Last update
5/15/2026
Reviewed By
Overview
SCIENTIFIC SCORE
Questionable
Based on 2 Researches
6.8
USERS' SCORE
Moderately Good
Based on 13 Reviews
7.3
Supplement Facts
Serving Size: 1 Vegetable Capsule
Amount Per Serving
%DV
Iron (as iron bisglycinate chelate†)
25 mg
139%
Top Medical Research Studies
4
We explored how low-level iron supplementation impacts the gut microbiota in individuals with Irritable Bowel Syndrome (IBS) and in healthy donors. To do this, we conducted anaerobic, pH-controlled in vitro batch cultures using fecal samples from both groups, supplemented with various forms of iron, including ferrous sulphate, nanoparticulate iron, and pea ferritin.
Our findings revealed that IBS participants had distinct microbial profiles compared to their healthy counterparts. Interestingly, we observed that the different sources of iron we used did not have a negative effect on the overall microbial populations. Both pea ferritin and nanoparticulate iron showed similar outcomes, while ferrous sulphate appeared to enhance certain beneficial bacteria.
Additionally, we measured the production of metabolites and found that there was no harmful shift towards increased proteolysis. These results suggest that low doses of iron from the three sources tested are unlikely to be detrimental to the gut microbiota, giving us new insights into the potential for iron supplementation in managing gut health, especially for those with IBS.
This is the first time we've tested fermentation of pea ferritin, which adds an exciting dimension to our understanding of dietary iron sources and gut health.
Our findings revealed that IBS participants had distinct microbial profiles compared to their healthy counterparts. Interestingly, we observed that the different sources of iron we used did not have a negative effect on the overall microbial populations. Both pea ferritin and nanoparticulate iron showed similar outcomes, while ferrous sulphate appeared to enhance certain beneficial bacteria.
Additionally, we measured the production of metabolites and found that there was no harmful shift towards increased proteolysis. These results suggest that low doses of iron from the three sources tested are unlikely to be detrimental to the gut microbiota, giving us new insights into the potential for iron supplementation in managing gut health, especially for those with IBS.
This is the first time we've tested fermentation of pea ferritin, which adds an exciting dimension to our understanding of dietary iron sources and gut health.
Read More
9.5
Celiac disease linked to IBS symptoms
We explored a fascinating case of a 30-year-old patient who was initially diagnosed with irritable bowel syndrome (IBS) due to vague abdominal symptoms. However, this diagnosis was later challenged when he presented with iron deficiency anemia in our clinic.
Upon further investigation for the cause of his anemia, we discovered he actually had celiac disease, confirmed by positive serological tests and a small bowel biopsy. After starting a gluten-free diet and taking iron supplements, we observed a complete improvement in both his abdominal symptoms and his anemia.
This case brings to light the complexities of diagnosing gastrointestinal issues. It emphasizes the need for routine screening for celiac disease in patients who may present with symptoms that could easily be misattributed to IBS—especially when iron deficiency anemia is involved.
Upon further investigation for the cause of his anemia, we discovered he actually had celiac disease, confirmed by positive serological tests and a small bowel biopsy. After starting a gluten-free diet and taking iron supplements, we observed a complete improvement in both his abdominal symptoms and his anemia.
This case brings to light the complexities of diagnosing gastrointestinal issues. It emphasizes the need for routine screening for celiac disease in patients who may present with symptoms that could easily be misattributed to IBS—especially when iron deficiency anemia is involved.
Read More
Most Useful Reviews
9
Increases iron
1 people found this helpful
This supplement increases iron levels without causing bowel issues.
Read More
10
Super iron!
Solgar iron is fantastic! It’s easy to take and doesn’t lead to constipation or bowel disturbances.
Read More
10
Bowel movements unaffected
This iron supplement does not seem to impact my bowel movements as other products have.
