Overview
SCIENTIFIC SCORE
Moderately Effective
Based on 4 Researches
8
USERS' SCORE
Good
Based on 109 Reviews
8.6
Supplement Facts
Serving Size: 1 Vegetable Capsule
Amount Per Serving
%DV
Iron (as iron bisglycinate chelate†)
25 mg
139%
Top Medical Research Studies
9
We evaluated how switching to ferric citrate hydrate (FCH) impacts nausea in women with iron deficiency anemia (IDA) who struggled with oral iron. In a multicenter study of 30 patients, those on FCH experienced significant improvements. Nausea scores dropped from 5.7 to 1.7, and the overall incidence of nausea decreased notably. Also, 80% reported better experiences compared to previous treatments.
Overall, our findings suggest that FCH not only enhances medication adherence but also effectively reduces nausea and improves quality of life in these patients.
Overall, our findings suggest that FCH not only enhances medication adherence but also effectively reduces nausea and improves quality of life in these patients.
Read More
9
We conducted a study to examine the effectiveness of a specific iron supplement, emulsified microsomal ferric pyrophosphate (EMFP), in treating iron deficiency anemia among pregnant women. Our focus was not only on improving hemoglobin levels but also on alleviating related symptoms, including nausea.
Within 30 days of starting treatment with EMFP, we observed significant increases in hemoglobin levels, alongside marked improvements in serum ferritin and iron levels. As nausea is a common complaint among pregnant women, we noted a decrease in various symptoms, including nausea, breathlessness, and dizziness, which contributed to a better quality of life for the participants.
Notably, treatment compliance was remarkably high at 99.5%, indicating that the participants were committed to managing their anemia effectively. Importantly, we did not encounter any severe side effects related to the treatment, suggesting a favorable safety profile.
Overall, our findings support the idea that iron treatment can help alleviate nausea and other discomforts related to iron deficiency anemia in pregnancy, positively impacting both mother and baby.
Within 30 days of starting treatment with EMFP, we observed significant increases in hemoglobin levels, alongside marked improvements in serum ferritin and iron levels. As nausea is a common complaint among pregnant women, we noted a decrease in various symptoms, including nausea, breathlessness, and dizziness, which contributed to a better quality of life for the participants.
Notably, treatment compliance was remarkably high at 99.5%, indicating that the participants were committed to managing their anemia effectively. Importantly, we did not encounter any severe side effects related to the treatment, suggesting a favorable safety profile.
Overall, our findings support the idea that iron treatment can help alleviate nausea and other discomforts related to iron deficiency anemia in pregnancy, positively impacting both mother and baby.
Read More
7
We explored the effects of daily versus three times weekly (TIW) oral iron supplementation on nausea in NCAA Division 1 female athletes. The study involved 33 athletes who were either in track and field or soccer. Participants were given either daily doses or TIW doses of ferrous bisglycinate over eight weeks.
Both groups showed an increase in serum ferritin levels, which is a marker of iron stores. However, the TIW regimen resulted in a smaller increase of about 5.17 μg/L, compared to an increase of 12.88 μg/L with the daily regimen. Notably, those taking daily supplements experienced significantly more nausea and constipation than those on the TIW schedule.
While the daily regimen may boost iron levels more effectively, it can come at the cost of increased gastrointestinal discomfort. Meanwhile, the TIW regimen offers a gentler option with fewer side effects, positioning it as a viable alternative for athletes concerned about nausea.
Both groups showed an increase in serum ferritin levels, which is a marker of iron stores. However, the TIW regimen resulted in a smaller increase of about 5.17 μg/L, compared to an increase of 12.88 μg/L with the daily regimen. Notably, those taking daily supplements experienced significantly more nausea and constipation than those on the TIW schedule.
While the daily regimen may boost iron levels more effectively, it can come at the cost of increased gastrointestinal discomfort. Meanwhile, the TIW regimen offers a gentler option with fewer side effects, positioning it as a viable alternative for athletes concerned about nausea.
