Overview
SCIENTIFIC SCORE
Moderately Effective
Based on 5 Researches
8
USERS' SCORE
Medium or Average
Based on 10 Reviews
6.2
Supplement Facts
Serving Size: 1 Softgel
Amount Per Serving
%DV
Calories
15
Total Fat
1.5 g
2%**
Polyunsaturated Fat
1 g
***
Evening Primrose Oil (Seed) providing:
1300 mg
***
Linoleic Acid
949 mg
***
Gamma-Linolenic Acid
117 mg
***
Top Medical Research Studies
9
We explored how evening primrose oil might affect blood clotting in rabbits fed a high-cholesterol diet. Using a group of 40 rabbits, we supplemented their diet for 6 weeks with evening primrose oil.
The results showed promising anti-thrombotic effects. Evening primrose oil reduced cholesterol levels and improved good HDL cholesterol. Additionally, it lessened platelet adhesion to the endothelium and decreased signs of vascular damage.
Overall, we found that this dietary supplement can enhance endothelial health and may help reduce clot formation.
The results showed promising anti-thrombotic effects. Evening primrose oil reduced cholesterol levels and improved good HDL cholesterol. Additionally, it lessened platelet adhesion to the endothelium and decreased signs of vascular damage.
Overall, we found that this dietary supplement can enhance endothelial health and may help reduce clot formation.
8
Evening primrose oil reduces clotting risk
We investigated how evening primrose oil (EPO) influences blood clotting when paired with celecoxib, a medication linked to thrombotic events. Using a mouse model, we administered celecoxib alongside EPO or forskolin for four weeks, followed by a prothrombotic challenge.
Our findings suggest that while celecoxib increased thrombotic markers, the addition of EPO significantly reduced this prothrombotic effect. This indicates that EPO may help offset some negative cardiovascular impacts of celecoxib, proving its potential in clinical use.
Our findings suggest that while celecoxib increased thrombotic markers, the addition of EPO significantly reduced this prothrombotic effect. This indicates that EPO may help offset some negative cardiovascular impacts of celecoxib, proving its potential in clinical use.
8
We examined the effects of evening primrose oil (EPO) on blood platelet aggregation, a key factor in blood clot formation. Over six weeks, 40 male rabbits were divided into groups and fed either a normal diet or an atherogenic diet, with some receiving EPO.
The atherogenic diet increased platelet aggregation significantly. However, EPO supplementation notably reduced this hyperaggregation to normal levels. Additionally, it helped lower thromboxane levels and lipid peroxides, which are markers linked to clotting issues.
Overall, these findings suggest that EPO may offer protective benefits against excessive blood clotting in diets high in unhealthy fats.
The atherogenic diet increased platelet aggregation significantly. However, EPO supplementation notably reduced this hyperaggregation to normal levels. Additionally, it helped lower thromboxane levels and lipid peroxides, which are markers linked to clotting issues.
Overall, these findings suggest that EPO may offer protective benefits against excessive blood clotting in diets high in unhealthy fats.
Most Useful Reviews
9
Improved menstrual cycle
5 people found this helpful
My experience with evening primrose oil began after struggling with endometriosis and blood clots. After two months of taking it, my cycle normalised, and the fibroids ceased to be palpable. My skin completely transformed; it is now soft, smooth, and clear. I did have an initial detox period with acne, but ultimately, evening primrose oil significantly alleviated my conditions, including the pain from endometriosis and heavy periods, improving my overall well-being.
2
Pain relief and bleeding
6 people found this helpful
Evening primrose oil relieved pain from endometriosis, but thinning the blood led to heavier menstruation. It’s a double-edged sword; while the pain was alleviated, the increased blood flow during menstruation was concerning.
7.5
Eased menstrual symptoms
1 people found this helpful
I began taking Solgar Evening Primrose Oil as my gynecologist suggested it for relieving menstrual pain. I noticed a significant reduction in irritability and menstrual discomfort right from the start. The heaviness and blood clots also decreased, leading to a more manageable cycle. Additionally, my skin became smoother, improving its overall condition. It is beneficial for women's health overall.
