Reviewed By
Overview
SCIENTIFIC SCORE
Possibly Effective
Based on 6 Researches
7.2
USERS' SCORE
Good
Based on 5 Reviews
8
Supplement Facts
Serving Size: 3 Tablets
Amount Per Serving
%DV
Vitamin B6 (as pyridoxine HCl)
25 mg
1,471%
Magnesium (as magnesium oxide)
400 mg
95%
Top Medical Research Studies
8
We conducted a study to discover how magnesium sulfate affects nausea during orthognathic surgery. In this research, we divided 75 adult patients into two groups: one group received magnesium sulfate, while the other received a placebo saline solution.
We discovered that those who received magnesium experienced significantly less postoperative nausea and vomiting (PONV) compared to the control group. Specifically, at two hours post-surgery, patients in the magnesium group reported less severe PONV.
Additionally, this group also had lower requirements for remifentanil, a pain reliever, indicating that magnesium not only helps with nausea but may also play a role in overall pain management during recovery. The magnesium levels in the blood after surgery were notably higher in the magnesium group, further supporting its effectiveness.
This research suggests that incorporating magnesium sulfate into treatment protocols during orthognathic surgeries can greatly enhance patient comfort by minimizing nausea and improving pain control.
We discovered that those who received magnesium experienced significantly less postoperative nausea and vomiting (PONV) compared to the control group. Specifically, at two hours post-surgery, patients in the magnesium group reported less severe PONV.
Additionally, this group also had lower requirements for remifentanil, a pain reliever, indicating that magnesium not only helps with nausea but may also play a role in overall pain management during recovery. The magnesium levels in the blood after surgery were notably higher in the magnesium group, further supporting its effectiveness.
This research suggests that incorporating magnesium sulfate into treatment protocols during orthognathic surgeries can greatly enhance patient comfort by minimizing nausea and improving pain control.
Read More
4
We investigated the use of vitamin B6 as a common treatment for nausea and vomiting during pregnancy. There has been an ongoing discussion about how effective high doses of this vitamin actually are, and we wanted to shed light on this issue.
Through a systematic review of literature, we examined various studies, focusing on reports that highlighted the effects of high doses of vitamin B6 on pregnant women experiencing nausea. While we found that many women do turn to vitamin B6 to alleviate their symptoms, particularly during the challenging first trimester, the data also raised serious concerns about potential side effects.
A significant portion of the studies reviewed documented adverse reactions in women taking excessive amounts of vitamin B6. These included neurological symptoms such as burning sensations, tingling, and coordination problems. Alarmingly, we also noted a few cases of miscarriage and intrauterine demise among those studied.
Overall, while vitamin B6 is a widely used treatment for nausea during pregnancy, we must exercise caution. The risks associated with high doses cannot be overlooked, particularly when it comes to the health of both the mother and the developing fetus.
Through a systematic review of literature, we examined various studies, focusing on reports that highlighted the effects of high doses of vitamin B6 on pregnant women experiencing nausea. While we found that many women do turn to vitamin B6 to alleviate their symptoms, particularly during the challenging first trimester, the data also raised serious concerns about potential side effects.
A significant portion of the studies reviewed documented adverse reactions in women taking excessive amounts of vitamin B6. These included neurological symptoms such as burning sensations, tingling, and coordination problems. Alarmingly, we also noted a few cases of miscarriage and intrauterine demise among those studied.
Overall, while vitamin B6 is a widely used treatment for nausea during pregnancy, we must exercise caution. The risks associated with high doses cannot be overlooked, particularly when it comes to the health of both the mother and the developing fetus.
Read More
8
We examined the effects of pyridoxine, or vitamin B6, in reducing postoperative nausea and vomiting (PONV) for patients undergoing elective gynecological laparoscopic surgery. In this study, patients aged 18 to 65 were randomly assigned to receive either pyridoxine or a placebo (normal saline) before anesthesia.
All patients also received a regimen that included dexamethasone and ondansetron, two well-known anti-nausea medications. Reports from the patients indicated that those who received pyridoxine experienced a reduced incidence of nausea and vomiting following their surgery compared to those who received the placebo.
While our findings are promising, it is important to note that pyridoxine was used in conjunction with other medications, making it difficult to ascertain its effect in isolation. Future multicenter studies will help us confirm the effectiveness of pyridoxine in more diverse settings and populations.
All patients also received a regimen that included dexamethasone and ondansetron, two well-known anti-nausea medications. Reports from the patients indicated that those who received pyridoxine experienced a reduced incidence of nausea and vomiting following their surgery compared to those who received the placebo.
