Overview
SCIENTIFIC SCORE
Questionable
Based on 16 Researches
6.5
USERS' SCORE
Good
Based on 27 Reviews
8.8
Supplement Facts
Serving Size: 1 Softgel
Amount Per Serving
%DV
Calories
15
Total Fat
1.5 g
2%**
Polyunsaturated Fat
1 g
***
Evening Primrose Oil (Seed) providing:
1300 mg
***
Linoleic Acid
949 mg
***
Gamma-Linolenic Acid
117 mg
***
Top Medical Research Studies
9
We explored the effects of evening primrose oil on children's atopic eczema over a 20-week period. Initially, we observed that kids who took this oil showed significant improvement in their skin conditions after just four weeks. Remarkably, those benefits continued throughout the entire treatment duration. Along with these clinical improvements, we also noted changes in the fatty acid composition in the children's blood cells. Despite these positive findings, it's worth noting that opinions about the effectiveness of evening primrose oil vary among researchers, making the overall consensus somewhat unclear.
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7
We explored the effects of evening primrose oil (EPO) on Korean patients with mild atopic dermatitis through a well-structured randomized, double-blinded, placebo-controlled clinical study.
Fifty participants took either EPO or a placebo for four months. By the end of the study, those who received EPO showed significant improvements in their eczema symptoms compared to the placebo group.
While some slight improvements in skin hydration and transepidermal water loss were noted, they weren't statistically significant. Overall, we found EPO to be a safe and effective option for managing mild atopic dermatitis.
Fifty participants took either EPO or a placebo for four months. By the end of the study, those who received EPO showed significant improvements in their eczema symptoms compared to the placebo group.
While some slight improvements in skin hydration and transepidermal water loss were noted, they weren't statistically significant. Overall, we found EPO to be a safe and effective option for managing mild atopic dermatitis.
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7
We examined the effects of evening primrose oil on eczema by studying 40 patients over eight weeks. The participants were split into two groups: one receiving 160 mg daily and the other 320 mg twice daily.
Both groups showed a reduction in eczema symptoms as measured by the Eczema Area Severity Index (EASI) scores. Interestingly, while the higher dose group had more significant fatty acid level improvements, both doses appeared effective in managing eczema symptoms.
Overall, this study suggests that evening primrose oil may help alleviate eczema without notable side effects.
Both groups showed a reduction in eczema symptoms as measured by the Eczema Area Severity Index (EASI) scores. Interestingly, while the higher dose group had more significant fatty acid level improvements, both doses appeared effective in managing eczema symptoms.
Overall, this study suggests that evening primrose oil may help alleviate eczema without notable side effects.
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Most Useful Reviews
9.5
Eczema relief but hormonal benefits
Evening primrose oil is remarkable for women's health, particularly with conditions like PMS and menopause. It helps in regulating hormonal balance and may support conception, benefiting those with gynaecological issues. Additionally, it's effective in reducing skin problems, such as dryness and eczema, while promoting overall health. Regular use potentially reduces the risk of heart disease too.
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9.5
Good for skin conditions
Evening primrose oil is excellent for dry skin and issues like eczema and dermatitis. It has helped me significantly, providing noticeable relief and better skin overall.
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10
Quick eczema relief
Quickly cured my eczema! I'm a 30-year-old female, and I have seasonal eczema in the spring. It's unsightly and burns. I started using this supplement, and it cured my eczema in just a few days! This product is amazing, with no side effects noticed. I take 2-3 per day and will continue to do so!
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Medical Researches
SCIENTIFIC SCORE
Questionable
Based on 16 Researches
6.5
- All Researches
9
Evening primrose oil shows promise
We examined nine controlled trials to understand how evening primrose oil, specifically Epogam, impacts atopic eczema.
Both patients and doctors noted significant improvements in skin symptoms, such as dryness and itchiness, especially in the initial parallel studies.
However, while improvements were observed in crossover trials, the difference compared to placebo didn’t reach statistical significance for doctor scores.
Importantly, patients experienced a notable reduction in itch severity, underscoring Epogam's potential benefits for those struggling with eczema.
Both patients and doctors noted significant improvements in skin symptoms, such as dryness and itchiness, especially in the initial parallel studies.
