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Solgar Solgar B-Complex "100"
SCIENTIFIC SCORE
Possibly Effective
Based on 4 Researches
7.8
USERS' SCORE
Medium or Average
Based on 4 Reviews
6.1
Supplement Facts
Serving Size:  1 Vegetable Capsule
Amount Per Serving
%DV
Thiamin (vitamin B1) (as thiamin mononitrate)
100 mg
8,333%
Riboflavin (vitamin B2)
100 mg
7,692%
Niacin (vitamin B3) (as niacinamide)
100 mg
625%
Vitamin B6 (as pyridoxine HCl)
100 mg
5,882%
Folate
666 mcg DFE (400 mcg folic acid)
167%
Vitamin B12 (as cyanocobalamin)
100 mcg
4,167%
Biotin (as d-biotin)
100 mcg
333%
Pantothenic Acid (vitamin B5) (as d-calcium pantothenate)
100 mg
2,000%
Choline (as choline bitartrate)
20 mg
4%
Inositol
100 mg
**

Top Medical Research Studies

9
Methylcobalamin protects against liver failure
Methylcobalamin protects against liver failure via engaging gasdermin E.
High relevance to liver treatment
We investigated how methylcobalamin, a form of vitamin B12, affects liver failure, particularly in cases of cholestasis. Methylcobalamin showed promise as it directly binds to and inhibits Gasdermin E, a protein linked to liver cell death.

In mouse models, this vitamin significantly reduced liver inflammation and damage, lowering mortality rates. These findings suggest that methylcobalamin could be a potential treatment option for preventing severe liver failure and related health issues.
Read More
7
Vitamin B6 may protect liver health
The gut microbiota-produced vitamin B6 mitigates alcohol-associated liver disease by attenuating hepatic oxidative stress damage.
Moderately relevant to liver health
We investigated the connection between vitamin B6 and alcohol-associated liver disease (ALD) using a mouse model. Through a detailed analysis of the gut microbiota, we observed that disruptions significantly lowered vitamin B6 production. This reduction heightened oxidative stress and worsened liver damage. Our results indicate that maintaining vitamin B6 levels could be vital in protecting against ALD progression by influencing important metabolic processes. Despite some promising findings, the protective effects of vitamin B6 against ALD warrant further exploration before drawing definitive conclusions.
Read More
7
Vitamin B and Folate Related to Mortality
Associations of serum folate and vitamin B levels with all-cause mortality among patients with metabolic dysfunction associated steatotic liver disease: a prospective cohort study.
High relevance to liver disease research
We explored how serum folate and vitamin B levels relate to all-cause mortality among individuals with metabolic dysfunction-associated steatotic liver disease (MASLD). Utilizing data from the Third National Health and Nutrition Examination Survey, we followed nearly 3,636 MASLD subjects for over 20 years.

Our findings indicated that lower levels of these vitamins were tied to a higher risk of mortality. Specifically, individuals with serum vitamin B and folate levels above the median experienced significant reductions in mortality risk, underscoring the potential importance of these nutrients for liver health.
Read More

Most Useful Reviews

5.8
Positive liver cleansing
I found this product excellent for liver cleansing and detoxification. The ingredients and dosage are suitable for my age. Despite having no taste, it seems effective and beneficial for my health, encouraging radical cleaning of the liver.
Read More
0
Liver pain experienced
I mistakenly took a high dosage of these B vitamins, thinking they would be beneficial. After a month, I suffered severe pain, which I later realised was linked to liver disease caused by hypervitaminosis. I felt terrible, with inability to concentrate and constant weakness. I regret taking these vitamins thoughtlessly, as they turned out to be harmful.
Read More
1.3
Liver discomfort noted
This product obviously had a dosage meant for horses. After taking it for three days, I started to feel pain in my liver. I assumed this was due to the vitamins, so I stopped using it and switched to standard B6 from the pharmacy. I only regret the money wasted.
Read More

Medical Researches

SCIENTIFIC SCORE
Possibly Effective
Based on 4 Researches
7.8
  • All Researches
9
Methylcobalamin protects against liver failure
Methylcobalamin protects against liver failure via engaging gasdermin E.
High relevance to liver treatment
We investigated how methylcobalamin, a form of vitamin B12, affects liver failure, particularly in cases of cholestasis. Methylcobalamin showed promise as it directly binds to and inhibits Gasdermin E, a protein linked to liver cell death.

