Reviewed By
Overview
SCIENTIFIC SCORE
Possibly Effective
Based on 32 Researches
7.8
USERS' SCORE
Moderately Good
Based on 20 Reviews
7.7
Supplement Facts
Serving Size: 3 Tablets
Amount Per Serving
%DV
Vitamin B6 (as pyridoxine HCl)
25 mg
1,471%
Magnesium (as magnesium oxide)
400 mg
95%
Top Medical Research Studies
7
We examined how magnesium supplements might influence heart failure and serious heart-related issues in diabetic patients.
In a study involving over 94,000 veterans, we found that those taking magnesium supplements experienced a lower risk of heart failure compared to nonusers. Specifically, 8.0% of supplement users developed heart failure, versus 9.7% of nonusers.
Furthermore, magnesium intake was linked to a reduced chance of major adverse cardiac events. However, it’s important to note that these findings need further investigation through randomized controlled trials.
In a study involving over 94,000 veterans, we found that those taking magnesium supplements experienced a lower risk of heart failure compared to nonusers. Specifically, 8.0% of supplement users developed heart failure, versus 9.7% of nonusers.
Furthermore, magnesium intake was linked to a reduced chance of major adverse cardiac events. However, it’s important to note that these findings need further investigation through randomized controlled trials.
Read More
9
We explored how magnesium supplementation might influence mortality rates in patients with heart failure and preserved ejection fraction (HFpEF). The study involved nearly 2,000 patients, with careful matching to ensure a fair comparison between those receiving magnesium and those who weren’t.
Interestingly, we found that magnesium intake was linked to a significant reduction in 28-day mortality rates. This effect was most notable in older adults, women, and patients with high blood pressure. Despite these positive findings, magnesium treatment did lead to longer hospital and ICU stays.
Overall, magnesium shows promise as a supportive treatment for HFpEF, but further investigation is necessary to better understand its benefits and implications.
Interestingly, we found that magnesium intake was linked to a significant reduction in 28-day mortality rates. This effect was most notable in older adults, women, and patients with high blood pressure. Despite these positive findings, magnesium treatment did lead to longer hospital and ICU stays.
Overall, magnesium shows promise as a supportive treatment for HFpEF, but further investigation is necessary to better understand its benefits and implications.
Read More
8
Magnesium levels and heart disease mortality
We examined the link between serum magnesium levels and the risk of death from heart failure, coronary heart disease, and stroke in patients with chronic kidney disease who don’t require dialysis. Over a decade, we followed 1,271 patients, noting that those with higher magnesium levels experienced significantly lower mortality rates from these conditions.
This suggests that maintaining adequate magnesium levels may help improve health outcomes for individuals with advanced kidney issues and an increased risk of cardiovascular problems.
This suggests that maintaining adequate magnesium levels may help improve health outcomes for individuals with advanced kidney issues and an increased risk of cardiovascular problems.
Read More
Most Useful Reviews
8
Overall health supported
2 people found this helpful
These Solgar supplements deliver a great combination of magnesium and vitamin B6. They aid heart health, regulate calcium absorption, and support overall bodily functions. I've found this synergy to be greatly beneficial to my wellbeing.
Read More
9
Normalised heart rhythm
1 people found this helpful
This magnesium is the best! After trying it, the difference is palpable! It truly normalises sleep, alleviates anxiety, and regulates heart rhythm. The quality of Solgar is evident from the outset, with even the dark glass packaging reflecting the brand's dedication to consumer quality.
Read More
7.5
Regulated heartbeat
1 people found this helpful
I have used this product for over ten years. I suffered from irregular heartbeats, which adjusted within a few weeks. I continue to use it.
Read More
Medical Researches
SCIENTIFIC SCORE
Possibly Effective
Based on 32 Researches
7.8
- All Researches
9
We explored how magnesium supplementation might influence mortality rates in patients with heart failure and preserved ejection fraction (HFpEF). The study involved nearly 2,000 patients, with careful matching to ensure a fair comparison between those receiving magnesium and those who weren’t.