However, while improvements were observed in crossover trials, the difference compared to placebo didn’t reach statistical significance for doctor scores.
Importantly, patients experienced a notable reduction in itch severity, underscoring Epogam's potential benefits for those struggling with eczema.
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9
We investigated the effects of evening primrose oil on children with atopic eczema. In a focused study, 24 children were divided into two groups: one received a higher dose of evening primrose oil, while the other got a placebo.
After just four weeks, we observed significant improvement in eczema symptoms among those treated with evening primrose oil compared to the placebo group. This suggests that evening primrose oil can positively influence children's eczema, potentially due to its impact on essential fatty acids.
After just four weeks, we observed significant improvement in eczema symptoms among those treated with evening primrose oil compared to the placebo group. This suggests that evening primrose oil can positively influence children's eczema, potentially due to its impact on essential fatty acids.
Read More
9
We explored the effects of evening primrose oil on children's atopic eczema over a 20-week period. Initially, we observed that kids who took this oil showed significant improvement in their skin conditions after just four weeks. Remarkably, those benefits continued throughout the entire treatment duration. Along with these clinical improvements, we also noted changes in the fatty acid composition in the children's blood cells. Despite these positive findings, it's worth noting that opinions about the effectiveness of evening primrose oil vary among researchers, making the overall consensus somewhat unclear.
Read More
8
Anti-inflammatory potential of EPO
The study explored the anti-inflammatory effects of long-chain fatty alcohols derived from evening primrose oil (EPO). We discovered that these compounds reduced nitric oxide production and curbed the secretion of certain inflammatory cytokines in lab tests using murine macrophages.
However, while the results point to the potential benefits of EPO in managing inflammation, this study primarily involved in vitro analyses, meaning further research is needed to establish its effectiveness specifically for eczema in humans. Overall, evening primrose oil shows promise, but significant clinical benefits for eczema should be approached with caution.
However, while the results point to the potential benefits of EPO in managing inflammation, this study primarily involved in vitro analyses, meaning further research is needed to establish its effectiveness specifically for eczema in humans. Overall, evening primrose oil shows promise, but significant clinical benefits for eczema should be approached with caution.
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8
Mixed results on evening primrose oil
We explored the effectiveness of evening primrose oil as a treatment for atopic eczema. Controlled clinical trials displayed marked improvements in patients, with reductions in inflammation, dryness, and overall eczema severity compared to the control group. Although some meta-analyses support these positive findings, conflicting results from crossover trials regarding itching relief suggest that more research is necessary.
Overall, evening primrose oil appears to be a safe option, but we still need more studies to fully understand its benefits and efficacy.
Overall, evening primrose oil appears to be a safe option, but we still need more studies to fully understand its benefits and efficacy.
Read More
User Reviews
USERS' SCORE
Good
Based on 27 Reviews
8.8
- All Reviews
- Positive Reviews
- Negative Reviews
9.5
Eczema relief but hormonal benefits
Evening primrose oil is remarkable for women's health, particularly with conditions like PMS and menopause. It helps in regulating hormonal balance and may support conception, benefiting those with gynaecological issues. Additionally, it's effective in reducing skin problems, such as dryness and eczema, while promoting overall health. Regular use potentially reduces the risk of heart disease too.
Read More
9.5
Good for skin conditions
Evening primrose oil is excellent for dry skin and issues like eczema and dermatitis. It has helped me significantly, providing noticeable relief and better skin overall.
Read More
10
Quick eczema relief
Quickly cured my eczema! I'm a 30-year-old female, and I have seasonal eczema in the spring. It's unsightly and burns. I started using this supplement, and it cured my eczema in just a few days! This product is amazing, with no side effects noticed. I take 2-3 per day and will continue to do so!
Read More
10
Eczema relief
For two years, I struggled with eczema on my fingers, causing dryness and cracking. After trying various treatments, I discovered a link between eczema and omega-6 deficiency. I started taking evening primrose oil, and now my eczema has vanished! My menstrual cycle also improved, now being 28 days instead of 35.
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9.5
Hormonal balance and eczema
Due to its high content of polyunsaturated fatty acids, evening primrose oil significantly helps with PMS and menopause symptoms, regulates hormonal balance, and has excellent effects on the skin, hair, and nails. It's also effective in preventing skin conditions like eczema and assists in childbirth if needed.
