We encountered a case of a woman suffering from short bowel syndrome, who faced significant hair loss due to biotin deficiency while on home parenteral nutrition. After starting oral biotin supplementation of 10 mg/day for three weeks, we observed that her serum biotin levels increased, leading to noticeable new hair growth and resolution of other symptoms. Further intravenous biotin treatment maintained her on multivitamins that include biotin, preventing any future deficiency symptoms. This case highlights the importance of addressing biotin levels for hair health and overall well-being.
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9.5
Biotin therapy improves hair growth
Biotinidase deficiency characterized by skin and hair findings.
We explored the effects of biotin treatment on hair loss through a case study of a girl diagnosed with biotinidase deficiency. Despite having no notable family history of the condition, her symptoms included problematic dermatitis, yellow hair, and alopecia.
After identifying low levels of biotinase and significant metabolic increases, the girl was found to have two specific mutations in her BTD gene linked to this deficiency. Following the diagnosis, we observed a clear response to biotin supplementation, with an initial dosage of 20 mg per day.
Remarkably, her dermatitis improved within a month, and her hair color returned to normal after three months of treatment. These findings suggest that biotin replacement therapy can have significant positive outcomes in cases related to biotinidase deficiency, connecting biotin to effective hair restoration.
We investigated the effectiveness of biotin as a treatment for hair loss through a literature review focused on available studies. Our search led us to three specific studies that were relevant to the question of whether oral biotin truly supports hair growth or improves hair quality.
One of these studies stood out due to its rigorous design—a double-blind, placebo-controlled trial—but interestingly, it found no significant difference between participants taking biotin and those receiving a placebo when it came to hair growth. The other two studies we examined involved specific groups of patients, such as those on isotretinoin and women who had undergone sleeve gastrectomy. Despite their unique perspectives, these studies were also limited by potential biases and did not provide strong evidence in favor of biotin.
Overall, while biotin has gained immense popularity as a hair supplement among the public, it appears that if one hopes to find robust scientific support for its effectiveness, the evidence is lacking. High-quality research does not substantiate the common belief that biotin can significantly benefit hair health.
Read More
Most Useful Reviews
9
Effective against hair loss
39 people found this helpful
The best recommendation if you’re dealing with serious hair loss issues. The dosage beautifully supports nail health, while my skin feels silky and supple. I witnessed marked improvements by the second month, and I continued for the third to solidify these health benefits. These vitamins are considered the best globally, promising a 100% result. Investing in them is worthwhile, and I advise against experimenting with cheaper alternatives. Was it helpful? Definitely!
Read More
9
Reduced hair loss
14 people found this helpful
A vital vitamin for both beauty and health! Biotin is fantastic for hair and the nervous system. Hair loss and nerves are intertwined. Despite several dietary sources of biotin, I took 800 micrograms for effective results. After about a week, I noticed a threefold reduction in hair loss, and by three weeks, it halted completely. Importantly, I experienced no side effects, unlike with previous vitamin supplements that caused various issues.
Read More
9
Increased hair thickness
10 people found this helpful
It is working for me with no stomach upset. My hair is getting thicker, showing about 2.5 to 3 inches of regrowth. I've noticed considerable changes post-surgery; despite stress and antibiotics, my hair loss has ceased, and I can see regrowth. I'm thrilled with the results from Solgar's product!
The Efficacy and Safety of Dr. SKS Hair Booster Serum (a Cocktail of Micronutrients and Multivitamins) in Adult Males and Females With Androgenetic Alopecia: An Open-Label, Non-randomized, Prospective Study.
We investigated the effectiveness of the Dr. SKS Hair Booster Serum, which contains biotin and other micronutrients, for treating androgenetic alopecia in both men and women. This open-label study included 1,000 participants across multiple clinics in India who received the serum through mesotherapy or derma roller techniques for six months.
During the study, we closely monitored various indicators of hair health, including the amount of hair loss, hair growth rates, and overall hair density changes. Our findings revealed a significant reduction in hair fall and a notable improvement in hair density after treatment. Interestingly, 95% of participants reported satisfaction with the results after six months.
It’s important to note that while biotin is a key ingredient in the serum, the study did not isolate its effects from the other micronutrients, making it challenging to definitively attribute the positive outcomes solely to biotin. No major adverse effects were reported, suggesting a safe treatment profile.