Medical Researches
SCIENTIFIC SCORE
Moderately Effective
Based on 5 Researches
8
- All Researches
9
We explored how evening primrose oil might affect blood clotting in rabbits fed a high-cholesterol diet. Using a group of 40 rabbits, we supplemented their diet for 6 weeks with evening primrose oil.
The results showed promising anti-thrombotic effects. Evening primrose oil reduced cholesterol levels and improved good HDL cholesterol. Additionally, it lessened platelet adhesion to the endothelium and decreased signs of vascular damage.
Overall, we found that this dietary supplement can enhance endothelial health and may help reduce clot formation.
The results showed promising anti-thrombotic effects. Evening primrose oil reduced cholesterol levels and improved good HDL cholesterol. Additionally, it lessened platelet adhesion to the endothelium and decreased signs of vascular damage.
Overall, we found that this dietary supplement can enhance endothelial health and may help reduce clot formation.
8
Evening primrose oil reduces clotting risk
We investigated how evening primrose oil (EPO) influences blood clotting when paired with celecoxib, a medication linked to thrombotic events. Using a mouse model, we administered celecoxib alongside EPO or forskolin for four weeks, followed by a prothrombotic challenge.
Our findings suggest that while celecoxib increased thrombotic markers, the addition of EPO significantly reduced this prothrombotic effect. This indicates that EPO may help offset some negative cardiovascular impacts of celecoxib, proving its potential in clinical use.
Our findings suggest that while celecoxib increased thrombotic markers, the addition of EPO significantly reduced this prothrombotic effect. This indicates that EPO may help offset some negative cardiovascular impacts of celecoxib, proving its potential in clinical use.
8
We investigated how evening primrose oil (EPO) affects blood clotting and blood pressure fluctuations caused by celecoxib in rats. Our study showed that celecoxib raised blood pressure and sped up blood clotting by increasing platelet activity. While EPO helped lower blood pressure and reduced platelet aggregation, omega-3 fatty acids did not have the same effect. This suggests EPO could be a helpful supplement to mitigate cardiovascular risks linked to celecoxib treatment.
8
We examined the effects of evening primrose oil (EPO) on blood platelet aggregation, a key factor in blood clot formation. Over six weeks, 40 male rabbits were divided into groups and fed either a normal diet or an atherogenic diet, with some receiving EPO.
The atherogenic diet increased platelet aggregation significantly. However, EPO supplementation notably reduced this hyperaggregation to normal levels. Additionally, it helped lower thromboxane levels and lipid peroxides, which are markers linked to clotting issues.
Overall, these findings suggest that EPO may offer protective benefits against excessive blood clotting in diets high in unhealthy fats.
The atherogenic diet increased platelet aggregation significantly. However, EPO supplementation notably reduced this hyperaggregation to normal levels. Additionally, it helped lower thromboxane levels and lipid peroxides, which are markers linked to clotting issues.
Overall, these findings suggest that EPO may offer protective benefits against excessive blood clotting in diets high in unhealthy fats.
7
Evening primrose oil shows limited effectiveness
We explored the impact of evening primrose oil (EPO) on patients with Raynaud's phenomenon (RP) by conducting a double-blind study. Initially, 21 participants received a two-week placebo course. Following this, 11 patients were given EPO for eight weeks while 10 continued with placebo. Overall, those on EPO reported fewer attacks during colder weather and reported improvements in symptoms.
However, objective measures like hand temperatures and blood flow tests didn't show significant improvement. While there were some observed antiplatelet effects and changes in platelet behavior, the treatment did not lead to marked changes in blood clotting relevant to blood flow improvement.
However, objective measures like hand temperatures and blood flow tests didn't show significant improvement. While there were some observed antiplatelet effects and changes in platelet behavior, the treatment did not lead to marked changes in blood clotting relevant to blood flow improvement.
