We wanted to understand how vitamin A levels impact the severity of eczema in children. In our research, we analyzed clinical data from 159 children diagnosed with eczema, grouping them based on the severity of their condition—mild, moderate, and severe.
Throughout the study, we made some interesting observations. It became clear that as the severity of eczema increased, the levels of vitamin A declined significantly. We also noted a similar trend with vitamin D levels. Meanwhile, certain inflammatory markers such as TG2, IL-4, and IL-13 rose in correlation with worse symptoms.
This relationship was highlighted by our findings indicating a negative correlation between vitamin A and vitamin D levels and the severity of eczema, measured through SCORAD scores. This means as vitamin A levels dropped, the severity of eczema worsened, while increased inflammatory markers suggested intensifying symptoms.
After three months of treatment, all serum levels, including that of vitamin A, improved significantly across all groups. However, while vitamin A appears to be associated with the severity of eczema, we cannot conclude that vitamin A treatment alone effectively alleviates eczema symptoms, as no specific treatment effects were isolated during our analysis.
Overall, we believe that keeping an eye on vitamin A levels, along with these other markers, can give us valuable insights into eczema severity and treatment responses in children.