Overall, the study demonstrated that the Dr. SKS Hair Booster Serum could be a viable option for those struggling with hair loss, providing promising results in the context of androgenetic alopecia.
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9.5
Alopecia areata improvement with tofacitinib
Resistant Alopecia Areata Treated with Tofacitinib.
We explored the effectiveness of tofacitinib, a treatment showing promise for alopecia areata (AA), particularly in cases that have proven resistant to other therapies. In one instance, a young adult male with resistant AA had not responded to treatments like oral and topical steroids, minoxidil, and oral troxasalen.
In this study, he received tofacitinib at a dose of 5 mg twice a day along with a biotin supplement. Remarkably, hair regrowth was noted just one month into the treatment, and by the three-month mark, over 90% of his hair had regrown. It’s worth mentioning that no side effects were recorded during the treatment period.
Our findings suggest that while biotin was administered alongside tofacitinib, its specific contributions to hair regrowth outcomes cannot be distinctly isolated. Thus, further research would be necessary to clarify the role of biotin in hair loss treatments.
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9.5
Biotin therapy improves hair growth
Biotinidase deficiency characterized by skin and hair findings.
We explored the effects of biotin treatment on hair loss through a case study of a girl diagnosed with biotinidase deficiency. Despite having no notable family history of the condition, her symptoms included problematic dermatitis, yellow hair, and alopecia.
After identifying low levels of biotinase and significant metabolic increases, the girl was found to have two specific mutations in her BTD gene linked to this deficiency. Following the diagnosis, we observed a clear response to biotin supplementation, with an initial dosage of 20 mg per day.
Remarkably, her dermatitis improved within a month, and her hair color returned to normal after three months of treatment. These findings suggest that biotin replacement therapy can have significant positive outcomes in cases related to biotinidase deficiency, connecting biotin to effective hair restoration.
Read More
9
Dr. SKS Hair Booster efficacy
Efficacy of Dr. SKS Hair Booster Serum in the Treatment of Female Pattern Alopecia in Patients With PCOS: An Open-Label, Non-randomized, Prospective Study.
We explored the effectiveness of Dr. SKS Hair Booster Serum, which contains biotin among other ingredients, in treating female pattern hair loss (FPHL) in women diagnosed with polycystic ovary syndrome (PCOS). Our study included 1,000 females aged 25-50 who experienced hair loss classified as Ludwig grades I and II.
Over six months, participants received the serum through injections in the scalp. We employed various assessment techniques, such as photography and microscopic evaluations, to measure changes in hair growth, thickness, and overall health before and after treatment.
After the treatment period, we observed significant improvements in several key hair parameters, including hair shaft diameter and terminal hair counts, as well as a decrease in unwanted hair. Notably, while biotin is a component of the formula, the study could not isolate its specific effects on hair loss due to the combination of multiple active ingredients.
Importantly, no adverse events were reported during the study, suggesting that Dr. SKS Hair Booster Serum is a safe option for those seeking to manage FPHL associated with PCOS. Overall, this study highlights a promising approach to treating hair loss in this specific patient population.
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9
Biotin improves diffuse hair loss
Efficacy of intramuscular injections of biotin and dexpanthenol in the treatment of diffuse hair loss: A randomized, double-blind controlled study comparing two brands.
We conducted a study to evaluate how effective biotin, when combined with dexpanthenol injections, is at treating diffuse hair loss. In our research, fifty participants suffering from this condition were divided into two groups to receive six weekly injections of different brands of the treatment—one from Pars Behvarzan and the other from Bayer.
After completing the treatment, we assessed the results through various methods like hair fall counts and hair density tests at one and eight weeks post-treatment. We were pleased to find that both treatments significantly helped in reducing hair loss and improving hair density. Specifically, the hair fall count showed remarkable improvement in both groups, while hair density also saw beneficial changes.
Interestingly, while both treatments were effective, we did notice that the Bayer group had a better improvement in the terminal-to-vellus hair ratio when compared to the Pars group at both follow-ups. Overall, our findings suggest that these injections of biotin and dexpanthenol are effective and safe for individuals experiencing diffuse hair loss, offering a reliable option for those looking to enhance their hair health.
