Overview

SCIENTIFIC SCORE
Moderately Effective
Based on 2 Researches
8
USERS' SCORE
Excellent
Based on 352 Reviews
9
Supplement Facts
Serving Size: 1 Tablet
Amount Per Serving
%DV
Calories
5
 
Total Carbohydrate
1 g
<1%**
Vitamin C(as Ester C® calcium ascorbate)
1,000 mg
1,111%
Calcium(as Ester-C® calcium ascorbate)
100 mg
8%
Citrus BioflavonoidComplex
200 mg
***
Acerola Extract
25 mg
***
Rose Hips (fruit)
25 mg
***
Rutin
25 mg
***

Top Medical Research Studies

7
Effectiveness of Vitamin C on Colds
We explored the effects of vitamin C on the common cold and pneumonia by examining a range of studies. Interestingly, research on animals suggests that vitamin C may have protective effects against infections. However, when it comes to preventing colds in the general population, taking more than 1 gram of vitamin C per day didn’t show significant benefits.

But there's a twist! Participants engaged in heavy physical activities saw their cold incidence reduced by half with vitamin C supplementation. Additionally, regular intake of 1 gram or more daily was linked to a 15% decrease in cold severity. While some therapeutic trials showed inconsistent results when vitamin C was taken after cold symptoms appeared, two studies did indicate that larger doses (6-8 grams per day) could effectively shorten the duration of colds compared to lower doses.

Our investigation also looked into pneumonia, but the studies were conducted in unique settings, such as a boarding school and military recruits. This makes it hard to generalize the findings to the wider population. Yet, some trials suggested benefits for pneumonia patients. Finally, the role of vitamin C in treating COVID-19 and sepsis remains unclear, with mixed results.

Given that vitamin C seems to alleviate symptoms and shorten the duration of colds, while being safe and affordable, it might be worth considering a dose of 6-8 grams per day to see if it helps at an individual level.
Read More
9
Vitamin C improves cold tolerance
We explored the effects of ascorbic acid, commonly known as vitamin C, on cold tolerance in tomato seedlings. In our study, we discovered that applying vitamin C significantly boosts the seedlings' ability to handle cold stress.

By enhancing the antioxidant defense system, vitamin C treatment increased the enzyme activity in the seedlings' leaves. Additionally, it raised levels of important compounds such as proline, sugar, and abscisic acid, all of which play crucial roles in plant stress responses.

Our observations showed that vitamin C also protects the photosynthesis system of tomato seedlings. This implies that it helps maintain chlorophyll function, which is critical for the plant's overall health, especially under cold conditions.

Moreover, we found that vitamin C treatments led to increased expression of genes linked to antioxidant enzymes and cold response mechanisms. Overall, our findings suggest that exogenous vitamin C is a beneficial approach to improve cold tolerance in tomatoes and may provide helpful insights for farmers looking to cultivate hardier varieties during colder months.
Read More

Most Useful Reviews

9.5
Effective against cold
In the season of colds, I take one daily. I forgot about the cold and, interestingly, herpes has also disappeared. The only downside is that the tablets are quite large and hard to swallow. I split them and drink them.
Read More
9.5
No more colds
I'm sold on Ester C for two reasons: myself and my dog. I've taken Ester-C for 15 years and have had no colds or sore throats since. My Bichon, previously prone to bladder issues, also benefits from it. There have been no bloody urine incidents since she started on Ester-C. The vet notes she still has crystals, but I'm grateful there’s no blood.
Read More
10
Immediate relief from cold
ASSISTANT IN THE FIRST SIGNS OF A COLD! This Vitamin C works 100%. As soon as I sense I'm about to get ill, I take two tablets immediately. The discomfort disappears as if by magic!
Read More

Medical Researches

SCIENTIFIC SCORE
Moderately Effective
Based on 2 Researches
8
  • All Researches
9
Vitamin C improves cold tolerance
We explored the effects of ascorbic acid, commonly known as vitamin C, on cold tolerance in tomato seedlings. In our study, we discovered that applying vitamin C significantly boosts the seedlings' ability to handle cold stress.

