Reviewed By
Overview
SCIENTIFIC SCORE
Possibly Effective
Based on 2 Researches
7
USERS' SCORE
Good
Based on 2 Reviews
8.4
Supplement Facts
Serving Size: 3 Tablets
Amount Per Serving
%DV
Vitamin B6 (as pyridoxine HCl)
25 mg
1,471%
Magnesium (as magnesium oxide)
400 mg
95%
Top Medical Research Studies
7
We explored the impact of chronic stress on gastritis and how vitamin B6 might play a role in treatment. In our investigation, we employed the water avoidance stress test in mouse models to simulate the impacts of stress on the stomach. This method allowed us to closely examine how stress alters gastric conditions and the microbiota.
Our findings indicated that water avoidance stress led to decreased levels of hydrogen sulfide (H2S) in the stomach, which correlated with increased inflammation and disruption of the stomach's microbiota. When we supplemented with sodium hydrosulfide and vitamin B6, we observed partial reversal of inflammation and microbial imbalance.
Although vitamin B6 alone was tested alongside sodium hydrosulfide, it shows promise as a potential treatment option for stress-induced gastritis. This is especially relevant given the rising incidence of chronic gastritis linked to high-stress lifestyles. Our research offers insights that could pave the way for new strategies to prevent and treat gastritis related to stress.
Our findings indicated that water avoidance stress led to decreased levels of hydrogen sulfide (H2S) in the stomach, which correlated with increased inflammation and disruption of the stomach's microbiota. When we supplemented with sodium hydrosulfide and vitamin B6, we observed partial reversal of inflammation and microbial imbalance.
Although vitamin B6 alone was tested alongside sodium hydrosulfide, it shows promise as a potential treatment option for stress-induced gastritis. This is especially relevant given the rising incidence of chronic gastritis linked to high-stress lifestyles. Our research offers insights that could pave the way for new strategies to prevent and treat gastritis related to stress.
Read More
7
Vitamin B6's unclear effectiveness
In our quest to understand the impact of vitamin B6 treatment in elderly individuals with gastritis, we conducted a study involving 209 community-dwelling participants, each receiving a daily oral regimen of B-vitamins or a placebo over four months. The participants were carefully evaluated before and after the treatment to measure various health markers, including levels of vitamin B12, folic acid, and iron.
Throughout the study, we found that a significant number of subjects had chronic atrophic gastritis (AG) and antibodies against Helicobacter pylori. While AG was associated with lower vitamin B12 levels and higher homocysteine and methylmalonic acid levels—a sign of vitamin B12 deficiency—we observed that those with AG responded positively to vitamin B treatment. Though the changes in biochemical markers for those with AG were greater, the results did not reach statistical significance.
It’s important to note that while vitamin B6 was part of the treatment regimen, we couldn’t isolate its specific effects due to the combination with other B vitamins. Therefore, we remain cautious about making definitive assertions on the efficacy of vitamin B6 alone in managing atrophic gastritis. Our findings suggest that while vitamin B treatment is beneficial, especially for individuals with AG, the role of vitamin B6 requires further investigation for clarity and specificity.
Throughout the study, we found that a significant number of subjects had chronic atrophic gastritis (AG) and antibodies against Helicobacter pylori. While AG was associated with lower vitamin B12 levels and higher homocysteine and methylmalonic acid levels—a sign of vitamin B12 deficiency—we observed that those with AG responded positively to vitamin B treatment. Though the changes in biochemical markers for those with AG were greater, the results did not reach statistical significance.
It’s important to note that while vitamin B6 was part of the treatment regimen, we couldn’t isolate its specific effects due to the combination with other B vitamins. Therefore, we remain cautious about making definitive assertions on the efficacy of vitamin B6 alone in managing atrophic gastritis. Our findings suggest that while vitamin B treatment is beneficial, especially for individuals with AG, the role of vitamin B6 requires further investigation for clarity and specificity.
Read More
Most Useful Reviews
9
Effective for gastritis
I have found this company and its product to be excellent. Some people are hesitant about the magnesium oxide content, but for gastritis or an ulcer, it's precisely what’s needed. A quick search online will yield ample information. I highly recommend it!
Read More
7.5
Supports gastritis relief
6 people found this helpful
Magnesium Oxide has proven to be a helpful ally in managing gastritis. This antacid agent effectively lowers gastric acidity, as it does not absorb into the stomach but rather neutralises hydrochloric acid. It doesn't lead to carbon dioxide release, so its antacid effects don't result in secondary hypersecretion or alkalosis. In the intestines, it takes on a laxative role, alleviating heartburn and discomfort from acid stagnation. However, individuals with normal or low acidity should weigh the pros and cons and consult a doctor before use. Thank you for your consideration.
Read More
Medical Researches
SCIENTIFIC SCORE
Possibly Effective
Based on 2 Researches
7
- All Researches
7
We explored the impact of chronic stress on gastritis and how vitamin B6 might play a role in treatment. In our investigation, we employed the water avoidance stress test in mouse models to simulate the impacts of stress on the stomach. This method allowed us to closely examine how stress alters gastric conditions and the microbiota.