The best recommendation if you’re dealing with serious hair loss issues. The dosage beautifully supports nail health, while my skin feels silky and supple. I witnessed marked improvements by the second month, and I continued for the third to solidify these health benefits. These vitamins are considered the best globally, promising a 100% result. Investing in them is worthwhile, and I advise against experimenting with cheaper alternatives. Was it helpful? Definitely!
Read More
9
Reduced hair loss
14 people found this helpful
A vital vitamin for both beauty and health! Biotin is fantastic for hair and the nervous system. Hair loss and nerves are intertwined. Despite several dietary sources of biotin, I took 800 micrograms for effective results. After about a week, I noticed a threefold reduction in hair loss, and by three weeks, it halted completely. Importantly, I experienced no side effects, unlike with previous vitamin supplements that caused various issues.
Read More
9
Increased hair thickness
10 people found this helpful
It is working for me with no stomach upset. My hair is getting thicker, showing about 2.5 to 3 inches of regrowth. I've noticed considerable changes post-surgery; despite stress and antibiotics, my hair loss has ceased, and I can see regrowth. I'm thrilled with the results from Solgar's product!
Read More
9
Best solution tried
8 people found this helpful
This is the best solution for hair loss I've tried! I take it for a month, then take a break, and repeat the course. The price-quality ratio is excellent. After two weeks of use, results come quickly, and I've also seen improvements in my skin and nails. It's a fantastic product; I recommend buying it!
Read More
9
Effective for hair
8 people found this helpful
Hello from Ukraine! I ordered this Biotin after hearing numerous positive reviews about it, which convinced me to get it for my sister, who suffers from seasonal hair loss and brittle nails. My sister takes one capsule—two during her menstrual cycle—and has noticed results after two weeks. She appreciates its efficacy, and we'll continue to order it. Highly recommend!
Hair loss, also known as alopecia, is a common condition that affects both men and women, characterized by the thinning or complete loss of hair from the scalp or other areas of the body. It can occur due to various factors, including genetics, hormonal changes, medical conditions, and environmental factors. The most prevalent type of hair loss is androgenetic alopecia, often referred to as male or female pattern baldness, which typically results in a receding hairline or thinning crown in men and overall thinning in women.
In addition to genetic predisposition, hair loss can be triggered by stress, poor diet, certain medications, and underlying health issues such as thyroid disorders or autoimmune diseases. There are various treatment options available, ranging from over-the-counter products like minoxidil to prescription medications and hair restoration procedures, depending on the severity and cause of hair loss. It's crucial to consult with a healthcare professional to determine the most appropriate treatment plan tailored to individual needs and conditions.
Biotin, also known as vitamin B7, is a water-soluble B-vitamin that plays a crucial role in various metabolic processes in the body. It is essential for converting nutrients into energy and is involved in the synthesis of fatty acids, amino acids, and glucose. Biotin is naturally found in a variety of foods, including eggs, nuts, seeds, fish, meat, dairy products, and certain vegetables. While deficiencies are rare due to its abundance in common diets, they can lead to symptoms such as hair loss, skin rashes, and neurological issues.
Many people take biotin supplements believing they can improve hair, skin, and nail health. Although there is some evidence to support the benefits of biotin for hair growth—especially in those with a deficiency—more research is needed to establish its efficacy for those with sufficient levels. The FDA does not regulate dietary supplements as strictly as medications, so it’s crucial to choose high-quality products from reputable manufacturers. Always consult with a healthcare professional before starting any new supplement to ensure it’s appropriate for your specific needs.
Biotin, also known as vitamin B7, has gained popularity as a supplement for improving hair health and addressing hair loss. While biotin is essential for maintaining healthy skin, nails, and hair, its effectiveness in treating hair loss specifically can vary from person to person. Many studies suggest that biotin deficiency might lead to hair loss, and in those cases, supplementing with biotin can improve hair growth. However, individuals who are not deficient in biotin may not experience significant benefits from additional supplementation.
It's important to note that hair loss can be caused by various factors, including genetics, hormonal changes, and underlying health conditions. Therefore, while biotin may benefit some individuals, it should not be viewed as a one-size-fits-all solution for hair loss. For those experiencing significant thinning or shedding, consulting with a healthcare provider or a dermatologist can yield more tailored recommendations, which might include assessing nutrient levels and exploring other underlying causes of hair loss.