While our findings are promising, it is important to note that pyridoxine was used in conjunction with other medications, making it difficult to ascertain its effect in isolation. Future multicenter studies will help us confirm the effectiveness of pyridoxine in more diverse settings and populations.
Read More
Most Useful Reviews
9
No side effects noted
I used to take pharmacy MgB6, but many caused nausea and were ineffective. This magnesium works exceptionally well for me; it has a calming effect, and I feel more resilient to stress without any side effects. Additionally, it's cheaper and easier to take just 1 small tablet twice a day, unlike the large pills I had to take before.
Read More
9
Helpful for nausea
I have been taking this magnesium supplement for two years. It noticeably calms my anxiety before bed and alleviated my cramps and leg pain during my period. Most importantly, it has helped with my nausea and fatigue during pregnancy, proving to be beneficial at various stages of life.
Read More
9
No nausea experienced
Definitely good! This magnesium is absorbed well and did not cause any nausea.
Read More
Medical Researches
SCIENTIFIC SCORE
Possibly Effective
Based on 6 Researches
7.2
- All Researches
9
We explored the effects of a low-opioid anesthesia (LOA) protocol during laparoscopic cholecystectomy and its impact on nausea, vomiting, and pain control. In our study, we compared 40 patients who received LOA, which included magnesium sulfate, with another 40 patients who were given standard opioid-based anesthesia.
While our findings showed that the LOA protocol was more effective in reducing nausea and vomiting compared to traditional opioid analgesia, we didn’t isolate magnesium’s specific role in this improvement. This limitation makes it challenging to determine just how much magnesium alone contributes to reducing nausea.
Nevertheless, the study suggests that using a low-opioid method can enhance patient comfort in the postoperative period. Overall, we found that incorporating non-opioid analgesia and the LOA strategy should be considered more widely in surgical practices.
While our findings showed that the LOA protocol was more effective in reducing nausea and vomiting compared to traditional opioid analgesia, we didn’t isolate magnesium’s specific role in this improvement. This limitation makes it challenging to determine just how much magnesium alone contributes to reducing nausea.
Nevertheless, the study suggests that using a low-opioid method can enhance patient comfort in the postoperative period. Overall, we found that incorporating non-opioid analgesia and the LOA strategy should be considered more widely in surgical practices.
Read More
8
We conducted a study to discover how magnesium sulfate affects nausea during orthognathic surgery. In this research, we divided 75 adult patients into two groups: one group received magnesium sulfate, while the other received a placebo saline solution.
We discovered that those who received magnesium experienced significantly less postoperative nausea and vomiting (PONV) compared to the control group. Specifically, at two hours post-surgery, patients in the magnesium group reported less severe PONV.
Additionally, this group also had lower requirements for remifentanil, a pain reliever, indicating that magnesium not only helps with nausea but may also play a role in overall pain management during recovery. The magnesium levels in the blood after surgery were notably higher in the magnesium group, further supporting its effectiveness.
This research suggests that incorporating magnesium sulfate into treatment protocols during orthognathic surgeries can greatly enhance patient comfort by minimizing nausea and improving pain control.
We discovered that those who received magnesium experienced significantly less postoperative nausea and vomiting (PONV) compared to the control group. Specifically, at two hours post-surgery, patients in the magnesium group reported less severe PONV.
Additionally, this group also had lower requirements for remifentanil, a pain reliever, indicating that magnesium not only helps with nausea but may also play a role in overall pain management during recovery. The magnesium levels in the blood after surgery were notably higher in the magnesium group, further supporting its effectiveness.
This research suggests that incorporating magnesium sulfate into treatment protocols during orthognathic surgeries can greatly enhance patient comfort by minimizing nausea and improving pain control.
Read More
8
We examined the effects of pyridoxine, or vitamin B6, in reducing postoperative nausea and vomiting (PONV) for patients undergoing elective gynecological laparoscopic surgery. In this study, patients aged 18 to 65 were randomly assigned to receive either pyridoxine or a placebo (normal saline) before anesthesia.
All patients also received a regimen that included dexamethasone and ondansetron, two well-known anti-nausea medications. Reports from the patients indicated that those who received pyridoxine experienced a reduced incidence of nausea and vomiting following their surgery compared to those who received the placebo.
While our findings are promising, it is important to note that pyridoxine was used in conjunction with other medications, making it difficult to ascertain its effect in isolation. Future multicenter studies will help us confirm the effectiveness of pyridoxine in more diverse settings and populations.
