Overview

SCIENTIFIC SCORE
Possibly Effective
Based on 4 Researches
7
USERS' SCORE
Good
Based on 14 Reviews
8.3
Supplement Facts
Serving Size: 5 Tablets
Amount Per Serving
%DV
Vitamin D3 (as cholecalciferol)
10 mcg (400 IU)
50%
Calcium (as calcium citrate)
1,000 mg
77%
Magnesium (as magnesium oxide, magnesium citrate)
500 mg
119%
Sodium
20 mg
<1%

Top Medical Research Studies

We set out to evaluate what effect vitamin D3 supplementation might have on patients suffering from mild obstructive sleep apnea syndrome (OSAS). In this study, 19 adult men who were diagnosed with mild OSAS and had low vitamin D levels participated over an 8-week period. Each week, they took a sizable dose of 50,000 IU of vitamin D3 while undergoing various health assessments. We measured important factors like blood glucose, lipid profiles, and inflammation markers, along with repeated sleep monitoring through polysomnography.

By the end of the study, we observed a significant increase in participants' vitamin D levels, which jumped from an average of 19.5 to 41.8 ng/mL—an indication that the supplementation was effective. Along with this rise in vitamin D, we also noted improvements in fasting blood glucose and total cholesterol levels, as well as a decrease in key inflammation markers. Most encouragingly, the frequency of obstructive apneas and other related sleep disturbances significantly decreased.

Based on these findings, it seems that vitamin D supplementation can play a beneficial role in improving the prognosis for those with mild OSAS. It's exciting to consider how something as simple as a vitamin could lead to better sleep health for individuals struggling with sleep apnea.
Read More
4
Vitamin D3 enhances metabolic health
We conducted a pilot study to see how vitamin D3 supplementation impacts individuals with obstructive sleep apnea (OSA). Our double-blind, randomized, placebo-controlled trial involved 19 Caucasian adults with OSA, some of whom were already using continuous positive airways pressure (CPAP) therapy.

Over a 15-week period, participants took either 4,000 IU of vitamin D3 or a placebo. We assessed various outcomes, including drowsiness, quality of life, fatigue levels, and cognitive function. While we observed a significant increase in vitamin D levels among those who received the supplement, we found that it did not improve symptoms related to sleepiness, quality of life, or cognitive performance.

Interestingly, we did notice a decrease in certain metabolic markers, suggesting that vitamin D3 may play a role in improving metabolic health among OSA patients. Overall, while vitamin D3 showed promise in enhancing metabolic parameters, it didn’t seem to alleviate the primary symptoms of OSA. Our findings pave the way for larger studies to further explore these effects.
Read More
7
Magnesium's role in sleep apnea
We aimed to uncover the relationship between magnesium levels and sleep quality, particularly focusing on sleep apnea. Our study analyzed data from a large group of adults aged 20 and older, using a well-structured method to assess magnesium levels and the prevalence of sleep issues.

We found a notable connection between lower magnesium levels, measured as the magnesium depletion score (MDS), and the likelihood of experiencing sleep apnea. Specifically, individuals with higher MDS levels were significantly more likely to report sleep apnea, showing over three times the odds compared to those with adequate magnesium levels.

Interestingly, our research did not link magnesium deficiency to other sleep problems like insomnia or restless legs syndrome, suggesting a more complex relationship with sleep apnea alone. Additionally, we noticed that older adults with depressive symptoms showed a tendency toward excessive sleep rather than insufficient sleep.

While our findings highlight the association between magnesium deficiency and sleep apnea, they also point towards the potential of adequate magnesium intake in reducing this risk. This emphasizes the importance of maintaining proper magnesium levels for better sleep quality, especially in those at higher risk for sleep apnea.
Read More

Most Useful Reviews

8
Calm sleep achieved
4 people found this helpful
I find Magnesium B6 provides sound sleep and a sense of calm that feels comforting.
Read More
9
Improved sleep quality
1 people found this helpful
My mum had a problem with sleep, and this medication helped me to achieve a good night's rest by the third day of taking it. It took about half a year to see similar results again.
Read More
9
Improved sleep
Thanks to this, I sleep. Very good.
Read More

Medical Researches

SCIENTIFIC SCORE
Possibly Effective
Based on 4 Researches
7
  • All Researches
We set out to evaluate what effect vitamin D3 supplementation might have on patients suffering from mild obstructive sleep apnea syndrome (OSAS). In this study, 19 adult men who were diagnosed with mild OSAS and had low vitamin D levels participated over an 8-week period. Each week, they took a sizable dose of 50,000 IU of vitamin D3 while undergoing various health assessments. We measured important factors like blood glucose, lipid profiles, and inflammation markers, along with repeated sleep monitoring through polysomnography.

By the end of the study, we observed a significant increase in participants' vitamin D levels, which jumped from an average of 19.5 to 41.8 ng/mL—an indication that the supplementation was effective. Along with this rise in vitamin D, we also noted improvements in fasting blood glucose and total cholesterol levels, as well as a decrease in key inflammation markers. Most encouragingly, the frequency of obstructive apneas and other related sleep disturbances significantly decreased.

