Solgar L-Lysine

We explored the effects of G2 lysine dendrimer on acne and how it can help restore balance to our skin microbiome. Acne is a persistent skin condition that brings about discomfort and concerns for many. Traditional treatments can often lose their effectiveness over time or lead to unwanted side effects. So, our goal was to see if this new approach could offer a gentler solution.

Our focus was on how G2 dendrimer specifically targets the troublesome bacteria associated with acne while preserving the healthy bacteria we rely on for healthy skin. Through our studies, we found that G2 dendrimer notably reduced inflammatory markers linked to acne, such as IL-8. What’s more, it didn’t harm the beneficial bacteria on the skin, which is essential for maintaining overall skin health.

We also conducted comparisons with standard over-the-counter treatments. The G2 dendrimer showed promising results in both limiting acne outbreaks and supporting the survival of good bacteria. Through metagenomic analysis, we confirmed that using G2 in a cosmetic product can effectively help rebalance the acne-prone microbiota without disrupting the friendly bacteria.

Overall, these findings highlight the potential of G2 lysine dendrimer as a non-aggressive option for acne prevention while respecting our skin's natural microbiome.

8.8

Gradual acne improvement

Most Useful Review

Yup, it helps! Not an immediate solution, but I noticed significant improvement in the frequency and size of my acne. After starting L-lysine, my hyperpigmentation is also improving.

Rash details

Improved skin condition

Most Useful Review

Rejuvenates! I take it alongside L-proline from the same company, and my skin condition has genuinely improved. I need to take it continuously but have breaks for two months. I also supplement this with niacin (vitamin B3), vitamin D3, and omega-3. Additionally, I take artichoke on an empty stomach for liver support, and inositol can also be beneficial. My skin feels and looks as if I've been to a beautician: nourished, elastic, smooth, with no rashes, just velvety skin! If you find my insights valuable for personal use, please click yes.

Autoimmune Disorder details

SCIENTIFIC SCORE

Moderately Effective

Based on 2 Researches

RCI001 shows promise for Sjögren syndrome

Efficacy of RCI001 as a Therapeutic Candidate in a Primary Sjögren Syndrome Mouse Model.

Most Relevant Research

We investigated how RCI001 can help mice with primary Sjögren syndrome. Eight 12-week-old NOD.B10-H2b mice were divided into two groups, one receiving RCI001 and the other a control treatment.

After one week, we noted significant improvements in eye health and tear secretion for the RCI group. They also showed reduced levels of inflammatory markers compared to those treated with the control. Overall, RCI001 proved to effectively reduce inflammation and oxidative stress, suggesting a promising therapeutic option for this autoimmune disease.

9.5

Herpes suppression

Most Useful Review

Lysine is essential for those with an autoimmune disorder like herpes. It prevents the virus from multiplying, greatly reducing outbreaks. After three months of 1000 mg daily, my herpes stopped appearing, even after minor colds or stress. It’s been a year now without any symptoms. I recommend this to friends and family suffering from herpes.

Cold exposure accelerates lysine catabolism to promote cold acclimation via remodeling hepatic histone crotonylation.

Most Relevant Research

We set out to uncover how certain amino acids, particularly lysine, help with cold acclimation. Over three months, 20 men were monitored for physiological changes after being exposed to cold.

We found that continuous exposure led to faster cold-induced vasodilation and improved finger temperature. Notably, lysine was the only amino acid that significantly changed and positively correlated with these improvements in cold response.

In mouse trials, lysine supplementation helped maintain core body temperature during cold exposure, indicating its role in supporting metabolic adjustments to the cold.

Speeds healing

Most Useful Review

This product speeds up the healing time for cold sores. My girlfriend, who has struggled with them her entire life, recently had one forming. After taking a tablet daily, her sore is in its last stages and did not fully develop. She highly recommends it to anyone who feels a cold sore coming on.

Allergies details

Eases allergic reactions

Most Useful Review

I have been using this product for a long time; it helped my mum get rid of allergies and eases my allergic reactions. Friends who drink it found it helpful in controlling herpes.

Anxiety details

Anxiety reduction observed with lysine

Anxiolytic, anti-nociceptive and body weight reducing effects of L-lysine in rats: Relationship with brain serotonin an In-Vivo and In-Silico study.

Most Relevant Research

We investigated how L-lysine, an essential amino acid, influences anxiety and body weight. The study involved administering two doses of L-lys to rats over 20 days.

We found that while L-lys didn't affect food intake, it did lead to weight reduction and showed signs of anxiolytic effects on the first day. Notably, repeated doses increased serotonin levels in key brain areas, which may explain its calming effects.

However, the study's outcomes indicate that L-lys may not dramatically alter anxiety compared to other treatments.

9.5

Helps with anxiety

Most Useful Review

Perfectly! I take it on an empty stomach before meals. Lysine supplementation can assist those who are depressed and relieve anxiety and stress symptoms.

Cold Sores details

SCIENTIFIC SCORE

Questionable

Based on 6 Researches

Lysine helps reduce cold sore outbreaks

Lysine as a prophylactic agent in the treatment of recurrent herpes simplex labialis.

