Overview

SCIENTIFIC SCORE
Moderately Effective
Based on 4 Researches
8.1
USERS' SCORE
Moderately Good
Based on 26 Reviews
7
Supplement Facts
Serving Size: 1 Vegetable Capsule
Amount Per Serving
%DV
Iron (as iron bisglycinate chelate†)
25 mg
139%

Top Medical Research Studies

9.5
We examined a case involving an 11-year-old male who experienced adverse effects from taking oral ferrous sulfate tablets to treat iron deficiency anemia. Over two months of treatment, he developed gastritis, which was confirmed through histological analysis during an endoscopy.

The findings revealed iron deposits in the stomach lining, prompting a reassessment of his iron supplementation strategy. We switched him from tablets to a liquid form of iron, which seemed to be gentler on his system.

After four months, a repeat endoscopy indicated a remarkable improvement, with the histological signs of gastritis resolving. This case illustrates that while iron is necessary for treating anemia, the form in which it's administered can significantly impact side effects like gastritis.
Read More
In our exploration of how iron treatment relates to collagenous gastritis (CG) in children, we found that this condition can lead to symptoms like abdominal pain and significant anemia. Over five years, we reviewed the cases of three young patients diagnosed with CG. They all struggled with iron deficiency anemia and experienced varying levels of abdominal discomfort alongside their other symptoms.

Initially, we prescribed oral iron supplements to these patients. Unfortunately, they didn’t respond well due to problems with tolerance, primarily because the supplements intensified their epigastric pain. As a result, we shifted our approach to ferric carboxymaltose (FCM) infusions, which proved effective. This treatment led to noticeable improvements in their anemia and overall well-being.

Overall, our findings highlighted that while oral iron may not always be the best option for children with CG, FCM infusion offered a promising alternative. We did notice that there were no adverse effects with this method, making it a viable option for managing iron deficiency in these patients. Moreover, we found that consistent and supportive care is crucial, as specific treatments still lack established effectiveness in the literature.
Read More
7
Pernicious anemia and iron deficiency
We aimed to understand the connection between iron deficiency and pernicious anemia (PA), a condition where the body lacks vitamin B12 due to autoimmune gastritis.

Our study involved 28 patients recently diagnosed with PA. We found that 75% of these individuals experienced iron deficiency, which could happen at the time of diagnosis or during follow-up visits. Those with iron deficiency often had higher vitamin B12 levels and lower homocysteine, suggesting a unique profile among these patients.

Interestingly, we noted that intravenous iron supplementation appeared to be more effective in normalizing iron status compared to oral iron supplements. This outcome emphasizes the importance of regularly monitoring iron levels in patients with PA since iron deficiency can complicate the overall health management of these individuals.
Read More

Most Useful Reviews

0
Negative experience
Unfortunately, this iron caused constipation and a painful stomach. After two attempts, I found it ineffective for my gastritis.
Read More
9.5
Felt better
This iron supplement has been beneficial. I didn’t take tests initially, but I noticed improvements within a few weeks—less hair loss and overall better health. It does not irritate my gastritis as I take it after meals. It is cost-effective, lasting a long time, so I highly recommend it!
Read More
9.5
Back to normal
I had no issues with digestion while using this iron. Previously, when prescribed Ranferon, I experienced severe stomach pains due to gastritis. I am grateful to have found this alternative, which has restored my normalcy without discomfort.
Read More

Medical Researches

SCIENTIFIC SCORE
Moderately Effective
Based on 4 Researches
8.1
  • All Researches
9.5
We examined a case involving an 11-year-old male who experienced adverse effects from taking oral ferrous sulfate tablets to treat iron deficiency anemia. Over two months of treatment, he developed gastritis, which was confirmed through histological analysis during an endoscopy.

The findings revealed iron deposits in the stomach lining, prompting a reassessment of his iron supplementation strategy. We switched him from tablets to a liquid form of iron, which seemed to be gentler on his system.