Based on user reviews, the timeline for seeing results from biotin supplements, often used for hair loss, can vary but generally falls within two to four weeks. Many users report noticeable changes in their hair health and reduction in hair loss after about two weeks of consistent usage. For example, one reviewer observed a threefold reduction in hair loss after just one week Read Review, while others noted significant improvements or cessation of hair loss within two to three weeks Read ReviewRead Review.
Additional reports highlight that after a month of usage, improvements become even more pronounced, with new hair growth and increased strength of existing hair being common outcomes experienced by users Read ReviewRead Review. Overall, while individual experiences may vary, many users recommend giving the supplement at least a few weeks to gauge effectiveness.
While biotin is often marketed as a beneficial supplement for hair health, recent scientific research suggests that its efficacy in treating hair loss may not be as robust as commonly believed. A comprehensive literature review examining biotin's role in hair loss revealed limited evidence supporting its effectiveness, highlighting a double-blind, placebo-controlled trial that did not find significant differences in hair growth between biotin and placebo groups [1]. Additional studies have reported that while biotin may provide some benefits when used alongside other active ingredients or treatments, its isolated effects remain largely uncertain [2], [3].
Moreover, specific research has indicated that biotin supplementation may yield positive results primarily in individuals with an existing biotin deficiency [16]. For those experiencing hair loss due to other factors, such as surgery or hormonal changes, the evidence supporting biotin as a standalone treatment is less convincing [14]. Overall, while biotin may play a role in certain contexts and conditions, the scientific community emphasizes the need for further focused investigations to better elucidate its potential benefits in hair loss treatments.
Based on user reviews, many individuals have reported impressive improvements in their hair health and overall appearance while using biotin supplements. Commonly noted outcomes include a significant reduction in hair loss, with some users experiencing a complete halt to hair thinning after just a couple of weeks on the supplement. For example, one user described a threefold decrease in hair loss within the first week Read Review. After a month of use, several reviews indicated visible new hair growth, alongside improvements in skin texture and nail strength Read ReviewRead Review.
In addition to hair loss prevention, users have shared that biotin has also supported nail health and skin vitality. Reports highlight that nails have grown faster and are less prone to splitting, with some users noting enhanced overall skin quality alongside their hair improvement journey Read ReviewRead Review. While individual results may vary, the consensus suggests that many users find biotin an effective solution in their fight against hair loss, making it a popular choice among those looking for similar benefits.
Based on user reviews, many individuals have reported positive experiences when combining biotin with other supplements to manage hair loss. For instance, one reviewer mentioned taking a higher dosage of biotin (10,000 mcg initially, then lowering to 5,000 mcg) and using it alongside vitamin Easy-C, which resulted in improved health and noticeable hair loss reduction Read Review. This suggests that users may benefit from strategic combinations of supplements to enhance their results.
Another user indicated taking biotin in conjunction with proline, which also yielded impressive results in halting hair loss and increasing hair strength Read Review. Overall, many users advocate for experimenting with different supplements in conjunction with biotin to maximize hair health and mitigate hair loss, showcasing a common strategy among those facing similar challenges.
Based on user reviews, a variety of dosages for biotin have been reported for treating hair loss, indicating a nuanced approach to finding the right amount. Some users recommend starting with higher doses, such as 10,000 mcg, then gradually reducing to 5,000 mcg or even 3,000 mcg once results are observed Read Review. Others noted effectiveness at a lower dosage of 800 mcg, with users experiencing significant reductions in hair loss within weeks of consistent use Read Review.
Many reviewers emphasize the importance of consistency in dosage—some recommend taking biotin daily over several weeks or following a cyclical pattern (e.g., a month on, followed by a break) Read Review. For instance, one user mentioned seeing results after taking one capsule daily for three weeks, while another emphasized that their regimen of 5000 mcg contributed significantly to halting hair loss Read Review. Overall, users advocate for individual experimentation to pinpoint the optimal dose that yields the best results while considering their specific hair loss situations.
9
Reduced hair loss
14 people found this helpful
A vital vitamin for both beauty and health! Biotin is fantastic for hair and the nervous system. Hair loss and nerves are intertwined. Despite several dietary sources of biotin, I took 800 micrograms for effective results. After about a week, I noticed a threefold reduction in hair loss, and by three weeks, it halted completely. Importantly, I experienced no side effects, unlike with previous vitamin supplements that caused various issues.
