We investigated the role of ferroptosis in chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS). By using an experimental model, we applied treatments with deferoxamine (DFO) and edaravone (EDA) to inhibit ferroptosis.
Our findings revealed that targeting ferroptosis may reduce inflammation, fibrosis, and mast cell activity, potentially easing pelvic pain associated with CP/CPPS. These results highlight a new pathway for treating this challenging condition, offering hope for improved management strategies.
Read More
7
Long-acting contraceptives offer health benefits
Added health benefits of the levonorgestrel contraceptive intrauterine system and other hormonal contraceptive delivery systems.
We discovered that hormonal contraceptives, particularly long-acting systems like the levonorgestrel-releasing intrauterine device, provide significant non-contraceptive health benefits.
These benefits include the treatment of pelvic pain, especially in cases related to endometriosis, as well as management of heavy menstrual bleeding and iron deficiency.
Research highlights that these contraceptives are effective options for addressing various gynecological disorders beyond birth control.
Read More
5
Iron patch offers similar pain relief
Comparing the analgesic effect of heat patch containing iron chip and ibuprofen for primary dysmenorrhea: a randomized controlled trial.
We explored the effectiveness of a heat patch containing iron chips compared to ibuprofen for alleviating primary dysmenorrhea. In our randomized controlled trial involving 147 students, we examined pain severity and emotional impact using a standardized questionnaire.
Although we found that the heat patch provided comparable relief to ibuprofen, the differences in pain severity were not significant. This suggests that while the heat patch is a viable option, it may not be markedly more effective than ibuprofen for managing menstrual pain.
Read More
Most Useful Reviews
9
Reduced pelvic pain
10 people found this helpful
I suffered from menorrhagia due to uterine fibroids, taking iron and Chinese medicine, but stopped due to stomach pain, nausea, and constipation. I often experienced dizziness and vomiting during my periods. However, this iron supplement causes no stomach pain, making it comfortable, and I now wake up refreshed. I take one tablet daily before bed with vitamin C. I recommend it to those who’ve not felt the effects of other iron preparations.
Read More
0
No results
5 people found this helpful
I took this chelated iron for two months without any improvement; my ferritin only increased slightly. It caused gastrointestinal issues and discomfort. Upon stopping, my stomach returned to normal.
Read More
0
Worsened pelvic pain
3 people found this helpful
Unfortunately, this product did not work for me; it aggravated my situation, causing severe stomach pain, nausea, and weakness.
We investigated the role of ferroptosis in chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS). By using an experimental model, we applied treatments with deferoxamine (DFO) and edaravone (EDA) to inhibit ferroptosis.
Our findings revealed that targeting ferroptosis may reduce inflammation, fibrosis, and mast cell activity, potentially easing pelvic pain associated with CP/CPPS. These results highlight a new pathway for treating this challenging condition, offering hope for improved management strategies.
Read More
7
Long-acting contraceptives offer health benefits
Added health benefits of the levonorgestrel contraceptive intrauterine system and other hormonal contraceptive delivery systems.
We discovered that hormonal contraceptives, particularly long-acting systems like the levonorgestrel-releasing intrauterine device, provide significant non-contraceptive health benefits.
These benefits include the treatment of pelvic pain, especially in cases related to endometriosis, as well as management of heavy menstrual bleeding and iron deficiency.
Research highlights that these contraceptives are effective options for addressing various gynecological disorders beyond birth control.
Read More
7
Goserelin enhances hemoglobin but not pain
Goserelin acetate 10.8 mg plus iron versus iron monotherapy prior to surgery in premenopausal women with iron-deficiency anemia due to uterine leiomyomas: results from a Phase III, randomized, multicenter, double-blind, controlled trial.
We aimed to understand the impact of adding goserelin acetate to iron treatment in premenopausal women facing iron-deficiency anemia due to uterine fibroids.