Interestingly, we found that magnesium intake was linked to a significant reduction in 28-day mortality rates. This effect was most notable in older adults, women, and patients with high blood pressure. Despite these positive findings, magnesium treatment did lead to longer hospital and ICU stays.
Overall, magnesium shows promise as a supportive treatment for HFpEF, but further investigation is necessary to better understand its benefits and implications.
Interestingly, we found that magnesium intake was linked to a significant reduction in 28-day mortality rates. This effect was most notable in older adults, women, and patients with high blood pressure. Despite these positive findings, magnesium treatment did lead to longer hospital and ICU stays.
Overall, magnesium shows promise as a supportive treatment for HFpEF, but further investigation is necessary to better understand its benefits and implications.
Read More
9
We explored the effects of vitamin B6 (pyridoxine) on heart health, specifically looking at its protective qualities against angina provoked by vasopressin in a rat model. Vasopressin was administered to observe its impact on heart function, which included elevated stress on the heart indicated by changes on the electrocardiogram and increased cardiac enzymes.
The study found that when we gave rats pyridoxine in varying doses, it effectively reduced the ST elevation and heart rate changes caused by vasopressin. Notably, higher doses of pyridoxine (7 mg/kg) showed significant protective effects, outperforming both amlodipine and isosorbide. In addition, we observed that pyridoxine at these doses helped prevent cardiac tissue damage and improved heart structure.
Interestingly, while combining pyridoxine with amlodipine led to a trend of increased adverse cardiovascular events, the results underscored the potential of vitamin B6 in enhancing heart health. It appears vitamin B6 may work by improving certain functions in the body that support heart health, such as better blood vessel function and reduced levels of harmful substances.
Overall, our findings suggest that vitamin B6 could serve as a promising agent in preventing coronary heart disease, but more research is necessary to fully explore its benefits and practical applications in humans.
The study found that when we gave rats pyridoxine in varying doses, it effectively reduced the ST elevation and heart rate changes caused by vasopressin. Notably, higher doses of pyridoxine (7 mg/kg) showed significant protective effects, outperforming both amlodipine and isosorbide. In addition, we observed that pyridoxine at these doses helped prevent cardiac tissue damage and improved heart structure.
Interestingly, while combining pyridoxine with amlodipine led to a trend of increased adverse cardiovascular events, the results underscored the potential of vitamin B6 in enhancing heart health. It appears vitamin B6 may work by improving certain functions in the body that support heart health, such as better blood vessel function and reduced levels of harmful substances.
Overall, our findings suggest that vitamin B6 could serve as a promising agent in preventing coronary heart disease, but more research is necessary to fully explore its benefits and practical applications in humans.
Read More
9
We explored the effects of vitamin B6 (VB6) on heart recovery after an acute myocardial infarction (AMI). The study aimed to determine if VB6 could promote angiogenesis, the process of new blood vessel formation, which is crucial for healing the heart after such an event.
To investigate this, we looked at the ability of VB6 to enhance cell migration and tube formation in human umbilical vein endothelial cells, which are key players in the formation of blood vessels. Our results showed that VB6 not only encouraged these processes but also increased the phosphorylation of AMPK, a protein that plays a vital role in cellular energy regulation.
Importantly, these beneficial effects of VB6 on cell behavior were found to depend on AMPK activation. When we used specific inhibitors to block AMPK, the positive changes from VB6 were no longer observed. Additionally, in an animal model, long-term supplementing with VB6 led to significant improvements in heart function, more new blood vessel growth, and reduced inflammation markers in mice after AMI.
In summary, our findings suggest that vitamin B6 could be an effective support for heart recovery due to its role in promoting angiogenesis through AMPK activation following heart attacks. Given that VB6 shows promise in limiting ischemic heart injury, it could be a valuable addition to existing heart disease treatments.
To investigate this, we looked at the ability of VB6 to enhance cell migration and tube formation in human umbilical vein endothelial cells, which are key players in the formation of blood vessels. Our results showed that VB6 not only encouraged these processes but also increased the phosphorylation of AMPK, a protein that plays a vital role in cellular energy regulation.