Our findings indicated that water avoidance stress led to decreased levels of hydrogen sulfide (H2S) in the stomach, which correlated with increased inflammation and disruption of the stomach's microbiota. When we supplemented with sodium hydrosulfide and vitamin B6, we observed partial reversal of inflammation and microbial imbalance.
Although vitamin B6 alone was tested alongside sodium hydrosulfide, it shows promise as a potential treatment option for stress-induced gastritis. This is especially relevant given the rising incidence of chronic gastritis linked to high-stress lifestyles. Our research offers insights that could pave the way for new strategies to prevent and treat gastritis related to stress.
Our findings indicated that water avoidance stress led to decreased levels of hydrogen sulfide (H2S) in the stomach, which correlated with increased inflammation and disruption of the stomach's microbiota. When we supplemented with sodium hydrosulfide and vitamin B6, we observed partial reversal of inflammation and microbial imbalance.
Although vitamin B6 alone was tested alongside sodium hydrosulfide, it shows promise as a potential treatment option for stress-induced gastritis. This is especially relevant given the rising incidence of chronic gastritis linked to high-stress lifestyles. Our research offers insights that could pave the way for new strategies to prevent and treat gastritis related to stress.
Read More
7
Vitamin B6's unclear effectiveness
In our quest to understand the impact of vitamin B6 treatment in elderly individuals with gastritis, we conducted a study involving 209 community-dwelling participants, each receiving a daily oral regimen of B-vitamins or a placebo over four months. The participants were carefully evaluated before and after the treatment to measure various health markers, including levels of vitamin B12, folic acid, and iron.
Throughout the study, we found that a significant number of subjects had chronic atrophic gastritis (AG) and antibodies against Helicobacter pylori. While AG was associated with lower vitamin B12 levels and higher homocysteine and methylmalonic acid levels—a sign of vitamin B12 deficiency—we observed that those with AG responded positively to vitamin B treatment. Though the changes in biochemical markers for those with AG were greater, the results did not reach statistical significance.
It’s important to note that while vitamin B6 was part of the treatment regimen, we couldn’t isolate its specific effects due to the combination with other B vitamins. Therefore, we remain cautious about making definitive assertions on the efficacy of vitamin B6 alone in managing atrophic gastritis. Our findings suggest that while vitamin B treatment is beneficial, especially for individuals with AG, the role of vitamin B6 requires further investigation for clarity and specificity.
Throughout the study, we found that a significant number of subjects had chronic atrophic gastritis (AG) and antibodies against Helicobacter pylori. While AG was associated with lower vitamin B12 levels and higher homocysteine and methylmalonic acid levels—a sign of vitamin B12 deficiency—we observed that those with AG responded positively to vitamin B treatment. Though the changes in biochemical markers for those with AG were greater, the results did not reach statistical significance.
It’s important to note that while vitamin B6 was part of the treatment regimen, we couldn’t isolate its specific effects due to the combination with other B vitamins. Therefore, we remain cautious about making definitive assertions on the efficacy of vitamin B6 alone in managing atrophic gastritis. Our findings suggest that while vitamin B treatment is beneficial, especially for individuals with AG, the role of vitamin B6 requires further investigation for clarity and specificity.
Read More
User Reviews
USERS' SCORE
Good
Based on 2 Reviews
8.4
- All Reviews
- Positive Reviews
- Negative Reviews
9
Effective for gastritis
I have found this company and its product to be excellent. Some people are hesitant about the magnesium oxide content, but for gastritis or an ulcer, it's precisely what’s needed. A quick search online will yield ample information. I highly recommend it!
Read More
7.5
Supports gastritis relief
6 people found this helpful
Magnesium Oxide has proven to be a helpful ally in managing gastritis. This antacid agent effectively lowers gastric acidity, as it does not absorb into the stomach but rather neutralises hydrochloric acid. It doesn't lead to carbon dioxide release, so its antacid effects don't result in secondary hypersecretion or alkalosis. In the intestines, it takes on a laxative role, alleviating heartburn and discomfort from acid stagnation. However, individuals with normal or low acidity should weigh the pros and cons and consult a doctor before use. Thank you for your consideration.
Read More
Frequently Asked Questions
No FAQs are available for this product and symptom.
References
- Han Y, Li Y, Hu Z, Wang X, Liu J, et al. Hydrogen sulfide-mediated resistance against water avoidance stress-induced gastritis by maintenance of gastric microbial homeostasis. Microbiologyopen. 2020;9:e00951. 10.1002/mbo3.951
- Lewerin C, Jacobsson S, Lindstedt G, Nilsson-Ehle H. Serum biomarkers for atrophic gastritis and antibodies against Helicobacter pylori in the elderly: Implications for vitamin B12, folic acid and iron status and response to oral vitamin therapy. Scand J Gastroenterol. 2008;43:1050. 10.1080/00365520802078341