Most Relevant Research

We examined the effectiveness of long-term lysine supplementation for preventing cold sores, specifically in individuals with a history of frequent outbreaks. Over a 12-month period, twenty-six volunteers participated in a double-blind study, taking daily doses of 1,000 mg of lysine.

Our findings indicated that those taking lysine experienced significantly fewer lesions compared to the control group. Moreover, when participants stopped the supplementation, their outbreaks increased. Maintaining serum lysine levels above 165 nmol/ml appeared crucial for effectiveness, highlighting lysine's potential benefits in managing recurrent cold sores.

Herpes treatment

Most Useful Review

Lysine is essential for those who suffer from herpes, preventing the virus from multiplying. After taking 1000 mg daily for three months, my herpes stopped appearing, even after colds or stress. It's been a year without any outbreaks. I recommend it to friends and family with herpes.

Ear Infection details

Sinus issues resolved

Most Useful Review

SINUS ISSUES ARE GONE!!! Initially, I started taking this product for my acne and was surprised to find it also worked wonders on my chronic sinus issues. I no longer suffer from sinus pain, congestion, headaches, or infections. I stopped for three days, and the problems resurfaced, proving this product is truly effective.

Shingles details

Lysine improves herpes symptoms

Subjective response to lysine in the therapy of herpes simplex.

Most Relevant Research

We explored the effectiveness of lysine supplementation in treating herpes infections through a survey of 1,543 participants after a six-month trial. The findings revealed that a substantial 84% reported that lysine helped prevent recurrences or reduced the frequency of outbreaks.

Notably, only 8% of users described their symptoms as severe while taking lysine, compared to 79% who felt that way without it. Healing times improved significantly; 83% felt lesions healed in five days or less with lysine, while 90% said healing took longer without it. Overall, 88% regarded lysine as an effective treatment.

9.5

Health improvement

Most Useful Review

I experienced shingles seven times in four years. A new holistic dentist advised me to take L-lysine. After following his guidance of 1000 mg daily and up to 3000 mg during stress or illness, I have not had further shingles episodes, and my health has improved significantly. I highly endorse this product based on my experience.

Herpes details

Breakout-free success

Most Useful Review

No more herpes breakouts! I'm amazed at this supplement! I've re-ordered multiple times and don’t want to be without it. I previously had prescribed medication for outbreaks but disliked long-term use. I started taking Lysine after seeing it could help herpes breakouts. Initially one tablet didn’t suffice, but I increased to two daily—it worked! I've been breakout-free for months now and would highly recommend it!

Ulcer details

Canker sores eliminated

Most Useful Review

I ordered this to prevent canker sores, which plague me after two decades. This product came securely packaged, and thankfully, it literally reversed a canker sore overnight! I take 200mg daily and have eliminated nuts from my diet to enhance its effectiveness.

Bone Pain details

SCIENTIFIC SCORE

Likely Very Effective

Effectiveness of lysine on bone pain

[The effects of the carbocalcitonin + arginine-lysine-lactose combination in senile involutional osteoporosis].

Most Relevant Research

We examined the effects of an arginine-lysine-lactose combination on bone pain in older adults with osteoporosis. In our study of 40 participants, we compared those receiving this treatment to a control group receiving carbocalcitonin alone.

After six months, we observed that the group treated with arginine-lysine-lactose showed greater improvements, including increased bone density and reduced pain. These benefits likely stem from enhanced calcium absorption linked to lysine and lactose.

Overall, the combination proved effective in alleviating bone pain symptoms associated with aging.

9.5

Pain relief

Most Useful Review

This product is essential for when I have aphthae and sores in my mouth. It significantly reduces my pain level and helps speed up recovery. There is no substitute for this remedy in treating bone pain.

Chronic Fatigue Syndrome details

On the advice of a doctor, I have been taking Lizin for a month. I noticed a significant improvement during the illness season. My fatigue and drowsiness have vanished, and I now feel more physically resilient, not at all like a sluggish bear awakened from hibernation, but rather lively.

Depression details

Lysine is an essential amino acid that must be obtained from food or supplements. It aids athletes in muscle recovery, supports skin and hair health, and helps those prone to depression. It also assists the elderly in preventing osteoporosis and those suffering from herpes in mitigating symptoms.

Osteoporosis details

SCIENTIFIC SCORE

Moderately Effective

Based on 3 Researches

NSD2 inhibition may reduce osteoporosis

NSD2-mediated H3K36me2 exacerbates osteoporosis via activation of hoxa2 in bone marrow mesenchymal stem cells.

Most Relevant Research

We explored the connection between NSD2 and bone health, specifically how it affects bone marrow stem cells in osteoporosis. By using advanced techniques, we found that NSD2 inhibits the growth of these cells, which is crucial for healthy bones.

In animal models of osteoporosis, blocking NSD2 not only promoted stem cell differentiation but also helped prevent bone loss. Our findings suggest that targeting NSD2 could be a new way to treat osteoporosis and improve bone health.

Reduces viral load

Most Useful Review

With consistently low neutrophil levels, this helps reduce the viral load in my body. I take it as emergency support for herpes. Additionally, lysine is beneficial for osteoporosis, aiding in calcium absorption and its transport to bone tissue.