Reviewed By
Overview
SCIENTIFIC SCORE
Moderately Effective
Based on 4 Researches
8.3
USERS' SCORE
Medium or Average
Based on 9 Reviews
6.9
Supplement Facts
Serving Size: 3 Tablets
Amount Per Serving
%DV
Vitamin B6 (as pyridoxine HCl)
25 mg
1,471%
Magnesium (as magnesium oxide)
400 mg
95%
Top Medical Research Studies
9
We explored an intriguing connection between vitamin B6 and something called the Chinese Restaurant Syndrome, often linked to the consumption of monosodium L-glutamate (MSG). This study involved a group of 155 students who had not taken extra vitamin B6. By analyzing an enzyme called aspartate transaminase in their blood cells, we identified 27 individuals with notably low levels, which suggested they might have a vitamin B6 deficiency.
Among these 27 participants, we challenged them with glutamate and a placebo, where 12 recognized symptoms associated with the syndrome while 15 did not. Through a double-blind treatment over twelve weeks, we administered pyridoxine (a form of vitamin B6) and a placebo. After completing the treatment, we re-challenged them with glutamate.
We found that those who received pyridoxine showed a significant decrease in symptoms, proving treatment was effective for most of them. Specifically, only 3 of the 12 who received placebo experienced the symptoms again, while 8 of the 9 who had pyridoxine did not react to glutamate. Our results indicate a strong link between vitamin B6 levels and the management of symptoms tied to this syndrome, suggesting that vitamin B6 may play a critical role in enhancing our resilience against certain forms of food-related discomfort.
Among these 27 participants, we challenged them with glutamate and a placebo, where 12 recognized symptoms associated with the syndrome while 15 did not. Through a double-blind treatment over twelve weeks, we administered pyridoxine (a form of vitamin B6) and a placebo. After completing the treatment, we re-challenged them with glutamate.
We found that those who received pyridoxine showed a significant decrease in symptoms, proving treatment was effective for most of them. Specifically, only 3 of the 12 who received placebo experienced the symptoms again, while 8 of the 9 who had pyridoxine did not react to glutamate. Our results indicate a strong link between vitamin B6 levels and the management of symptoms tied to this syndrome, suggesting that vitamin B6 may play a critical role in enhancing our resilience against certain forms of food-related discomfort.
Read More
8
Magnesium oxide shows promise against EHEC
We investigated how a macroporous magnesium oxide-templated carbon (MgOC) could help combat Enterohemorrhagic E. coli (EHEC), a common foodborne threat. MgOC effectively adsorbed harmful Shiga toxins and secretory proteins that contribute to EHEC's virulence while not affecting the bacteria's growth itself. Notably, infected mice treated with MgOC showed an extended survival period. This innovative material didn't harm healthy cells or gut bacteria. However, it also absorbed several antimicrobial agents, suggesting it could be combined with specific antibiotics to improve treatment options against EHEC infections.
Read More
9
Pyridoxal phosphate may aid recovery
We explored the effects of vitamin B6 treatment in a fascinating case of ginkgo seed poisoning. A 2-year-old girl suffered from vomiting and diarrhea after consuming a large quantity of ginkgo seeds. The symptoms escalated to convulsions a few hours later, and blood tests revealed high levels of 4-metoxypyridoxine, a byproduct related to vitamin B6.
Reports indicate that ginkgo seed poisoning can lead to severe complications, particularly in children who may have repetitive seizures that can be fatal. However, in this case, the quick administration of pyridoxal phosphate, a form of vitamin B6, seemed to potentially prevent further seizures. This case also marks the first time that 4-metoxypyridoxine levels were measured in the context of ginkgo seed poisoning in an English-language report.
Overall, while the study did not conduct a formal evaluation of vitamin B6’s isolated effects, the results suggest that prompt treatment with pyridoxal phosphate can play a critical role in recovery from this type of food poisoning. Our findings highlight the importance of being aware of the risks associated with eating certain traditional foods and the potential benefits of timely medical intervention.