In this Phase III trial, participants received either goserelin with iron or just iron over 12 weeks, followed by surgery. While women given goserelin showed higher hemoglobin levels, we didn’t find a significant improvement in symptoms like pelvic pain.
Overall, while goserelin helped with blood levels, it didn't make a noticeable difference in alleviating pelvic discomfort.
Read More
5
Lactoferrin benefits menstrual distress
Effects of a Bovine Lactoferrin Formulation from Cow's Milk on Menstrual Distress in Volunteers: A Randomized, Crossover Study.
Our study examined the effects of a lactoferrin formulation derived from cow's milk on menstrual symptoms in healthy women.
Conducted as a double-blind, randomized, placebo-controlled trial, we enrolled thirty-five Japanese volunteers who received either the iron-lactoferrin complex or a placebo.
While our findings showed improvements in psychological symptoms related to menstrual distress, such as reduced MDQ scores, other measures—like pain and quality of life—did not vary significantly.
Notably, no side effects were reported, suggesting this treatment could help with psychological discomfort linked to dysmenorrhea.
Read More
5
Iron patch offers similar pain relief
Comparing the analgesic effect of heat patch containing iron chip and ibuprofen for primary dysmenorrhea: a randomized controlled trial.
We explored the effectiveness of a heat patch containing iron chips compared to ibuprofen for alleviating primary dysmenorrhea. In our randomized controlled trial involving 147 students, we examined pain severity and emotional impact using a standardized questionnaire.
Although we found that the heat patch provided comparable relief to ibuprofen, the differences in pain severity were not significant. This suggests that while the heat patch is a viable option, it may not be markedly more effective than ibuprofen for managing menstrual pain.
Read More
User Reviews
USERS' SCORE
Questionable
Based on 17 Reviews
5.9
All Reviews
Positive Reviews
Negative Reviews
9
Reduced pelvic pain
10 people found this helpful
I suffered from menorrhagia due to uterine fibroids, taking iron and Chinese medicine, but stopped due to stomach pain, nausea, and constipation. I often experienced dizziness and vomiting during my periods. However, this iron supplement causes no stomach pain, making it comfortable, and I now wake up refreshed. I take one tablet daily before bed with vitamin C. I recommend it to those who’ve not felt the effects of other iron preparations.
Read More
0
No results
5 people found this helpful
I took this chelated iron for two months without any improvement; my ferritin only increased slightly. It caused gastrointestinal issues and discomfort. Upon stopping, my stomach returned to normal.
Read More
0
Worsened pelvic pain
3 people found this helpful
Unfortunately, this product did not work for me; it aggravated my situation, causing severe stomach pain, nausea, and weakness.
Read More
0
Severe pain
3 people found this helpful
The supplement caused severe stomach pain, which subsided immediately after I stopped taking it.
Read More
0
Abdominal swelling
3 people found this helpful
After two days of using this supplement instead of the prescribed iron, I experienced significant swelling and abdominal pain. I will not use it again.
Pelvic pain is a broad term that describes discomfort occurring in the lower abdomen or pelvic region. It can stem from various underlying conditions, involving reproductive organs, the urinary tract, or gastrointestinal issues. Common causes include menstrual cramps, endometriosis, pelvic inflammatory disease, ovarian cysts, and urinary tract infections. Additionally, pelvic pain can be acute, occurring suddenly and sharply, or chronic, lasting for six months or more, significantly impacting one’s quality of life.
Managing pelvic pain often begins with a thorough evaluation from a healthcare provider to determine the underlying causes. Treatment options can vary widely based on the diagnosis and may include medication for pain relief, physical therapy, lifestyle changes, or, in some cases, surgery. Lifestyle adjustments, such as heat therapy and relaxation techniques, can also provide relief. Given the diverse nature of pelvic pain, it’s essential for individuals experiencing persistent discomfort to consult a medical professional for an accurate diagnosis and personalized treatment plan.
