Overview

SCIENTIFIC SCORE
Possibly Effective
Based on 1 Research
7
USERS' SCORE
Moderately Good
Based on 21 Reviews
7.3
Supplement Facts
Serving Size: 1 Vegetable Capsule
Amount Per Serving
%DV
Iron (as iron bisglycinate chelate†)
25 mg
139%

Top Medical Research Studies

7
Iron treatment improves leg cramps
We explored the effects of iron deficiency (ID) in patients on maintenance hemodialysis, especially regarding common symptoms like leg cramps. The study included 154 patients, all of whom had reached target hemoglobin levels, which means they were not anemic. This allowed us to focus on the impact of ID without the confounding factor of low hemoglobin.

Our findings revealed that patients with iron deficiency reported a higher severity of leg cramps compared to those without ID. Specifically, we observed that a low transferrin saturation (TSAT) level contributed significantly to the experience of pain during vascular access punctures and those annoying intradialytic leg cramps. Additionally, patients with lower ferritin levels faced more intense issues like severe fatigue and headaches during their dialysis sessions.

The results suggest that treating iron deficiency could potentially alleviate these critical symptoms, indicating that proactive iron supplementation may be beneficial for those undergoing maintenance dialysis. Addressing ID might not only improve hemoglobin levels but also enhance overall quality of life by reducing painful experiences like leg cramps.
Read More

Most Useful Reviews

9.5
Reduced symptoms
Since I started taking this, my symptoms of restless legs have greatly decreased. After struggling with it for years, I noticed almost no symptoms now. My legs would feel itchy at times, but after starting this supplement, my condition improved rapidly. I now only take it a few times a week to keep the symptoms at bay. I'm very grateful for this product.
Read More
9.5
Improved energy
This iron supplement is fantastic! It didn't irritate my stomach and I've noticed my energy levels rise dramatically. I had been feeling weak and had leg cramps, but now I feel great. It's been a month, and my ferritin levels have improved significantly. I plan to continue taking it for even better results.
Read More
8.8
Relieved leg cramps
After taking one capsule daily for two months, my ferritin improved from 5.89 to 22.8 ng/ml. I noticed I had fewer leg cramps at night and felt less dizzy in the mornings. I’ve found taking it without dairy helps, and I appreciate the benefits it's provided.
Read More

Medical Researches

SCIENTIFIC SCORE
Possibly Effective
Based on 1 Research
7
  • All Researches
7
Iron treatment improves leg cramps
We explored the effects of iron deficiency (ID) in patients on maintenance hemodialysis, especially regarding common symptoms like leg cramps. The study included 154 patients, all of whom had reached target hemoglobin levels, which means they were not anemic. This allowed us to focus on the impact of ID without the confounding factor of low hemoglobin.

Our findings revealed that patients with iron deficiency reported a higher severity of leg cramps compared to those without ID. Specifically, we observed that a low transferrin saturation (TSAT) level contributed significantly to the experience of pain during vascular access punctures and those annoying intradialytic leg cramps. Additionally, patients with lower ferritin levels faced more intense issues like severe fatigue and headaches during their dialysis sessions.

The results suggest that treating iron deficiency could potentially alleviate these critical symptoms, indicating that proactive iron supplementation may be beneficial for those undergoing maintenance dialysis. Addressing ID might not only improve hemoglobin levels but also enhance overall quality of life by reducing painful experiences like leg cramps.
Read More