All patients also received a regimen that included dexamethasone and ondansetron, two well-known anti-nausea medications. Reports from the patients indicated that those who received pyridoxine experienced a reduced incidence of nausea and vomiting following their surgery compared to those who received the placebo.
While our findings are promising, it is important to note that pyridoxine was used in conjunction with other medications, making it difficult to ascertain its effect in isolation. Future multicenter studies will help us confirm the effectiveness of pyridoxine in more diverse settings and populations.
Read More
We conducted a thorough investigation into how combining oral pregabalin and intravenous magnesium sulfate influences nausea in patients undergoing a specific type of spine surgery. In a well-structured trial, 104 participants were randomly assigned to one of four groups, where some received magnesium sulfate with pregabalin, while others received either a placebo or just one of the drugs.
Our primary focus was on how much morphine the patients needed on the first day after surgery, which gives us insight into their pain levels. While we noted the overall benefits of combining these two non-opioid treatments for pain relief, the study did mention postoperative nausea and vomiting as secondary outcomes. However, it's important to clarify that the findings did not specifically highlight any significant advantages of magnesium in reducing nausea when compared to the other treatments or placebos.
In essence, while we observed that the combination of magnesium sulfate and pregabalin effectively reduced opioid consumption and improved pain management post-surgery, it did not yield clear evidence pointing to magnesium's effectiveness specifically for alleviating nausea. This nuanced insight is valuable as we continue exploring the best strategies for managing multiple aspects of patient comfort during the recovery process.
Our primary focus was on how much morphine the patients needed on the first day after surgery, which gives us insight into their pain levels. While we noted the overall benefits of combining these two non-opioid treatments for pain relief, the study did mention postoperative nausea and vomiting as secondary outcomes. However, it's important to clarify that the findings did not specifically highlight any significant advantages of magnesium in reducing nausea when compared to the other treatments or placebos.
In essence, while we observed that the combination of magnesium sulfate and pregabalin effectively reduced opioid consumption and improved pain management post-surgery, it did not yield clear evidence pointing to magnesium's effectiveness specifically for alleviating nausea. This nuanced insight is valuable as we continue exploring the best strategies for managing multiple aspects of patient comfort during the recovery process.
Read More
7
Magnesium reduces post-operative nausea
In our exploration of how magnesium treatment influences nausea, we conducted a double-blind clinical trial with 62 children undergoing tonsillectomy. Participants were divided into two groups, where one received magnesium sulfate and the other lidocaine shortly after intubation.
We observed that while both medications were used, magnesium sulfate appeared to offer benefits over lidocaine. Notably, the group receiving magnesium experienced a significantly lower rate of nausea and vomiting compared to those treated with lidocaine. This points to magnesium's potential effectiveness in managing post-operative nausea.
However, it’s essential to note that our study did not find any significant difference in terms of laryngospasm incidence between the two groups. Overall, magnesium sulfate showcased an advantage with fewer instances of nausea and other distressing symptoms, suggesting its role as a valuable option for patient care in similar surgical scenarios.
We observed that while both medications were used, magnesium sulfate appeared to offer benefits over lidocaine. Notably, the group receiving magnesium experienced a significantly lower rate of nausea and vomiting compared to those treated with lidocaine. This points to magnesium's potential effectiveness in managing post-operative nausea.
However, it’s essential to note that our study did not find any significant difference in terms of laryngospasm incidence between the two groups. Overall, magnesium sulfate showcased an advantage with fewer instances of nausea and other distressing symptoms, suggesting its role as a valuable option for patient care in similar surgical scenarios.
Read More
User Reviews
USERS' SCORE
Good
Based on 5 Reviews
8
- All Reviews
- Positive Reviews
- Negative Reviews
9
No side effects noted
I used to take pharmacy MgB6, but many caused nausea and were ineffective. This magnesium works exceptionally well for me; it has a calming effect, and I feel more resilient to stress without any side effects. Additionally, it's cheaper and easier to take just 1 small tablet twice a day, unlike the large pills I had to take before.
Read More
9
Helpful for nausea
I have been taking this magnesium supplement for two years. It noticeably calms my anxiety before bed and alleviated my cramps and leg pain during my period. Most importantly, it has helped with my nausea and fatigue during pregnancy, proving to be beneficial at various stages of life.
Read More
9
No nausea experienced
Definitely good! This magnesium is absorbed well and did not cause any nausea.
