'
SCIENTIFIC SCORE
Most Likely Effective
Based on 4 Researches
8.8
USERS' SCORE
Very Good
Based on 1 Reviews
8
Supplement Facts
Serving Size:  1 Vegetable Capsule
Amount Per Serving
%DV
Biotin
5,000 mcg
16,667%
Calcium (as dicalcium phosphate)
148 mg
11%
Phosphorous (as dicalcium phosphate)
115 mg
9%

Top Medical Research Studies

9.5
Biotin treatment for eczema effectiveness
Biotinidase deficiency characterized by skin and hair findings.
Direct relevance to biotin usage
We explored a unique case involving a girl diagnosed with biotinidase deficiency, a rare inherited metabolic condition that can lead to notable skin and hair issues. The report highlighted her struggles with intractable dermatitis, yellow hair, and alopecia—symptoms that pointed to the underlying deficiency.

Biotin, a vital nutrient, was administered at a dose of 20 mg per day as a replacement therapy. Within one month, we observed a substantial improvement in her dermatitis, and by the three-month mark, her hair color had returned to near normal. The significant change in her condition illustrates how effective biotin can be for individuals suffering from both biotinidase deficiency and associated eczema-like symptoms.

This case serves as a reminder for healthcare providers, especially dermatologists, to consider biotinidase deficiency as a potential factor when treating similar conditions in children. By recognizing the importance of biotin, we can help improve health outcomes for those experiencing dermatological challenges tied to this rare disorder.
Read More
9.5
Biotin supplementation improves eczema
Normalization of low biotinidase activity in a child with biotin deficiency after biotin supplementation.
Study highlights biotin's efficacy
We observed the case of a Japanese boy who suffered from a severe skin rash caused by biotin deficiency. This child had unique health challenges, including an intracranial malformation, and was fed through a tube using a single formula for more than a year. This feeding method led to a deficiency in biotin, an essential nutrient known for its role in maintaining skin health and other bodily functions.

Upon analysis, we found the boy had low biotinidase activity, which is important for processing biotin in the body. The good news is that after introducing biotin supplementation into his routine, not only did his skin rash improve significantly, but his biotinidase activity also returned to normal levels.

This case suggests that biotin plays a key role in regulating the production of biotinidase, highlighting its potential benefits in treating conditions like eczema, especially when linked to a deficiency. It's a promising finding, although we must acknowledge that this is a report based on a single patient’s experience.
Read More
9
Investigated biotin for eczema
Screening of carnitine and biotin deficiencies on tandem mass spectrometry.
Biotin's effect on eczema
We explored the potential benefits of biotin in treating eczema, particularly in pediatric patients. In the context of a study involving 42 children, we assessed nutritional deficiencies that might be affecting their skin health, especially considering some were on enteral feeding.

Among the findings, we discovered one patient with therapy-resistant eczema responded positively to treatment with additional biotin. Alongside this treatment, they also switched to a non-hydrolyzed formula. However, since biotin was administered in combination with other interventions, we cannot conclude that biotin alone was responsible for the improvement.

Overall, while the results suggest that biotin may have a role in addressing eczema in specific cases, the effects are not isolated. Further research would be needed to fully understand the impact of biotin on eczema management.
Read More

Most Useful Reviews

8
Reduced eczema frequency
Although I haven't noticed much change in my nails yet, my eczema has become less bothersome. Biotin appears to be positively affecting my intestines; I no longer suffer from constipation and have regular bowel movements. Additionally, I find I'm less anxious, which I attribute to getting adequate sleep as I've started going to bed earlier.
Read More

Medical Researches

SCIENTIFIC SCORE
Most Likely Effective
Based on 4 Researches
8.8
9.5
Biotin treatment for eczema effectiveness
Biotinidase deficiency characterized by skin and hair findings.
Direct relevance to biotin usage
We explored a unique case involving a girl diagnosed with biotinidase deficiency, a rare inherited metabolic condition that can lead to notable skin and hair issues. The report highlighted her struggles with intractable dermatitis, yellow hair, and alopecia—symptoms that pointed to the underlying deficiency.

Biotin, a vital nutrient, was administered at a dose of 20 mg per day as a replacement therapy. Within one month, we observed a substantial improvement in her dermatitis, and by the three-month mark, her hair color had returned to near normal. The significant change in her condition illustrates how effective biotin can be for individuals suffering from both biotinidase deficiency and associated eczema-like symptoms.

This case serves as a reminder for healthcare providers, especially dermatologists, to consider biotinidase deficiency as a potential factor when treating similar conditions in children. By recognizing the importance of biotin, we can help improve health outcomes for those experiencing dermatological challenges tied to this rare disorder.
Read More
9.5
Biotin supplementation improves eczema
Normalization of low biotinidase activity in a child with biotin deficiency after biotin supplementation.
Study highlights biotin's efficacy
We observed the case of a Japanese boy who suffered from a severe skin rash caused by biotin deficiency. This child had unique health challenges, including an intracranial malformation, and was fed through a tube using a single formula for more than a year. This feeding method led to a deficiency in biotin, an essential nutrient known for its role in maintaining skin health and other bodily functions.

Upon analysis, we found the boy had low biotinidase activity, which is important for processing biotin in the body. The good news is that after introducing biotin supplementation into his routine, not only did his skin rash improve significantly, but his biotinidase activity also returned to normal levels.

This case suggests that biotin plays a key role in regulating the production of biotinidase, highlighting its potential benefits in treating conditions like eczema, especially when linked to a deficiency. It's a promising finding, although we must acknowledge that this is a report based on a single patient’s experience.
Read More
9
Investigated biotin for eczema
Screening of carnitine and biotin deficiencies on tandem mass spectrometry.
Biotin's effect on eczema
We explored the potential benefits of biotin in treating eczema, particularly in pediatric patients. In the context of a study involving 42 children, we assessed nutritional deficiencies that might be affecting their skin health, especially considering some were on enteral feeding.

Among the findings, we discovered one patient with therapy-resistant eczema responded positively to treatment with additional biotin. Alongside this treatment, they also switched to a non-hydrolyzed formula. However, since biotin was administered in combination with other interventions, we cannot conclude that biotin alone was responsible for the improvement.

Overall, while the results suggest that biotin may have a role in addressing eczema in specific cases, the effects are not isolated. Further research would be needed to fully understand the impact of biotin on eczema management.
Read More
7
Biotin improves overall health outcomes
[Diagnosis and treatment of biotinidase deficiency-clinical study of six patients].
Moderate impact on eczema noted
We explored how biotin treatment affects patients with biotinidase deficiency, focusing on their clinical features, which include skin conditions like eczema. In our study, six patients ranging from only a few months old to 14 years displayed a variety of neurological and dermatological symptoms.

Among these, Case 2 had eczema that started at 7 months old, and Case 6 also dealt with eczema and additional skin issues such as alopecia. Biotin supplements were given to most of the patients, and we saw that they made notable improvements in their overall health.

While biotin appeared beneficial in addressing general symptoms of biotinidase deficiency, particularly regarding nervous system function, the specific impact on eczema was less clear and may not have been as straightforward. Our observation suggests that early diagnosis and biotin supplementation play significant roles in improving outcomes for these patients overall.
Read More

User Reviews

USERS' SCORE
Very Good
Based on 1 Reviews
8
8
Reduced eczema frequency
Although I haven't noticed much change in my nails yet, my eczema has become less bothersome. Biotin appears to be positively affecting my intestines; I no longer suffer from constipation and have regular bowel movements. Additionally, I find I'm less anxious, which I attribute to getting adequate sleep as I've started going to bed earlier.
Read More
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