User Reviews

USERS' SCORE
Moderately Good
Based on 21 Reviews
7.3
  • All Reviews
  • Positive Reviews
  • Negative Reviews
9.5
Reduced symptoms
Since I started taking this, my symptoms of restless legs have greatly decreased. After struggling with it for years, I noticed almost no symptoms now. My legs would feel itchy at times, but after starting this supplement, my condition improved rapidly. I now only take it a few times a week to keep the symptoms at bay. I'm very grateful for this product.
Read More
9.5
Improved energy
This iron supplement is fantastic! It didn't irritate my stomach and I've noticed my energy levels rise dramatically. I had been feeling weak and had leg cramps, but now I feel great. It's been a month, and my ferritin levels have improved significantly. I plan to continue taking it for even better results.
Read More
8.8
Relieved leg cramps
After taking one capsule daily for two months, my ferritin improved from 5.89 to 22.8 ng/ml. I noticed I had fewer leg cramps at night and felt less dizzy in the mornings. I’ve found taking it without dairy helps, and I appreciate the benefits it's provided.
Read More
9.5
Leg cramps alleviated
I was pleasantly surprised by this iron supplement! It’s very gentle on my stomach, and, most importantly, my legs no longer feel numb. I'm truly impressed with its effectiveness.
Read More
9.5
Effective for fatigue
These capsules have truly helped with my iron deficiency, alleviating fatigue and leg cramps. I started taking them just before my period, and the improvements were noticeable. I feel like a different person!
Read More

Frequently Asked Questions

Leg cramps, often referred to as "charley horses," are sudden, involuntary contractions of one or more muscles in the leg. They typically occur in the calf muscles but can also affect the thighs and feet. These cramps can be quite painful and may last from a few seconds to several minutes. While the exact cause of leg cramps is not always clear, they can be triggered by factors such as dehydration, prolonged sitting or standing, electrolyte imbalances, or physical activity, especially in those who are not used to vigorous exercise.

Treatment for leg cramps often involves stretching the affected muscle gently, applying heat or cold to the area, and ensuring adequate hydration. For some, dietary adjustments to include more potassium, magnesium, and calcium may help prevent future occurrences. If cramps are frequent or severely debilitating, it may be beneficial to consult a healthcare provider for a more tailored approach. Understanding the underlying causes of leg cramps can lead to more effective management strategies, improving overall comfort and mobility.

Iron is a chemical element with the symbol Fe, derived from the Latin word "ferrum." It is a metal that is known for its strength and versatility, making it one of the most widely used materials in construction, manufacturing, and various industrial applications. Iron is the fourth most abundant element in the universe by mass and is primarily obtained through the mining of iron ores, such as hematite and magnetite. Once mined, it undergoes processes like smelting and refining to produce usable forms like cast iron, wrought iron, and steel.

In addition to its industrial uses, iron is also crucial for human health, as it plays a significant role in the production of hemoglobin, the protein in red blood cells responsible for transporting oxygen throughout the body. A deficiency in iron can lead to anemia, characterized by fatigue and weakened immunity. Overall, iron is a fundamental element that supports modern infrastructure and is vital for maintaining good health.

When it comes to leg cramps, the role of iron isn't straightforward. Iron is a crucial mineral that supports many bodily functions, including oxygen transport in the blood and energy metabolism. A deficiency in iron can lead to issues such as anemia, which may result in fatigue and weakness. While some people report experiencing leg cramps as part of their symptoms when iron levels are low, there isn't substantial evidence linking iron supplementation directly to preventing or alleviating leg cramps.

Instead, leg cramps are more commonly associated with factors such as dehydration, muscle fatigue, and electrolyte imbalances, particularly of potassium, calcium, and magnesium. If you're experiencing frequent leg cramps, it is advisable to stay well-hydrated, ensure you're incorporating a balanced diet rich in essential minerals, and consider stretching and strengthening exercises. If you suspect you have an iron deficiency or if cramps persist, consulting a healthcare professional is a prudent step.

Based on user reviews, the timeline for experiencing relief from leg cramps after starting this supplement can vary, but many users report noticeable improvements within a few weeks to a couple of months. For instance, one user mentioned experiencing a significant reduction in leg cramps after one month of use ((Read Review)). Another user noted that after taking the supplement daily for two months, not only did they see an increase in ferritin levels, but they also experienced fewer leg cramps at night ((Read Review)).