Read More
7.5
Previous nausea experienced
Magnesium with vitamin B6 has greatly improved my nervous system and heart function. I've found I fall asleep quicker and sleep more soundly. Unlike other pharmacy magnesium products that caused nausea, this one has worked well for me and I’ve seen tangible results.
Read More
0
Nausea caused
This magnesium, combined with vitamin B, is the only supplement I take after meals; however, it causes nausea for me.
Read More
Frequently Asked Questions
9
Helpful for nausea
I have been taking this magnesium supplement for two years. It noticeably calms my anxiety before bed and alleviated my cramps and leg pain during my period. Most importantly, it has helped with my nausea and fatigue during pregnancy, proving to be beneficial at various stages of life.
9
No side effects noted
I used to take pharmacy MgB6, but many caused nausea and were ineffective. This magnesium works exceptionally well for me; it has a calming effect, and I feel more resilient to stress without any side effects. Additionally, it's cheaper and easier to take just 1 small tablet twice a day, unlike the large pills I had to take before.
7.5
Previous nausea experienced
Magnesium with vitamin B6 has greatly improved my nervous system and heart function. I've found I fall asleep quicker and sleep more soundly. Unlike other pharmacy magnesium products that caused nausea, this one has worked well for me and I’ve seen tangible results.
0
Nausea caused
This magnesium, combined with vitamin B, is the only supplement I take after meals; however, it causes nausea for me.
9
No nausea experienced
Definitely good! This magnesium is absorbed well and did not cause any nausea.
8
We conducted a study to discover how magnesium sulfate affects nausea during orthognathic surgery. In this research, we divided 75 adult patients into two groups: one group received magnesium sulfate, while the other received a placebo saline solution.
We discovered that those who received magnesium experienced significantly less postoperative nausea and vomiting (PONV) compared to the control group. Specifically, at two hours post-surgery, patients in the magnesium group reported less severe PONV.
Additionally, this group also had lower requirements for remifentanil, a pain reliever, indicating that magnesium not only helps with nausea but may also play a role in overall pain management during recovery. The magnesium levels in the blood after surgery were notably higher in the magnesium group, further supporting its effectiveness.
This research suggests that incorporating magnesium sulfate into treatment protocols during orthognathic surgeries can greatly enhance patient comfort by minimizing nausea and improving pain control.
We discovered that those who received magnesium experienced significantly less postoperative nausea and vomiting (PONV) compared to the control group. Specifically, at two hours post-surgery, patients in the magnesium group reported less severe PONV.
Additionally, this group also had lower requirements for remifentanil, a pain reliever, indicating that magnesium not only helps with nausea but may also play a role in overall pain management during recovery. The magnesium levels in the blood after surgery were notably higher in the magnesium group, further supporting its effectiveness.
This research suggests that incorporating magnesium sulfate into treatment protocols during orthognathic surgeries can greatly enhance patient comfort by minimizing nausea and improving pain control.
7
Magnesium reduces post-operative nausea
In our exploration of how magnesium treatment influences nausea, we conducted a double-blind clinical trial with 62 children undergoing tonsillectomy. Participants were divided into two groups, where one received magnesium sulfate and the other lidocaine shortly after intubation.
We observed that while both medications were used, magnesium sulfate appeared to offer benefits over lidocaine. Notably, the group receiving magnesium experienced a significantly lower rate of nausea and vomiting compared to those treated with lidocaine. This points to magnesium's potential effectiveness in managing post-operative nausea.
However, it’s essential to note that our study did not find any significant difference in terms of laryngospasm incidence between the two groups. Overall, magnesium sulfate showcased an advantage with fewer instances of nausea and other distressing symptoms, suggesting its role as a valuable option for patient care in similar surgical scenarios.
We observed that while both medications were used, magnesium sulfate appeared to offer benefits over lidocaine. Notably, the group receiving magnesium experienced a significantly lower rate of nausea and vomiting compared to those treated with lidocaine. This points to magnesium's potential effectiveness in managing post-operative nausea.
However, it’s essential to note that our study did not find any significant difference in terms of laryngospasm incidence between the two groups. Overall, magnesium sulfate showcased an advantage with fewer instances of nausea and other distressing symptoms, suggesting its role as a valuable option for patient care in similar surgical scenarios.
9
We explored the effects of a low-opioid anesthesia (LOA) protocol during laparoscopic cholecystectomy and its impact on nausea, vomiting, and pain control. In our study, we compared 40 patients who received LOA, which included magnesium sulfate, with another 40 patients who were given standard opioid-based anesthesia.