Reports indicate that ginkgo seed poisoning can lead to severe complications, particularly in children who may have repetitive seizures that can be fatal. However, in this case, the quick administration of pyridoxal phosphate, a form of vitamin B6, seemed to potentially prevent further seizures. This case also marks the first time that 4-metoxypyridoxine levels were measured in the context of ginkgo seed poisoning in an English-language report.
Overall, while the study did not conduct a formal evaluation of vitamin B6’s isolated effects, the results suggest that prompt treatment with pyridoxal phosphate can play a critical role in recovery from this type of food poisoning. Our findings highlight the importance of being aware of the risks associated with eating certain traditional foods and the potential benefits of timely medical intervention.
Read More
Most Useful Reviews
9
High blood pressure
4 people found this helpful
This magnesium, combined with taurine, has been very effective in managing my high blood pressure. My entire family uses it, and I’ve found better results compared to alternatives. After a month, I stopped needing my blood pressure pills—highly recommended!
Read More
9
Normalised heart activity
3 people found this helpful
Magnesium is essential for the normal functioning of the heart. After trying various domestic brands, I found that Evalar's magnesium was effective, providing immediate and noticeable results. It stabilised my condition associated with VSD, and my heart activity returned to normal. I take a couple of tablets daily with food. There are plenty in the container, so I believe it will last a long time.
Read More
9
Chemotherapy support
2 people found this helpful
This supplement is great for alleviating constipation caused by chemotherapy. My husband, a cancer patient, found relief without the harmful chemicals typically found in laxatives. The combination of magnesium with Vitamin B6 aids in absorption and improves his overall experience during treatment.
Read More
Medical Researches
SCIENTIFIC SCORE
Moderately Effective
Based on 4 Researches
8.3
- All Researches
9
Pyridoxal phosphate may aid recovery
We explored the effects of vitamin B6 treatment in a fascinating case of ginkgo seed poisoning. A 2-year-old girl suffered from vomiting and diarrhea after consuming a large quantity of ginkgo seeds. The symptoms escalated to convulsions a few hours later, and blood tests revealed high levels of 4-metoxypyridoxine, a byproduct related to vitamin B6.
Reports indicate that ginkgo seed poisoning can lead to severe complications, particularly in children who may have repetitive seizures that can be fatal. However, in this case, the quick administration of pyridoxal phosphate, a form of vitamin B6, seemed to potentially prevent further seizures. This case also marks the first time that 4-metoxypyridoxine levels were measured in the context of ginkgo seed poisoning in an English-language report.
Overall, while the study did not conduct a formal evaluation of vitamin B6’s isolated effects, the results suggest that prompt treatment with pyridoxal phosphate can play a critical role in recovery from this type of food poisoning. Our findings highlight the importance of being aware of the risks associated with eating certain traditional foods and the potential benefits of timely medical intervention.
Reports indicate that ginkgo seed poisoning can lead to severe complications, particularly in children who may have repetitive seizures that can be fatal. However, in this case, the quick administration of pyridoxal phosphate, a form of vitamin B6, seemed to potentially prevent further seizures. This case also marks the first time that 4-metoxypyridoxine levels were measured in the context of ginkgo seed poisoning in an English-language report.
Overall, while the study did not conduct a formal evaluation of vitamin B6’s isolated effects, the results suggest that prompt treatment with pyridoxal phosphate can play a critical role in recovery from this type of food poisoning. Our findings highlight the importance of being aware of the risks associated with eating certain traditional foods and the potential benefits of timely medical intervention.
Read More
9
We explored an intriguing connection between vitamin B6 and something called the Chinese Restaurant Syndrome, often linked to the consumption of monosodium L-glutamate (MSG). This study involved a group of 155 students who had not taken extra vitamin B6. By analyzing an enzyme called aspartate transaminase in their blood cells, we identified 27 individuals with notably low levels, which suggested they might have a vitamin B6 deficiency.