Iron is a chemical element with the symbol Fe, derived from the Latin word "ferrum." It is a metal that is known for its strength and versatility, making it one of the most widely used materials in construction, manufacturing, and various industrial applications. Iron is the fourth most abundant element in the universe by mass and is primarily obtained through the mining of iron ores, such as hematite and magnetite. Once mined, it undergoes processes like smelting and refining to produce usable forms like cast iron, wrought iron, and steel.
In addition to its industrial uses, iron is also crucial for human health, as it plays a significant role in the production of hemoglobin, the protein in red blood cells responsible for transporting oxygen throughout the body. A deficiency in iron can lead to anemia, characterized by fatigue and weakened immunity. Overall, iron is a fundamental element that supports modern infrastructure and is vital for maintaining good health.
Based on user reviews, the timeline for seeing results from this supplement can vary significantly. Some users reported feeling positive effects within days. For instance, a user noted feeling wonderful after just five days of use, praising the supplement for being light and gentle with no painful side effects Read Review. Another reviewer indicated that after two weeks, they noticed changes in their stools and felt generally better Read Review.
However, not all experiences were positive, with some users experiencing discomfort or no noticeable improvement after extended periods of use. One user who took the supplement for two months only saw a slight increase in ferritin levels without any significant change in their condition Read Review. Overall, it seems that while some may feel relief quickly, others may need to wait weeks to gauge its effectiveness or could end up finding it unsuitable for their needs.
This supplement is partially supported by scientific research for pelvic pain, particularly in the context of chronic pelvic pain syndrome (CP/CPPS) and menstrual discomfort. A study found that targeting ferroptosis, a form of cell death, may help reduce inflammation and mast cell activity, which could ease pelvic pain linked to CP/CPPS [1]. This finding opens doors to new treatment avenues that may benefit those suffering from chronic pelvic pain.
Additionally, the role of hormonal contraceptives has been shown effective in treating pelvic pain related to endometriosis, highlighting a significant non-contraceptive benefit [3]. However, various other treatments, including lactoferrin and goserelin, did not exhibit substantial improvements in pelvic pain relief compared to their respective control groups, indicating that while there are options available, efficacy can vary [2][5]. Overall, while some research supports the use of certain supplements and treatments, their effectiveness can vary significantly, necessitating further investigation and individual assessment for those experiencing pelvic pain.
Based on user reviews, many individuals have reported significant improvements in their symptoms when using this iron supplement. For example, one user, who suffered from menorrhagia due to uterine fibroids, found that this supplement caused no stomach pain and allowed them to wake up feeling refreshed, recommending it to others who have not had success with other iron preparations Read Review. Several users noted reduced menstrual pain, with one reviewer stating that the supplement made their menstrual pain manageable for the first time Read Review. Meanwhile, another user cited a reduction in dizziness and headaches, marking a significant improvement in their overall well-being after using the product Read Review.
However, results can vary widely. There are several accounts of gastrointestinal distress, including stomach pain, nausea, and constipation that some users experienced while taking the supplement Read Review. Others reported severe discomfort, which led them to discontinue use Read Review. Overall, while many users appreciate the gentle formulation that appears to alleviate symptoms, others found it unsuitable due to adverse effects, highlighting that individual experiences with this supplement can differ significantly.
Based on user reviews, combining this iron supplement with vitamin C has been a common practice among users to enhance its effectiveness. One user specifically noted that taking the supplement with vitamin C helped improve their experience, as they had previously suffered from menorrhagia but found relief from stomach pain using this combination Read Review. Another user also mentioned following this practice and saw a notable change in their overall condition after a couple of weeks, despite initially experiencing some abdominal discomfort Read Review.
In contrast, some users reported adverse effects when combining this supplement with other practices or not adhering to specific guidelines. For example, another reviewer mentioned they faced severe stomach pain after two days of use, highlighting the importance of individual experiences when combining supplements Read Review. Overall, while many users found that pairing this iron supplement with vitamin C or taking it following specific guidelines was beneficial, others cautioned against potential gastrointestinal issues that could arise from improper use or individual sensitivity.
