Magnetic capture of blood outgrowth endothelial cells to the luminal surface of magnetizable stent-grafts promotes healing in a porcine pseudoaneurysm model.
We explored how magnetizable stent-grafts can improve healing in carotid artery pseudoaneurysms by investigating their ability to capture blood outgrowth endothelial cells.
In a porcine model, we compared magnetic stent-grafts with standard non-magnetic ones. The results showed that the magnetic stent-grafts not only occluded all nine pseudoaneurysms but also achieved better cell capture and endothelial growth.
Essentially, the magnetic properties enhanced the healing process, leading to less thrombosis compared to non-magnetic counterparts. This innovative approach could reduce complications associated with these medical devices.
Read More
9
ESA and iron enhance surgery outcomes
Use of preoperative erythropoietin-stimulating agents is associated with decreased thrombotic adverse events compared to red blood cell transfusion in surgical patients with anaemia.
We aimed to understand how preoperative treatments like erythropoietin-stimulating agents (ESAs) and intravenous (IV) iron influence the risk of blood clots in surgical patients dealing with anaemia.
In our investigation, we found that patients who received ESAs—whether accompanied by IV iron or not—had lower risks of serious post-operative complications, including blood clots, compared to those who were given red blood cell transfusions. Specifically, those treated with ESAs without IV iron showed significant reductions in mortality and the occurrence of venous thromboembolic events.
Interestingly, when IV iron was combined with ESAs, it appeared to further enhance outcomes, notably improving survival rates. Our results suggest that combining these treatments might yield benefits for patients undergoing surgery, reflected in higher haemoglobin levels and fewer complications compared to traditional blood transfusions.
Read More
4
Iron's unclear role in DVT
May-Thurner Syndrome: An Unusual Case of Unilateral Severe Deep Vein Thrombosis in a Middle-Aged Women.
We explored a 50-year-old woman who came to us with noticeable swelling and pain in her left leg lasting ten days. Upon evaluation, we found that she had deep vein thrombosis (DVT) associated with May-Thurner Syndrome (MTS), where a vein is compressed by an artery. Initially, her blood tests showed normocytic anemia, yet the tests for blood clotting disorders returned normal.
Treatment began with anticoagulation therapy using enoxaparin, coupled with iron supplementation. While iron is typically known for helping with anemia, its specific effect on blood clot resolution in this case remains unclear. Our patient's initial treatments were expanded to include catheter-directed thrombolysis to dissolve the clot, followed by a procedure to relieve venous compression.
We observed significant success in reducing the thrombus burden and restoring blood flow post-stenting. However, we noted that the role of iron supplementation alone in treating the blood clot is ambiguous when combined with other therapies. Thus, while iron is essential for overall health and could play a supportive role, its independent effectiveness against DVT is undetermined in this scenario.
Read More
Most Useful Reviews
9
Symptoms alleviated
4 people found this helpful
I was identified with anaemia and began treatment recently. I noticed that dizziness from the anaemia has disappeared. I'm looking forward to my next blood test, as I feel significantly better overall.
Read More
9
Effective treatment
3 people found this helpful
This iron supplement literally saved me from needing a fourth blood transfusion. My levels were so low that my doctor suggested a transfusion. After taking two pills daily for three months, my hemoglobin rose from 8 to 12, and my iron from 15 to 40! There's no further proof required; it works!
Read More
9
Effective treatment
3 people found this helpful
Helped with anaemia. My spouse's blood test revealed a low haemoglobin of 79. Despite feeling well, the therapist didn’t believe it, but a retest confirmed the low level. After taking Sorbifer Durules for a month, we switched to Iron of the Sun based on positive reviews. We also added vitamin C. After 1.6 months, his haemoglobin rose to 144 without gastrointestinal side effects. It's rewarding to find an affordable and effective solution for health, which is paramount in life.
Use of preoperative erythropoietin-stimulating agents is associated with decreased thrombotic adverse events compared to red blood cell transfusion in surgical patients with anaemia.