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Frequently Asked Questions
No FAQs are available for this product and symptom.
References
- Vassilopoulou E, Comotti A, Douladiris N, Konstantinou GΝ, Zuberbier T, et al. A systematic review and meta-analysis of nutritional and dietary interventions in randomized controlled trials for skin symptoms in children with atopic dermatitis and without food allergy: An EAACI task force report. Allergy. 2024;79:1708. doi:10.1111/all.16160
- Sharifi M, Nourani N, Sanaie S, Hamedeyazdan S. The effect of Oenothera biennis (Evening primrose) oil on inflammatory diseases: a systematic review of clinical trials. BMC Complement Med Ther. 2024;24:89. doi:10.1186/s12906-024-04378-5
- Chung BY, Park SY, Jung MJ, Kim HO, Park CW. Effect of Evening Primrose Oil on Korean Patients With Mild Atopic Dermatitis: A Randomized, Double-Blinded, Placebo-Controlled Clinical Study. Ann Dermatol. 2018;30:409. doi:10.5021/ad.2018.30.4.409
- Vieira BL, Lim NR, Lohman ME, Lio PA. Complementary and Alternative Medicine for Atopic Dermatitis: An Evidence-Based Review. Am J Clin Dermatol. 2016;17:557.
- Montserrat-de la Paz S, García-Giménez MD, Ángel-Martín M, Pérez-Camino MC, Fernández Arche A. Long-chain fatty alcohols from evening primrose oil inhibit the inflammatory response in murine peritoneal macrophages. J Ethnopharmacol. 2014;151:131. doi:10.1016/j.jep.2013.10.012
- Chung BY, Kim JH, Cho SI, Ahn IS, Kim HO, et al. Dose-dependent effects of evening primrose oil in children and adolescents with atopic dermatitis. Ann Dermatol. 2013;25:285. doi:10.5021/ad.2013.25.3.285
- Bamford JT, Ray S, Musekiwa A, van Gool C, Humphreys R, et al. Oral evening primrose oil and borage oil for eczema. Cochrane Database Syst Rev. 2013;2013:CD004416. doi:10.1002/14651858.CD004416.pub2
- Morse NL, Clough PM. A meta-analysis of randomized, placebo-controlled clinical trials of Efamol evening primrose oil in atopic eczema. Where do we go from here in light of more recent discoveries?. Curr Pharm Biotechnol. 2006;7:503.
- Kerscher MJ, Korting HC. Treatment of atopic eczema with evening primrose oil: rationale and clinical results. Clin Investig. 1992;70:167.
- Morse PF, Horrobin DF, Manku MS, Stewart JC, Allen R, et al. Meta-analysis of placebo-controlled studies of the efficacy of Epogam in the treatment of atopic eczema. Relationship between plasma essential fatty acid changes and clinical response. Br J Dermatol. 1989;121:75.
- Bordoni A, Biagi PL, Masi M, Ricci G, Fanelli C, et al. Evening primrose oil (Efamol) in the treatment of children with atopic eczema. Drugs Exp Clin Res. 1988;14:291.
- Biagi PL, Bordoni A, Masi M, Ricci G, Fanelli C, et al. A long-term study on the use of evening primrose oil (Efamol) in atopic children. Drugs Exp Clin Res. 1988;14:285.
- Schalin-Karrila M, Mattila L, Jansen CT, Uotila P. Evening primrose oil in the treatment of atopic eczema: effect on clinical status, plasma phospholipid fatty acids and circulating blood prostaglandins. Br J Dermatol. 1987;117:11.
- Galland L. Increased requirements for essential fatty acids in atopic individuals: a review with clinical descriptions. J Am Coll Nutr. 1986;5:213.
- Bamford JT, Gibson RW, Renier CM. Atopic eczema unresponsive to evening primrose oil (linoleic and gamma-linolenic acids). J Am Acad Dermatol. 1985;13:959.
- Manku MS, Horrobin DF, Morse NL, Wright S, Burton JL. Essential fatty acids in the plasma phospholipids of patients with atopic eczema. Br J Dermatol. 1984;110:643.