Based on user reviews, determining the right dose of iron for treating pelvic pain presents mixed experiences. Many users recommend taking one to two capsules daily, often paired with vitamin C to enhance absorption. For example, one user reported taking a single tablet daily before bed, which resulted in improved energy and reduced pain, without the gastrointestinal discomfort typically associated with iron supplements Read Review. Others echoed this sentiment, stating that they found a positive effect while taking two capsules a day, describing the iron as gentle and well-tolerated Read Review.
However, not all users had favorable experiences; some reported significant gastrointestinal issues at varying doses. A user mentioned their ferritin levels improved only slightly after two months on the supplement, while experiencing discomfort Read Review. Another user noted severe stomach pain after taking the supplement, highlighting the importance of finding a form of iron that suits one's body Read Review. Overall, while one to two capsules appear to be a common recommendation, individual tolerance varies greatly, suggesting that prospective users should consult healthcare providers for personalized dosages and forms of iron that best suit their needs.
9
Lightened pelvic pain
1 people found this helpful
After five days of use, I feel wonderful; it’s light and gentle compared to other types I've tried. Most importantly, there’s been no headache or abdominal pain. I will evaluate it further once the box is finished and go for an iron store test. I love the Solgar brand.
6
Gentle pelvic relief
1 people found this helpful
It's very gentle. I take two a day with vitamin C and follow all guidelines. Initially, I experienced some abdominal pain, but that quickly passed. By two weeks in, I noticed a change in my stools. I also felt sleepy after taking the capsules; overall, I find the effects on my gastrointestinal tract mild.
0
No results
5 people found this helpful
I took this chelated iron for two months without any improvement; my ferritin only increased slightly. It caused gastrointestinal issues and discomfort. Upon stopping, my stomach returned to normal.
9
Reduced pelvic pain
10 people found this helpful
I suffered from menorrhagia due to uterine fibroids, taking iron and Chinese medicine, but stopped due to stomach pain, nausea, and constipation. I often experienced dizziness and vomiting during my periods. However, this iron supplement causes no stomach pain, making it comfortable, and I now wake up refreshed. I take one tablet daily before bed with vitamin C. I recommend it to those who’ve not felt the effects of other iron preparations.
7.5
Improved pelvic pain
2 people found this helpful
I've dealt with “anemia” since I was young, but didn’t treat it until my mid-thirties and faced tough menstrual pain. I’ve been using this supplement for about three weeks, and unlike Japanese iron, it hasn’t caused constipation or illness. My menstrual pain has remarkably improved; it’s manageable now, and I intend to keep using it.
7.5
Addressed pelvic pain
1 people found this helpful
After experiencing debilitating dizziness, fatigue, and severe abdominal pain during my last menstrual periods, a doctor advised iron supplementation. This product surprisingly has no unpleasant smells and I've felt my dizziness and headaches dissipate after taking it. Important advice: reduce coffee and tea intake while on iron supplements to enhance absorption!
0
Severe stomach pain
This supplement caused terrible stomach pains and dried my lips. There's no need to take it if blood tests show no vitamin deficiency; one carrot can provide enough. It’s highly advised for smokers to avoid this supplement. I stopped after just two days.
0
Abdominal swelling
3 people found this helpful
After two days of using this supplement instead of the prescribed iron, I experienced significant swelling and abdominal pain. I will not use it again.
0
Constipation and pain
This supplement led to constipation and stomach pain, leaving me disappointed. It did not help my condition at all.
7
Ferroptosis inhibition for pelvic pain
Targeting Ferroptosis Attenuates Inflammation, Fibrosis, and Mast Cell Activation in Chronic Prostatitis.