In mouse models, this vitamin significantly reduced liver inflammation and damage, lowering mortality rates. These findings suggest that methylcobalamin could be a potential treatment option for preventing severe liver failure and related health issues.
Read More
8
Antioxidants may protect liver health
Effects of adenosine triphosphate, thiamine pyrophosphate, melatonin, and liv-52 on subacute pyrazinamide proliferation hepatotoxicity in rats.
High relevance to liver therapy
We explored the impact of four potential protective agents—ATP, thiamine pyrophosphate, melatonin, and Liv-52—against liver damage caused by the antibiotic pyrazinamide in a rat model.

In a carefully designed study with 36 rats split into various treatment groups, we administered these compounds alongside pyrazinamide for four weeks.

Our findings showed that these treatments effectively protected liver tissues from damage due to oxidative stress, as measured by various biochemical and histopathological analyses.

This suggests a promising avenue for enhancing liver health during pyrazinamide therapy.
Read More
7
Vitamin B and Folate Related to Mortality
Associations of serum folate and vitamin B levels with all-cause mortality among patients with metabolic dysfunction associated steatotic liver disease: a prospective cohort study.
High relevance to liver disease research
We explored how serum folate and vitamin B levels relate to all-cause mortality among individuals with metabolic dysfunction-associated steatotic liver disease (MASLD). Utilizing data from the Third National Health and Nutrition Examination Survey, we followed nearly 3,636 MASLD subjects for over 20 years.

Our findings indicated that lower levels of these vitamins were tied to a higher risk of mortality. Specifically, individuals with serum vitamin B and folate levels above the median experienced significant reductions in mortality risk, underscoring the potential importance of these nutrients for liver health.
Read More
7
Vitamin B6 may protect liver health
The gut microbiota-produced vitamin B6 mitigates alcohol-associated liver disease by attenuating hepatic oxidative stress damage.
Moderately relevant to liver health
We investigated the connection between vitamin B6 and alcohol-associated liver disease (ALD) using a mouse model. Through a detailed analysis of the gut microbiota, we observed that disruptions significantly lowered vitamin B6 production. This reduction heightened oxidative stress and worsened liver damage. Our results indicate that maintaining vitamin B6 levels could be vital in protecting against ALD progression by influencing important metabolic processes. Despite some promising findings, the protective effects of vitamin B6 against ALD warrant further exploration before drawing definitive conclusions.
Read More

User Reviews

USERS' SCORE
Medium or Average
Based on 4 Reviews
6.1
  • All Reviews
  • Positive Reviews
  • Negative Reviews
5.8
Positive liver cleansing
I found this product excellent for liver cleansing and detoxification. The ingredients and dosage are suitable for my age. Despite having no taste, it seems effective and beneficial for my health, encouraging radical cleaning of the liver.
0
Liver pain experienced
I mistakenly took a high dosage of these B vitamins, thinking they would be beneficial. After a month, I suffered severe pain, which I later realised was linked to liver disease caused by hypervitaminosis. I felt terrible, with inability to concentrate and constant weakness. I regret taking these vitamins thoughtlessly, as they turned out to be harmful.
Read More
1.3
Liver discomfort noted
This product obviously had a dosage meant for horses. After taking it for three days, I started to feel pain in my liver. I assumed this was due to the vitamins, so I stopped using it and switched to standard B6 from the pharmacy. I only regret the money wasted.
1.3
Hepatic migraines experienced
I am uncertain whether it was due to high dosage or a specific ingredient, but this supplement led to hepatic migraines for me. Although I trust Solgar's quality, I was disappointed by its effect on my liver.
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