User Reviews
USERS' SCORE
Medium or Average
Based on 10 Reviews
6.2
- All Reviews
- Positive Reviews
- Negative Reviews
9
Improved menstrual cycle
5 people found this helpful
My experience with evening primrose oil began after struggling with endometriosis and blood clots. After two months of taking it, my cycle normalised, and the fibroids ceased to be palpable. My skin completely transformed; it is now soft, smooth, and clear. I did have an initial detox period with acne, but ultimately, evening primrose oil significantly alleviated my conditions, including the pain from endometriosis and heavy periods, improving my overall well-being.
2
Pain relief and bleeding
6 people found this helpful
Evening primrose oil relieved pain from endometriosis, but thinning the blood led to heavier menstruation. It’s a double-edged sword; while the pain was alleviated, the increased blood flow during menstruation was concerning.
7.5
Eased menstrual symptoms
1 people found this helpful
I began taking Solgar Evening Primrose Oil as my gynecologist suggested it for relieving menstrual pain. I noticed a significant reduction in irritability and menstrual discomfort right from the start. The heaviness and blood clots also decreased, leading to a more manageable cycle. Additionally, my skin became smoother, improving its overall condition. It is beneficial for women's health overall.
6
Lowered prolactin levels
1 people found this helpful
I have been using this oil since 2019, and it effectively lowers my prolactin levels and improves my cycle. I take it for two months twice a year. While it can lead to blood thinning, it also helps with hot flashes and slightly increases libido. I sometimes pierce the capsules to use on my skin. The quality of this oil is among the best I’ve tried.
7.5
Lowers cholesterol
Suitable for those over forty, this oil helps lower cholesterol and is beneficial for hair, heart, and skin. The taste is acceptable and has good quality when taken with Omega supplements.
Frequently Asked Questions
7.5
Eased menstrual symptoms
1 people found this helpful
I began taking Solgar Evening Primrose Oil as my gynecologist suggested it for relieving menstrual pain. I noticed a significant reduction in irritability and menstrual discomfort right from the start. The heaviness and blood clots also decreased, leading to a more manageable cycle. Additionally, my skin became smoother, improving its overall condition. It is beneficial for women's health overall.
9
Improved menstrual cycle
5 people found this helpful
My experience with evening primrose oil began after struggling with endometriosis and blood clots. After two months of taking it, my cycle normalised, and the fibroids ceased to be palpable. My skin completely transformed; it is now soft, smooth, and clear. I did have an initial detox period with acne, but ultimately, evening primrose oil significantly alleviated my conditions, including the pain from endometriosis and heavy periods, improving my overall well-being.
0
Increased heart rate
5 people found this helpful
After taking this oil, I felt unwell; it lowered my blood pressure and increased my heart rate. For anyone with normal blood pressure, I couldn’t recommend it, as it posed issues for me after just a week of use.
2
Pain relief and bleeding
6 people found this helpful
Evening primrose oil relieved pain from endometriosis, but thinning the blood led to heavier menstruation. It’s a double-edged sword; while the pain was alleviated, the increased blood flow during menstruation was concerning.
0
Lowered blood pressure
I found that evening primrose oil significantly reduced my blood pressure to critical levels. This was particularly troubling as I have a history of low blood pressure already.
7.5
Lowers cholesterol
Suitable for those over forty, this oil helps lower cholesterol and is beneficial for hair, heart, and skin. The taste is acceptable and has good quality when taken with Omega supplements.
4
Reduced menstrual pain
3 people found this helpful
This is a very good supplement. After one month of taking one capsule daily, my menstrual pain disappeared, and my cycle improved remarkably. Doctors had said the pain was normal for sixteen years. Be cautious, as this oil does thin the blood.
6
Lowered prolactin levels
1 people found this helpful
I have been using this oil since 2019, and it effectively lowers my prolactin levels and improves my cycle. I take it for two months twice a year. While it can lead to blood thinning, it also helps with hot flashes and slightly increases libido. I sometimes pierce the capsules to use on my skin. The quality of this oil is among the best I’ve tried.
8
Evening primrose oil reduces clotting risk
We investigated how evening primrose oil (EPO) influences blood clotting when paired with celecoxib, a medication linked to thrombotic events. Using a mouse model, we administered celecoxib alongside EPO or forskolin for four weeks, followed by a prothrombotic challenge.