9
Best solution tried
8 people found this helpful
This is the best solution for hair loss I've tried! I take it for a month, then take a break, and repeat the course. The price-quality ratio is excellent. After two weeks of use, results come quickly, and I've also seen improvements in my skin and nails. It's a fantastic product; I recommend buying it!
9
Notable improvement
6 people found this helpful
This biotin is of high quality. Solgar is an excellent brand. This super biotin is the best I’ve used for hair loss. After taking one capsule daily for three weeks, the results are remarkable. I've noticed a significant improvement in my hair and skin, and my nails have stopped peeling and are growing faster. My hair loss has ceased, and new hair is emerging. I take it twice yearly, in spring and autumn.
9
Effective for hair regeneration
2 people found this helpful
These vitamins do an excellent job! I took them during the winter when I experienced significant hair loss and weak nails, plus I had acne. After a month, I noticed new hair growth, and my nails became stronger. I regret not continuing the supplements to further enhance the effects. However, they did not help with acne.
9
Recommended improvement
1 people found this helpful
I decided to take this for severe hair loss. After a month, my hair loss almost completely stopped. I recommend it! Those who upvote this will have a successful day. Don’t believe it? Try it for yourself!
9
Highly recommended
4 people found this helpful
I give it a perfect score! Biotin is incredible—it’s the best supplement I’ve ever taken. After three weeks of use, I've observed noticeable results—my nails no longer split and grow more quickly. Most importantly, my hair loss has stopped, and I've seen the growth of many new strands! I take it biannually: in spring and autumn.
9
Good results
6 people found this helpful
Amazing! These are the only pills that’ve effectively addressed my hair loss problem. After trying countless remedies, the key is to start with a strength of 10,000, follow up with 5000, and then transition to 3000. Gradually reduce if it’s working, and give a like.
9
Effective hair treatment
1 people found this helpful
As a measure against hair loss, I purchase this product with proline and take it. It was surprisingly effective, and I was amazed at the small amount of hair that fell out after shampooing. My hair has become stronger, and I recognise it as an effective solution.
9
Noticeable improvement
1 people found this helpful
I ordered this product on my trichologist's advice due to severe hair loss. The preparation contains biotin in a daily dosage of 5000 mg. The quality is excellent; after a month, I noticed improvement. My hair became stronger and stopped falling out rapidly, with new hair beginning to grow. Additionally, my nails strengthened and my facial skin cleared up.
We investigated the effectiveness of biotin as a treatment for hair loss through a literature review focused on available studies. Our search led us to three specific studies that were relevant to the question of whether oral biotin truly supports hair growth or improves hair quality.
One of these studies stood out due to its rigorous design—a double-blind, placebo-controlled trial—but interestingly, it found no significant difference between participants taking biotin and those receiving a placebo when it came to hair growth. The other two studies we examined involved specific groups of patients, such as those on isotretinoin and women who had undergone sleeve gastrectomy. Despite their unique perspectives, these studies were also limited by potential biases and did not provide strong evidence in favor of biotin.
Overall, while biotin has gained immense popularity as a hair supplement among the public, it appears that if one hopes to find robust scientific support for its effectiveness, the evidence is lacking. High-quality research does not substantiate the common belief that biotin can significantly benefit hair health.
8
Biotin effective in combination therapy
The synergistic effect of phototherapy and active substances on hair growth.
We investigated the effects of biotin as part of a combination therapy aimed at tackling hair loss, particularly in those suffering from androgenic alopecia (AGA). This condition often leads to thinning hair and changes in the hair growth cycle, a problem linked to the hormone dihydrotestosterone (DHT), especially in men.
Each of the key components studied—arginine, arterial extract, and biotin tripeptide-1—was combined with low-level light therapy (LLLT) and was successful in enhancing essential cellular functions like mitochondrial performance, cell growth, and collagen production in skin cells.
Importantly, we noted that biotin worked alongside other substances, and we could see significant improvements in hair follicles. We observed reductions in inflammatory markers and increases in products that promote hair growth. This combined approach holds promise as a comprehensive solution to AGA, effectively addressing both hormonal and cell-based factors contributing to hair loss.
7
Biotin showed no significant benefits
Efficacy of 5% topical minoxidil versus 5 mg oral biotin versus topical minoxidil and oral biotin on hair growth in men: randomized, crossover, clinical trial.