After four months, a repeat endoscopy indicated a remarkable improvement, with the histological signs of gastritis resolving. This case illustrates that while iron is necessary for treating anemia, the form in which it's administered can significantly impact side effects like gastritis.
Read More
8
Impact of Iron on Gastritis
We explored the effects of iron treatment on children diagnosed with collagenous gastritis (CG) and lymphocytic gastritis (LG). Over a period from 2000 to 2023, we reviewed cases that revealed a notable increase in diagnoses, highlighting the importance of awareness among healthcare providers.

Out of 31 children observed, iron deficiency anemia was present in 22 of them. The study showed that iron supplementation was commonly used, with 77% of the children receiving it. Notably, we found that after treatment, hemoglobin levels normalized in most cases, indicating that iron may indeed play a significant role in managing anemia associated with these types of gastritis.

However, it's crucial to mention that 29% of the patients required additional iron supplementation even after their levels normalized. This suggests that while iron treatment can benefit those suffering from anemia due to gastritis, it may not completely resolve the underlying issues for everyone. We also noted that repeat endoscopies did not reveal any significant changes in gastric histopathology, which indicates that while the symptoms could improve with treatment, the condition itself might not necessarily change.

Ultimately, our findings encourage healthcare professionals to consider CG and LG more seriously in pediatric patients, especially when treating related conditions like iron deficiency anemia.
Read More
In our exploration of how iron treatment relates to collagenous gastritis (CG) in children, we found that this condition can lead to symptoms like abdominal pain and significant anemia. Over five years, we reviewed the cases of three young patients diagnosed with CG. They all struggled with iron deficiency anemia and experienced varying levels of abdominal discomfort alongside their other symptoms.

Initially, we prescribed oral iron supplements to these patients. Unfortunately, they didn’t respond well due to problems with tolerance, primarily because the supplements intensified their epigastric pain. As a result, we shifted our approach to ferric carboxymaltose (FCM) infusions, which proved effective. This treatment led to noticeable improvements in their anemia and overall well-being.

Overall, our findings highlighted that while oral iron may not always be the best option for children with CG, FCM infusion offered a promising alternative. We did notice that there were no adverse effects with this method, making it a viable option for managing iron deficiency in these patients. Moreover, we found that consistent and supportive care is crucial, as specific treatments still lack established effectiveness in the literature.
Read More
7
Pernicious anemia and iron deficiency
We aimed to understand the connection between iron deficiency and pernicious anemia (PA), a condition where the body lacks vitamin B12 due to autoimmune gastritis.

Our study involved 28 patients recently diagnosed with PA. We found that 75% of these individuals experienced iron deficiency, which could happen at the time of diagnosis or during follow-up visits. Those with iron deficiency often had higher vitamin B12 levels and lower homocysteine, suggesting a unique profile among these patients.

Interestingly, we noted that intravenous iron supplementation appeared to be more effective in normalizing iron status compared to oral iron supplements. This outcome emphasizes the importance of regularly monitoring iron levels in patients with PA since iron deficiency can complicate the overall health management of these individuals.
Read More

User Reviews

USERS' SCORE
Moderately Good
Based on 26 Reviews
7
  • All Reviews
  • Positive Reviews
  • Negative Reviews
0
Negative experience
Unfortunately, this iron caused constipation and a painful stomach. After two attempts, I found it ineffective for my gastritis.
Read More
9.5
Felt better
This iron supplement has been beneficial. I didn’t take tests initially, but I noticed improvements within a few weeks—less hair loss and overall better health. It does not irritate my gastritis as I take it after meals. It is cost-effective, lasting a long time, so I highly recommend it!
Read More
9.5
Back to normal
I had no issues with digestion while using this iron. Previously, when prescribed Ranferon, I experienced severe stomach pains due to gastritis. I am grateful to have found this alternative, which has restored my normalcy without discomfort.
Read More
9.5
No gastric symptoms
These capsules are fantastic for iron deficiency anaemia. I take one daily without any gastric issues, unlike other iron supplements that caused me gastritis or constipation. After two weeks, my dizziness and hypotension symptoms improved significantly.
Read More
9.5
Improved condition
Great drug. I took 2 capsules daily as prescribed, with vitamin C. My ferritin improved from 10 to 41, and my well-being significantly increased, including restoring my strength and eliminating weakness, drowsiness, and dizziness. I have gastritis, yet my stomach feels good, with no metallic taste of iron. Highly recommend.
Read More