Our findings suggest that while celecoxib increased thrombotic markers, the addition of EPO significantly reduced this prothrombotic effect. This indicates that EPO may help offset some negative cardiovascular impacts of celecoxib, proving its potential in clinical use.
Our findings suggest that while celecoxib increased thrombotic markers, the addition of EPO significantly reduced this prothrombotic effect. This indicates that EPO may help offset some negative cardiovascular impacts of celecoxib, proving its potential in clinical use.
8
We investigated how evening primrose oil (EPO) affects blood clotting and blood pressure fluctuations caused by celecoxib in rats. Our study showed that celecoxib raised blood pressure and sped up blood clotting by increasing platelet activity. While EPO helped lower blood pressure and reduced platelet aggregation, omega-3 fatty acids did not have the same effect. This suggests EPO could be a helpful supplement to mitigate cardiovascular risks linked to celecoxib treatment.
9
We explored how evening primrose oil might affect blood clotting in rabbits fed a high-cholesterol diet. Using a group of 40 rabbits, we supplemented their diet for 6 weeks with evening primrose oil.
The results showed promising anti-thrombotic effects. Evening primrose oil reduced cholesterol levels and improved good HDL cholesterol. Additionally, it lessened platelet adhesion to the endothelium and decreased signs of vascular damage.
Overall, we found that this dietary supplement can enhance endothelial health and may help reduce clot formation.
The results showed promising anti-thrombotic effects. Evening primrose oil reduced cholesterol levels and improved good HDL cholesterol. Additionally, it lessened platelet adhesion to the endothelium and decreased signs of vascular damage.
Overall, we found that this dietary supplement can enhance endothelial health and may help reduce clot formation.
8
We examined the effects of evening primrose oil (EPO) on blood platelet aggregation, a key factor in blood clot formation. Over six weeks, 40 male rabbits were divided into groups and fed either a normal diet or an atherogenic diet, with some receiving EPO.
The atherogenic diet increased platelet aggregation significantly. However, EPO supplementation notably reduced this hyperaggregation to normal levels. Additionally, it helped lower thromboxane levels and lipid peroxides, which are markers linked to clotting issues.
Overall, these findings suggest that EPO may offer protective benefits against excessive blood clotting in diets high in unhealthy fats.
The atherogenic diet increased platelet aggregation significantly. However, EPO supplementation notably reduced this hyperaggregation to normal levels. Additionally, it helped lower thromboxane levels and lipid peroxides, which are markers linked to clotting issues.
Overall, these findings suggest that EPO may offer protective benefits against excessive blood clotting in diets high in unhealthy fats.
References
- Mosaad SM, Zaitone SA, Ahmed AA, Abo-Elmatty DM, El-Baz AA, et al. Evening primrose oil or forskolin ameliorates celecoxib-enhanced upregulation of tissue factor expression in mice subjected to lipopolysaccharide-induced endotoxemia. Naunyn Schmiedebergs Arch Pharmacol. 2017;390:483. doi:10.1007/s00210-017-1342-y
- Zaitone SA, Moustafa YM, Mosaad SM, El-Orabi NF. Effect of evening primrose oil and ω-3 polyunsaturated fatty acids on the cardiovascular risk of celecoxib in rats. J Cardiovasc Pharmacol. 2011;58:72. doi:10.1097/FJC.0b013e31821c8353
- Villalobos MA, De La Cruz JP, Martín-Romero M, Carmona JA, Smith-Agreda JM, et al. Effect of dietary supplementation with evening primrose oil on vascular thrombogenesis in hyperlipemic rabbits. Thromb Haemost. 1998;80:696.
- De La Cruz JP, Martín-Romero M, Carmona JA, Villalobos MA, Sánchez de la Cuesta F. Effect of evening primrose oil on platelet aggregation in rabbits fed an atherogenic diet. Thromb Res. 1997;87:141.
- Belch JJ, Shaw B, O'Dowd A, Saniabadi A, Leiberman P, et al. Evening primrose oil (Efamol) in the treatment of Raynaud's phenomenon: a double blind study. Thromb Haemost. 1985;54:490.
