Overview

SCIENTIFIC SCORE
Moderately Effective
Based on 7 Researches
8.6
USERS' SCORE
Good
Based on 11 Reviews
8.4
Supplement Facts
Serving Size: 1 Vegetable capsule
Amount Per Serving
%DV
Thiamin (vitamin B1) (as thiamin mononitrate)
100 mg
8,333%
Riboflavin (vitamin B2)
100 mg
7,692%
Niacin (vitamin B3) (as niacinamide)
100 mg
625%
Vitamin B6 (as pyridoxine HCl)
100 mg
5,882%
Folate
666 mcg DFE(400 mcg folic acid)
167%
Vitamin B12 (as cyanocobalamin)
100 mcg
4,167%
Biotin (as d-biotin)
100 mcg
333%
Pantothenic Acid (vitamin B5) (as d-calcium pantothenate)
100 mg
2,000%
Choline (as choline bitartrate)
20 mg
4%
Inositol
100 mg
**

Top Medical Research Studies

We investigated how benfotiamine might impact stomach ulcers in male rats. The study involved dividing 30 rats into groups receiving different treatments, including benfotiamine at varying doses, following the induction of ulcers using indomethacin.

Our results showed that benfotiamine notably decreased gastric damage and lowered inflammation markers. Specifically, doses of 100 and 200 mg/kg appeared to enhance antioxidant levels and reduce tissue damage.

However, while these findings are promising, more research is needed to fully understand the mechanisms at play and assess benfotiamine's potential for human treatment.
Read More
8
ImproWin® aids gastric ulcer healing
We aimed to determine if ImproWin®, a feed additive, could help improve gastric ulcers in Standardbred and Coldblooded trotting racehorses. By conducting a randomized, double-blinded study, we assessed horses' ulcers before and after three weeks of treatment.

Our results showed a significant reduction in ulcer scores for horses treated with ImproWin®, with 78% classified as responders compared to only 54.8% in the placebo group. This indicates that ImproWin® may be beneficial for aiding the healing of gastric ulcers in affected racehorses.
Read More
8
Folic acid has mixed effects
We examined how different doses of folic acid supplementation affect ulcer formation in rats. Male Wistar rats were treated with varying doses for 21 days while gastric ulcers were induced with indomethacin.

We found that a dose of 2 mg/kg significantly reduced gastric lesions, while a higher dose of 3 mg/kg unexpectedly worsened damage. Our results suggest that low doses of folic acid can be protective for the stomach, but high doses could pose risks.

Thus, it appears that moderation is key when considering folic acid for ulcer treatment.
Read More

Most Useful Reviews

9
Effectively treats ulcer
3 people found this helpful
Those suffering from stomach ulcers, mouth ulcers, and daily fatigue should consider this product. I was sceptical initially, but after using the socio-vitamin-non-complex along with Ginga Minggae's herbal supplements, it significantly improved my husband's mouth ulcers. The B vitamins here are especially effective; I highly recommend this, but be cautious as the pills are quite large!
Read More
9
Reduces oral ulcers
1 people found this helpful
Human metabolism requires the B vitamins. After taking them for a while, I no longer experience oral ulcers. The effect is impressive, and I plan to keep taking them.
Read More
9
No more ulcers
1 people found this helpful
I feel great! I've tried various supplements to prevent mouth ulcers with little success. Unexpectedly, I haven't had any since using this product, likely due to its abundant B vitamins. My trust in "Solgar" has definitely grown.
Read More

Medical Researches

SCIENTIFIC SCORE
Moderately Effective
Based on 7 Researches
8.6
  • All Researches
We analyzed the potential connection between folic acid supplementation and gastric ulcers using data from the UK Biobank and advanced statistical methods.

Our findings suggest that folic acid may significantly lower the risk of developing gastric ulcers.

Various robust models reinforced this result, showing consistent outcomes across different analyses.

Ultimately, this research provides genetic evidence supporting the idea that receiving folic acid therapy can be beneficial in reducing gastric ulcer risk.
Read More
We investigated how benfotiamine might impact stomach ulcers in male rats. The study involved dividing 30 rats into groups receiving different treatments, including benfotiamine at varying doses, following the induction of ulcers using indomethacin.

Our results showed that benfotiamine notably decreased gastric damage and lowered inflammation markers. Specifically, doses of 100 and 200 mg/kg appeared to enhance antioxidant levels and reduce tissue damage.