Among these 27 participants, we challenged them with glutamate and a placebo, where 12 recognized symptoms associated with the syndrome while 15 did not. Through a double-blind treatment over twelve weeks, we administered pyridoxine (a form of vitamin B6) and a placebo. After completing the treatment, we re-challenged them with glutamate.
We found that those who received pyridoxine showed a significant decrease in symptoms, proving treatment was effective for most of them. Specifically, only 3 of the 12 who received placebo experienced the symptoms again, while 8 of the 9 who had pyridoxine did not react to glutamate. Our results indicate a strong link between vitamin B6 levels and the management of symptoms tied to this syndrome, suggesting that vitamin B6 may play a critical role in enhancing our resilience against certain forms of food-related discomfort.
Among these 27 participants, we challenged them with glutamate and a placebo, where 12 recognized symptoms associated with the syndrome while 15 did not. Through a double-blind treatment over twelve weeks, we administered pyridoxine (a form of vitamin B6) and a placebo. After completing the treatment, we re-challenged them with glutamate.
We found that those who received pyridoxine showed a significant decrease in symptoms, proving treatment was effective for most of them. Specifically, only 3 of the 12 who received placebo experienced the symptoms again, while 8 of the 9 who had pyridoxine did not react to glutamate. Our results indicate a strong link between vitamin B6 levels and the management of symptoms tied to this syndrome, suggesting that vitamin B6 may play a critical role in enhancing our resilience against certain forms of food-related discomfort.
Read More
8
Magnesium oxide shows promise against EHEC
We investigated how a macroporous magnesium oxide-templated carbon (MgOC) could help combat Enterohemorrhagic E. coli (EHEC), a common foodborne threat. MgOC effectively adsorbed harmful Shiga toxins and secretory proteins that contribute to EHEC's virulence while not affecting the bacteria's growth itself. Notably, infected mice treated with MgOC showed an extended survival period. This innovative material didn't harm healthy cells or gut bacteria. However, it also absorbed several antimicrobial agents, suggesting it could be combined with specific antibiotics to improve treatment options against EHEC infections.
Read More
7
Vitamin B6 effects on mercury poisoning
We explored the effects of vitamin B6 in conjunction with D-penicillamine (DPA) as a treatment for methyl mercury poisoning in a study involving female rats. The research aimed to understand how this vitamin might support recovery during food poisoning caused by mercury exposure.
The study observed changes in food consumption and body weight as early indicators of methyl mercury toxicity, noting a significant 75% decrease in food intake within the first day. Interestingly, while DPA effectively prevented neurological symptoms and enhanced recovery, vitamin B6's specific impact on food poisoning was less clear. It appeared that DPA's positive effects could be counterbalanced by vitamin B6, as it sometimes reduced food consumption and body weight.
Overall, while DPA showed promise in mitigating the effects of methyl mercury, the role of vitamin B6 was not distinct enough to draw firm conclusions regarding its effectiveness. Therefore, we found that vitamin B6 did not significantly enhance treatment outcomes, emphasizing the complexity of using multiple interventions in managing food poisoning.
The study observed changes in food consumption and body weight as early indicators of methyl mercury toxicity, noting a significant 75% decrease in food intake within the first day. Interestingly, while DPA effectively prevented neurological symptoms and enhanced recovery, vitamin B6's specific impact on food poisoning was less clear. It appeared that DPA's positive effects could be counterbalanced by vitamin B6, as it sometimes reduced food consumption and body weight.
Overall, while DPA showed promise in mitigating the effects of methyl mercury, the role of vitamin B6 was not distinct enough to draw firm conclusions regarding its effectiveness. Therefore, we found that vitamin B6 did not significantly enhance treatment outcomes, emphasizing the complexity of using multiple interventions in managing food poisoning.
Read More
User Reviews
USERS' SCORE
Medium or Average
Based on 9 Reviews
6.9
- All Reviews
- Positive Reviews
- Negative Reviews
9
High blood pressure
4 people found this helpful
This magnesium, combined with taurine, has been very effective in managing my high blood pressure. My entire family uses it, and I’ve found better results compared to alternatives. After a month, I stopped needing my blood pressure pills—highly recommended!