We aimed to understand how preoperative treatments like erythropoietin-stimulating agents (ESAs) and intravenous (IV) iron influence the risk of blood clots in surgical patients dealing with anaemia.
In our investigation, we found that patients who received ESAs—whether accompanied by IV iron or not—had lower risks of serious post-operative complications, including blood clots, compared to those who were given red blood cell transfusions. Specifically, those treated with ESAs without IV iron showed significant reductions in mortality and the occurrence of venous thromboembolic events.
Interestingly, when IV iron was combined with ESAs, it appeared to further enhance outcomes, notably improving survival rates. Our results suggest that combining these treatments might yield benefits for patients undergoing surgery, reflected in higher haemoglobin levels and fewer complications compared to traditional blood transfusions.
Read More
9
Magnetic stent-grafts improve healing
Magnetic capture of blood outgrowth endothelial cells to the luminal surface of magnetizable stent-grafts promotes healing in a porcine pseudoaneurysm model.
We explored how magnetizable stent-grafts can improve healing in carotid artery pseudoaneurysms by investigating their ability to capture blood outgrowth endothelial cells.
In a porcine model, we compared magnetic stent-grafts with standard non-magnetic ones. The results showed that the magnetic stent-grafts not only occluded all nine pseudoaneurysms but also achieved better cell capture and endothelial growth.
Essentially, the magnetic properties enhanced the healing process, leading to less thrombosis compared to non-magnetic counterparts. This innovative approach could reduce complications associated with these medical devices.
Read More
4
Iron's unclear role in DVT
May-Thurner Syndrome: An Unusual Case of Unilateral Severe Deep Vein Thrombosis in a Middle-Aged Women.
We explored a 50-year-old woman who came to us with noticeable swelling and pain in her left leg lasting ten days. Upon evaluation, we found that she had deep vein thrombosis (DVT) associated with May-Thurner Syndrome (MTS), where a vein is compressed by an artery. Initially, her blood tests showed normocytic anemia, yet the tests for blood clotting disorders returned normal.
Treatment began with anticoagulation therapy using enoxaparin, coupled with iron supplementation. While iron is typically known for helping with anemia, its specific effect on blood clot resolution in this case remains unclear. Our patient's initial treatments were expanded to include catheter-directed thrombolysis to dissolve the clot, followed by a procedure to relieve venous compression.
We observed significant success in reducing the thrombus burden and restoring blood flow post-stenting. However, we noted that the role of iron supplementation alone in treating the blood clot is ambiguous when combined with other therapies. Thus, while iron is essential for overall health and could play a supportive role, its independent effectiveness against DVT is undetermined in this scenario.
Read More
User Reviews
USERS' SCORE
Medium or Average
Based on 14 Reviews
6.5
All Reviews
Positive Reviews
Negative Reviews
9
Symptoms alleviated
4 people found this helpful
I was identified with anaemia and began treatment recently. I noticed that dizziness from the anaemia has disappeared. I'm looking forward to my next blood test, as I feel significantly better overall.
Read More
9
Effective treatment
3 people found this helpful
This iron supplement literally saved me from needing a fourth blood transfusion. My levels were so low that my doctor suggested a transfusion. After taking two pills daily for three months, my hemoglobin rose from 8 to 12, and my iron from 15 to 40! There's no further proof required; it works!
Read More
9
Effective treatment
3 people found this helpful
Helped with anaemia. My spouse's blood test revealed a low haemoglobin of 79. Despite feeling well, the therapist didn’t believe it, but a retest confirmed the low level. After taking Sorbifer Durules for a month, we switched to Iron of the Sun based on positive reviews. We also added vitamin C. After 1.6 months, his haemoglobin rose to 144 without gastrointestinal side effects. It's rewarding to find an affordable and effective solution for health, which is paramount in life.
Read More
9
Health restored
3 people found this helpful
Taking this dietary supplement quickly normalised my menstrual cycle, and my blood pressure stabilised. I noticed significant improvements like better sleep and reduced headaches promptly after starting the treatment. No adverse side effects, and I am now feeling great!