Frequently Asked Questions

Gastritis is an inflammation of the stomach lining, which can lead to a range of symptoms including abdominal pain, nausea, vomiting, and indigestion. This condition can be acute, arising suddenly and lasting for a short period, or chronic, developing gradually and persisting over time. Various factors can contribute to gastritis, such as excessive alcohol consumption, prolonged use of nonsteroidal anti-inflammatory drugs (NSAIDs), bacterial infections (most notably Helicobacter pylori), and autoimmune disorders.

Treatment for gastritis often focuses on addressing the underlying cause and might include medications to reduce stomach acid, antibiotics for infections, and lifestyle modifications like avoiding irritating foods and beverages. While many people recover from gastritis with adequate care, it's important to consult a healthcare professional for a proper diagnosis and treatment plan. If left untreated, gastritis can lead to more serious complications, such as stomach ulcers or even an increased risk for gastric cancer.

Iron is a chemical element with the symbol Fe, derived from the Latin word "ferrum." It is a metal that is known for its strength and versatility, making it one of the most widely used materials in construction, manufacturing, and various industrial applications. Iron is the fourth most abundant element in the universe by mass and is primarily obtained through the mining of iron ores, such as hematite and magnetite. Once mined, it undergoes processes like smelting and refining to produce usable forms like cast iron, wrought iron, and steel.

In addition to its industrial uses, iron is also crucial for human health, as it plays a significant role in the production of hemoglobin, the protein in red blood cells responsible for transporting oxygen throughout the body. A deficiency in iron can lead to anemia, characterized by fatigue and weakened immunity. Overall, iron is a fundamental element that supports modern infrastructure and is vital for maintaining good health.

Based on user reviews, it appears that the timeframe for seeing results from iron supplements when dealing with gastritis can vary significantly among individuals. Many users reported noticing improvements within a few weeks of consistent use. For instance, one reviewer indicated that they felt revitalized after 5-6 days of taking the supplement, while another noted significant enhancements in their quality of life within a month (Read Review) (Read Review).

However, it is not uncommon for some users to experience discomfort or no improvement even after prolonged use. For instance, one user mentioned that their gastritis was aggravated after two and a half months without any increase in ferritin levels (Read Review). Ultimately, based on user feedback, while many notice positive changes within weeks, others may require several months before determining the effectiveness of the supplement for gastritis-related issues.

While research suggests that iron supplementation plays a role in managing gastritis, particularly in cases associated with anemia, the evidence is nuanced. For instance, a study highlighted that children suffering from collagenous gastritis (CG) often experience iron deficiency anemia, and iron treatment can help normalize hemoglobin levels in many cases [1]. However, another study cautioned that iron supplements, especially in certain forms, could potentially exacerbate gastritis symptoms, as seen in a young boy who developed gastritis from oral iron tablets [2].

Moreover, the form of iron supplementation can significantly affect its tolerance and efficiency. While some children did poorly with oral iron, alternatives like ferric carboxymaltose infusions demonstrated promising results without adverse effects, suggesting a need for tailored approaches to treatment [4]. Overall, while iron supplementation may support the management of gastritis in specific contexts, the method and context of treatment should be carefully considered to avoid exacerbating the condition.

Users have reported a variety of improvements in their symptoms after taking iron supplements, particularly when managing gastritis. Many individuals noted significant enhancements in their overall health, including increased energy levels, reduced dizziness, and improved ferritin levels. For instance, one user experienced a rise in ferritin from 10 to 41 while feeling significantly better overall without any digestive discomfort (Read Review). Similarly, another reviewer highlighted feeling revitalized after just a few days of use, with noticeable improvements in symptoms like fatigue and hair loss (Read Review).

While many users reported positive outcomes, it's crucial to acknowledge that experiences can vary widely. Some individuals encountered gastrointestinal discomfort or no improvement at all, even after extended use. For example, one user experienced worsening symptoms of gastritis after taking the supplement (Read Review). Overall, while many users found relief and improvements, others faced challenges that highlight the importance of monitoring individual responses to iron supplementation.

