Overview
SCIENTIFIC SCORE
Questionable
Based on 7 Researches
5.9
USERS' SCORE
Good
Based on 2 Reviews
8.3
Supplement Facts
Serving Size: 1 Softgel
Amount Per Serving
%DV
Calories
5
Vitamin A (100% as natural beta-carotene from D. salina algae)
7,500 mcg
833%
Carotenoid Blend (from D. salina)(providing natural carotenoids: alpha-carotene, cryptoxanthin, zeaxanthin, lutein)
816 mcg
**
Top Medical Research Studies
9
We investigated the impact of vitamin A in treating heart disease, specifically after a myocardial infarction (MI). Our study focused on over 150 cardiac surgery patients, with a particular emphasis on the effects of vitamin A on bone marrow stem cells. We discovered that MI led to harmful changes in these stem cells and that vitamin A, specifically its metabolite 4-oxo-retinoic acid, helps reduce inflammation by calming the stem cells. This approach could improve heart function in the long run after an MI.
Read More
9
We examined how retinoic acid (a form of vitamin A) could promote the repair of heart tissue after injury. Through the use of self-assembling peptides to deliver retinoic acid, we found that it effectively increased the proliferation of heart cells in rats. This treatment also boosted the expression of key genes associated with heart regeneration and improved heart function within four weeks. Overall, our findings suggest that retinoic acid might be a promising strategy to enhance the recovery of damaged heart tissue.
Read More
7
We explored how vitamin A influences heart health in mice with diet-induced obesity. Through a study comparing genetically altered mice with vitamin A deficiencies to normal mice fed a vitamin A-sufficient diet, we found that, despite vitamin A deficiency, the heart's structure, function, and energy production capabilities remained intact after 20 weeks.
Our findings revealed that vitamin A is crucial in maintaining heart-related gene expression linked to energy processes. While the results suggest vitamin A's significant role in preserving cardiac function, they did not indicate a direct benefit in reversing or preventing heart disease in this obesity model.
Our findings revealed that vitamin A is crucial in maintaining heart-related gene expression linked to energy processes. While the results suggest vitamin A's significant role in preserving cardiac function, they did not indicate a direct benefit in reversing or preventing heart disease in this obesity model.
Read More
Most Useful Reviews
7.5
Supports heart health
1 people found this helpful
Great supplement. It's essential for good health, supporting eye health and skin. As an antioxidant, it can lower the risk of coronary artery disease, stroke, macular degeneration, and other age-related diseases when consumed at appropriate levels of beta-carotene.
Read More
7.5
Reduces heart disease risk
The benefits of beta-carotene are significant. Carotene compounds are vital antioxidants, bolstering the immune system, safeguarding against free radicals, and reducing the risk of cancer and heart disease while also slowing mental deterioration with age.
Read More
Medical Researches
SCIENTIFIC SCORE
Questionable
Based on 7 Researches
5.9
- All Researches
9
We investigated the impact of vitamin A in treating heart disease, specifically after a myocardial infarction (MI). Our study focused on over 150 cardiac surgery patients, with a particular emphasis on the effects of vitamin A on bone marrow stem cells. We discovered that MI led to harmful changes in these stem cells and that vitamin A, specifically its metabolite 4-oxo-retinoic acid, helps reduce inflammation by calming the stem cells. This approach could improve heart function in the long run after an MI.
Read More
9
We examined how retinoic acid (a form of vitamin A) could promote the repair of heart tissue after injury. Through the use of self-assembling peptides to deliver retinoic acid, we found that it effectively increased the proliferation of heart cells in rats. This treatment also boosted the expression of key genes associated with heart regeneration and improved heart function within four weeks. Overall, our findings suggest that retinoic acid might be a promising strategy to enhance the recovery of damaged heart tissue.
Read More
8
We examined the connection between serum retinol levels, a marker for vitamin A, and long-term mortality over 30 years. Our analysis involved nearly 29,000 men and revealed that those with higher retinol levels had a 17-32% lower risk of dying from heart disease and other causes compared to those with lower levels.
Interestingly, this beneficial effect held true across various groups, regardless of smoking, drinking, or weight. Although higher retinol is linked to lower mortality, it's important to note that factors like smoking and diabetes played a minimal role in mediation through retinol levels.
Interestingly, this beneficial effect held true across various groups, regardless of smoking, drinking, or weight. Although higher retinol is linked to lower mortality, it's important to note that factors like smoking and diabetes played a minimal role in mediation through retinol levels.