Read More
Most Useful Reviews
9.5
No nausea noted
A gentle and effective product. I've been using it every other day without any nausea, even on an empty stomach, and my iron levels improved!
Read More
9.5
No nausea experienced
I have dealt with iron deficiency anaemia my entire adult life. I usually maintain my iron levels through diet but turned to Solgar's Gentle Iron when my haemoglobin fell to critical levels. It has low toxicity and is well-absorbed, unlike other supplements that upset my stomach. After taking it, my dizziness and darkening vision when standing quickly improved. I experienced no nausea or pain for five months. I recommend taking iron at night, avoiding food before and after, and combining it with vitamin C.
Read More
0
Severe nausea
This product caused excruciating stomach cramps, diarrhoea, and severe nausea.
Read More
Medical Researches
SCIENTIFIC SCORE
Moderately Effective
Based on 4 Researches
8
- All Researches
9
We conducted a study to examine the effectiveness of a specific iron supplement, emulsified microsomal ferric pyrophosphate (EMFP), in treating iron deficiency anemia among pregnant women. Our focus was not only on improving hemoglobin levels but also on alleviating related symptoms, including nausea.
Within 30 days of starting treatment with EMFP, we observed significant increases in hemoglobin levels, alongside marked improvements in serum ferritin and iron levels. As nausea is a common complaint among pregnant women, we noted a decrease in various symptoms, including nausea, breathlessness, and dizziness, which contributed to a better quality of life for the participants.
Notably, treatment compliance was remarkably high at 99.5%, indicating that the participants were committed to managing their anemia effectively. Importantly, we did not encounter any severe side effects related to the treatment, suggesting a favorable safety profile.
Overall, our findings support the idea that iron treatment can help alleviate nausea and other discomforts related to iron deficiency anemia in pregnancy, positively impacting both mother and baby.
Within 30 days of starting treatment with EMFP, we observed significant increases in hemoglobin levels, alongside marked improvements in serum ferritin and iron levels. As nausea is a common complaint among pregnant women, we noted a decrease in various symptoms, including nausea, breathlessness, and dizziness, which contributed to a better quality of life for the participants.
Notably, treatment compliance was remarkably high at 99.5%, indicating that the participants were committed to managing their anemia effectively. Importantly, we did not encounter any severe side effects related to the treatment, suggesting a favorable safety profile.
Overall, our findings support the idea that iron treatment can help alleviate nausea and other discomforts related to iron deficiency anemia in pregnancy, positively impacting both mother and baby.
Read More
9
We evaluated how switching to ferric citrate hydrate (FCH) impacts nausea in women with iron deficiency anemia (IDA) who struggled with oral iron. In a multicenter study of 30 patients, those on FCH experienced significant improvements. Nausea scores dropped from 5.7 to 1.7, and the overall incidence of nausea decreased notably. Also, 80% reported better experiences compared to previous treatments.
Overall, our findings suggest that FCH not only enhances medication adherence but also effectively reduces nausea and improves quality of life in these patients.
Overall, our findings suggest that FCH not only enhances medication adherence but also effectively reduces nausea and improves quality of life in these patients.
Read More
7
We explored the effects of daily versus three times weekly (TIW) oral iron supplementation on nausea in NCAA Division 1 female athletes. The study involved 33 athletes who were either in track and field or soccer. Participants were given either daily doses or TIW doses of ferrous bisglycinate over eight weeks.
Both groups showed an increase in serum ferritin levels, which is a marker of iron stores. However, the TIW regimen resulted in a smaller increase of about 5.17 μg/L, compared to an increase of 12.88 μg/L with the daily regimen. Notably, those taking daily supplements experienced significantly more nausea and constipation than those on the TIW schedule.
While the daily regimen may boost iron levels more effectively, it can come at the cost of increased gastrointestinal discomfort. Meanwhile, the TIW regimen offers a gentler option with fewer side effects, positioning it as a viable alternative for athletes concerned about nausea.