Importantly, these beneficial effects of VB6 on cell behavior were found to depend on AMPK activation. When we used specific inhibitors to block AMPK, the positive changes from VB6 were no longer observed. Additionally, in an animal model, long-term supplementing with VB6 led to significant improvements in heart function, more new blood vessel growth, and reduced inflammation markers in mice after AMI.
In summary, our findings suggest that vitamin B6 could be an effective support for heart recovery due to its role in promoting angiogenesis through AMPK activation following heart attacks. Given that VB6 shows promise in limiting ischemic heart injury, it could be a valuable addition to existing heart disease treatments.
Read More
9
We examined how vitamin B-6 might play a role in preventing heart failure with preserved ejection fraction (HFpEF), a condition that often results from changes in heart-related immune cells called macrophages. Our research was based on a mouse model that mimicked HFpEF through a high-fat diet paired with a specific supplement. By monitoring heart function using various imaging techniques, as well as examining heart tissue for changes, we gathered important insights into vitamin B-6's potential benefits.
We found that when vitamin B-6 was added to the diet of mice prone to HFpEF, it significantly improved several heart failure symptoms. There were notable enhancements in heart function, reducing pressure in the heart and allowing for better exercise capacity. However, we made a crucial discovery: the positive effects of vitamin B-6 were diminished when we examined mice lacking a specific protein called DOK3. This suggests that DOK3 is key to vitamin B-6’s success in mitigating heart failure symptoms.
Essentially, our findings indicate that vitamin B-6 might lower the risk of heart failure by halting harmful changes in cardiac macrophages thanks to its ability to boost DOK3 signaling. This research offers exciting possibilities for a new therapeutic approach aimed at improving heart health and managing HFpEF effectively.
We found that when vitamin B-6 was added to the diet of mice prone to HFpEF, it significantly improved several heart failure symptoms. There were notable enhancements in heart function, reducing pressure in the heart and allowing for better exercise capacity. However, we made a crucial discovery: the positive effects of vitamin B-6 were diminished when we examined mice lacking a specific protein called DOK3. This suggests that DOK3 is key to vitamin B-6’s success in mitigating heart failure symptoms.
Essentially, our findings indicate that vitamin B-6 might lower the risk of heart failure by halting harmful changes in cardiac macrophages thanks to its ability to boost DOK3 signaling. This research offers exciting possibilities for a new therapeutic approach aimed at improving heart health and managing HFpEF effectively.
Read More
9
We focused on how pyridoxamine, a form of vitamin B6, impacts heart health during treatment with doxorubicin, a common cancer drug. In an experimental setup with Sprague Dawley rats, we observed that those receiving doxorubicin experienced a decrease in heart function, specifically a reduced left ventricular ejection fraction, and an increase in heart volume.
Notably, when we added pyridoxamine to the treatment, these harmful effects were significantly lessened. The rats that took pyridoxamine alongside doxorubicin maintained better heart function compared to those who only received doxorubicin. This suggests that pyridoxamine acts as a protective agent for the heart, countering some of the negative impacts caused by doxorubicin.
However, we also investigated how doxorubicin and pyridoxamine affected breast cancer cells in the lab. While doxorubicin effectively reduced cancer cell viability and increased cell death, pyridoxamine didn’t change these outcomes. This indicates that while pyridoxamine can preserve heart health during chemotherapy, it doesn’t interfere with the cancer-fighting effects of doxorubicin.
Overall, this research highlights pyridoxamine's promising role as a cardioprotectant during cancer treatment, allowing for heart preservation without diminishing the effectiveness of anticancer therapies.
Notably, when we added pyridoxamine to the treatment, these harmful effects were significantly lessened. The rats that took pyridoxamine alongside doxorubicin maintained better heart function compared to those who only received doxorubicin. This suggests that pyridoxamine acts as a protective agent for the heart, countering some of the negative impacts caused by doxorubicin.