Based on these findings, it seems that vitamin D supplementation can play a beneficial role in improving the prognosis for those with mild OSAS. It's exciting to consider how something as simple as a vitamin could lead to better sleep health for individuals struggling with sleep apnea.
Read More
8
Vitamin D linked to sleep apnea severity
We aimed to explore the connection between serum vitamin D levels and the severity of obstructive sleep apnea syndrome (OSAS), particularly in patients also dealing with metabolic syndrome, known as Syndrome Z. Our study involved 270 individuals diagnosed with both conditions. We gathered important data on various aspects, including demographics, sleep patterns, and laboratory results.

From our findings, we observed that a significant number of participants had varying degrees of OSAS severity. Notably, there was a clear trend showing that as the severity of OSAS increased, vitamin D levels decreased. After accounting for various factors, we found a strong association between lower serum 25(OH)D3 levels and greater OSAS severity.

This suggests that monitoring vitamin D levels in patients with the dual challenges of metabolic syndrome and sleep apnea could be vital. While our study highlights an association, we noted it does not directly address the effectiveness of vitamin D3 treatment for improving sleep apnea. Therefore, further research is needed to determine whether boosting vitamin D levels can positively impact sleep apnea symptoms.
Read More
7
Magnesium's role in sleep apnea
We aimed to uncover the relationship between magnesium levels and sleep quality, particularly focusing on sleep apnea. Our study analyzed data from a large group of adults aged 20 and older, using a well-structured method to assess magnesium levels and the prevalence of sleep issues.

We found a notable connection between lower magnesium levels, measured as the magnesium depletion score (MDS), and the likelihood of experiencing sleep apnea. Specifically, individuals with higher MDS levels were significantly more likely to report sleep apnea, showing over three times the odds compared to those with adequate magnesium levels.

Interestingly, our research did not link magnesium deficiency to other sleep problems like insomnia or restless legs syndrome, suggesting a more complex relationship with sleep apnea alone. Additionally, we noticed that older adults with depressive symptoms showed a tendency toward excessive sleep rather than insufficient sleep.

While our findings highlight the association between magnesium deficiency and sleep apnea, they also point towards the potential of adequate magnesium intake in reducing this risk. This emphasizes the importance of maintaining proper magnesium levels for better sleep quality, especially in those at higher risk for sleep apnea.
Read More
4
Vitamin D3 enhances metabolic health
We conducted a pilot study to see how vitamin D3 supplementation impacts individuals with obstructive sleep apnea (OSA). Our double-blind, randomized, placebo-controlled trial involved 19 Caucasian adults with OSA, some of whom were already using continuous positive airways pressure (CPAP) therapy.

Over a 15-week period, participants took either 4,000 IU of vitamin D3 or a placebo. We assessed various outcomes, including drowsiness, quality of life, fatigue levels, and cognitive function. While we observed a significant increase in vitamin D levels among those who received the supplement, we found that it did not improve symptoms related to sleepiness, quality of life, or cognitive performance.

Interestingly, we did notice a decrease in certain metabolic markers, suggesting that vitamin D3 may play a role in improving metabolic health among OSA patients. Overall, while vitamin D3 showed promise in enhancing metabolic parameters, it didn’t seem to alleviate the primary symptoms of OSA. Our findings pave the way for larger studies to further explore these effects.
Read More

User Reviews

USERS' SCORE
Good
Based on 14 Reviews
8.3
  • All Reviews
  • Positive Reviews
  • Negative Reviews
8
Calm sleep achieved
4 people found this helpful
I find Magnesium B6 provides sound sleep and a sense of calm that feels comforting.
Read More
9
Improved sleep quality
1 people found this helpful
My mum had a problem with sleep, and this medication helped me to achieve a good night's rest by the third day of taking it. It took about half a year to see similar results again.
Read More
9
Improved sleep
Thanks to this, I sleep. Very good.
Read More
9
Promotes restful sleep
I'm taking magnesium and enjoying a good night's sleep. Very satisfied with the results.
Read More
9
Job done well
1 people found this helpful
This is a good sleeping pill. Best Calcium. I truly enjoyed taking this at night; magnesium does its job effectively.
Read More