We investigated the role of ferroptosis in chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS). By using an experimental model, we applied treatments with deferoxamine (DFO) and edaravone (EDA) to inhibit ferroptosis.
Our findings revealed that targeting ferroptosis may reduce inflammation, fibrosis, and mast cell activity, potentially easing pelvic pain associated with CP/CPPS. These results highlight a new pathway for treating this challenging condition, offering hope for improved management strategies.
7
Long-acting contraceptives offer health benefits
Added health benefits of the levonorgestrel contraceptive intrauterine system and other hormonal contraceptive delivery systems.
We discovered that hormonal contraceptives, particularly long-acting systems like the levonorgestrel-releasing intrauterine device, provide significant non-contraceptive health benefits.
These benefits include the treatment of pelvic pain, especially in cases related to endometriosis, as well as management of heavy menstrual bleeding and iron deficiency.
Research highlights that these contraceptives are effective options for addressing various gynecological disorders beyond birth control.
5
Lactoferrin benefits menstrual distress
Effects of a Bovine Lactoferrin Formulation from Cow's Milk on Menstrual Distress in Volunteers: A Randomized, Crossover Study.
Our study examined the effects of a lactoferrin formulation derived from cow's milk on menstrual symptoms in healthy women.
Conducted as a double-blind, randomized, placebo-controlled trial, we enrolled thirty-five Japanese volunteers who received either the iron-lactoferrin complex or a placebo.
While our findings showed improvements in psychological symptoms related to menstrual distress, such as reduced MDQ scores, other measures—like pain and quality of life—did not vary significantly.
Notably, no side effects were reported, suggesting this treatment could help with psychological discomfort linked to dysmenorrhea.
7
Goserelin enhances hemoglobin but not pain
Goserelin acetate 10.8 mg plus iron versus iron monotherapy prior to surgery in premenopausal women with iron-deficiency anemia due to uterine leiomyomas: results from a Phase III, randomized, multicenter, double-blind, controlled trial.
We aimed to understand the impact of adding goserelin acetate to iron treatment in premenopausal women facing iron-deficiency anemia due to uterine fibroids.
In this Phase III trial, participants received either goserelin with iron or just iron over 12 weeks, followed by surgery. While women given goserelin showed higher hemoglobin levels, we didn’t find a significant improvement in symptoms like pelvic pain.
Overall, while goserelin helped with blood levels, it didn't make a noticeable difference in alleviating pelvic discomfort.
References
Lin D, Zhang M, Luo C, Wei P, Cui K, et al. Targeting Ferroptosis Attenuates Inflammation, Fibrosis, and Mast Cell Activation in Chronic Prostatitis. J Immunol Res. 2022;2022:6833867. doi:10.1155/2022/6833867
Ueno HM, Yoshise RE, Sugino T, Kajimoto O, Kobayashi T. Effects of a Bovine Lactoferrin Formulation from Cow's Milk on Menstrual Distress in Volunteers: A Randomized, Crossover Study. Int J Mol Sci. 2016;17. doi:10.3390/ijms17060845
Fraser IS. Added health benefits of the levonorgestrel contraceptive intrauterine system and other hormonal contraceptive delivery systems. Contraception. 2013;87:273. doi:10.1016/j.contraception.2012.08.039
Navvabi Rigi S, Kermansaravi F, Navidian A, Safabakhsh L, Safarzadeh A, et al. Comparing the analgesic effect of heat patch containing iron chip and ibuprofen for primary dysmenorrhea: a randomized controlled trial. BMC Womens Health. 2012;12:25. doi:10.1186/1472-6874-12-25
Muneyyirci-Delale O, Richard-Davis G, Morris T, Armstrong J. Goserelin acetate 10.8 mg plus iron versus iron monotherapy prior to surgery in premenopausal women with iron-deficiency anemia due to uterine leiomyomas: results from a Phase III, randomized, multicenter, double-blind, controlled trial. Clin Ther. 2007;29:1682.