Overall, results seem to range from a few weeks to several months, with many users emphasizing that consistency in taking the supplement is key to achieving the best outcomes. The positive feedback suggests that while some may see results sooner, most users experience relief after a month or longer, highlighting individual differences in response ((Read Review)).

Recent research highlights the potential benefits of addressing iron deficiency (ID) for alleviating leg cramps, particularly in specific patient populations such as those undergoing maintenance hemodialysis. A study conducted with 154 hemodialysis patients monitored the impact of ID on various symptoms, including leg cramps. The findings indicated that patients with low transferrin saturation levels experienced more severe leg cramps compared to their counterparts with adequate iron levels. This suggests a significant link between addressing iron deficiency and the reduction of leg cramps, demonstrating that iron supplementation might play a crucial role in improving patient well-being by mitigating symptoms associated with leg cramps [1].

While this study specifically focused on hemodialysis patients, it raises questions about the broader implications of ID on leg cramps in the general population. However, additional research is necessary to establish a direct correlation and to determine if iron supplementation could universally benefit individuals suffering from leg cramps not related to dialysis. Therefore, while this research supports the idea that iron supplementation could help those with iron deficiency, more studies are needed to confirm its effectiveness across different demographics not receiving dialysis.

According to user reviews, many individuals have reported significant improvements in their symptoms after starting this iron supplement. For example, one user noted a dramatic decrease in symptoms of restless legs, stating that after years of struggling, they now experience almost no symptoms and only take the supplement a few times a week to maintain relief ((Read Review)). Several others have praised the product for alleviating leg cramps, with one user experiencing fewer episodes at night after consistent usage over two months ((Read Review)).

Moreover, users have reported increased energy levels and reduced feelings of dizziness after using the supplement. One user highlighted that after just a month of use, they felt a dramatic improvement in their overall well-being and mentioned a significant boost in ferritin levels as a key benefit ((Read Review)). While individual results can vary widely, the overall sentiment reflects a positive trend among users who have benefited from the iron supplement, with many emphasizing its gentle impact on the stomach compared to other options ((Read Review)).

Based on user reviews, many individuals report positive experiences when combining this iron supplement with other supplements to alleviate leg cramps. One user mentioned that taking the iron supplement in conjunction with folic acid and vitamin C helped improve their health significantly without any gastrointestinal discomfort, allowing them to maintain a regimen that supports their overall well-being while managing symptoms of leg cramps ((Read Review)). Another user found success in combining this iron supplement with an additional iron source to maximize benefits, reporting improvements in ferritin levels and a reduction in leg cramps and numbness in extremities ((Read Review)).

Conversely, some users caution against the gastrointestinal side effects that can arise from combining supplements. A few reviews highlight adverse reactions such as severe cramps and diarrhea, indicating that individuals should be mindful when mixing this iron supplement with others ((Read Review); (Read Review)). Therefore, while combining this supplement might enhance its effects, especially on leg cramps, individual tolerance can vary, making it essential to monitor any negative reactions closely.

Based on user reviews, there seems to be a consensus that an effective dose for iron can significantly mitigate leg cramps and other symptoms associated with iron deficiency. Many users report improvement in their condition after taking one capsule daily for an extended period. For instance, one reviewer noted that after two months of daily supplementation, they experienced a reduction in night leg cramps alongside improved ferritin levels (Read Review). Others similarly noted that consistent use led to a marked improvement in overall symptoms, emphasizing the importance of maintaining an appropriate dosage over time to achieve benefits (Read Review).

However, experiences vary greatly among users. While some achieved excellent results and reported no gastrointestinal discomfort, others mentioned adverse reactions such as abdominal pain, cramps, and diarrhea (review id='bb0bea77-63a1-4c7f-a903-cd8bdcda49ae', review id='4ab3b324-dcc5-4649-ac88-07cdcbc72c98'). Additionally, one user indicated that combining iron with another source was necessary to achieve an acceptable ferritin level without side effects (Read Review). Therefore, while a daily capsule appears to be beneficial for many, it is recommended to monitor individual tolerance and consult with a healthcare professional for personalized guidance.