However, while these findings are promising, more research is needed to fully understand the mechanisms at play and assess benfotiamine's potential for human treatment.
Read More
9
Effective ulcer treatment in diabetes
We explored the effects of Luffa acutangula extracts on gastric ulcers in diabetic rats. By inducing non-insulin dependent diabetes mellitus (NIDDM) and then creating gastric ulcers, we evaluated the extracts' potential for healing.

The results showed that the methanolic extract significantly boosted healing, improving protective mucosal glycoproteins and antioxidant levels. This was better than the aqueous extract and standard treatments.

Overall, Luffa acutangula appears to offer promising support for treating gastric ulcers in diabetes, highlighting its dual action in managing both conditions.
Read More
9
Effective treatment for oral ulcers
We explored the effectiveness of mecobalamin and vitamin E in treating recurrent oral ulcers. In a study with 58 patients, those receiving both treatments showed significantly improved healing times and reduced symptoms compared to the control group. They experienced longer periods without ulcer flare-ups and better quality of life scores. Both groups felt pain relief, but the test group had more noticeable benefits. This finding suggests that mecobalamin and vitamin E can be a valuable addition to ulcer treatment, enhancing both comfort and recovery.
Read More
8
ImproWin® aids gastric ulcer healing
We aimed to determine if ImproWin®, a feed additive, could help improve gastric ulcers in Standardbred and Coldblooded trotting racehorses. By conducting a randomized, double-blinded study, we assessed horses' ulcers before and after three weeks of treatment.

Our results showed a significant reduction in ulcer scores for horses treated with ImproWin®, with 78% classified as responders compared to only 54.8% in the placebo group. This indicates that ImproWin® may be beneficial for aiding the healing of gastric ulcers in affected racehorses.
Read More

User Reviews

USERS' SCORE
Good
Based on 11 Reviews
8.4
  • All Reviews
  • Positive Reviews
  • Negative Reviews
9
Effectively treats ulcer
3 people found this helpful
Those suffering from stomach ulcers, mouth ulcers, and daily fatigue should consider this product. I was sceptical initially, but after using the socio-vitamin-non-complex along with Ginga Minggae's herbal supplements, it significantly improved my husband's mouth ulcers. The B vitamins here are especially effective; I highly recommend this, but be cautious as the pills are quite large!
Read More
9
Reduces oral ulcers
1 people found this helpful
Human metabolism requires the B vitamins. After taking them for a while, I no longer experience oral ulcers. The effect is impressive, and I plan to keep taking them.
Read More
9
No more ulcers
1 people found this helpful
I feel great! I've tried various supplements to prevent mouth ulcers with little success. Unexpectedly, I haven't had any since using this product, likely due to its abundant B vitamins. My trust in "Solgar" has definitely grown.
Read More
9
Less frequent ulcers
Vitamin B helps reduce mouth ulcers! I tended to get them easily and often felt fatigued. Since starting this, I'm getting fewer ulcers and have come to realise the importance of vitamin B. The ingredients are excellent!
Read More
9
Immediate effect
This B complex product delivered immediate results. I frequently suffered from mouth ulcers. The high-quality ingredients made a noticeable difference. I consider it essential to my supplements.
Read More

Frequently Asked Questions

7.5
Soothes ulcer pain
This product helped soothe my mouth ulcer pain after just two doses, especially when combined with “immune 4”.
9
Immediate effect
This B complex product delivered immediate results. I frequently suffered from mouth ulcers. The high-quality ingredients made a noticeable difference. I consider it essential to my supplements.
9
Effective prevention
I find this product beneficial. I previously took Solgar B Complex 50 for my frequent stomatitis, but this seems more effective, reducing the number of mouth ulcers. I intend to keep using it.
9
No more ulcers
1 people found this helpful
I feel great! I've tried various supplements to prevent mouth ulcers with little success. Unexpectedly, I haven't had any since using this product, likely due to its abundant B vitamins. My trust in "Solgar" has definitely grown.
9
Reduces oral ulcers
1 people found this helpful
Human metabolism requires the B vitamins. After taking them for a while, I no longer experience oral ulcers. The effect is impressive, and I plan to keep taking them.
9
Less frequent ulcers
Vitamin B helps reduce mouth ulcers! I tended to get them easily and often felt fatigued. Since starting this, I'm getting fewer ulcers and have come to realise the importance of vitamin B. The ingredients are excellent!
9
Effectively treats ulcer
3 people found this helpful
Those suffering from stomach ulcers, mouth ulcers, and daily fatigue should consider this product. I was sceptical initially, but after using the socio-vitamin-non-complex along with Ginga Minggae's herbal supplements, it significantly improved my husband's mouth ulcers. The B vitamins here are especially effective; I highly recommend this, but be cautious as the pills are quite large!
9
No more ulcers
I take a mix of vitamin C, iron, and other supplements from the same manufacturer. The capsules are quite large and initially difficult to swallow, but I've grown accustomed to it. Since beginning this regimen, I've been free from the cracked corners of my mouth and ulcers I often experienced in autumn and winter. Vitamin B complex is truly important!
7.5
Prevents mouth ulcers
Since I started this supplement, I'm less prone to mouth ulcers. It's effective for skin issues too. I believe it's a valuable addition to my regimen.
We analyzed the potential connection between folic acid supplementation and gastric ulcers using data from the UK Biobank and advanced statistical methods.