Both groups showed an increase in serum ferritin levels, which is a marker of iron stores. However, the TIW regimen resulted in a smaller increase of about 5.17 μg/L, compared to an increase of 12.88 μg/L with the daily regimen. Notably, those taking daily supplements experienced significantly more nausea and constipation than those on the TIW schedule.
While the daily regimen may boost iron levels more effectively, it can come at the cost of increased gastrointestinal discomfort. Meanwhile, the TIW regimen offers a gentler option with fewer side effects, positioning it as a viable alternative for athletes concerned about nausea.
Read More
7
Ferric carboxymaltose reduces nausea
This randomized controlled trial explored how low-dose ferric carboxymaltose (FCM) affects hemoglobin levels and nausea in postpartum East Asian women. Participants received either an intravenous FCM infusion or oral iron for four weeks.
We found that while FCM significantly increased hemoglobin levels after two weeks, both treatments showed no significant difference in final hemoglobin results after four weeks.
Notably, the FCM group experienced fewer gastrointestinal side effects, including nausea, suggesting it may be a more comfortable option for new mothers.
We found that while FCM significantly increased hemoglobin levels after two weeks, both treatments showed no significant difference in final hemoglobin results after four weeks.
Notably, the FCM group experienced fewer gastrointestinal side effects, including nausea, suggesting it may be a more comfortable option for new mothers.
Read More
User Reviews
USERS' SCORE
Good
Based on 109 Reviews
8.6
- All Reviews
- Positive Reviews
- Negative Reviews
9.5
No nausea noted
A gentle and effective product. I've been using it every other day without any nausea, even on an empty stomach, and my iron levels improved!
Read More
9.5
No nausea experienced
I have dealt with iron deficiency anaemia my entire adult life. I usually maintain my iron levels through diet but turned to Solgar's Gentle Iron when my haemoglobin fell to critical levels. It has low toxicity and is well-absorbed, unlike other supplements that upset my stomach. After taking it, my dizziness and darkening vision when standing quickly improved. I experienced no nausea or pain for five months. I recommend taking iron at night, avoiding food before and after, and combining it with vitamin C.
Read More
0
Severe nausea
This product caused excruciating stomach cramps, diarrhoea, and severe nausea.
Read More
9.5
Nausea absent
I took this iron for seven days post-menstruation, and I no longer felt dizzy. I suggest testing for ferritin levels. I did not experience nausea or any side effects. I am satisfied, as I used to get cold easily, which is a sign of low iron.
Read More
9.5
No nausea noted
This is a wonderful iron supplement with high quality and easily digestible components that do not cause irritation or nausea. I felt better while using this product, and in consultation with my nutritionist, I took it alongside vitamin C to improve absorption. I highly recommend it.
Read More
Frequently Asked Questions
No FAQs are available for this product and symptom.
References
- Srivastav A, Kshirsagar S, Adhav T, Ganu G, Shah A. Efficacy and Safety of Microsomal Ferric Pyrophosphate Supplement for Iron Deficiency Anemia in Pregnancy. Cureus. 2024;16:e57108. doi:10.7759/cureus.57108
- Schulte J, Peterson K, Thomsen T, Lentz S, Hall M, et al. Daily versus three times weekly dosing for treatment of iron deficiency nonanemia in NCAA Division 1 female athletes. PM R. 2024;16:316. doi:10.1002/pmrj.13172
- Nagao T, Takahashi K, Takahashi S, Yokomizo R, Samura O, et al. Low-dose ferric carboxymaltose vs. oral iron for improving hemoglobin levels in postpartum East Asian women: A randomized controlled trial. PLoS One. 2025;20:e0319795. doi:10.1371/journal.pone.0319795
- Wada-Hiraike O, Maruyama A, Mitobe Y, Iriyama T, Mori-Uchino M, et al. A Multicenter Single-Arm Study of Switching to Ferric Citrate Hydrate for Iron Deficiency Anemia in Patients Intolerant to Oral Iron: RIO-SWITCH. Adv Ther. 2025. doi:10.1007/s12325-025-03123-9
