41 people found this helpful
I ordered these vitamins Realising my body was exhausted. I experienced lethargy and irritability, knowing I lacked B vitamins. I took a higher dosage and felt significantly better on gloomy days, but reduced my intake when I felt good. My test results showed elevated B12 levels, indicating the necessity for a break. These vitamins work!
8
Pernicious anemia misdiagnosed as fibromyalgia
We explored a notable case of a woman suffering from pernicious anemia, an autoimmune condition that can be misdiagnosed due to its vague symptoms like fatigue and cognitive issues.
After years of struggling with these nonspecific symptoms, her low vitamin B12 levels were finally identified as the underlying cause.
Upon receiving treatment with vitamin B12, she experienced neurological improvements, highlighting the importance of recognizing this deficiency, even when traditional anemia indicators are absent.
After years of struggling with these nonspecific symptoms, her low vitamin B12 levels were finally identified as the underlying cause.
Upon receiving treatment with vitamin B12, she experienced neurological improvements, highlighting the importance of recognizing this deficiency, even when traditional anemia indicators are absent.
8
We focused on a case of pernicious anemia in a 51-year-old Ugandan man who presented with recurring lower limb weakness. After initial treatment for vitamin B12 deficiency years ago and further testing, we confirmed his diagnosis of pernicious anemia marked by low cobalamin levels. Thanks to timely parenteral methylcobalamin therapy, he showed improvement. This case underscores the importance of recognizing vitamin B12 deficiency, especially in rural and resource-limited settings, to address neurological symptoms quickly.
8
We explored the influence of Nicotinamide (NAM), a form of vitamin B3, on dendritic cells (DCs) in autoimmune diseases. Our research indicates that NAM can effectively reduce the overactivation of DCs, helping to ease symptoms in conditions like psoriasis.
Through detailed analysis of available studies, we found that NAM affects DCs via a specific signaling pathway, ultimately offering a potential new direction for treatment. Importantly, these findings highlight NAM’s significant role in managing autoimmune disorders related to immune response regulation.
Through detailed analysis of available studies, we found that NAM affects DCs via a specific signaling pathway, ultimately offering a potential new direction for treatment. Importantly, these findings highlight NAM’s significant role in managing autoimmune disorders related to immune response regulation.
References
- Jatav VS, Sardana V, Bhushan B, Maheshwari D, Garg S, et al. Correlation of Serum Vitamin B and Muscle Enzyme (CK-NAC) Level with Severity of Guillain-Barre Syndrome and Its Prediction in Respiratory Failure. J Assoc Physicians India. 2025;73:48. 10.59556/japi.73.0892
- Mesgarankarimi A, Rezapour M, Tabrizi N. A long-standing undiagnosed case of vitamin B12 deficiency: a case report. J Med Case Rep. 2025;19:151. 10.1186/s13256-025-05149-7
- Mswelo VE, David MM, Banturaki A, Munyambalu DK, Hassan HA, et al. Rural health challenges in Western Uganda: pernicious anemia masquerading as recurrent lower limb weakness-a case report. J Med Case Rep. 2025;19:60. 10.1186/s13256-025-05095-4
- Cao AP, Wang YY, Shen YY, Liu YH, Liu JY, et al. Nicotinamide Suppresses Hyperactivation of Dendritic Cells to Control Autoimmune Disease through PARP Dependent Signaling. Nutrients. 2024;16. 10.3390/nu16162665
- Ali F, Mukhtiar K, Raza M, Ibrahim S. Atypical presentation of biotinidase deficiency: masquerading neuromyelitis optica spectrum disorder. BMJ Case Rep. 2024;17. 10.1136/bcr-2023-258703
