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SCIENTIFIC SCORE
Questionable
Based on 3 Researches
6.7
USERS' SCORE
Moderately Good
Based on 58 Reviews
7.1
Supplement Facts
Serving Size: 1 Vegetable Capsule
Amount Per Serving
%DV
Iron (as iron bisglycinate chelate†)
25 mg
139%
Top Medical Research Studies
9
Iron enhances piglet gut health
Dietary Fe-Gly supplementation attenuates enterotoxigenic (ETEC)-induced inflammation response and intestinal barrier dysfunction in piglets.
Study focused on diarrhea reduction
We explored how adding iron, specifically Fe-Gly, to piglets' diets could help combat diarrhea caused by enterotoxigenic E. coli (ETEC) infections. In our study, we administered 50 mg of Fe-Gly to weaned piglets that had been infected, monitoring their growth, diarrhea rates, and overall gut health.
We observed remarkable improvements in the piglets' growth performance, with increases in average daily feed intake and daily gain by over 30%. Most notably, the rate of diarrhea significantly decreased by 40%. Additionally, we found that this iron supplementation raised the levels of total iron binding capacity in piglet serum, suggesting better iron transport and utilization.
Beyond growth metrics, the addition of Fe-Gly also showed potential in alleviating intestinal damage incurred from the ETEC challenge. As a result, we conclude that Fe-Gly not only meets daily iron needs but also reduces the iron available for harmful gut bacteria, promoting better intestinal health in piglets suffering from infections.
We observed remarkable improvements in the piglets' growth performance, with increases in average daily feed intake and daily gain by over 30%. Most notably, the rate of diarrhea significantly decreased by 40%. Additionally, we found that this iron supplementation raised the levels of total iron binding capacity in piglet serum, suggesting better iron transport and utilization.
Beyond growth metrics, the addition of Fe-Gly also showed potential in alleviating intestinal damage incurred from the ETEC challenge. As a result, we conclude that Fe-Gly not only meets daily iron needs but also reduces the iron available for harmful gut bacteria, promoting better intestinal health in piglets suffering from infections.
Read More
7
Iron's mixed effects on diarrhea
Application of longitudinal multilevel zero inflated Poisson regression in modeling of infectious diseases among infants in Ethiopia.
Limited ability to isolate iron effects
We explored the effect of iron supplementation in the form of Micronutrient Powder (MNP) on the duration of diarrhea among infants aged 6 to 11 months. By analyzing longitudinal data, we utilized a sophisticated statistical approach that considered the unique patterns of each child’s health over time.
Our findings revealed some interesting trends. Initially, infants using low-dose iron seemed to experience a greater number of days with diarrhea compared to those who did not use it. However, this pattern flipped as time went on, suggesting that the immediate benefits may vary.
Additionally, we noticed that infants who practiced exclusive breastfeeding for the first six months and supplemented with MNP reported fewer instances of respiratory issues. Overall, we observed that while iron treatment had some impact on respiratory infections, its direct effect on diarrhea was not straightforward.
Therefore, while iron supplementation can be beneficial in some contexts, the results point towards a more complex interaction with diarrhea in infants. This emphasizes the necessity of further investigation into dietary and health practices to enhance child health in our communities.
Our findings revealed some interesting trends. Initially, infants using low-dose iron seemed to experience a greater number of days with diarrhea compared to those who did not use it. However, this pattern flipped as time went on, suggesting that the immediate benefits may vary.
Additionally, we noticed that infants who practiced exclusive breastfeeding for the first six months and supplemented with MNP reported fewer instances of respiratory issues. Overall, we observed that while iron treatment had some impact on respiratory infections, its direct effect on diarrhea was not straightforward.
Therefore, while iron supplementation can be beneficial in some contexts, the results point towards a more complex interaction with diarrhea in infants. This emphasizes the necessity of further investigation into dietary and health practices to enhance child health in our communities.
Read More
4
No significant diarrhea increase
Effects of iron supplements and iron-containing micronutrient powders on the gut microbiome in Bangladeshi infants: a randomized controlled trial.
Investigates iron's safety profile.
We conducted a study to evaluate how iron supplements and iron-containing micronutrient powders (MNPs) affect the gut microbiome and the incidence of diarrhea in infants from rural Bangladesh. Over the course of three months, we gave 923 infants either iron, MNPs, or a placebo while monitoring their gut health.
Interestingly, we found no significant increase in diarrhea among the infants receiving iron supplements or MNPs compared to those given the placebo. This gives us a bit of reassurance regarding the safety of these interventions. Our primary analysis showed no substantial changes in gut microbiome diversity or composition after the treatments.
