Bought these when we first started TTC with baby #1. I didn't realize actually how beneficial these were to treatment of Antibiotic injuries. I had bactrim for a while and bactrim actually synthesizes to tetrahydrofolate (I think that's what it's called, could be wrong) DNA in your system and therefore depletes it in it's entirety to the point that you can develop serious side effects (like I did). Anyway, I took this every day religiously along with supplementation of a prenatal vitamin and lots of veggies and fruits. my POTS is starting to disappear now! I thought POTS was a chronic condition but this has helped me not only conceive but also stop blood from rushing and staying in my legs. POTS is basically nervous system damage that doctors have no idea how to treat because they don't use natural treatment to poison (thanks John D. Rockefeller for your amazing medical curriculum that kills millions of people a year and makes them suffer with "chronic" conditions) But seriously after taking a crap ton of folate my POTS is basically gone. I also supplemented with Thiamin and vitamin C so that combination works (at least for me) very well. Definitely recommend! Love it! The pill is also very small and not hard to swallow. I dip it in honey though because it is a bit bitter sometimes to swallow, especially if you suck at swallowing pills like me. Overall, I love this stuff! You also get great value for the amount of folate and folic acid you get. This will last me for a very long time. HIGHLY RECOMMEND!