However, we also investigated how doxorubicin and pyridoxamine affected breast cancer cells in the lab. While doxorubicin effectively reduced cancer cell viability and increased cell death, pyridoxamine didn’t change these outcomes. This indicates that while pyridoxamine can preserve heart health during chemotherapy, it doesn’t interfere with the cancer-fighting effects of doxorubicin.
Overall, this research highlights pyridoxamine's promising role as a cardioprotectant during cancer treatment, allowing for heart preservation without diminishing the effectiveness of anticancer therapies.
Read More
User Reviews
USERS' SCORE
Moderately Good
Based on 20 Reviews
7.7
- All Reviews
- Positive Reviews
- Negative Reviews
8
Overall health supported
2 people found this helpful
These Solgar supplements deliver a great combination of magnesium and vitamin B6. They aid heart health, regulate calcium absorption, and support overall bodily functions. I've found this synergy to be greatly beneficial to my wellbeing.
Read More
9
Normalised heart rhythm
1 people found this helpful
This magnesium is the best! After trying it, the difference is palpable! It truly normalises sleep, alleviates anxiety, and regulates heart rhythm. The quality of Solgar is evident from the outset, with even the dark glass packaging reflecting the brand's dedication to consumer quality.
Read More
7.5
Regulated heartbeat
1 people found this helpful
I have used this product for over ten years. I suffered from irregular heartbeats, which adjusted within a few weeks. I continue to use it.
Read More
9
Anxiety alleviated
36 people found this helpful
Since I started taking magnesium B6, my life has improved dramatically. I no longer experience dizziness, heart palpitations, or insomnia. It has almost eliminated my anxiety and irritability. Sleeping much better, I feel rejuvenated. This supplement truly transformed my wellbeing.
Read More
7.5
Heart discomfort lessened
4 people found this helpful
Choosing Super Magnesium was a wise decision. After consistently taking it for a month, my energy levels increased and heart discomfort decreased. Being aware of magnesium's essential role, I am pleased with its effects on my sleep and overall wellness. This brand truly delivers.
Read More
Frequently Asked Questions
7.5
Regulated heartbeat
1 people found this helpful
I have used this product for over ten years. I suffered from irregular heartbeats, which adjusted within a few weeks. I continue to use it.
7.5
Heart discomfort lessened
4 people found this helpful
Choosing Super Magnesium was a wise decision. After consistently taking it for a month, my energy levels increased and heart discomfort decreased. Being aware of magnesium's essential role, I am pleased with its effects on my sleep and overall wellness. This brand truly delivers.
6
Nerves calmed
83 people found this helpful
I was unaware of my magnesium deficiency until my therapist indicated a poor cardiogram. The cost initially shocked me, but upon using Magne B6, I realised it offers cumulative benefits over time. Now, my heart no longer races and my anxiety has eased.
7.5
Sleep improved
3 people found this helpful
So far, the magnesium has helped me sleep better and calmed my nerves significantly. I take it before bed and have experienced restful nights without interruption. I highly recommend it for anyone experiencing insomnia or anxiety.
9
Anxiety alleviated
36 people found this helpful
Since I started taking magnesium B6, my life has improved dramatically. I no longer experience dizziness, heart palpitations, or insomnia. It has almost eliminated my anxiety and irritability. Sleeping much better, I feel rejuvenated. This supplement truly transformed my wellbeing.
9
Heart rate control
2 people found this helpful
She discovered that magnesium glycinate is the most effective for calming the nervous system and enhancing focus. To regulate the rapid pulse associated with systemic nervous disorders, this magnesium is simply outstanding. I take it in the morning, and throughout the day, my heart rate remains stable.
8
Overall health supported
2 people found this helpful
These Solgar supplements deliver a great combination of magnesium and vitamin B6. They aid heart health, regulate calcium absorption, and support overall bodily functions. I've found this synergy to be greatly beneficial to my wellbeing.
7.5
Supports heart health
Magnesium plays a vital role in bolstering bones, promoting heart health and alleviating stress; however, it is advisable to avoid magnesium oxide as a supplement.