However, it's worth noting that when we looked closer—without adjusting for multiple comparisons—we observed some changes. Infants receiving iron and MNPs showed a reduction in beneficial gut bacteria, like Bifidobacterium and Lactobacillus, alongside an increase in potentially harmful species like Clostridium. These shifts were more pronounced in infants who already had enough iron at the start of the study.
Overall, while there was no significant increase in diarrhea, the observed shifts in the gut microbiome could raise concerns, especially in well-nourished infants. Our findings highlight the need for further research to understand the complexities of iron treatment fully.
Interestingly, we found no significant increase in diarrhea among the infants receiving iron supplements or MNPs compared to those given the placebo. This gives us a bit of reassurance regarding the safety of these interventions. Our primary analysis showed no substantial changes in gut microbiome diversity or composition after the treatments.
However, it's worth noting that when we looked closer—without adjusting for multiple comparisons—we observed some changes. Infants receiving iron and MNPs showed a reduction in beneficial gut bacteria, like Bifidobacterium and Lactobacillus, alongside an increase in potentially harmful species like Clostridium. These shifts were more pronounced in infants who already had enough iron at the start of the study.
Overall, while there was no significant increase in diarrhea, the observed shifts in the gut microbiome could raise concerns, especially in well-nourished infants. Our findings highlight the need for further research to understand the complexities of iron treatment fully.
Read More
Most Useful Reviews
9.5
No diarrhea experienced
The best iron I have ever used. I experienced no side effects, and my analysis showed everything was fine. I used to have low haemoglobin, but now all indicators, including iron, are normal. The usual iron caused constant diarrhoea, which I do not recall with this product.
Read More
9.5
No side effects
The best iron! I took this during pregnancy for my anaemia. After two months, my iron deficiency improved, and my health got better—no diarrhoea or stomach pain. If you find this helpful, please like it!
Read More
0
Severe diarrhoea
Unfortunately, after three days, this iron supplement caused severe intestinal issues and diarrhoea, leading me to stop taking it.
Read More
Medical Researches
SCIENTIFIC SCORE
Questionable
Based on 3 Researches
6.7
9
Iron enhances piglet gut health
Dietary Fe-Gly supplementation attenuates enterotoxigenic (ETEC)-induced inflammation response and intestinal barrier dysfunction in piglets.
Study focused on diarrhea reduction
We explored how adding iron, specifically Fe-Gly, to piglets' diets could help combat diarrhea caused by enterotoxigenic E. coli (ETEC) infections. In our study, we administered 50 mg of Fe-Gly to weaned piglets that had been infected, monitoring their growth, diarrhea rates, and overall gut health.
We observed remarkable improvements in the piglets' growth performance, with increases in average daily feed intake and daily gain by over 30%. Most notably, the rate of diarrhea significantly decreased by 40%. Additionally, we found that this iron supplementation raised the levels of total iron binding capacity in piglet serum, suggesting better iron transport and utilization.
Beyond growth metrics, the addition of Fe-Gly also showed potential in alleviating intestinal damage incurred from the ETEC challenge. As a result, we conclude that Fe-Gly not only meets daily iron needs but also reduces the iron available for harmful gut bacteria, promoting better intestinal health in piglets suffering from infections.
We observed remarkable improvements in the piglets' growth performance, with increases in average daily feed intake and daily gain by over 30%. Most notably, the rate of diarrhea significantly decreased by 40%. Additionally, we found that this iron supplementation raised the levels of total iron binding capacity in piglet serum, suggesting better iron transport and utilization.
Beyond growth metrics, the addition of Fe-Gly also showed potential in alleviating intestinal damage incurred from the ETEC challenge. As a result, we conclude that Fe-Gly not only meets daily iron needs but also reduces the iron available for harmful gut bacteria, promoting better intestinal health in piglets suffering from infections.
Read More
7
Iron's mixed effects on diarrhea
Application of longitudinal multilevel zero inflated Poisson regression in modeling of infectious diseases among infants in Ethiopia.
Limited ability to isolate iron effects
We explored the effect of iron supplementation in the form of Micronutrient Powder (MNP) on the duration of diarrhea among infants aged 6 to 11 months. By analyzing longitudinal data, we utilized a sophisticated statistical approach that considered the unique patterns of each child’s health over time.
Our findings revealed some interesting trends. Initially, infants using low-dose iron seemed to experience a greater number of days with diarrhea compared to those who did not use it. However, this pattern flipped as time went on, suggesting that the immediate benefits may vary.
