' 
SCIENTIFIC SCORE
Moderately Effective
Based on 5 Researches
8.4
USERS' SCORE
Medium or Average
Based on 7 Reviews
6.4
Supplement Facts
Serving Size: 1 Vegetable Capsule
Amount Per Serving
%DV
Thiamin (vitamin B1) (as thiamine mononitrate)
50 mcg
4,167%
Riboflavin (vitamin B2)
50 mg
3,846%
Niacin (vitamin B3) (as niacinamide)
50 mg
313%
Vitamin B6 (as pyridoxine HCl)
50 mg
2,941%
Folate
666 mcg DFE(400 mcg folic acid)
167%
Vitamin B12 (as cyanocobalamin)
50 mcg
2,083%
Biotin (as D-biotin)
50 mcg
167%
Pantothenic Acid (vitamin B5) (as D-ca pantothenate)
50 mg
1,000%
Choline (as choline bitartrate)
21 mg
4%
Inositol
50 mg
**
Herbal Powdered Blend(kelp [plant] , acerola extract complex [fruit], alfalfa [leaf and stem], parsley [leaf], rose hips [fruit], watercress [herb])
3.5 mg
**
Top Medical Research Studies
9
VB6 helps heart recovery post-AMI
Vitamin B6 allosterically activates AMPK to promote postischemic angiogenesis in mice.
High relevance for heart health
We explored how vitamin B6 (VB6) supports heart recovery post-heart attack. In our study, we found that VB6 encourages angiogenesis, which is crucial for healing. Through experiments, we noticed that VB6 helps in cell migration and blood vessel formation by activating a specific protein that plays a key role in these processes. Additionally, long-term use of VB6 improved heart function in mice. While these findings are promising, it’s important to note that further research is necessary to fully understand VB6's effects in humans.
Read More
9
Vitamin B-6 mitigates heart failure risk
Vitamin B-6 Prevents Heart Failure with Preserved Ejection Fraction Through Downstream of Kinase 3 in a Mouse Model.
High relevance in heart disease
We looked into whether vitamin B-6 could help prevent heart failure with preserved ejection fraction (HFpEF) in a mouse model. By using a high-fat diet and other supplements, we created conditions for HFpEF and tested the effects of vitamin B-6 on cardiac function.
The results showed that co-administering vitamin B-6 improved heart function and reduced harmful phenotypic changes in heart macrophages. However, these benefits disappeared in mice lacking a specific protein called DOK3. Overall, vitamin B-6 appears to help mitigate HFpEF by supporting DOK3 signaling and inhibiting detrimental macrophage changes.
The results showed that co-administering vitamin B-6 improved heart function and reduced harmful phenotypic changes in heart macrophages. However, these benefits disappeared in mice lacking a specific protein called DOK3. Overall, vitamin B-6 appears to help mitigate HFpEF by supporting DOK3 signaling and inhibiting detrimental macrophage changes.
Read More
8
Long-term VB1 maintenance improves outcomes
Long-Term Maintenance of Normal Serum Vitamin B Levels Is Associated with Better Outcomes in Patients with Heart Failure.
High relevance to heart health
We explored the impact of long-term vitamin B1 (VB1) maintenance on heart failure (HF) outcomes through a study involving 88 patients. These patients were divided into three groups based on their VB1 levels: a control group with normal levels, a group receiving short-term supplementation, and a group focused on long-term maintenance of normal levels.
The results showed that those who maintained normal VB1 levels experienced better health outcomes compared to those in the other groups. Our findings indicate that consistent VB1 management could be crucial for enhancing HF therapy and reducing risks of hospitalization and cardiovascular death.
The results showed that those who maintained normal VB1 levels experienced better health outcomes compared to those in the other groups. Our findings indicate that consistent VB1 management could be crucial for enhancing HF therapy and reducing risks of hospitalization and cardiovascular death.
Read More
Most Useful Reviews
2.5
Overdose symptoms
Be careful! I experienced a sharp drop in blood pressure after three days, along with arm and leg tremors, dizziness, and weakness. I suspect an overdose of vitamin B1 as my symptoms diminished after stopping the vitamins. Not everyone may tolerate these vitamins well.
Read More
3.5
Increased heart rate
I didn’t like these vitamins as they seemed to raise my heart rate to 110 and caused anxiety, depression, and insomnia after three days. I now take one capsule weekly without negative effects, hoping to gently support my heart system.
Read More
8.3
Excellent results
B vitamins were prescribed for my husband due to Minere's disease, related to vascular issues and dizziness. We chose Solgar for its reputation. He’s been taking it once daily for over six months with excellent results, but I’m cautious about overdosing as B vitamins can be dangerous.
Read More
Medical Researches
SCIENTIFIC SCORE
Moderately Effective
Based on 5 Researches
8.4
- All Researches
9
VB6 helps heart recovery post-AMI
Vitamin B6 allosterically activates AMPK to promote postischemic angiogenesis in mice.
High relevance for heart health
We explored how vitamin B6 (VB6) supports heart recovery post-heart attack. In our study, we found that VB6 encourages angiogenesis, which is crucial for healing. Through experiments, we noticed that VB6 helps in cell migration and blood vessel formation by activating a specific protein that plays a key role in these processes. Additionally, long-term use of VB6 improved heart function in mice. While these findings are promising, it’s important to note that further research is necessary to fully understand VB6's effects in humans.