Users have reported mixed experiences when combining this iron supplement with other supplements for managing gastritis. Some individuals noted that taking the iron with vitamin C significantly improved their tolerance and benefits. For instance, one reviewer shared that they combined the iron with vitamin C, which helped avoid any gastric irritation and led to a substantial increase in their ferritin levels, ultimately enhancing their overall well-being (Read Review). Similarly, others also reported improvements when they carefully timed their doses, such as taking iron capsules after meals, which helped mitigate discomfort from gastritis (Read Review).

However, not all users found success when combining this supplement with others. Some reported heightened gastric issues, particularly when taken improperly, like on an empty stomach or without considering dietary interactions such as coffee or tea (Read Review). Users emphasized the importance of individual monitoring and adjusting intake as needed, highlighting that while many found relief and increased ferritin levels, others faced exacerbated symptoms when combining the iron supplement with dietary factors (Read Review).

When it comes to finding the right iron dosage for treating gastritis, user reviews indicate a spectrum of experiences. Many users found success with lower doses taken in conjunction with meals, which seemed to mitigate gastrointestinal discomfort. For instance, one reviewer pointed out that they took two capsules daily with vitamin C, resulting in significant improvements in their ferritin levels without any stomach pain, despite having gastritis (Read Review). Another user reported taking a daily capsule with no digestive issues, highlighting how a gentle iron formulation was well tolerated (Read Review).

Conversely, some users experienced adverse effects, particularly when taking iron on an empty stomach or in higher doses. This has led to suggestions that starting with a smaller dose and gradually increasing may be beneficial, especially for those with a history of gastritis. One user mentioned suffering from stomach pain after just two pills, prompting them to stop altogether (Read Review). It's crucial for individuals to monitor their body's reactions and adjust their intake accordingly, as the right dosage can vary significantly based on personal tolerance and the specific formulation of the iron supplement used.

8.8
Improved well-being
I conquered anaemia! This iron supplement is one of the best. It didn’t irritate my gastric mucosa, despite having gastritis. Initially, I experienced a brief bowel disorder, but after 5-6 days, I felt revitalised—better sleep, increased strength, and a healthier glow. My ferritin rose from 25 to 69. I plan to continue for three months to reach at least 100.
9.5
Enhanced mood
It works! After a year of fatigue and confusion due to anaemia, I found my ferritin was 7. I started using this iron, coupled with vitamins C, B, and D3-K2, and noticed improvements within a month. My gastritis tolerates this supplement well, significantly enhancing my quality of life. I’ll retake my tests after finishing the jar.
2.5
No improvement
I took iron bisglycinate for two and a half months, but my ferritin levels did not rise, and my gastritis was aggravated. I hope to try other forms of iron due to my chronic hair loss.
9.5
Improved condition
Great drug. I took 2 capsules daily as prescribed, with vitamin C. My ferritin improved from 10 to 41, and my well-being significantly increased, including restoring my strength and eliminating weakness, drowsiness, and dizziness. I have gastritis, yet my stomach feels good, with no metallic taste of iron. Highly recommend.
8.8
No nausea experienced
This soft iron boosted my ferritin without nausea or pain. I initially feared taking it on an empty stomach, but it worked wonders with vitamin C and L-lysine, easing my gastritis. Despite the lower dosage than my previous iron, it increased my ferritin by 45 units over three months. Follow the advice for best results.
9.5
Felt better
This iron supplement has been beneficial. I didn’t take tests initially, but I noticed improvements within a few weeks—less hair loss and overall better health. It does not irritate my gastritis as I take it after meals. It is cost-effective, lasting a long time, so I highly recommend it!
3.8
Gastritis aggravated
I regularly take this iron for seasonal anaemia, but my gastritis worsened, making it irritating. Although the absorption is poor with gastrointestinal issues, I continue with caution.
9.5
No gastric symptoms
These capsules are fantastic for iron deficiency anaemia. I take one daily without any gastric issues, unlike other iron supplements that caused me gastritis or constipation. After two weeks, my dizziness and hypotension symptoms improved significantly.
0
Stomach pain
Despite having gastritis and iron deficiency, this brand caused me significant stomach pain after just two pills, forcing me to stop.
8
Impact of Iron on Gastritis
We explored the effects of iron treatment on children diagnosed with collagenous gastritis (CG) and lymphocytic gastritis (LG). Over a period from 2000 to 2023, we reviewed cases that revealed a notable increase in diagnoses, highlighting the importance of awareness among healthcare providers.

