' 
SCIENTIFIC SCORE
Likely Very Effective
Based on 1 Research
9
USERS' SCORE
Good
Based on 18 Reviews
8.8
Supplement Facts
Serving Size: 1 Vegetable Capsule
Amount Per Serving
%DV
L-Lysine (as L-lysine HCl) (Free Form)
500 mg
**
Top Medical Research Studies
9
Lysine aids cold adaptation
Cold exposure accelerates lysine catabolism to promote cold acclimation via remodeling hepatic histone crotonylation.
Direct examination of lysine impact
We focused on understanding how lysine, an essential amino acid, plays a role in cold acclimation. Our study involved twenty male participants who underwent three months of natural cold exposure, during which we measured cold-induced vasodilation (CIVD) and analyzed plasma amino acid levels.
After the three-month cold exposure, we observed that continuous exposure led to quicker CIVD responses and better finger temperature regulation. Notably, we found decreases in plasma levels of lysine and glycine in both humans and mice. Lysine emerged as the key amino acid showing significant changes that correlated strongly with improved CIVD outcomes.
To delve deeper, we conducted an experiment where mice were given lysine supplements during a week of cold exposure. These mice maintained higher core and surface temperatures, indicating a protective effect against cold. Additionally, lysine supplementation seemed to promote certain liver functions by increasing levels of specific histones and gene expressions related to metabolism.
Overall, our findings highlight lysine not only as a critical player in adapting to cold conditions but also suggest its potential importance for metabolic health during such challenges.
After the three-month cold exposure, we observed that continuous exposure led to quicker CIVD responses and better finger temperature regulation. Notably, we found decreases in plasma levels of lysine and glycine in both humans and mice. Lysine emerged as the key amino acid showing significant changes that correlated strongly with improved CIVD outcomes.
To delve deeper, we conducted an experiment where mice were given lysine supplements during a week of cold exposure. These mice maintained higher core and surface temperatures, indicating a protective effect against cold. Additionally, lysine supplementation seemed to promote certain liver functions by increasing levels of specific histones and gene expressions related to metabolism.
Overall, our findings highlight lysine not only as a critical player in adapting to cold conditions but also suggest its potential importance for metabolic health during such challenges.
Read More
Most Useful Reviews
9
Speeds healing
This product speeds up the healing time for cold sores. My girlfriend, who has struggled with them her entire life, recently had one forming. After taking a tablet daily, her sore is in its last stages and did not fully develop. She highly recommends it to anyone who feels a cold sore coming on.
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10
Miraculous effect
This product is nothing short of miraculous! I woke up with what appeared to be a cold sore and immediately ordered lysine. I took several tablets since then, and this morning there was nothing! My lips are now soft and hydrated. I can't believe how well it works!
Read More
9.5
Stops cold sore outbreaks
Wonderful! Great for cold sore outbreaks! I take 2000mg at the first sign (tingle, but no visible sore) and do this 2-3 times a day. In a couple of days, it's gone! Many others I know also take it at the first sign of a cold or sore throat, as it works well to stop it in its tracks. You must start right at the first signs of illness and ensure you take enough and often for it to be effective.
Read More
Medical Researches
SCIENTIFIC SCORE
Likely Very Effective
Based on 1 Research
9
9
Lysine aids cold adaptation
Cold exposure accelerates lysine catabolism to promote cold acclimation via remodeling hepatic histone crotonylation.
Direct examination of lysine impact
We focused on understanding how lysine, an essential amino acid, plays a role in cold acclimation. Our study involved twenty male participants who underwent three months of natural cold exposure, during which we measured cold-induced vasodilation (CIVD) and analyzed plasma amino acid levels.
After the three-month cold exposure, we observed that continuous exposure led to quicker CIVD responses and better finger temperature regulation. Notably, we found decreases in plasma levels of lysine and glycine in both humans and mice. Lysine emerged as the key amino acid showing significant changes that correlated strongly with improved CIVD outcomes.
To delve deeper, we conducted an experiment where mice were given lysine supplements during a week of cold exposure. These mice maintained higher core and surface temperatures, indicating a protective effect against cold. Additionally, lysine supplementation seemed to promote certain liver functions by increasing levels of specific histones and gene expressions related to metabolism.
Overall, our findings highlight lysine not only as a critical player in adapting to cold conditions but also suggest its potential importance for metabolic health during such challenges.
After the three-month cold exposure, we observed that continuous exposure led to quicker CIVD responses and better finger temperature regulation. Notably, we found decreases in plasma levels of lysine and glycine in both humans and mice. Lysine emerged as the key amino acid showing significant changes that correlated strongly with improved CIVD outcomes.
To delve deeper, we conducted an experiment where mice were given lysine supplements during a week of cold exposure. These mice maintained higher core and surface temperatures, indicating a protective effect against cold. Additionally, lysine supplementation seemed to promote certain liver functions by increasing levels of specific histones and gene expressions related to metabolism.
Overall, our findings highlight lysine not only as a critical player in adapting to cold conditions but also suggest its potential importance for metabolic health during such challenges.
Read More
User Reviews
USERS' SCORE
Good
Based on 18 Reviews
8.8
10
Miraculous effect
This product is nothing short of miraculous! I woke up with what appeared to be a cold sore and immediately ordered lysine. I took several tablets since then, and this morning there was nothing! My lips are now soft and hydrated. I can't believe how well it works!
9.5
Effective relief
I have had problems around my lips since 2012, including cold sores. Many products failed to help until I found this. After taking it, my cold sores have nearly vanished within a day. I am very impressed and it saved me a trip to the doctors.
9.5
Reduces severity
Taking this l-lysine every day has been amazing. It fends off and seriously reduces the severity of any cold sore that decides to appear. I could not be without it; I've tried other brands but this one works best for me.
9.5
Effective for cold sores
Great for cold sores. Solgar is an excellent company, and I feel they are very committed to their customers. L-Lysine, in particular, by them is fantastic for cold sores. I am quite prone to them during the autumn and winter months, especially around my finals week for school. After reading about Lysine and its benefits, I decided to give this product a try. I do not take it daily, though I think it wouldn't be a bad idea. When I feel a cold sore coming on, I take 3-4 of these a day, which results in no cold sores for me. Love it!
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9.5
Stops cold sore outbreaks
Wonderful! Great for cold sore outbreaks! I take 2000mg at the first sign (tingle, but no visible sore) and do this 2-3 times a day. In a couple of days, it's gone! Many others I know also take it at the first sign of a cold or sore throat, as it works well to stop it in its tracks. You must start right at the first signs of illness and ensure you take enough and often for it to be effective.
Read More