We explored the effects of biotin on hair growth through a randomized, crossover clinical trial that involved different treatment groups. The trial compared 5% topical minoxidil alone, 5 mg oral biotin alone, and a combination of both treatments to see how they impacted hair growth in men.
Despite the inclusion of biotin in the study, the outcomes did not show a significant benefit for hair growth when biotin was used alone. The results suggest that while topical minoxidil may exhibit effective hair growth stimulation, the isolated effects of oral biotin in conjunction with or without minoxidil warrant further study to clarify its actual role.
Consequently, we can conclude that although biotin is often promoted as a hair growth aid, this particular research did not find strong evidence to support its effectiveness on its own, particularly when compared to the known benefits of topical minoxidil.
7
Biotin's impact on hair loss
Biotin: overview of the treatment of diseases of cutaneous appendages and of hyperseborrhea.
We observed that biotin, a crucial B vitamin, could play an important role in addressing hair loss, especially when linked to deficiencies. The study indicates that hair loss treatments may benefit significantly from biotin supplementation if a deficiency is present. This means that identifying low levels of biotin through patient history and blood tests is essential before starting treatment.
When addressing skin conditions like seborrheic dermatitis and comedonal acne, biotin appears to affect the underlying metabolic processes, potentially offering relief. Its good tolerability and lack of risk for overdose make biotin an appealing option for treatment, but it’s important that any supplementation is guided by healthcare professionals to ensure safety and effectiveness.
We need to take a cautious approach, focusing on diagnosing and confirming any deficiencies rather than assuming that biotin will be beneficial in all hair loss cases. Although many anecdotal reports exist about biotin's effectiveness, without clear evidence for all individuals, a tailored approach ensures the best outcomes.
4
Biotin shows limited efficacy
Hair Loss After Sleeve Gastrectomy and Effect of Biotin Supplements.
We observed the occurrence of hair loss in 156 women following laparoscopic sleeve gastrectomy (LSG), a popular procedure for weight loss. Our goal was to determine how common hair loss is after this surgery and whether supplementing with biotin could help.
After undergoing LSG, a significant 72% of the patients reported experiencing hair loss, with most noticing it between three and four months post-surgery. Fortunately, none of the women developed permanent hair loss, but on average, they experienced this condition for about 5.5 months.
To explore biotin's effectiveness, we prescribed 1000 mcg/day of biotin to 22 women who had hair loss linked to biotin deficiency. Only 5 of these women, which is 23%, noticed a significant improvement. Interestingly, there were also 29 women who started taking biotin on their own, even when their blood levels were normal, and 11 of them (38%) reported a meaningful reduction in hair loss.
When we compared the results of biotin use in women with and without deficiency, there was no significant difference in outcomes. Overall, while temporary hair loss after LSG is common, our findings suggest that biotin supplementation does not have a strong effect in reducing this issue.
References
Yelich A, Jenkins H, Holt S, Miller R. Biotin for Hair Loss: Teasing Out the Evidence. J Clin Aesthet Dermatol. 2024;17:56.