Read More
Medical Researches
SCIENTIFIC SCORE
Questionable
Based on 2 Researches
6.8
- All Researches
9.5
Celiac disease linked to IBS symptoms
We explored a fascinating case of a 30-year-old patient who was initially diagnosed with irritable bowel syndrome (IBS) due to vague abdominal symptoms. However, this diagnosis was later challenged when he presented with iron deficiency anemia in our clinic.
Upon further investigation for the cause of his anemia, we discovered he actually had celiac disease, confirmed by positive serological tests and a small bowel biopsy. After starting a gluten-free diet and taking iron supplements, we observed a complete improvement in both his abdominal symptoms and his anemia.
This case brings to light the complexities of diagnosing gastrointestinal issues. It emphasizes the need for routine screening for celiac disease in patients who may present with symptoms that could easily be misattributed to IBS—especially when iron deficiency anemia is involved.
Upon further investigation for the cause of his anemia, we discovered he actually had celiac disease, confirmed by positive serological tests and a small bowel biopsy. After starting a gluten-free diet and taking iron supplements, we observed a complete improvement in both his abdominal symptoms and his anemia.
This case brings to light the complexities of diagnosing gastrointestinal issues. It emphasizes the need for routine screening for celiac disease in patients who may present with symptoms that could easily be misattributed to IBS—especially when iron deficiency anemia is involved.
Read More
4
We explored how low-level iron supplementation impacts the gut microbiota in individuals with Irritable Bowel Syndrome (IBS) and in healthy donors. To do this, we conducted anaerobic, pH-controlled in vitro batch cultures using fecal samples from both groups, supplemented with various forms of iron, including ferrous sulphate, nanoparticulate iron, and pea ferritin.
Our findings revealed that IBS participants had distinct microbial profiles compared to their healthy counterparts. Interestingly, we observed that the different sources of iron we used did not have a negative effect on the overall microbial populations. Both pea ferritin and nanoparticulate iron showed similar outcomes, while ferrous sulphate appeared to enhance certain beneficial bacteria.
Additionally, we measured the production of metabolites and found that there was no harmful shift towards increased proteolysis. These results suggest that low doses of iron from the three sources tested are unlikely to be detrimental to the gut microbiota, giving us new insights into the potential for iron supplementation in managing gut health, especially for those with IBS.
This is the first time we've tested fermentation of pea ferritin, which adds an exciting dimension to our understanding of dietary iron sources and gut health.
Our findings revealed that IBS participants had distinct microbial profiles compared to their healthy counterparts. Interestingly, we observed that the different sources of iron we used did not have a negative effect on the overall microbial populations. Both pea ferritin and nanoparticulate iron showed similar outcomes, while ferrous sulphate appeared to enhance certain beneficial bacteria.
Additionally, we measured the production of metabolites and found that there was no harmful shift towards increased proteolysis. These results suggest that low doses of iron from the three sources tested are unlikely to be detrimental to the gut microbiota, giving us new insights into the potential for iron supplementation in managing gut health, especially for those with IBS.
This is the first time we've tested fermentation of pea ferritin, which adds an exciting dimension to our understanding of dietary iron sources and gut health.
Read More
User Reviews
USERS' SCORE
Moderately Good
Based on 13 Reviews
7.3
- All Reviews
- Positive Reviews
- Negative Reviews
9
Increases iron
1 people found this helpful
This supplement increases iron levels without causing bowel issues.
Read More
10
Super iron!
Solgar iron is fantastic! It’s easy to take and doesn’t lead to constipation or bowel disturbances.
Read More
10
Bowel movements unaffected
This iron supplement does not seem to impact my bowel movements as other products have.
Read More
9
No constipation
As a pregnant woman, I found this supplement did not cause constipation, as claimed. There was no unpleasant aftertaste.
Read More
0
Constipation issues
3 people found this helpful
I had a bad experience with this iron. It caused constipation and bowel problems. I would recommend trying Hema instead, which does not lead to these issues.
Read More
Frequently Asked Questions
7
Normal function restored
I bought this for my mother. Initially, there were bowel issues, but they normalised after some time. Her haemoglobin levels returned to normal after months of use, so I plan to buy it again.