7
We examined how magnesium supplements might influence heart failure and serious heart-related issues in diabetic patients.
In a study involving over 94,000 veterans, we found that those taking magnesium supplements experienced a lower risk of heart failure compared to nonusers. Specifically, 8.0% of supplement users developed heart failure, versus 9.7% of nonusers.
Furthermore, magnesium intake was linked to a reduced chance of major adverse cardiac events. However, it’s important to note that these findings need further investigation through randomized controlled trials.
In a study involving over 94,000 veterans, we found that those taking magnesium supplements experienced a lower risk of heart failure compared to nonusers. Specifically, 8.0% of supplement users developed heart failure, versus 9.7% of nonusers.
Furthermore, magnesium intake was linked to a reduced chance of major adverse cardiac events. However, it’s important to note that these findings need further investigation through randomized controlled trials.
8
Magnesium levels and heart disease mortality
We examined the link between serum magnesium levels and the risk of death from heart failure, coronary heart disease, and stroke in patients with chronic kidney disease who don’t require dialysis. Over a decade, we followed 1,271 patients, noting that those with higher magnesium levels experienced significantly lower mortality rates from these conditions.
This suggests that maintaining adequate magnesium levels may help improve health outcomes for individuals with advanced kidney issues and an increased risk of cardiovascular problems.
This suggests that maintaining adequate magnesium levels may help improve health outcomes for individuals with advanced kidney issues and an increased risk of cardiovascular problems.
7
We investigated the effect of magnesium and calcium on blood sugar levels in 11,934 patients with coronary artery disease. Our findings indicated that higher serum magnesium levels and a favorable magnesium to calcium ratio were associated with lower abnormal HbA1c levels, which reflect better blood sugar management. In contrast, calcium showed no significant association with HbA1c levels. Importantly, we found no evidence that inflammation played a role in this relationship. Overall, magnesium might be beneficial for maintaining healthy blood sugar levels in those with heart disease.
8
Magnesium intake impacts heart disease risk
We explored the link between magnesium intake and heart disease risk in young adults, using a comprehensive study of U.S. adults aged 20 to 34. This cross-sectional research analyzed data from the National Health and Nutrition Examination Survey, examining dietary habits and various cardiovascular factors.
Our findings suggest that higher magnesium intake is associated with a lower risk of future cardiovascular issues and non-HDL cholesterol problems. This suggests that including magnesium-rich foods in our diets could promote heart health early in life.
Our findings suggest that higher magnesium intake is associated with a lower risk of future cardiovascular issues and non-HDL cholesterol problems. This suggests that including magnesium-rich foods in our diets could promote heart health early in life.
References
- Cheng Y, Zullo AR, Yin Y, Shao Y, Liu S, et al. Nonprescription Magnesium Supplement Use and Risk of Heart Failure in Patients With Diabetes: A Target Trial Emulation. J Am Heart Assoc. 2025;14:e038870. 10.1161/JAHA.124.038870
- Moyano-Peregrin C, Rodelo-Haad C, Martín-Malo A, Muñoz-Castañeda JR, Ojeda R, et al. Upper normal serum magnesium is associated with a reduction in incident death from fatal heart failure, coronary heart disease and stroke in non-dialysis patients with CKD stages 4 and 5. Clin Kidney J. 2025;18:sfae390. 10.1093/ckj/sfae390
- Dong H, Lu N, Wang J, Hu P. Serum magnesium, not calcium, is inversely associated with abnormal HbA1c concentrations in adults with coronary artery disease. Asia Pac J Clin Nutr. 2025;34:104. 10.6133/apjcn.202502_34(1).0010