Qiu S, Pan Z, Jiang X, Lv G, Feng A, et al. The synergistic effect of phototherapy and active substances on hair growth. J Photochem Photobiol B. 2024;259:113008. doi:10.1016/j.jphotobiol.2024.113008
Valentim FO, Miola AC, Miot HA, Schmitt JV. Efficacy of 5% topical minoxidil versus 5 mg oral biotin versus topical minoxidil and oral biotin on hair growth in men: randomized, crossover, clinical trial. An Bras Dermatol. 2024;99:581. doi:10.1016/j.abd.2023.07.008
Khare S. Efficacy of Dr. SKS Hair Booster Serum in the Treatment of Female Pattern Alopecia in Patients With PCOS: An Open-Label, Non-randomized, Prospective Study. Cureus. 2023;15:e44941. doi:10.7759/cureus.44941
Tr P, Ts R, K SK, Prasanna H. A Comparative Study of Topical Procapil With Platelet-Rich Plasma Therapy Versus Topical Redensyl, Saw Palmetto, and Biotin With Platelet-Rich Plasma Therapy in the Treatment of Androgenetic Alopecia. Cureus. 2023;15:e38696. doi:10.7759/cureus.38696
Khare S. The Efficacy and Safety of Dr. SKS Hair Booster Serum (a Cocktail of Micronutrients and Multivitamins) in Adult Males and Females With Androgenetic Alopecia: An Open-Label, Non-randomized, Prospective Study. Cureus. 2023;15:e37424. doi:10.7759/cureus.37424
Sahay G. Resistant Alopecia Areata Treated with Tofacitinib. Int J Trichology. 2022;14:181. doi:10.4103/ijt.ijt_63_22
Jo H, Kim SY, Kang BH, Baek C, Kwon JE, et al. Cicaria, a Novel Strain Derived from the Human Microbiome, and Its Efficacy as a Treatment for Hair Loss. Molecules. 2022;27. doi:10.3390/molecules27165136
Samadi A, Ketabi Y, Firooz R, Firooz A. Efficacy of intramuscular injections of biotin and dexpanthenol in the treatment of diffuse hair loss: A randomized, double-blind controlled study comparing two brands. Dermatol Ther. 2022;35:e15695. doi:10.1111/dth.15695
Starace M, Gurioli C, Carpanese MA, Bruni F, Piraccini BM, et al. Short anagen syndrome: A case series and algorithm for diagnosis. Pediatr Dermatol. 2021;38:1157. doi:10.1111/pde.14750
Aksac SE, Bilgili SG, Yavuz GO, Yavuz IH, Aksac M, et al. Evaluation of biophysical skin parameters and hair changes in patients with acne vulgaris treated with isotretinoin, and the effect of biotin use on these parameters. Int J Dermatol. 2021;60:980. doi:10.1111/ijd.15485
Yang Y, Yang JY, Chen XJ. Biotinidase deficiency characterized by skin and hair findings. Clin Dermatol. 2020;38:477. doi:10.1016/j.clindermatol.2020.03.004
Şen O, Türkçapar AG. Hair Loss After Sleeve Gastrectomy and Effect of Biotin Supplements. J Laparoendosc Adv Surg Tech A. 2021;31:296. doi:10.1089/lap.2020.0468
Marotta JC, Patel G, Carvalho M, Blakeney S. Clinical Efficacy of a Topical Compounded Formulation in Male Androgenetic Alopecia: Minoxidil 10%, Finasteride 0.1%, Biotin 0.2%, and Caffeine Citrate 0.05% Hydroalcoholic Solution. Int J Pharm Compd. 2020;24:69.
Piraccini BM, Berardesca E, Fabbrocini G, Micali G, Tosti A. Biotin: overview of the treatment of diseases of cutaneous appendages and of hyperseborrhea. G Ital Dermatol Venereol. 2019;154:557. doi:10.23736/S0392-0488.19.06434-4
Sant'Anna Addor FA, Donato LC, Melo CSA. Comparative evaluation between two nutritional supplements in the improvement of telogen effluvium. Clin Cosmet Investig Dermatol. 2018;11:431. doi:10.2147/CCID.S173082
Hayashi A, Mikami Y, Miyamoto K, Kamada N, Sato T, et al. Intestinal Dysbiosis and Biotin Deprivation Induce Alopecia through Overgrowth of Lactobacillus murinus in Mice. Cell Rep. 2017;20:1513. doi:10.1016/j.celrep.2017.07.057
Castro-Gago M, Pérez-Gay L, Gómez-Lado C, Castiñeiras-Ramos DE, Otero-Martínez S, et al. The influence of valproic acid and carbamazepine treatment on serum biotin and zinc levels and on biotinidase activity. J Child Neurol. 2011;26:1522. doi:10.1177/0883073811409227
Castro-Gago M, Gómez-Lado C, Eirís-Puñal J, Díaz-Mayo I, Castiñeiras-Ramos DE. Serum biotinidase activity in children treated with valproic acid and carbamazepine. J Child Neurol. 2010;25:32. doi:10.1177/0883073809336118
Schulpis KH, Karikas GA, Tjamouranis J, Regoutas S, Tsakiris S. Low serum biotinidase activity in children with valproic acid monotherapy. Epilepsia. 2001;42:1359.
Khalidi N, Wesley JR, Thoene JG, Whitehouse WM, Baker WL. Biotin deficiency in a patient with short bowel syndrome during home parenteral nutrition. JPEN J Parenter Enteral Nutr. 1984;8:311.