Read More
9
Normalised heart activity
3 people found this helpful
Magnesium is essential for the normal functioning of the heart. After trying various domestic brands, I found that Evalar's magnesium was effective, providing immediate and noticeable results. It stabilised my condition associated with VSD, and my heart activity returned to normal. I take a couple of tablets daily with food. There are plenty in the container, so I believe it will last a long time.
Read More
9
Chemotherapy support
2 people found this helpful
This supplement is great for alleviating constipation caused by chemotherapy. My husband, a cancer patient, found relief without the harmful chemicals typically found in laxatives. The combination of magnesium with Vitamin B6 aids in absorption and improves his overall experience during treatment.
Read More
9
Improved digestion
This super food has a remarkable effect on digestion, helping me go to the toilet with ease. The improvement in my overall well-being after consuming it indicates its beneficial effects on the body.
Read More
6
Stress relief
5 people found this helpful
After starting Magnesium B6, I noticed a reduction in stress levels within a few days. This product is essential as magnesium aids in reducing stress, and it has noticeably improved my joint pain as well. I recommend this as both my husband and I use it daily and find it beneficial.
Read More
Frequently Asked Questions
9
High blood pressure
4 people found this helpful
This magnesium, combined with taurine, has been very effective in managing my high blood pressure. My entire family uses it, and I’ve found better results compared to alternatives. After a month, I stopped needing my blood pressure pills—highly recommended!
9
Normalised heart activity
3 people found this helpful
Magnesium is essential for the normal functioning of the heart. After trying various domestic brands, I found that Evalar's magnesium was effective, providing immediate and noticeable results. It stabilised my condition associated with VSD, and my heart activity returned to normal. I take a couple of tablets daily with food. There are plenty in the container, so I believe it will last a long time.
9
Chemotherapy support
2 people found this helpful
This supplement is great for alleviating constipation caused by chemotherapy. My husband, a cancer patient, found relief without the harmful chemicals typically found in laxatives. The combination of magnesium with Vitamin B6 aids in absorption and improves his overall experience during treatment.
2
Requires better form
1 people found this helpful
I saw no effect from this magnesium, which I bought for a family member over 50. The lack of impact may be due to the form of magnesium used in this supplement. I suggest trying chelated magnesium instead, as it’s better absorbed. It's also important to consume a diet rich in natural magnesium sources like green leafy vegetables, barley, oatmeal, avocados, and fish, as synthetic magnesium often fails to meet daily needs—typically providing only up to 20% of the required intake.
2
Digestibility issues
7 people found this helpful
I tried this magnesium as an alternative to Magne B6, unsure of magnesium forms. I've since learned that magnesium oxide is poorly absorbed and acts as a laxative. I encountered stomach issues and heartburn when taking the recommended dosage, leading me to stop using it altogether.
8
Magnesium oxide shows promise against EHEC
We investigated how a macroporous magnesium oxide-templated carbon (MgOC) could help combat Enterohemorrhagic E. coli (EHEC), a common foodborne threat. MgOC effectively adsorbed harmful Shiga toxins and secretory proteins that contribute to EHEC's virulence while not affecting the bacteria's growth itself. Notably, infected mice treated with MgOC showed an extended survival period. This innovative material didn't harm healthy cells or gut bacteria. However, it also absorbed several antimicrobial agents, suggesting it could be combined with specific antibiotics to improve treatment options against EHEC infections.
9
Pyridoxal phosphate may aid recovery
We explored the effects of vitamin B6 treatment in a fascinating case of ginkgo seed poisoning. A 2-year-old girl suffered from vomiting and diarrhea after consuming a large quantity of ginkgo seeds. The symptoms escalated to convulsions a few hours later, and blood tests revealed high levels of 4-metoxypyridoxine, a byproduct related to vitamin B6.