- Song L, Ying J, Li M, Ying L, Zhao C. Propensity score matched cohort study on magnesium supplementation and mortality in critically ill patients with HFpEF. Sci Rep. 2025;15:1944. 10.1038/s41598-025-85931-1
- Sun L, Du J. Magnesium status, serum vitamin D concentration and mortality among congestive heart failure patients: a cohort study from NHANES 2007-2018. Magnes Res. 2024;37:61. 10.1684/mrh.2024.0528
- Song Q, Song L, Liu H, Tan H, Yang B, et al. Association of magnesium intake with predicted atherosclerotic lesions and cardiovascular risk in young adults based on PDAY score: a cross-sectional study. BMC Public Health. 2024;24:3232. 10.1186/s12889-024-20785-2
- Behers BJ, Behers BM, Stephenson-Moe CA, Vargas IA, Meng Z, et al. Magnesium and Potassium Supplementation for Systolic Blood Pressure Reduction in the General Normotensive Population: A Systematic Review and Subgroup Meta-Analysis for Optimal Dosage and Treatment Length. Nutrients. 2024;16. 10.3390/nu16213617
- Jiang Y, Luo B, Chen Y, Lu W, Peng Y, et al. Serum calcium-magnesium ratio at admission predicts adverse outcomes in patients with acute coronary syndrome. PLoS One. 2024;19:e0313352. 10.1371/journal.pone.0313352
- Wyss C, Gündling PW, Kostev K. Real world effectiveness of Hawthorn special extract WS 1442 in a retrospective cohort study from Germany. Sci Rep. 2024;14:22986. 10.1038/s41598-024-74325-4
- Seguchi M, Aytekin A, Xhepa E, Haude M, Wlodarczak A, et al. Vascular response following implantation of the third-generation drug-eluting resorbable coronary magnesium scaffold: an intravascular imaging analysis of the BIOMAG-I first-in-human study. EuroIntervention. 2024;20:e1173. 10.4244/EIJ-D-24-00055
- Zhang J, Chen Z, Rao L, He Y. Coronary bioresorbable metallic stents: Advancements and future perspectives. J Cardiol. 2025;85:69. 10.1016/j.jjcc.2024.08.003
- Copp KL, Steffen LM, Yi SY, Lutsey PL, Rebholz CM, et al. Magnesium-rich diet score is inversely associated with incident cardiovascular disease: the Atherosclerosis Risk in Communities (ARIC) study. Eur J Prev Cardiol. 2025;32:386. 10.1093/eurjpc/zwae251
- Zhuang J, Zhang Q, Wang H, Su PH, Chen PY. Association between short-term changes in serum magnesium and in-hospital mortality following acute myocardial infarction: a cohort study based on the MIMIC database. Magnes Res. 2024;37:45. 10.1684/mrh.2024.0517
- Fruh V, Babalola T, Sears C, Wellenius GA, Webster TF, et al. Dietary Minerals and Incident Cardiovascular Outcomes among Never-Smokers in a Danish Case-Cohort Study. Int J Environ Res Public Health. 2024;21. 10.3390/ijerph21070932
- Tao J, Wang J, Peng H, Yuan Y, Lai H, et al. Association between serum phosphate, magnesium, calcium and aortic valve sclerosis: a propensity score-matched case-control study. Acta Cardiol. 2024;79:522. 10.1080/00015385.2024.2379682
- Zhang J, Sun D, Guo Y, Tong J, Liu Q, et al. Targeted delivery of black phosphorus nanosheets by ROS responsive complex hydrogel based on angiogenesis and antioxidant promotes myocardial infarction repair. J Nanobiotechnology. 2024;22:433. 10.1186/s12951-024-02685-0
- Al-Khawlani MA, Al-Madhagi WM, Sabati AM, ALomaisi SAMA, Al-Najar M. Protective effects of pyridoxine, amlodipine, and their combination in a vasopressin-induced angina model in rats. Naunyn Schmiedebergs Arch Pharmacol. 2025. 10.1007/s00210-025-03905-6
- Wang XQ, Yin S, Wang QW, Bai WW, Tan RH, et al. Vitamin B6 allosterically activates AMPK to promote postischemic angiogenesis in mice. Eur J Pharmacol. 2025;993:177413. 10.1016/j.ejphar.2025.177413
- Li B, Hu M, Ma Y, Sun X, Wu D, et al. Association between Vitamin E, Vitamin B6, and Vitamin B12 with coronary heart disease. Sci Rep. 2024;14:19960. 10.1038/s41598-024-68413-8
- Song JW, Zhang ZS, Chen L, Wang QW, Xu JY, et al. Vitamin B-6 Prevents Heart Failure with Preserved Ejection Fraction Through Downstream of Kinase 3 in a Mouse Model. J Nutr. 2024;154:3031. 10.1016/j.tjnut.2024.08.006
- Agraib LM, Al-Shami I, Alkhatib B, Hasan H. The impact of energy releasing B-vitamin intake on indices of obesity and cardiac function: a cross-sectional study. F1000Res. 2023;12:1382.