Additionally, we noticed that infants who practiced exclusive breastfeeding for the first six months and supplemented with MNP reported fewer instances of respiratory issues. Overall, we observed that while iron treatment had some impact on respiratory infections, its direct effect on diarrhea was not straightforward.
Therefore, while iron supplementation can be beneficial in some contexts, the results point towards a more complex interaction with diarrhea in infants. This emphasizes the necessity of further investigation into dietary and health practices to enhance child health in our communities.
Our findings revealed some interesting trends. Initially, infants using low-dose iron seemed to experience a greater number of days with diarrhea compared to those who did not use it. However, this pattern flipped as time went on, suggesting that the immediate benefits may vary.
Additionally, we noticed that infants who practiced exclusive breastfeeding for the first six months and supplemented with MNP reported fewer instances of respiratory issues. Overall, we observed that while iron treatment had some impact on respiratory infections, its direct effect on diarrhea was not straightforward.
Therefore, while iron supplementation can be beneficial in some contexts, the results point towards a more complex interaction with diarrhea in infants. This emphasizes the necessity of further investigation into dietary and health practices to enhance child health in our communities.
Read More
4
No significant diarrhea increase
Effects of iron supplements and iron-containing micronutrient powders on the gut microbiome in Bangladeshi infants: a randomized controlled trial.
Investigates iron's safety profile.
We conducted a study to evaluate how iron supplements and iron-containing micronutrient powders (MNPs) affect the gut microbiome and the incidence of diarrhea in infants from rural Bangladesh. Over the course of three months, we gave 923 infants either iron, MNPs, or a placebo while monitoring their gut health.
Interestingly, we found no significant increase in diarrhea among the infants receiving iron supplements or MNPs compared to those given the placebo. This gives us a bit of reassurance regarding the safety of these interventions. Our primary analysis showed no substantial changes in gut microbiome diversity or composition after the treatments.
However, it's worth noting that when we looked closer—without adjusting for multiple comparisons—we observed some changes. Infants receiving iron and MNPs showed a reduction in beneficial gut bacteria, like Bifidobacterium and Lactobacillus, alongside an increase in potentially harmful species like Clostridium. These shifts were more pronounced in infants who already had enough iron at the start of the study.
Overall, while there was no significant increase in diarrhea, the observed shifts in the gut microbiome could raise concerns, especially in well-nourished infants. Our findings highlight the need for further research to understand the complexities of iron treatment fully.
Interestingly, we found no significant increase in diarrhea among the infants receiving iron supplements or MNPs compared to those given the placebo. This gives us a bit of reassurance regarding the safety of these interventions. Our primary analysis showed no substantial changes in gut microbiome diversity or composition after the treatments.
However, it's worth noting that when we looked closer—without adjusting for multiple comparisons—we observed some changes. Infants receiving iron and MNPs showed a reduction in beneficial gut bacteria, like Bifidobacterium and Lactobacillus, alongside an increase in potentially harmful species like Clostridium. These shifts were more pronounced in infants who already had enough iron at the start of the study.
Overall, while there was no significant increase in diarrhea, the observed shifts in the gut microbiome could raise concerns, especially in well-nourished infants. Our findings highlight the need for further research to understand the complexities of iron treatment fully.
Read More
User Reviews
USERS' SCORE
Moderately Good
Based on 58 Reviews
7.1
10
Highly recommended
This is one of the best iron preparations I have used! I've been anaemic for years, finding it tough to tolerate most treatments. With this iron, I had no constipation, diarrhoea, or nausea, and my haemoglobin levels improved. I truly recommend it!
10
No diarrhoea experienced
This Gentle Iron is excellent! For ten years, I’ve had iron deficiency anaemia, but this supplement causes no heaviness, swelling, or diarrhoea. I take it separately from food and other medications, and I’m feeling much better with noticeable improvements.
10
No diarrhoea experienced
I’ve been taking Gentle Iron for a while now, and it has not upset my stomach. It neither caused constipation nor diarrhoea, and I saw my ferritin levels rise significantly within four months. I prefer the American version over the European one due to citric acid.
10
No diarrhoea experienced
After years of anaemia with dizziness and weakness, I turned to this iron. Surprisingly, it caused no negative reactions. I felt a significant reduction in symptoms and began taking more each day without experiencing diarrhoea.
10
No diarrhoea experienced
I did not experience any side effects like bloating or diarrhoea compared to other pharmaceutical iron. This product works excellently for me, and I highly recommend it.