Frequently Asked Questions

9
Improved sleep quality
1 people found this helpful
My mum had a problem with sleep, and this medication helped me to achieve a good night's rest by the third day of taking it. It took about half a year to see similar results again.
8
Calm sleep achieved
4 people found this helpful
I find Magnesium B6 provides sound sleep and a sense of calm that feels comforting.
9
Promotes restful sleep
I'm taking magnesium and enjoying a good night's sleep. Very satisfied with the results.
7.5
Positive changes
I take these vitamins consistently and have noticed positive changes. Their quality is evident, and they are convenient to swallow. After starting magnesium with vitamin D3, my sleep improved, and joint pain has subsided.
7.5
Deep sleep
3 people found this helpful
Initially, I had eyelid twitches and turned to magnesium. While the twitches reduced, they didn’t entirely disappear until I switched to a more affordable option. Now, my sleep has deepened, and I feel rested. I plan to continue this routine.
7.5
Satisfactory delivery
The delivery was swift, and I am genuinely satisfied! Since it contains both calcium and magnesium, taking it together certainly enhances my sleep quality and alleviates muscle stiffness.
7.5
Better sleep overall
This has a great effect; taking it in the evening before bed significantly helps improve my sleep.
9
Reduced sleep disturbance
I bought this due to the twitching under my eyes, and using it results in much better sleep with fewer dreams at night.
8
Vitamin D linked to sleep apnea severity
We aimed to explore the connection between serum vitamin D levels and the severity of obstructive sleep apnea syndrome (OSAS), particularly in patients also dealing with metabolic syndrome, known as Syndrome Z. Our study involved 270 individuals diagnosed with both conditions. We gathered important data on various aspects, including demographics, sleep patterns, and laboratory results.

From our findings, we observed that a significant number of participants had varying degrees of OSAS severity. Notably, there was a clear trend showing that as the severity of OSAS increased, vitamin D levels decreased. After accounting for various factors, we found a strong association between lower serum 25(OH)D3 levels and greater OSAS severity.

This suggests that monitoring vitamin D levels in patients with the dual challenges of metabolic syndrome and sleep apnea could be vital. While our study highlights an association, we noted it does not directly address the effectiveness of vitamin D3 treatment for improving sleep apnea. Therefore, further research is needed to determine whether boosting vitamin D levels can positively impact sleep apnea symptoms.
We set out to evaluate what effect vitamin D3 supplementation might have on patients suffering from mild obstructive sleep apnea syndrome (OSAS). In this study, 19 adult men who were diagnosed with mild OSAS and had low vitamin D levels participated over an 8-week period. Each week, they took a sizable dose of 50,000 IU of vitamin D3 while undergoing various health assessments. We measured important factors like blood glucose, lipid profiles, and inflammation markers, along with repeated sleep monitoring through polysomnography.

By the end of the study, we observed a significant increase in participants' vitamin D levels, which jumped from an average of 19.5 to 41.8 ng/mL—an indication that the supplementation was effective. Along with this rise in vitamin D, we also noted improvements in fasting blood glucose and total cholesterol levels, as well as a decrease in key inflammation markers. Most encouragingly, the frequency of obstructive apneas and other related sleep disturbances significantly decreased.

Based on these findings, it seems that vitamin D supplementation can play a beneficial role in improving the prognosis for those with mild OSAS. It's exciting to consider how something as simple as a vitamin could lead to better sleep health for individuals struggling with sleep apnea.
7
Magnesium's role in sleep apnea
We aimed to uncover the relationship between magnesium levels and sleep quality, particularly focusing on sleep apnea. Our study analyzed data from a large group of adults aged 20 and older, using a well-structured method to assess magnesium levels and the prevalence of sleep issues.

We found a notable connection between lower magnesium levels, measured as the magnesium depletion score (MDS), and the likelihood of experiencing sleep apnea. Specifically, individuals with higher MDS levels were significantly more likely to report sleep apnea, showing over three times the odds compared to those with adequate magnesium levels.

Interestingly, our research did not link magnesium deficiency to other sleep problems like insomnia or restless legs syndrome, suggesting a more complex relationship with sleep apnea alone. Additionally, we noticed that older adults with depressive symptoms showed a tendency toward excessive sleep rather than insufficient sleep.

While our findings highlight the association between magnesium deficiency and sleep apnea, they also point towards the potential of adequate magnesium intake in reducing this risk. This emphasizes the importance of maintaining proper magnesium levels for better sleep quality, especially in those at higher risk for sleep apnea.

References

  1. Kilavuz A, Celikhisar H, Dasdemir Ilkhan G. The Association of Serum 25(OH) Vitamin D Level with Severity of Obstructive Sleep Apnea Syndrome in Patients with Syndrome Z (the Interaction of Obstructive Sleep Apnea with Metabolic Syndrome). Metab Syndr Relat Disord. 2021;19:549. 10.1089/met.2021.0066
  2. Ayyıldız F, Yıldıran H, Afandiyeva N, Gülbahar Ö, Köktürk O. The effects of vitamin D supplemantation on prognosis in patients with mild obstructive sleep apnea syndrome. Turk J Med Sci. 2021;51:2524. 10.3906/sag-2101-83
  3. Kerley CP, Hutchinson K, Bramham J, McGowan A, Faul J, et al. Vitamin D Improves Selected Metabolic Parameters but Not Neuropsychological or Quality of Life Indices in OSA: A Pilot Study. J Clin Sleep Med. 2017;13:19. 10.5664/jcsm.6378
  4. Luo X, Tang M, Wei X, Peng Y. Association between magnesium deficiency score and sleep quality in adults: A population-based cross-sectional study. J Affect Disord. 2024;358:105. 10.1016/j.jad.2024.05.002
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