Overview

SCIENTIFIC SCORE
Likely Very Effective
Based on 1 Research
9
USERS' SCORE
Good
Based on 37 Reviews
8.3
Supplement Facts
Serving Size: 1 Vegetable Capsule
Amount Per Serving
%DV
L-Lysine (as L-lysine HCl) (Free Form)
500 mg
**

Top Medical Research Studies

9
Lysine aids cold adaptation mechanisms
We set out to uncover how certain amino acids, particularly lysine, help with cold acclimation. Over three months, 20 men were monitored for physiological changes after being exposed to cold.

We found that continuous exposure led to faster cold-induced vasodilation and improved finger temperature. Notably, lysine was the only amino acid that significantly changed and positively correlated with these improvements in cold response.

In mouse trials, lysine supplementation helped maintain core body temperature during cold exposure, indicating its role in supporting metabolic adjustments to the cold.
Read More

Most Useful Reviews

8
Speeds healing
69 people found this helpful
This product speeds up the healing time for cold sores. My girlfriend, who has struggled with them her entire life, recently had one forming. After taking a tablet daily, her sore is in its last stages and did not fully develop. She highly recommends it to anyone who feels a cold sore coming on.
Read More
10
Miraculous effect
32 people found this helpful
This product is nothing short of miraculous! I woke up with what appeared to be a cold sore and immediately ordered lysine. I took several tablets since then, and this morning there was nothing! My lips are now soft and hydrated. I can't believe how well it works!
Read More
8
Helps with colds
19 people found this helpful
It helps me; I drink it in courses. It aids with frequent colds on the lips!
Read More

Medical Researches

SCIENTIFIC SCORE
Likely Very Effective
Based on 1 Research
9
  • All Researches
9
Lysine aids cold adaptation mechanisms
We set out to uncover how certain amino acids, particularly lysine, help with cold acclimation. Over three months, 20 men were monitored for physiological changes after being exposed to cold.

We found that continuous exposure led to faster cold-induced vasodilation and improved finger temperature. Notably, lysine was the only amino acid that significantly changed and positively correlated with these improvements in cold response.

In mouse trials, lysine supplementation helped maintain core body temperature during cold exposure, indicating its role in supporting metabolic adjustments to the cold.
Read More

User Reviews

USERS' SCORE
Good
Based on 37 Reviews
8.3
  • All Reviews
  • Positive Reviews
  • Negative Reviews
8
Speeds healing
69 people found this helpful
This product speeds up the healing time for cold sores. My girlfriend, who has struggled with them her entire life, recently had one forming. After taking a tablet daily, her sore is in its last stages and did not fully develop. She highly recommends it to anyone who feels a cold sore coming on.
Read More
10
Miraculous effect
32 people found this helpful
This product is nothing short of miraculous! I woke up with what appeared to be a cold sore and immediately ordered lysine. I took several tablets since then, and this morning there was nothing! My lips are now soft and hydrated. I can't believe how well it works!
Read More
8
Helps with colds
19 people found this helpful
It helps me; I drink it in courses. It aids with frequent colds on the lips!
Read More
9
Stops cold sore outbreaks
9 people found this helpful
Wonderful! Great for cold sore outbreaks! I take 2000mg at the first sign (tingle, but no visible sore) and do this 2-3 times a day. In a couple of days, it's gone! Many others I know also take it at the first sign of a cold or sore throat, as it works well to stop it in its tracks. You must start right at the first signs of illness and ensure you take enough and often for it to be effective.
Read More
9
Effective relief
7 people found this helpful
I have had problems around my lips since 2012, including cold sores. Many products failed to help until I found this. After taking it, my cold sores have nearly vanished within a day. I am very impressed and it saved me a trip to the doctors.
Read More

Frequently Asked Questions

9
Prevents cold sores
2 people found this helpful
Excellent for cold sores. Great product! I took about four or five capsules when I felt an attack coming on, and fortunately, the cold sore didn't break out! Awesome!
9
Quick recovery
Excellent! I saw during a cold that the effect was remarkable; it puts you on your feet in just three days. I took two capsules at night.
9
Long-term use
Excellent! I have taken this for over ten years, and it has been very helpful against cold sores. Best L-Lysine available. I love the Solgar brand; daily use has helped significantly against cold sores. I take two capsules in the morning.
9
Lysine aids cold adaptation mechanisms
We set out to uncover how certain amino acids, particularly lysine, help with cold acclimation. Over three months, 20 men were monitored for physiological changes after being exposed to cold.

We found that continuous exposure led to faster cold-induced vasodilation and improved finger temperature. Notably, lysine was the only amino acid that significantly changed and positively correlated with these improvements in cold response.

In mouse trials, lysine supplementation helped maintain core body temperature during cold exposure, indicating its role in supporting metabolic adjustments to the cold.

References

  1. Xue C, Zhu S, Li Y, Chen X, Lu L, et al. Cold exposure accelerates lysine catabolism to promote cold acclimation via remodeling hepatic histone crotonylation. Environ Int. 2024;192:109015. doi:10.1016/j.envint.2024.109015
image