9
Post childbirth recovery
After childbirth, I quickly raised my haemoglobin and ferritin without experiencing bowel problems.
10
Bowel movements unaffected
This iron supplement does not seem to impact my bowel movements as other products have.
9
No bowel issues
I purchased these iron supplements to boost my intake. Unlike others, this one did not cause constipation, which I appreciated.
0
Painful bowel movements
Although this iron tablet was easy on my stomach, taking it daily resulted in painful bowel movements, making my stool hard and dark.
4
We explored how low-level iron supplementation impacts the gut microbiota in individuals with Irritable Bowel Syndrome (IBS) and in healthy donors. To do this, we conducted anaerobic, pH-controlled in vitro batch cultures using fecal samples from both groups, supplemented with various forms of iron, including ferrous sulphate, nanoparticulate iron, and pea ferritin.
Our findings revealed that IBS participants had distinct microbial profiles compared to their healthy counterparts. Interestingly, we observed that the different sources of iron we used did not have a negative effect on the overall microbial populations. Both pea ferritin and nanoparticulate iron showed similar outcomes, while ferrous sulphate appeared to enhance certain beneficial bacteria.
Additionally, we measured the production of metabolites and found that there was no harmful shift towards increased proteolysis. These results suggest that low doses of iron from the three sources tested are unlikely to be detrimental to the gut microbiota, giving us new insights into the potential for iron supplementation in managing gut health, especially for those with IBS.
This is the first time we've tested fermentation of pea ferritin, which adds an exciting dimension to our understanding of dietary iron sources and gut health.
Our findings revealed that IBS participants had distinct microbial profiles compared to their healthy counterparts. Interestingly, we observed that the different sources of iron we used did not have a negative effect on the overall microbial populations. Both pea ferritin and nanoparticulate iron showed similar outcomes, while ferrous sulphate appeared to enhance certain beneficial bacteria.
Additionally, we measured the production of metabolites and found that there was no harmful shift towards increased proteolysis. These results suggest that low doses of iron from the three sources tested are unlikely to be detrimental to the gut microbiota, giving us new insights into the potential for iron supplementation in managing gut health, especially for those with IBS.
This is the first time we've tested fermentation of pea ferritin, which adds an exciting dimension to our understanding of dietary iron sources and gut health.
9.5
Celiac disease linked to IBS symptoms
We explored a fascinating case of a 30-year-old patient who was initially diagnosed with irritable bowel syndrome (IBS) due to vague abdominal symptoms. However, this diagnosis was later challenged when he presented with iron deficiency anemia in our clinic.
Upon further investigation for the cause of his anemia, we discovered he actually had celiac disease, confirmed by positive serological tests and a small bowel biopsy. After starting a gluten-free diet and taking iron supplements, we observed a complete improvement in both his abdominal symptoms and his anemia.
This case brings to light the complexities of diagnosing gastrointestinal issues. It emphasizes the need for routine screening for celiac disease in patients who may present with symptoms that could easily be misattributed to IBS—especially when iron deficiency anemia is involved.
Upon further investigation for the cause of his anemia, we discovered he actually had celiac disease, confirmed by positive serological tests and a small bowel biopsy. After starting a gluten-free diet and taking iron supplements, we observed a complete improvement in both his abdominal symptoms and his anemia.
This case brings to light the complexities of diagnosing gastrointestinal issues. It emphasizes the need for routine screening for celiac disease in patients who may present with symptoms that could easily be misattributed to IBS—especially when iron deficiency anemia is involved.
References
- Poveda C, Pereira DIA, Lewis M, Walton GE. The Impact of Low-Level Iron Supplements on the Faecal Microbiota of Irritable Bowel Syndrome and Healthy Donors Using In Vitro Batch Cultures. Nutrients. 2020;12. 10.3390/nu12123819
- Elmakki EE. Celiac Disease Initially Misdiagnosed as Irritable Bowel Syndrome: Case Report. Cureus. 2012;4:e71. 10.7759/cureus.71