While our findings showed that the LOA protocol was more effective in reducing nausea and vomiting compared to traditional opioid analgesia, we didn’t isolate magnesium’s specific role in this improvement. This limitation makes it challenging to determine just how much magnesium alone contributes to reducing nausea.
Nevertheless, the study suggests that using a low-opioid method can enhance patient comfort in the postoperative period. Overall, we found that incorporating non-opioid analgesia and the LOA strategy should be considered more widely in surgical practices.
While our findings showed that the LOA protocol was more effective in reducing nausea and vomiting compared to traditional opioid analgesia, we didn’t isolate magnesium’s specific role in this improvement. This limitation makes it challenging to determine just how much magnesium alone contributes to reducing nausea.
Nevertheless, the study suggests that using a low-opioid method can enhance patient comfort in the postoperative period. Overall, we found that incorporating non-opioid analgesia and the LOA strategy should be considered more widely in surgical practices.
We conducted a thorough investigation into how combining oral pregabalin and intravenous magnesium sulfate influences nausea in patients undergoing a specific type of spine surgery. In a well-structured trial, 104 participants were randomly assigned to one of four groups, where some received magnesium sulfate with pregabalin, while others received either a placebo or just one of the drugs.
Our primary focus was on how much morphine the patients needed on the first day after surgery, which gives us insight into their pain levels. While we noted the overall benefits of combining these two non-opioid treatments for pain relief, the study did mention postoperative nausea and vomiting as secondary outcomes. However, it's important to clarify that the findings did not specifically highlight any significant advantages of magnesium in reducing nausea when compared to the other treatments or placebos.
In essence, while we observed that the combination of magnesium sulfate and pregabalin effectively reduced opioid consumption and improved pain management post-surgery, it did not yield clear evidence pointing to magnesium's effectiveness specifically for alleviating nausea. This nuanced insight is valuable as we continue exploring the best strategies for managing multiple aspects of patient comfort during the recovery process.
Our primary focus was on how much morphine the patients needed on the first day after surgery, which gives us insight into their pain levels. While we noted the overall benefits of combining these two non-opioid treatments for pain relief, the study did mention postoperative nausea and vomiting as secondary outcomes. However, it's important to clarify that the findings did not specifically highlight any significant advantages of magnesium in reducing nausea when compared to the other treatments or placebos.
In essence, while we observed that the combination of magnesium sulfate and pregabalin effectively reduced opioid consumption and improved pain management post-surgery, it did not yield clear evidence pointing to magnesium's effectiveness specifically for alleviating nausea. This nuanced insight is valuable as we continue exploring the best strategies for managing multiple aspects of patient comfort during the recovery process.
References
- Hua X, Chen Y, Wu Z, Zheng G, Yang D, et al. Effects of intra-operative magnesium sulfate infusion on orthognathic surgery: A prospective and randomized controlled trial. Heliyon. 2024;10:e30342. 10.1016/j.heliyon.2024.e30342
- Kościuczuk U, Tarnowska K, Rynkiewicz-Szczepanska E. Are There Any Advantages of the Low Opioid Anaesthesia and Non-Opioid Postoperative Analgesia Protocol: A Clinical Observational Study. J Pain Res. 2024;17:941. 10.2147/JPR.S449563
- Tavanaei R, Rezaee-Naserabad SS, Alizadeh S, Yazdani KO, Zali A, et al. Analgesic Effects of Preoperative Combination of Oral Pregabalin and Intravenous Magnesium Sulfate on Postoperative Pain in Patients Undergoing Posterolateral Spinal Fusion Surgery: A 4-arm, Randomized, Double-blind, Placebo-controlled Trial. J Neurosurg Anesthesiol. 2024;36:134. 10.1097/ANA.0000000000000893
- Manouchehrian N, Abbasi R, Jiryaee N, Beigi RM. Comparison of intravenous injection of magnesium sulfate and lidocaine effectiveness on the prevention of laryngospasm and analgesic requirement in tonsillectomy. Eur J Transl Myol. 2022;32. 10.4081/ejtm.2022.10732
- Zhang Q, Ye X, Shi S, Zhou S, Ma D, et al. Pyridoxine Prevents Postoperative Nausea and Vomiting in Gynecological Laparoscopic Surgery: A Double-blind Randomized Controlled Trial. Anesthesiology. 2024. 10.1097/ALN.0000000000005354
- He L, Fan Y, Hu Y, Tian C, Tian Y, et al. The potential hazards of high doses of vitamin B6 in treating nausea and vomiting in pregnancy: A systematic review. Int J Gynaecol Obstet. 2024. 10.1002/ijgo.16032