- D'Haese S, Claes L, Jaeken E, Deluyker D, Evens L, et al. Pyridoxamine Alleviates Cardiac Fibrosis and Oxidative Stress in Western Diet-Induced Prediabetic Rats. Int J Mol Sci. 2024;25. 10.3390/ijms25158508
- Haesen S, Verghote E, Heeren E, Wolfs E, Deluyker D, et al. Pyridoxamine Attenuates Doxorubicin-Induced Cardiomyopathy without Affecting Its Antitumor Effect on Rat Mammary Tumor Cells. Cells. 2024;13. 10.3390/cells13020120
- Faingold II, Smolina AV, Soldatova YV, Poletaeva DA, Balakina AA, et al. Cardioprotective Effect of 2-Ethyl-3-Hydroxy-6-Methylpyridinium 2-Nitroxysuccinate Against Adrenaline/Hydrocortisone-Induced Myocardial Ischemia in Mice: Modulation of Free-Radical Processes in Biomembranes and Monoamine Oxidase A Activity. Cell Biochem Biophys. 2024;82:235. 10.1007/s12013-023-01203-7
- Sun RL, Wang HH, Gui ZC, Lin LB, Fan JX, et al. Protective effect of vitamin B against doxorubicin-induced cardiotoxicity by modulating NHE1 expression. J Biochem Mol Toxicol. 2023;37:e23403. 10.1002/jbt.23403
- Hanssen NMJ, Tikellis C, Pickering RJ, Dragoljevic D, Lee MKS, et al. Pyridoxamine prevents increased atherosclerosis by intermittent methylglyoxal spikes in the aortic arches of ApoE mice. Biomed Pharmacother. 2023;158:114211. 10.1016/j.biopha.2022.114211
- Bajic Z, Sobot T, Skrbic R, Stojiljkovic MP, Ponorac N, et al. Homocysteine, Vitamins B6 and Folic Acid in Experimental Models of Myocardial Infarction and Heart Failure-How Strong Is That Link?. Biomolecules. 2022;12. 10.3390/biom12040536
- Hu L, Li Y, Liu Z, Fan F, Xu B, et al. Association of Plasma Vitamin B6 With Coronary Heart Disease in Patients Undergoing Diagnostic Coronary Angiography: New Insight on Sex Differences. Front Cardiovasc Med. 2021;8:789669. 10.3389/fcvm.2021.789669
- Huang TH, Chang HH, Guo YR, Chang WC, Chen YF. Vitamin B Mitigates Thoracic Aortic Dilation in Marfan Syndrome Mice by Restoring the Canonical TGF-β Pathway. Int J Mol Sci. 2021;22. 10.3390/ijms222111737
- Shah AK, Dhalla NS. Effectiveness of Some Vitamins in the Prevention of Cardiovascular Disease: A Narrative Review. Front Physiol. 2021;12:729255. 10.3389/fphys.2021.729255
- Evens L, Beliën H, D'Haese S, Haesen S, Verboven M, et al. Combinational Therapy of Cardiac Atrial Appendage Stem Cells and Pyridoxamine: The Road to Cardiac Repair?. Int J Mol Sci. 2021;22. 10.3390/ijms22179266
- Kumrungsee T, Yanaka N, Suda T, Kato N. Emerging cardioprotective mechanisms of vitamin B6: a narrative review. Eur J Nutr. 2022;61:605. 10.1007/s00394-021-02665-2