Read More
9
Life-changing results
2 people found this helpful
My life changed when I started taking Gentle Iron for iron deficiency anaemia. I had severe symptoms, including lethargy and headaches. After starting this supplement, I felt better almost immediately and became productive again. My hemoglobin and ferritin levels normalized after two months of use; I even continue monitoring them with my doctor.
A blood clot is a mass of blood that changes from a liquid to a gel, effectively forming a plug that can stop bleeding. This natural process, known as coagulation, is critical for preventing excessive blood loss when you sustain an injury. Blood clots can occur in various areas of the body, typically at the site of a wound, but they can also form within blood vessels without an obvious injury, which may lead to serious health complications.
While blood clots are essential for healing, they can pose significant health risks if they form inappropriately. For example, a deep vein thrombosis (DVT) occurs when a clot forms in a deep vein, usually in the legs, and can travel to the lungs, causing a life-threatening condition called a pulmonary embolism. Risk factors for blood clots include prolonged immobility, certain medical conditions, and the use of specific medications, among others. It’s important to recognize the symptoms of abnormal clotting, such as swelling, pain, and redness in the affected area, and seek medical attention if they occur.
Iron is a chemical element with the symbol Fe, derived from the Latin word "ferrum." It is a metal that is known for its strength and versatility, making it one of the most widely used materials in construction, manufacturing, and various industrial applications. Iron is the fourth most abundant element in the universe by mass and is primarily obtained through the mining of iron ores, such as hematite and magnetite. Once mined, it undergoes processes like smelting and refining to produce usable forms like cast iron, wrought iron, and steel.
In addition to its industrial uses, iron is also crucial for human health, as it plays a significant role in the production of hemoglobin, the protein in red blood cells responsible for transporting oxygen throughout the body. A deficiency in iron can lead to anemia, characterized by fatigue and weakened immunity. Overall, iron is a fundamental element that supports modern infrastructure and is vital for maintaining good health.
Based on user reviews, the time it takes to see results from an iron supplement for blood-related issues varies significantly among individuals. Some users reported noticeable improvements in as little as 15 days. For instance, one reviewer mentioned that after taking "Gentle Iron," their dizziness disappeared, and they felt more energetic within two weeks Read Review. Others have shared that they observed significant changes over a month or more, with one user’s hemoglobin level rising after 1.6 months of use Read Review.
Conversely, some users experienced no improvement even after two to three months of consistent use, leading them to consider alternative treatments Read ReviewRead Review. The effectiveness of these supplements can depend on various factors, including individual health conditions and the root causes of anemia or low iron levels. Overall, while some users found immediate relief, others required a longer trial period or sought different treatments.
No, the supplement in question does not appear to be strongly supported by scientific research specifically targeting blood clots. While some studies involving iron supplementation have been conducted, their conclusions regarding its independent effectiveness against deep vein thrombosis (DVT) are ambiguous. For instance, one study outlined a case of a patient with DVT who received iron supplementation in conjunction with anticoagulation treatment. However, the specific role of iron in resolving the blood clot was unclear, indicating that while it might support overall health, its impact on DVT management is not well-defined [1].
Another study focused on preoperative treatments like erythropoietin-stimulating agents (ESAs) combined with intravenous (IV) iron, which seemed to lower the risk of blood clots in surgical patients. This indicates a potential benefit when used in a specific context, but it doesn’t firmly establish a direct link between stand-alone iron supplementation and the prevention or treatment of blood clots [2]. Overall, more targeted research is needed to determine the effectiveness of this supplement for individuals specifically dealing with blood clot issues.
Based on user reviews, individuals have reported various improvements in their symptoms after using iron supplements. Many users noted significant enhancements in their overall well-being and specific symptoms associated with anemia. For instance, one reviewer experienced an increase in hemoglobin levels from 8 to 12 after three months of use, which helped them avoid a fourth blood transfusion Read Review. Another stated that their dizziness and lethargy improved almost immediately after starting Gentle Iron, with further normalization of their hemoglobin and ferritin levels observed over two months Read Review.