Read More
7
We explored how vitamin A influences heart health in mice with diet-induced obesity. Through a study comparing genetically altered mice with vitamin A deficiencies to normal mice fed a vitamin A-sufficient diet, we found that, despite vitamin A deficiency, the heart's structure, function, and energy production capabilities remained intact after 20 weeks.
Our findings revealed that vitamin A is crucial in maintaining heart-related gene expression linked to energy processes. While the results suggest vitamin A's significant role in preserving cardiac function, they did not indicate a direct benefit in reversing or preventing heart disease in this obesity model.
Our findings revealed that vitamin A is crucial in maintaining heart-related gene expression linked to energy processes. While the results suggest vitamin A's significant role in preserving cardiac function, they did not indicate a direct benefit in reversing or preventing heart disease in this obesity model.
Read More
4
We analyzed data from 7,341 adults aged 65 and older to see how various nutrients affect heart disease.
Our findings revealed that vitamin A, along with other nutrients, was connected with lower heart disease prevalence. Specifically, higher intake of vitamin A was associated with a 5% decrease in risk, among other beneficial effects we noted for different nutrients.
However, while there are some associations, it's crucial to understand that the study found no strong or direct causal relationship between vitamin A and heart disease prevention.
Our findings revealed that vitamin A, along with other nutrients, was connected with lower heart disease prevalence. Specifically, higher intake of vitamin A was associated with a 5% decrease in risk, among other beneficial effects we noted for different nutrients.
However, while there are some associations, it's crucial to understand that the study found no strong or direct causal relationship between vitamin A and heart disease prevention.
Read More
User Reviews
USERS' SCORE
Good
Based on 2 Reviews
8.3
- All Reviews
- Positive Reviews
- Negative Reviews
7.5
Supports heart health
1 people found this helpful
Great supplement. It's essential for good health, supporting eye health and skin. As an antioxidant, it can lower the risk of coronary artery disease, stroke, macular degeneration, and other age-related diseases when consumed at appropriate levels of beta-carotene.
Read More
7.5
Reduces heart disease risk
The benefits of beta-carotene are significant. Carotene compounds are vital antioxidants, bolstering the immune system, safeguarding against free radicals, and reducing the risk of cancer and heart disease while also slowing mental deterioration with age.
Read More
Frequently Asked Questions
No FAQs are available for this product and symptom.
References
- Li W, Liu S, Meng X, Liu H. A nutrient wide association study of cardiovascular disease prevalence in older adults from NHANES 2007 to 2018. Sci Rep. 2025;15:12710. doi:10.1038/s41598-025-97143-8
- Rettkowski J, Romero-Mulero MC, Singh I, Wadle C, Wrobel J, et al. Modulation of bone marrow haematopoietic stem cell activity as a therapeutic strategy after myocardial infarction: a preclinical study. Nat Cell Biol. 2025;27:591. doi:10.1038/s41556-025-01639-4
- Kawai S, Pak K, Iwamoto S, Kawakami C, Inuzuka R, et al. Association Between Maternal Factors in Early Pregnancy and Congenital Heart Defects in Offspring: The Japan Environment and Children's Study. J Am Heart Assoc. 2023;12:e029268. doi:10.1161/JAHA.122.029268
- Tan YZ, Shen HR, Wang YL, Wang QL, Wu XP, et al. Retinoic acid released from self-assembling peptide activates cardiomyocyte proliferation and enhances repair of infarcted myocardium. Exp Cell Res. 2023;422:113440. doi:10.1016/j.yexcr.2022.113440
- Naasner L, Froese N, Hofmann W, Galuppo P, Werlein C, et al. Vitamin A preserves cardiac energetic gene expression in a murine model of diet-induced obesity. Am J Physiol Heart Circ Physiol. 2022;323:H1352. doi:10.1152/ajpheart.00514.2022
- Huang J. Circulating Concentrations of Nutrition-Related Factors Are Not Causally Associated With Atrial Fibrillation: A Mendelian Randomization Study. J Cardiovasc Pharmacol. 2022;80:210. doi:10.1097/FJC.0000000000001263
- Huang J, Weinstein SJ, Yu K, Männistö S, Albanes D. Association between serum retinol and overall and cause-specific mortality in a 30-year prospective cohort study. Nat Commun. 2021;12:6418. doi:10.1038/s41467-021-26639-4