8.8
Dizziness reduced
At 47, I often experienced dizziness and leg cramps but this supplement has greatly improved my condition. After a month of use, I noticed a significant reduction in symptoms and plan to continue taking it with my daughter.
8.8
Relieved leg cramps
After taking one capsule daily for two months, my ferritin improved from 5.89 to 22.8 ng/ml. I noticed I had fewer leg cramps at night and felt less dizzy in the mornings. I’ve found taking it without dairy helps, and I appreciate the benefits it's provided.
9.5
Hemoglobin boost
After experiencing leg cramps and low hemoglobin, this iron supplement has worked wonders. I felt a significant improvement within months, and I'm amazed at how it boosted my levels. Highly recommend it!
9.5
Reduced symptoms
Since I started taking this, my symptoms of restless legs have greatly decreased. After struggling with it for years, I noticed almost no symptoms now. My legs would feel itchy at times, but after starting this supplement, my condition improved rapidly. I now only take it a few times a week to keep the symptoms at bay. I'm very grateful for this product.
9.5
Improved energy
This iron supplement is fantastic! It didn't irritate my stomach and I've noticed my energy levels rise dramatically. I had been feeling weak and had leg cramps, but now I feel great. It's been a month, and my ferritin levels have improved significantly. I plan to continue taking it for even better results.
8.8
No more cramps
After taking this supplement, I’ve found relief from leg cramps and fatigue. It hasn’t caused any stomach issues like other iron medications, and I plan to purchase it again soon.
9.5
Improved health
I regularly drink iron for my anaemia. This product does not adversely affect my gastrointestinal tract; after two weeks, I had no complaints. My health improved significantly, with no dizziness, weakness, or leg cramps during cardio workouts. Overall, it's a really good product with no obvious side effects. I consume it with folic acid and vitamin C.
6.3
Low ferritin help
This iron supplement was prescribed by a reproductive specialist for low ferritin while planning for pregnancy. I initially took a small dosage, but my ferritin levels dropped. I now combine it with another iron source, which has started to improve my ferritin, and I no longer experience leg cramps or numbness in my extremities.
2.5
Gastrointestinal issues
I’ve tried many iron supplements, but this one caused an exceptionally bad reaction. Just one pill led to hellish cramps and diarrhoea. It's possibly not suitable for everyone, so be cautious.
0
Unpleasant effects
I took this for several days, but it led to diarrhoea, bloating, and severe cramps. Nothing alleviated the symptoms.
7
Iron treatment improves leg cramps
We explored the effects of iron deficiency (ID) in patients on maintenance hemodialysis, especially regarding common symptoms like leg cramps. The study included 154 patients, all of whom had reached target hemoglobin levels, which means they were not anemic. This allowed us to focus on the impact of ID without the confounding factor of low hemoglobin.

Our findings revealed that patients with iron deficiency reported a higher severity of leg cramps compared to those without ID. Specifically, we observed that a low transferrin saturation (TSAT) level contributed significantly to the experience of pain during vascular access punctures and those annoying intradialytic leg cramps. Additionally, patients with lower ferritin levels faced more intense issues like severe fatigue and headaches during their dialysis sessions.

The results suggest that treating iron deficiency could potentially alleviate these critical symptoms, indicating that proactive iron supplementation may be beneficial for those undergoing maintenance dialysis. Addressing ID might not only improve hemoglobin levels but also enhance overall quality of life by reducing painful experiences like leg cramps.

References

  1. Motonishi S, Tanaka K, Ozawa T. Iron deficiency associates with deterioration in several symptoms independently from hemoglobin level among chronic hemodialysis patients. PLoS One. 2018;13:e0201662. doi:10.1371/journal.pone.0201662
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