Moreover, some users mentioned additional benefits beyond hemoglobin improvement, including better sleep, a stabilized menstrual cycle, and reduced headaches Read Review. However, it is essential to note that individual results can vary significantly; while some users reported rapid improvements, others saw no change even after extended use, leading to discontinuation of the product Read Review. This highlights the importance of personalized health assessments and consulting with healthcare professionals when evaluating iron supplementation.
Based on user reviews, there appears to be a notable interest in combining this iron supplement with other vitamins and supplements, particularly Vitamin C, to enhance its effectiveness in treating blood-related issues like anemia. One user mentioned adding Vitamin C while switching from another iron supplement and reported an increase in hemoglobin from 79 to 144 in just over a month Read Review. Users seem to believe that such combinations may maximize the benefits of the iron supplement, especially in addressing their specific blood health concerns.
However, other users reported a range of experiences with the supplement on its own, with some affirming its effectiveness while others encountered setbacks and suboptimal outcomes. One reviewer noted they could not improve their iron levels even after three months of consistent use before reverting to a different supplement for blood clot issues Read Review. This variability suggests that individual responses to the iron supplement may differ markedly, and combining it with additional supplementation should be approached with caution, ideally under the guidance of a healthcare professional.
Based on user reviews, the effectiveness of iron supplements for treating blood-related issues varies significantly among individuals. Some users reported substantial improvements in their hemoglobin and iron levels after consistent use of specific iron supplements. For instance, one user noted that after taking two pills daily for three months, their hemoglobin rose dramatically from 8 to 12, indicating a positive increase in iron levels that helped them avoid a blood transfusion Read Review. Another user mentioned feeling better and seeing normalization in their hemoglobin levels within just over a month of treatment Read Review.
Conversely, there are reviews highlighting negative experiences with their iron supplements. Some users reported no improvement in their iron levels despite prolonged use, and in some cases, they experienced adverse side effects that made them reconsider their treatment options Read Review. A different user shared their struggle with side effects and lack of improvement, stating they would not recommend the supplement for blood clot concerns Read Review. Overall, while some users found effective dosing strategies, others experienced insufficient results, suggesting that dosage and individual tolerance are critical factors in the therapeutic efficacy of iron supplements.
7.5
Energised and better
1 people found this helpful
After a recent blood test revealing low hemoglobin of 100, I began taking "Gentle Iron." Within 15 days, my dizziness vanished, and I felt more energetic. My menstrual cycle also became less painful. I'll retest after my course, but for now, I'm very pleased with the results.
9
Effective treatment
3 people found this helpful
Helped with anaemia. My spouse's blood test revealed a low haemoglobin of 79. Despite feeling well, the therapist didn’t believe it, but a retest confirmed the low level. After taking Sorbifer Durules for a month, we switched to Iron of the Sun based on positive reviews. We also added vitamin C. After 1.6 months, his haemoglobin rose to 144 without gastrointestinal side effects. It's rewarding to find an affordable and effective solution for health, which is paramount in life.
2
Declined iron levels
5 people found this helpful
Unfortunately, after three months of taking this iron, my levels dropped from 128 to 93. I bought it based on positive reviews, but I’d suggest monitoring your blood tests closely. I ultimately returned to Fenuls as my treatment for blood clot.
2
Questionable effectiveness
5 people found this helpful
I had low haemoglobin, and the doctor recommended iron supplements. After two months of use, there was no increase in iron levels. I eventually had to resort to intramuscular injections, which did lead to a significant rise in my haemoglobin. This experience made me question the effectiveness of this iron supplement for treating blood clot.
9
Effective treatment
3 people found this helpful
This iron supplement literally saved me from needing a fourth blood transfusion. My levels were so low that my doctor suggested a transfusion. After taking two pills daily for three months, my hemoglobin rose from 8 to 12, and my iron from 15 to 40! There's no further proof required; it works!