Reports indicate that ginkgo seed poisoning can lead to severe complications, particularly in children who may have repetitive seizures that can be fatal. However, in this case, the quick administration of pyridoxal phosphate, a form of vitamin B6, seemed to potentially prevent further seizures. This case also marks the first time that 4-metoxypyridoxine levels were measured in the context of ginkgo seed poisoning in an English-language report.
Overall, while the study did not conduct a formal evaluation of vitamin B6’s isolated effects, the results suggest that prompt treatment with pyridoxal phosphate can play a critical role in recovery from this type of food poisoning. Our findings highlight the importance of being aware of the risks associated with eating certain traditional foods and the potential benefits of timely medical intervention.
Reports indicate that ginkgo seed poisoning can lead to severe complications, particularly in children who may have repetitive seizures that can be fatal. However, in this case, the quick administration of pyridoxal phosphate, a form of vitamin B6, seemed to potentially prevent further seizures. This case also marks the first time that 4-metoxypyridoxine levels were measured in the context of ginkgo seed poisoning in an English-language report.
Overall, while the study did not conduct a formal evaluation of vitamin B6’s isolated effects, the results suggest that prompt treatment with pyridoxal phosphate can play a critical role in recovery from this type of food poisoning. Our findings highlight the importance of being aware of the risks associated with eating certain traditional foods and the potential benefits of timely medical intervention.
7
Vitamin B6 effects on mercury poisoning
We explored the effects of vitamin B6 in conjunction with D-penicillamine (DPA) as a treatment for methyl mercury poisoning in a study involving female rats. The research aimed to understand how this vitamin might support recovery during food poisoning caused by mercury exposure.
The study observed changes in food consumption and body weight as early indicators of methyl mercury toxicity, noting a significant 75% decrease in food intake within the first day. Interestingly, while DPA effectively prevented neurological symptoms and enhanced recovery, vitamin B6's specific impact on food poisoning was less clear. It appeared that DPA's positive effects could be counterbalanced by vitamin B6, as it sometimes reduced food consumption and body weight.
Overall, while DPA showed promise in mitigating the effects of methyl mercury, the role of vitamin B6 was not distinct enough to draw firm conclusions regarding its effectiveness. Therefore, we found that vitamin B6 did not significantly enhance treatment outcomes, emphasizing the complexity of using multiple interventions in managing food poisoning.
The study observed changes in food consumption and body weight as early indicators of methyl mercury toxicity, noting a significant 75% decrease in food intake within the first day. Interestingly, while DPA effectively prevented neurological symptoms and enhanced recovery, vitamin B6's specific impact on food poisoning was less clear. It appeared that DPA's positive effects could be counterbalanced by vitamin B6, as it sometimes reduced food consumption and body weight.
Overall, while DPA showed promise in mitigating the effects of methyl mercury, the role of vitamin B6 was not distinct enough to draw firm conclusions regarding its effectiveness. Therefore, we found that vitamin B6 did not significantly enhance treatment outcomes, emphasizing the complexity of using multiple interventions in managing food poisoning.
References
- Hirakawa H, Suzue K, Uchida M, Takita A, Kamitani W, et al. A Macroporous Magnesium Oxide-Templated Carbon Adsorbs Shiga Toxins and Type III Secretory Proteins in Enterohemorrhagic , Which Attenuates Virulence. Front Microbiol. 2022;13:883689. 10.3389/fmicb.2022.883689
- Kajiyama Y, Fujii K, Takeuchi H, Manabe Y. Ginkgo seed poisoning. Pediatrics. 2002;109:325.
- Folkers K, Shizukuishi S, Willis R, Scudder SL, Takemura K, et al. The biochemistry of vitamin B6 is basic to the cause of the Chinese restaurant syndrome. Hoppe Seylers Z Physiol Chem. 1984;365:405.
- Lapin CA, Carter DE. Early indices of methyl mercury toxicity and their use in treatment evaluation. J Toxicol Environ Health. 1981;8:767.