By enhancing the antioxidant defense system, vitamin C treatment increased the enzyme activity in the seedlings' leaves. Additionally, it raised levels of important compounds such as proline, sugar, and abscisic acid, all of which play crucial roles in plant stress responses.

Our observations showed that vitamin C also protects the photosynthesis system of tomato seedlings. This implies that it helps maintain chlorophyll function, which is critical for the plant's overall health, especially under cold conditions.

Moreover, we found that vitamin C treatments led to increased expression of genes linked to antioxidant enzymes and cold response mechanisms. Overall, our findings suggest that exogenous vitamin C is a beneficial approach to improve cold tolerance in tomatoes and may provide helpful insights for farmers looking to cultivate hardier varieties during colder months.
Read More
7
Effectiveness of Vitamin C on Colds
We explored the effects of vitamin C on the common cold and pneumonia by examining a range of studies. Interestingly, research on animals suggests that vitamin C may have protective effects against infections. However, when it comes to preventing colds in the general population, taking more than 1 gram of vitamin C per day didn’t show significant benefits.

But there's a twist! Participants engaged in heavy physical activities saw their cold incidence reduced by half with vitamin C supplementation. Additionally, regular intake of 1 gram or more daily was linked to a 15% decrease in cold severity. While some therapeutic trials showed inconsistent results when vitamin C was taken after cold symptoms appeared, two studies did indicate that larger doses (6-8 grams per day) could effectively shorten the duration of colds compared to lower doses.

Our investigation also looked into pneumonia, but the studies were conducted in unique settings, such as a boarding school and military recruits. This makes it hard to generalize the findings to the wider population. Yet, some trials suggested benefits for pneumonia patients. Finally, the role of vitamin C in treating COVID-19 and sepsis remains unclear, with mixed results.

Given that vitamin C seems to alleviate symptoms and shorten the duration of colds, while being safe and affordable, it might be worth considering a dose of 6-8 grams per day to see if it helps at an individual level.
Read More

User Reviews

USERS' SCORE
Excellent
Based on 352 Reviews
9
  • All Reviews
  • Positive Reviews
  • Negative Reviews
9.5
Effective against cold
In the season of colds, I take one daily. I forgot about the cold and, interestingly, herpes has also disappeared. The only downside is that the tablets are quite large and hard to swallow. I split them and drink them.
Read More
9.5
No more colds
I'm sold on Ester C for two reasons: myself and my dog. I've taken Ester-C for 15 years and have had no colds or sore throats since. My Bichon, previously prone to bladder issues, also benefits from it. There have been no bloody urine incidents since she started on Ester-C. The vet notes she still has crystals, but I'm grateful there’s no blood.
Read More
10
Immediate relief from cold
ASSISTANT IN THE FIRST SIGNS OF A COLD! This Vitamin C works 100%. As soon as I sense I'm about to get ill, I take two tablets immediately. The discomfort disappears as if by magic!
Read More
9.5
Combat cold effectively
Huge benefit to health! I take two pieces daily and have completely rid myself of catarrhal illnesses. Despite struggling with colds for nearly 60 years, I strongly recommend everyone try it.
Read More
9.5
Convenient to take
The best! Definitely to take! This has been a lifesaver during the cold season; it's so convenient to drink just once a day. I always take it.
Read More

Frequently Asked Questions

No FAQs are available for this product and symptom.

References

  1. Hemilä H, Chalker E. Vitamin C for the common cold and pneumonia. Pol Arch Intern Med. 2025;135. doi:10.20452/pamw.16926
  2. Wang X, Ran C, Fu Y, Han L, Yang X, et al. Application of Exogenous Ascorbic Acid Enhances Cold Tolerance in Tomato Seedlings through Molecular and Physiological Responses. Int J Mol Sci. 2024;25. doi:10.3390/ijms251810093
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