9
Life-changing results
2 people found this helpful
My life changed when I started taking Gentle Iron for iron deficiency anaemia. I had severe symptoms, including lethargy and headaches. After starting this supplement, I felt better almost immediately and became productive again. My hemoglobin and ferritin levels normalized after two months of use; I even continue monitoring them with my doctor.
9
Health restored
3 people found this helpful
Taking this dietary supplement quickly normalised my menstrual cycle, and my blood pressure stabilised. I noticed significant improvements like better sleep and reduced headaches promptly after starting the treatment. No adverse side effects, and I am now feeling great!
2
No benefit observed
1 people found this helpful
This iron supplement didn’t help at all. Blood tests confirmed an iron deficiency, and I will not continue using it for this 90-year-old man with concerns about blood clot.
4
Iron's unclear role in DVT
May-Thurner Syndrome: An Unusual Case of Unilateral Severe Deep Vein Thrombosis in a Middle-Aged Women.
We explored a 50-year-old woman who came to us with noticeable swelling and pain in her left leg lasting ten days. Upon evaluation, we found that she had deep vein thrombosis (DVT) associated with May-Thurner Syndrome (MTS), where a vein is compressed by an artery. Initially, her blood tests showed normocytic anemia, yet the tests for blood clotting disorders returned normal.
Treatment began with anticoagulation therapy using enoxaparin, coupled with iron supplementation. While iron is typically known for helping with anemia, its specific effect on blood clot resolution in this case remains unclear. Our patient's initial treatments were expanded to include catheter-directed thrombolysis to dissolve the clot, followed by a procedure to relieve venous compression.
We observed significant success in reducing the thrombus burden and restoring blood flow post-stenting. However, we noted that the role of iron supplementation alone in treating the blood clot is ambiguous when combined with other therapies. Thus, while iron is essential for overall health and could play a supportive role, its independent effectiveness against DVT is undetermined in this scenario.
9
ESA and iron enhance surgery outcomes
Use of preoperative erythropoietin-stimulating agents is associated with decreased thrombotic adverse events compared to red blood cell transfusion in surgical patients with anaemia.
We aimed to understand how preoperative treatments like erythropoietin-stimulating agents (ESAs) and intravenous (IV) iron influence the risk of blood clots in surgical patients dealing with anaemia.
In our investigation, we found that patients who received ESAs—whether accompanied by IV iron or not—had lower risks of serious post-operative complications, including blood clots, compared to those who were given red blood cell transfusions. Specifically, those treated with ESAs without IV iron showed significant reductions in mortality and the occurrence of venous thromboembolic events.
Interestingly, when IV iron was combined with ESAs, it appeared to further enhance outcomes, notably improving survival rates. Our results suggest that combining these treatments might yield benefits for patients undergoing surgery, reflected in higher haemoglobin levels and fewer complications compared to traditional blood transfusions.
References
Basu R, Reddy M, Kaabneh A, Mohamedelamin Khidir Ahmed A, Bamne S. May-Thurner Syndrome: An Unusual Case of Unilateral Severe Deep Vein Thrombosis in a Middle-Aged Women. Cureus. 2024;16:e75621. doi:10.7759/cureus.75621
Choi UE, Nicholson RC, Frank SM, Cha S, Cho BC, et al. Use of preoperative erythropoietin-stimulating agents is associated with decreased thrombotic adverse events compared to red blood cell transfusion in surgical patients with anaemia. Vox Sang. 2024;119:1174. doi:10.1111/vox.13729
Oliver AA, Carlson KD, Price C, Banaskiewicz K, Benike A, et al. Magnetic capture of blood outgrowth endothelial cells to the luminal surface of magnetizable stent-grafts promotes healing in a porcine pseudoaneurysm model. Acta Biomater. 2025. doi:10.1016/j.actbio.2025.03.040