Out of 31 children observed, iron deficiency anemia was present in 22 of them. The study showed that iron supplementation was commonly used, with 77% of the children receiving it. Notably, we found that after treatment, hemoglobin levels normalized in most cases, indicating that iron may indeed play a significant role in managing anemia associated with these types of gastritis.

However, it's crucial to mention that 29% of the patients required additional iron supplementation even after their levels normalized. This suggests that while iron treatment can benefit those suffering from anemia due to gastritis, it may not completely resolve the underlying issues for everyone. We also noted that repeat endoscopies did not reveal any significant changes in gastric histopathology, which indicates that while the symptoms could improve with treatment, the condition itself might not necessarily change.

Ultimately, our findings encourage healthcare professionals to consider CG and LG more seriously in pediatric patients, especially when treating related conditions like iron deficiency anemia.
9.5
We examined a case involving an 11-year-old male who experienced adverse effects from taking oral ferrous sulfate tablets to treat iron deficiency anemia. Over two months of treatment, he developed gastritis, which was confirmed through histological analysis during an endoscopy.

The findings revealed iron deposits in the stomach lining, prompting a reassessment of his iron supplementation strategy. We switched him from tablets to a liquid form of iron, which seemed to be gentler on his system.

After four months, a repeat endoscopy indicated a remarkable improvement, with the histological signs of gastritis resolving. This case illustrates that while iron is necessary for treating anemia, the form in which it's administered can significantly impact side effects like gastritis.
In our exploration of how iron treatment relates to collagenous gastritis (CG) in children, we found that this condition can lead to symptoms like abdominal pain and significant anemia. Over five years, we reviewed the cases of three young patients diagnosed with CG. They all struggled with iron deficiency anemia and experienced varying levels of abdominal discomfort alongside their other symptoms.

Initially, we prescribed oral iron supplements to these patients. Unfortunately, they didn’t respond well due to problems with tolerance, primarily because the supplements intensified their epigastric pain. As a result, we shifted our approach to ferric carboxymaltose (FCM) infusions, which proved effective. This treatment led to noticeable improvements in their anemia and overall well-being.

Overall, our findings highlighted that while oral iron may not always be the best option for children with CG, FCM infusion offered a promising alternative. We did notice that there were no adverse effects with this method, making it a viable option for managing iron deficiency in these patients. Moreover, we found that consistent and supportive care is crucial, as specific treatments still lack established effectiveness in the literature.

References

  1. Pinis M, Ziv-Sokolovskaya N, Kori M. Collagenous and lymphocytic gastritis in pediatric patients. A single-center experience observing an increase in diagnosis in recent years. Scand J Gastroenterol. 2024;59:1144. doi:10.1080/00365521.2024.2395858
  2. Chen CB, Chugh S, Rao D. Iron Pill-Induced Gastritis in a Pediatric Patient Taking Ferrous Sulfate Tablets. J Pediatr Pharmacol Ther. 2024;29:425. doi:10.5863/1551-6776-29.4.425
  3. Rogez J, Urbanski G, Vinatier E, Lavigne C, Emmanuel L, et al. Iron deficiency in pernicious anemia: Specific features of iron deficient patients and preliminary data on response to iron supplementation. Clin Nutr. 2024;43:1025. doi:10.1016/j.clnu.2024.03.011
  4. Isoldi S, Viola F, Cucchiara S, Dilillo A, Iorfida D, et al. Management of collagenous gastritis in children: Case series and literature review. Indian J Gastroenterol. 2024;43:567. doi:10.1007/s12664-023-01472-3
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