Read More
9
Vitamin B-6 mitigates heart failure risk
Vitamin B-6 Prevents Heart Failure with Preserved Ejection Fraction Through Downstream of Kinase 3 in a Mouse Model.
High relevance in heart disease
We looked into whether vitamin B-6 could help prevent heart failure with preserved ejection fraction (HFpEF) in a mouse model. By using a high-fat diet and other supplements, we created conditions for HFpEF and tested the effects of vitamin B-6 on cardiac function.
The results showed that co-administering vitamin B-6 improved heart function and reduced harmful phenotypic changes in heart macrophages. However, these benefits disappeared in mice lacking a specific protein called DOK3. Overall, vitamin B-6 appears to help mitigate HFpEF by supporting DOK3 signaling and inhibiting detrimental macrophage changes.
The results showed that co-administering vitamin B-6 improved heart function and reduced harmful phenotypic changes in heart macrophages. However, these benefits disappeared in mice lacking a specific protein called DOK3. Overall, vitamin B-6 appears to help mitigate HFpEF by supporting DOK3 signaling and inhibiting detrimental macrophage changes.
Read More
8
MTHFR gene impacts heart disease outcomes
MTHFR C677T gene polymorphism in patients with coronary heart disease and hypertension treated with enalapril and folic acid: implications for prognosis.
High relevance to prognosis
We investigated how a specific gene variation (MTHFR C677T) influences the outcome for patients with coronary heart disease and hypertension receiving folic acid and enalapril.
Over 540 patients were studied, dividing them into groups that received folic acid or standard treatment.
Our results revealed that patients who took folic acid had better outcomes, including lower rates of cardiovascular events, compared to those who did not. This indicates that folic acid supplementation may enhance treatment success for these high-risk patients.
Over 540 patients were studied, dividing them into groups that received folic acid or standard treatment.
Our results revealed that patients who took folic acid had better outcomes, including lower rates of cardiovascular events, compared to those who did not. This indicates that folic acid supplementation may enhance treatment success for these high-risk patients.
Read More
8
B vitamins may prevent cardiac crises
Folate as a potential treatment for lethal ventricular arrhythmias in TANGO2-deficiency disorder.
High relevance for cardiac treatment
In our exploration of TANGO2-deficiency disorder, we found that cardiac arrhythmias linked to this genetic condition are often resistant to standard treatments.
Using innovative patient-derived stem cell models, we identified that high doses of folate (vitamin B9) can significantly reduce arrhythmias.
Clinical data also indicated that multivitamin and B complex intake may lower the risk of serious heart issues in affected individuals.
This suggests that B vitamins might offer a life-saving strategy for managing dangerous cardiac events in patients with this disorder.
Using innovative patient-derived stem cell models, we identified that high doses of folate (vitamin B9) can significantly reduce arrhythmias.
Clinical data also indicated that multivitamin and B complex intake may lower the risk of serious heart issues in affected individuals.
This suggests that B vitamins might offer a life-saving strategy for managing dangerous cardiac events in patients with this disorder.
Read More
8
Long-term VB1 maintenance improves outcomes
Long-Term Maintenance of Normal Serum Vitamin B Levels Is Associated with Better Outcomes in Patients with Heart Failure.
High relevance to heart health
We explored the impact of long-term vitamin B1 (VB1) maintenance on heart failure (HF) outcomes through a study involving 88 patients. These patients were divided into three groups based on their VB1 levels: a control group with normal levels, a group receiving short-term supplementation, and a group focused on long-term maintenance of normal levels.
The results showed that those who maintained normal VB1 levels experienced better health outcomes compared to those in the other groups. Our findings indicate that consistent VB1 management could be crucial for enhancing HF therapy and reducing risks of hospitalization and cardiovascular death.
The results showed that those who maintained normal VB1 levels experienced better health outcomes compared to those in the other groups. Our findings indicate that consistent VB1 management could be crucial for enhancing HF therapy and reducing risks of hospitalization and cardiovascular death.
Read More
User Reviews
USERS' SCORE
Medium or Average
Based on 7 Reviews
6.4
- All Reviews
- Positive Reviews
- Negative Reviews
2.5
Overdose symptoms
Be careful! I experienced a sharp drop in blood pressure after three days, along with arm and leg tremors, dizziness, and weakness. I suspect an overdose of vitamin B1 as my symptoms diminished after stopping the vitamins. Not everyone may tolerate these vitamins well.
3.5
Increased heart rate
I didn’t like these vitamins as they seemed to raise my heart rate to 110 and caused anxiety, depression, and insomnia after three days. I now take one capsule weekly without negative effects, hoping to gently support my heart system.
8.3
Excellent results
B vitamins were prescribed for my husband due to Minere's disease, related to vascular issues and dizziness. We chose Solgar for its reputation. He’s been taking it once daily for over six months with excellent results, but I’m cautious about overdosing as B vitamins can be dangerous.
Read More
8
Preventive measure
I received the long-awaited B complex. Solgar inspires confidence. I take it to my parents as a preventive measure for their health, as a deficiency of B vitamins can lead to an increase in homocysteine and subsequently heart disease. I wish everyone good health.
2.5
Excessive stimulation
I found the dosage of these vitamins too potent for me, causing strong overexcitement rather than helping with hair loss. It also increased the strain on my heart, leading to no improvement in my hair condition.