Our findings suggest that folic acid may significantly lower the risk of developing gastric ulcers.

Various robust models reinforced this result, showing consistent outcomes across different analyses.

Ultimately, this research provides genetic evidence supporting the idea that receiving folic acid therapy can be beneficial in reducing gastric ulcer risk.
8
Folic acid has mixed effects
We examined how different doses of folic acid supplementation affect ulcer formation in rats. Male Wistar rats were treated with varying doses for 21 days while gastric ulcers were induced with indomethacin.

We found that a dose of 2 mg/kg significantly reduced gastric lesions, while a higher dose of 3 mg/kg unexpectedly worsened damage. Our results suggest that low doses of folic acid can be protective for the stomach, but high doses could pose risks.

Thus, it appears that moderation is key when considering folic acid for ulcer treatment.
We investigated how benfotiamine might impact stomach ulcers in male rats. The study involved dividing 30 rats into groups receiving different treatments, including benfotiamine at varying doses, following the induction of ulcers using indomethacin.

Our results showed that benfotiamine notably decreased gastric damage and lowered inflammation markers. Specifically, doses of 100 and 200 mg/kg appeared to enhance antioxidant levels and reduce tissue damage.

However, while these findings are promising, more research is needed to fully understand the mechanisms at play and assess benfotiamine's potential for human treatment.
8
Nicotinamide shows ulcer protection
We explored the effects of nicotinamide on gastric ulcers caused by indomethacin in a laboratory setting. Using a well-established model, we compared the treatment of nicotinamide with sucralfate, a known antiulcer drug.

Our findings revealed that nicotinamide significantly reduced the severity of gastric lesions. It also helped restore vital biochemical parameters affected by the ulcer-inducing drug.

The protective effect of nicotinamide appears to stem from its ability to conserve gastric mucus and nitric oxide, improve gastric microvascular permeability, and exert antioxidant actions.

References

  1. Li F, Huang F, Tang Y, Zhang F, Jiang H, et al. Causal association of folic acid supplementary therapy and gastric ulcer: a Mendelian randomisation study. Br J Nutr. 2024;132:1348. doi:10.1017/S0007114524002368
  2. Shokati Sayyad M, Khanjani MH, Amirbeik M, Seyedabadi M, Talebpour Amiri F, et al. The protective effect of benfotiamine on gastric ulcers in male rats: an experimental study. J Mol Histol. 2024;55:863. doi:10.1007/s10735-024-10237-x
  3. Hellings IR, Larsen S. ImproWin® in the treatment of gastric ulceration of the squamous mucosa in trotting racehorses. Acta Vet Scand. 2014;56:13. doi:10.1186/1751-0147-56-13
  4. Ajeigbe K, Oladejo E, Emikpe B, Asuk A, Olaleye S. The dual modulatory effect of folic acid supplementation on indomethacin-induced gastropathy in the rat. Turk J Gastroenterol. 2012;23:639.
  5. Pimple BP, Kadam PV, Patil MJ. Protective effect of Luffa acutangula extracts on gastric ulceration in NIDDM rats: role of gastric mucosal glycoproteins and antioxidants. Asian Pac J Trop Med. 2012;5:610. doi:10.1016/S1995-7645(12)60126-6
  6. Abdallah DM. Nicotinamide alleviates indomethacin-induced gastric ulcers: a novel antiulcer agent. Eur J Pharmacol. 2010;627:276. doi:10.1016/j.ejphar.2009.10.037
  7. Cui J, Lin W, Ma X, Wang J. Clinical Evaluation and Therapeutic Effects of Combination Treatment with Mecobalamin + Vitamin E in Recurrent Oral Ulcer. Clin Ther. 2022;44:123. doi:10.1016/j.clinthera.2021.10.015
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